Imaging Techniques: Essential Tools for the Study of SARS-CoV-2 Infection

COVID‐19‐associated Critical Illness Myopathy with Direct Viral Effects

(2022) Dubravka Dodig et al.   ANNALS OF NEUROLOGY

SARS-CoV-2 non-structural protein 6 triggers NLRP3-dependent pyroptosis by targeting ATP6AP1

(2022) Xiao Sun et al.   CELL DEATH AND DIFFERENTIATION

Pulmonary infection by SARS-CoV-2 induces senescence accompanied by an inflammatory phenotype in severe COVID-19: possible implications for viral mutagenesis

(2022) Konstantinos Evangelou et al.   EUROPEAN RESPIRATORY JOURNAL

SARS-CoV-2 Causes Mitochondrial Dysfunction and Mitophagy Impairment

(2022) Chao Shang et al.   Frontiers in Microbiology

SARS-CoV-2 nucleocapsid protein adheres to replication organelles before viral assembly at the Golgi/ERGIC and lysosome-mediated egress

(2022) Katharina M. Scherer et al.   Science Advances

SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB

(2022) Christopher J. Neufeldt et al.   Communications Biology

Advances in Pathogenesis, Progression, Potential Targets and Targeted Therapeutic Strategies in SARS-CoV-2-Induced COVID-19

(2022) Hong Zhou et al.   Frontiers in Immunology

Postmortem Findings Associated With SARS-CoV-2

(2021) Swati Satturwar et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

SARS-Cov-2 fulminant myocarditis: an autopsy and histopathological case study

(2021) Guillaume Gauchotte et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

SARS-CoV-2 infects cells following viral entry via clathrin-mediated endocytosis

(2021) Armin Bayati et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell-Based High-Throughput Screening Protocol for Discovering Antiviral Inhibitors Against SARS-COV-2 Main Protease (3CLpro)

(2021) Hussin A. Rothan et al.   MOLECULAR BIOTECHNOLOGY

Ocular pathology and occasionally detectable intraocular SARS-CoV-2 RNA in five fatal COVID-19 cases

(2021) Aja Reinhold et al.   OPHTHALMIC RESEARCH

The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein

(2021) Shan Lu et al.   Nature Communications

In Vitro and In Vivo Models for Studying SARS-CoV-2, the Etiological Agent Responsible for COVID-19 Pandemic

(2021) Rafael B. Rosa et al.   Viruses-Basel

Evidences for lipid involvement in SARS-CoV-2 cytopathogenesis

(2021) Roberta Nardacci et al.   Cell Death & Disease

Imaging of SARS-CoV-2 infected Vero E6 cells by helium ion microscopy

(2021) Natalie Frese et al.   Beilstein Journal of Nanotechnology

Morphometry of SARS-CoV and SARS-CoV-2 particles in ultrathin plastic sections of infected Vero cell cultures

(2021) Michael Laue et al.   Scientific Reports

A SARS-CoV-2 cytopathicity dataset generated by high-content screening of a large drug repurposing collection

(2021) Bernhard Ellinger et al.   Scientific Data

Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression

(2021) Ke Zhang et al.   Science Advances

SARS-CoV-2 infects human pancreatic β-cells and elicits β-cell impairment

(2021) Chien-Ting Wu et al.   Cell Metabolism

SARS-CoV-2 infects human adult donor eyes and hESC-derived ocular epithelium

(2021) Anne Z. Eriksen et al.   Cell Stem Cell

Tissue-Based SARS-Cov-2 Detection in Fatal COVID-19 Infections: Sustained Direct Viral-Induced Damage is Not Necessary to Drive Disease Progression

(2021) Siraj M. El Jamal et al.   HUMAN PATHOLOGY

The intersection of COVID-19 and cancer: signaling pathways and treatment implications

(2021) Zhi Zong et al.   Molecular Cancer

SARS-CoV-2 infection of the oral cavity and saliva

(2021) Ni Huang et al.   NATURE MEDICINE

Detection methods for SARS-CoV-2 in tissue

(2021) Saskia von Stillfried et al.   PATHOLOGE

Light Sheet Microscopy-Assisted 3D Analysis of SARS-CoV-2 Infection in the Respiratory Tract of the Ferret Model

