A Microfluidic Spheroid Culture Device with a Concentration Gradient Generator for High-Throughput Screening of Drug Efficacy

The Microwell-mesh: A high-throughput 3D prostate cancer spheroid and drug-testing platform

(2018) E. O. Mosaad et al.   Scientific Reports

Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning

(2018) Sigrid A. Langhans   Frontiers in Pharmacology

Drug screening of biopsy-derived spheroids using a self-generated microfluidic concentration gradient

(2018) Theresa Mulholland et al.   Scientific Reports

Concentration gradient generation methods based on microfluidic systems

(2017) Xiang Wang et al.   RSC Advances

Comparative Analysis of 3D Bladder Tumor Spheroids Obtained by Forced Floating and Hanging Drop Methods for Drug Screening

(2017) Robson L. F. Amaral et al.   Frontiers in Physiology

A 1536-Well 3D Viability Assay to Assess the Cytotoxic Effect of Drugs on Spheroids

(2017) Franck Madoux et al.   SLAS Discovery

Three-Dimensional Cell Cultures in Drug Discovery and Development

(2017) Ye Fang et al.   SLAS Discovery

Microfluidics for cell-based high throughput screening platforms—A review

(2016) Guansheng Du et al.   ANALYTICA CHIMICA ACTA

Drug Discovery Approaches Utilizing Three-Dimensional Cell Culture

(2016) Sarah-Louise Ryan et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Engineering a Brain Cancer Chip for High-throughput Drug Screening

(2016) Yantao Fan et al.   Scientific Reports

High-Throughput 3D Tumor Spheroid Screening Method for Cancer Drug Discovery Using Celigo Image Cytometry

(2016) Sarah Kessel et al.   SLAS Technology

3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

(2016) Michele Zanoni et al.   Scientific Reports

Drug cytotoxicity and signaling pathway analysis with three-dimensional tumor spheroids in a microwell-based microfluidic chip for drug screening

(2015) Yongli Chen et al.   ANALYTICA CHIMICA ACTA

Controllable organization and high throughput production of recoverable 3D tumors using pneumatic microfluidics

(2015) Wenming Liu et al.   LAB ON A CHIP

High-Throughput Cancer Cell Sphere Formation for Characterizing the Efficacy of Photo Dynamic Therapy in 3D Cell Cultures

(2015) Yu-Chih Chen et al.   Scientific Reports

High-Throughput Microfluidic Platform for 3D Cultures of Mesenchymal Stem Cells, Towards Engineering Developmental Processes

(2015) Paola Occhetta et al.   Scientific Reports

Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

(2014) Rasheena Edmondson et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Microscale screening systems for 3D cellular microenvironments: platforms, advances, and challenges

(2014) Sara I. Montanez-Sauri et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A microfluidic-based platform for tumour spheroid culture, monitoring and drug screening

(2014) K. Kwapiszewska et al.   LAB ON A CHIP

Spheroid-based three-dimensional liver-on-a-chip to investigate hepatocyte–hepatic stellate cell interactions and flow effects

(2013) Seung-A Lee et al.   LAB ON A CHIP

An oxygen-permeable spheroid culture system for the prevention of central hypoxia and necrosis of spheroids

(2012) Takahisa Anada et al.   BIOMATERIALS

On-chip anticancer drug test of regular tumor spheroids formed in microwells by a distributive microchannel network

(2012) Choong Kim et al.   LAB ON A CHIP

High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array

(2010) Yi-Chung Tung et al.   ANALYST

Preparation of arrays of cell spheroids and spheroid-monolayer cocultures within a microfluidic device

(2010) Tomoaki Okuyama et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Multicellular tumor spheroids: An underestimated tool is catching up again

(2010) Franziska Hirschhaeuser et al.   JOURNAL OF BIOTECHNOLOGY

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols

Three-Dimensional Cell Culture Matrices: State of the Art

(2008) Jungwoo Lee et al.   TISSUE ENGINEERING PART B-REVIEWS