(2021) Luca M. Zaeck et al.   Viruses-Basel

FIB-SEM as a Volume Electron Microscopy Approach to Study Cellular Architectures in SARS-CoV-2 and Other Viral Infections: A Practical Primer for a Virologist

(2021) Valentina Baena et al.   Viruses-Basel

SARS-CoV-2: enhancement and segmentation of high-resolution microscopy images—Part I

(2021) Roberto Rodríguez et al.   Signal Image and Video Processing

SARS-CoV-2 ORF6 Disrupts Bidirectional Nucleocytoplasmic Transport through Interactions with Rae1 and Nup98

(2021) Amin Addetia et al.   mBio

Human kidney is a target for novel severe acute respiratory syndrome coronavirus 2 infection

(2021) Bo Diao et al.   Nature Communications

Early postmortem mapping of SARS-CoV-2 RNA in patients with COVID-19 and the correlation with tissue damage

(2021) Stefanie Deinhardt-Emmer et al.   eLife

SARS-CoV-2 cell tropism and multiorgan infection

(2021) Jia Liu et al.   Cell Discovery

The SARS-CoV-2 protein ORF3a inhibits fusion of autophagosomes with lysosomes

(2021) Yabin Zhang et al.   Cell Discovery

Distinct uptake, amplification, and release of SARS-CoV-2 by M1 and M2 alveolar macrophages

(2021) Jiadi Lv et al.   Cell Discovery

Current Strategies of Antiviral Drug Discovery for COVID-19

(2021) Miao Mei et al.   Frontiers in Molecular Biosciences

Microscopic Observation of SARS-Like Particles in RT-qPCR SARS-CoV-2 Positive Sewage Samples

(2021) Djamal Brahim Belhaouari et al.   Pathogens

A standardized definition of placental infection by SARS-CoV-2, a consensus statement from the National Institutes of Health/Eunice Kennedy Shriver National Institute of Child Health and Human Development SARS-CoV-2 Placental Infection Workshop

(2021) Drucilla J. Roberts et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19

(2021) Carmen Mirabelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι

(2021) Yiwen Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SARS-CoV-2: preliminary study of infected human nasopharyngeal tissue by high resolution microscopy

(2021) Brian Mondeja et al.   Virology Journal

Just Seeing Is Not Enough for Believing: Immunolabelling as Indisputable Proof of SARS-CoV-2 Virions in Infected Tissue

(2021) Andreja Erman et al.   Viruses-Basel

Deleterious Effects of SARS-CoV-2 Infection on Human Pancreatic Cells

(2021) Syairah Hanan Shaharuddin et al.   Frontiers in Cellular and Infection Microbiology

Label-free SARS-CoV-2 detection and classification using phase imaging with computational specificity

(2021) Neha Goswami et al.   Light-Science & Applications

SARS-CoV-2 Cellular Entry Is Independent of the ACE2 Cytoplasmic Domain Signaling

(2021) Thankamani Karthika et al.   Cells

Secretory Vesicles Are the Principal Means of SARS-CoV-2 Egress

(2021) Sébastien Eymieux et al.   Cells

The role of autophagy in the pathogenesis of SARS-CoV-2 infection in different cell types

(2021) Nastaran Samimi et al.   Autophagy

ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress

(2021) Di Chen et al.   DEVELOPMENTAL CELL

SARS-CoV-2 induces mitochondrial dysfunction and cell death by oxidative stress/inflammation in leukocytes of COVID-19 patients

(2021) J. De la Cruz-Enríquez et al.   FREE RADICAL RESEARCH

Mitochondrial Dynamics in SARS-COV2 Spike Protein Treated Human Microglia: Implications for Neuro-COVID

(2021) Erin Clough et al.   Journal of Neuroimmune Pharmacology

The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells

(2021) Jan Wenzel et al.   NATURE NEUROSCIENCE

Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation

(2021) Keisuke Tabata et al.   Nature Communications

Contribution of autophagy machinery factors to HCV and SARS-CoV-2 replication organelle formation

(2021) Woan-Ing Twu et al.   Cell Reports

Dual inhibition of TMPRSS2 and Cathepsin B prevents SARS-CoV-2 infection in iPS cells

(2021) Rina Hashimoto et al.   Molecular Therapy-Nucleic Acids

In-House Immunofluorescence Assay for Detection of SARS-CoV-2 Antigens in Cells from Nasopharyngeal Swabs as a Diagnostic Method for COVID-19

(2021) Athene Hoi-Ying Lam et al.   Diagnostics

Multiplex Gene Tagging with CRISPR-Cas9 for Live-Cell Microscopy and Application to Study the Role of SARS-CoV-2 Proteins in Autophagy, Mitochondrial Dynamics, and Cell Growth

(2021) Oscar Perez-Leal et al.   CRISPR Journal

Organ-on-a-chip: recent breakthroughs and future prospects

(2020) Qirui Wu et al.   Biomedical Engineering Online

Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China

(2020) Aiping Wu et al.   Cell Host & Microbe

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

(2020) Manli Wang et al.   CELL RESEARCH

Evidence for gastrointestinal infection of SARS-CoV-2

(2020) Fei Xiao et al.   GASTROENTEROLOGY

Pulmonary pathology of early phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer

(2020) Sufang Tian et al.   Journal of Thoracic Oncology

Selective Naked-Eye Detection of SARS-CoV-2 Mediated by N Gene Targeted Antisense Oligonucleotide Capped Plasmonic Nanoparticles

(2020) Parikshit Moitra et al.   ACS Nano

Molecular Detection of SARS-CoV-2 Infection in FFPE Samples and Histopathologic Findings in Fatal SARS-CoV-2 Cases

(2020) Miroslav Sekulic et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Visualization of SARS-CoV-2 virus invading the human placenta using electron microscopy

(2020) Gabriela N. Algarroba et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2

(2020) Qihui Wang et al.   CELL

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract

(2020) Yixuan J. Hou et al.   CELL

Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient

(2020) Xiao-Hong Yao et al.   CELL RESEARCH

The SARS-CoV-2 outbreak: What we know

(2020) Di Wu et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

SARS-CoV-2 infection of the liver directly contributes to hepatic impairment in patients with COVID-19

(2020) Yijin Wang et al.   JOURNAL OF HEPATOLOGY

Central Nervous System Involvement by Severe Acute Respiratory Syndrome Coronavirus ‐2 (SARS‐CoV‐2)

(2020) Alberto Paniz‐Mondolfi et al.   JOURNAL OF MEDICAL VIROLOGY

Ultrastructural Evidence for Direct Renal Infection with SARS-CoV-2

(2020) Evan A. Farkash et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China

(2020) Hua Su et al.   KIDNEY INTERNATIONAL

Electron microscopy of SARS-CoV-2: a challenging task – Authors' reply

(2020) Zsuzsanna Varga et al.   LANCET

Multiorgan and Renal Tropism of SARS-CoV-2

(2020) Victor G. Puelles et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cathepsin L-selective inhibitors: A potentially promising treatment for COVID-19 patients

(2020) Tianxiao Liu et al.   PHARMACOLOGY & THERAPEUTICS

TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes

(2020) Ruochen Zang et al.   Science Immunology

The Human Coronavirus Disease COVID-19: Its Origin, Characteristics, and Insights into Potential Drugs and Its Mechanisms

(2020) Lo’ai Alanagreh et al.   Pathogens

Detection of SARS-CoV-2 by RNAscope®in situ hybridization and immunohistochemistry techniques

(2020) Mariano Carossino et al.   ARCHIVES OF VIROLOGY

Evidence of SARS-CoV-2 mRNA in endomyocardial biopsies of patients with clinically suspected myocarditis tested negative for COVID-19 in nasopharyngeal swab

(2020) Philip Wenzel et al.   CARDIOVASCULAR RESEARCH

The Global Phosphorylation Landscape of SARS-CoV-2 Infection

(2020) Mehdi Bouhaddou et al.   CELL

SARS-CoV-2 infects human neural progenitor cells and brain organoids

(2020) Bao-Zhong Zhang et al.   CELL RESEARCH

A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids

(2020) Liuliu Yang et al.   Cell Stem Cell

SARS-CoV-2 Orf9b suppresses type I interferon responses by targeting TOM70

(2020) He-wei Jiang et al.   Cellular & Molecular Immunology

Vertical transmission of SARS-CoV-2 infection and preterm birth

(2020) Bianca Pulinx et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Kidney Biopsy Findings in Patients with COVID-19

(2020) Satoru Kudose et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Postmortem Kidney Pathology Findings in Patients with COVID-19

(2020) Dominick Santoriello et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

SARS-CoV-2 Causes a Specific Dysfunction of the Kidney Proximal Tubule

(2020) Alexis Werion et al.   KIDNEY INTERNATIONAL

Detection of SARS-CoV-2 in formalin-fixed paraffin-embedded tissue sections using commercially available reagents

(2020) Alejandro Best Rocha et al.   LABORATORY INVESTIGATION

Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series

(2020) Benjamin T Bradley et al.   LANCET

Comparing SARS-CoV-2 with SARS-CoV and influenza pandemics

(2020) Eskild Petersen et al.   LANCET INFECTIOUS DISEASES

Pulmonary post-mortem findings in a series of COVID-19 cases from northern Italy: a two-centre descriptive study

(2020) Luca Carsana et al.   LANCET INFECTIOUS DISEASES

Neurological associations of COVID-19

(2020) Mark A Ellul et al.   LANCET NEUROLOGY

In situ detection of SARS-CoV-2 in lungs and airways of patients with COVID-19

(2020) Inga-Marie Schaefer et al.   MODERN PATHOLOGY

Human organoids: model systems for human biology and medicine

(2020) Jihoon Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Double-Membrane Vesicles as Platforms for Viral Replication

(2020) Georg Wolff et al.   TRENDS IN MICROBIOLOGY

Transplacental transmission of SARS-CoV-2 infection

(2020) Alexandre J. Vivanti et al.   Nature Communications

A unifying structural and functional model of the coronavirus replication organelle: Tracking down RNA synthesis

(2020) Eric J. Snijder et al.   PLOS BIOLOGY

Therapeutic Strategies Against COVID-19 and Structural Characterization of SARS-CoV-2: A Review

(2020) Gi Uk Jeong et al.   Frontiers in Microbiology

Association of Cardiac Infection With SARS-CoV-2 in Confirmed COVID-19 Autopsy Cases

(2020) Diana Lindner et al.   JAMA Cardiology

Alveolar macrophage dysfunction and cytokine storm in the pathogenesis of two severe COVID-19 patients

(2020) Chaofu Wang et al.   EBioMedicine

Detection of viral SARS‐CoV‐2 genomes and histopathological changes in endomyocardial biopsies

(2020) Felicitas Escher et al.   ESC Heart Failure

TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells

(2020) Dorothea Bestle et al.   Life Science Alliance

iPSCs-Derived Platform: A Feasible Tool for Probing the Neurotropism of SARS-CoV-2

(2020) Xiao-Yuan Mao et al.   ACS Chemical Neuroscience

Quantum Dot-Conjugated SARS-CoV-2 Spike Pseudo-Virions Enable Tracking of Angiotensin Converting Enzyme 2 Binding and Endocytosis

(2020) Kirill Gorshkov et al.   ACS Nano

Comparison of RNA In Situ Hybridization and Immunohistochemistry Techniques for the Detection and Localization of SARS-CoV-2 in Human Tissues

(2020) Lucas R. Massoth et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Chilblains and COVID‐19: why SARS‐CoV‐2 endothelial infection is questioned

(2020) M. Baeck et al.   BRITISH JOURNAL OF DERMATOLOGY

Hunting coronavirus by transmission electron microscopy – a guide to SARS‐CoV‐2‐associated ultrastructural pathology in COVID‐19 tissues

(2020) Helmut Hopfer et al.   HISTOPATHOLOGY

Direct evidence of SARS-CoV-2 in gut endothelium

(2020) Klaus Stahl et al.   INTENSIVE CARE MEDICINE

SARS–CoV-2 infection of the placenta

(2020) Hillary Hosier et al.   JOURNAL OF CLINICAL INVESTIGATION

SARS-CoV-2–triggered neutrophil extracellular traps mediate COVID-19 pathology

(2020) Flavio Protasio Veras et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ultrastructure of cell trafficking pathways and coronavirus: how to recognise the wolf amongst the sheep

(2020) Desley Neil et al.   JOURNAL OF PATHOLOGY

High-Throughput Screening for Inhibitors of the SARS-CoV-2 Protease Using a FRET-Biosensor

(2020) Alistair S. Brown et al.   MOLECULES

SARS-CoV-2 Mpro inhibitors and activity-based probes for patient-sample imaging

(2020) Wioletta Rut et al.   Nature Chemical Biology

NARINGENIN IS A POWERFUL INHIBITOR OF SARS-CoV-2 INFECTION IN VITRO

(2020) Nicola Clementi et al.   PHARMACOLOGICAL RESEARCH

SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling

(2020) Lisa Miorin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Laser spectroscopic technique for direct identification of a single virus I: FASTER CARS

(2020) Volker Deckert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges

(2020) Beata Turoňová et al.   SCIENCE

Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity

(2020) Ludovico Cantuti-Castelvetri et al.   SCIENCE

Histopatological Findings in the Explant Lungs of a Patient With COVID-19 Treated With Bilateral Orthotopic Lung Transplant

(2020) Wei-Ren Luo et al.   TRANSPLANTATION

Post-mortem viral dynamics and tropism in COVID-19 patients in correlation with organ damage

(2020) Kristijan Skok et al.   VIRCHOWS ARCHIV

Infection of Brain Organoids and 2D Cortical Neurons with SARS-CoV-2 Pseudovirus

(2020) Sang Ah Yi et al.   Viruses-Basel

Ultrastructural analysis of SARS-CoV-2 interactions with the host cell via high resolution scanning electron microscopy

(2020) Lucio Ayres Caldas et al.   Scientific Reports

Evasion of Type I Interferon by SARS-CoV-2

(2020) Hongjie Xia et al.   Cell Reports

The Strengths of Scanning Electron Microscopy in Deciphering SARS-CoV-2 Infectious Cycle

(2020) Djamal Brahim Belhaouari et al.   Frontiers in Microbiology

Overexpression of SARS-CoV-2 protein ORF6 dislocates RAE1 and NUP98 from the nuclear pore complex

(2020) Koki Kato et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Microscopy‐based assay for semi‐quantitative detection of SARS‐CoV‐2 specific antibodies in human sera

(2020) Constantin Pape et al.   BIOESSAYS

Integrative Imaging Reveals SARS-CoV-2-Induced Reshaping of Subcellular Morphologies

(2020) Mirko Cortese et al.   Cell Host & Microbe

Expression of SARS-CoV-2 Entry Factors in the Pancreas of Normal Organ Donors and Individuals with COVID-19

(2020) Irina Kusmartseva et al.   Cell Metabolism

ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation

(2020) Guangyan Miao et al.   DEVELOPMENTAL CELL

SARS‐CoV‐2 nucleocapsid protein phase‐separates with RNA and with human hnRNPs

(2020) Theodora Myrto Perdikari et al.   EMBO JOURNAL

Muscle Biopsy Findings in a Case of SARS-CoV-2-Associated Muscle Injury

(2020) Jody E Hooper et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

A Versatile Reporter System to Monitor Virus Infected Cells and Its Application to Dengue Virus and SARS-CoV-2

(2020) Felix Pahmeier et al.   JOURNAL OF VIROLOGY

Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid

(2020) Christiane Iserman et al.   MOLECULAR CELL

Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19

(2020) Jenny Meinhardt et al.   NATURE NEUROSCIENCE

False-negative results of initial RT-PCR assays for COVID-19: A systematic review

(2020) Ingrid Arevalo-Rodriguez et al.   PLoS One

Targeting transcriptional regulation of SARS-CoV-2 entry factors ACE2 and TMPRSS2

(2020) Yuanyuan Qiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Perspective on Organoids for Virology Research

(2020) Adithya Sridhar et al.   Viruses-Basel

Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates

(2020) Adriana Savastano et al.   Nature Communications

Development of immunohistochemistry and in situ hybridisation for the detection of SARS-CoV and SARS-CoV-2 in formalin-fixed paraffin-embedded specimens

(2020) Fabian Z. X. Lean et al.   Scientific Reports

Host metabolism dysregulation and cell tropism identification in human airway and alveolar organoids upon SARS-CoV-2 infection

(2020) Rongjuan Pei et al.   Protein & Cell

Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2–induced systemic toxicity

(2020) Shen Li et al.   JCI Insight

Virus‐Free and Live‐Cell Visualizing SARS‐CoV‐2 Cell Entry for Studies of Neutralizing Antibodies and Compound Inhibitors

(2020) Yali Zhang et al.   Small Methods

Characterizing Viral Infection by Electron Microscopy

(2020) Shreeram Akilesh et al.   AMERICAN JOURNAL OF PATHOLOGY

3D culture models to study SARS-CoV-2 infectivity and antiviral candidates: From spheroids to bioprinting

(2020) Bruna A.G. de Melo et al.   Biomedical Journal

High-throughput Screening and Identification of Potent Broad-spectrum Inhibitors of Coronaviruses

(2019) Liang Shen et al.   JOURNAL OF VIROLOGY

Designing a Green Fluorogenic Protease Reporter by Flipping a Beta Strand of GFP for Imaging Apoptosis in Animals

(2019) Qiang Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Brain-on-a-chip devices for drug screening and disease modeling applications

(2019) Beatrice Miccoli et al.   CURRENT PHARMACEUTICAL DESIGN

SARS coronavirus protein nsp1 disrupts localization of Nup93 from the nuclear pore complex

(2019) Garret N. Gomez et al.   Biochemistry and Cell Biology

Advances in Ex Situ Tissue Optical Clearing

(2019) Paweł Matryba et al.   Laser & Photonics Reviews

Optimization of cell-laden bioinks for 3D bioprinting and efficient infection with influenza A virus

(2018) Johanna Berg et al.   Scientific Reports

A Microfluidic Spheroid Culture Device with a Concentration Gradient Generator for High-Throughput Screening of Drug Efficacy

(2018) Wanyoung Lim et al.   MOLECULES

Light-sheet microscopy for slide-free non-destructive pathology of large clinical specimens

(2017) Adam K. Glaser et al.   Nature Biomedical Engineering

A Bioprinted Liver-on-a-Chip for Drug Screening Applications

(2016) Stephanie Knowlton et al.   TRENDS IN BIOTECHNOLOGY

Engineering an in vitro air-blood barrier by 3D bioprinting

(2015) Lenke Horváth et al.   Scientific Reports

Dual-view plane illumination microscopy for rapid and spatially isotropic imaging

(2014) Abhishek Kumar et al.   Nature Protocols

Three-Dimensional Imaging of Viral Infections

(2014) Cristina Risco et al.   Annual Review of Virology

Micro-scaffold array chip for upgrading cell-based high-throughput drug testing to 3D using benchtop equipment

(2013) Xiaokang Li et al.   LAB ON A CHIP

Spatially isotropic four-dimensional imaging with dual-view plane illumination microscopy

(2013) Yicong Wu et al.   NATURE BIOTECHNOLOGY

Two-photon laser polymerization: from fundamentals to biomedical application in tissue engineering and regenerative medicine

(2012) Manuela T. Raimondi et al.   Journal of Applied Biomaterials & Functional Materials

Evaluation of tip-enhanced Raman spectroscopy for characterizing different virus strains

(2011) Peter Hermann et al.   ANALYST

A miniaturized, optically accessible bioreactor for systematic 3D tissue engineering research

(2011) Matteo Laganà et al.   BIOMEDICAL MICRODEVICES

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

High content screening: seeing is believing

(2010) Fabian Zanella et al.   TRENDS IN BIOTECHNOLOGY

A novel imaging-based high-throughput screening approach to anti-angiogenic drug discovery

(2009) Lasse Evensen et al.   CYTOMETRY PART A