SARS-CoV-2 non-structural protein 6 triggers NLRP3-dependent pyroptosis by targeting ATP6AP1

Lysosome activation in peripheral blood mononuclear cells and prognostic significance of circulating LC3B in COVID-19

(2021) Shisong Fang et al.   BRIEFINGS IN BIOINFORMATICS

The Variant Gambit: COVID’s Next Move

(2021) Jessica A. Plante et al.   Cell Host & Microbe

Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19

(2021) Igor H. Murai et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Characterization of Disease Severity Associated IgG Subclasses Response in COVID-19 Patients

(2021) Huanle Luo et al.   Frontiers in Immunology

Human nasal and lung tissues infected ex vivo with SARS-CoV-2 provide insights into differential tissue-specific and virus-specific innate immune responses in the upper and lower respiratory tract

(2021) Or Alfi et al.   JOURNAL OF VIROLOGY

COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets

(2021) Toni M. Delorey et al.   NATURE

The SARS-CoV-2 protein ORF3a inhibits fusion of autophagosomes with lysosomes

(2021) Yabin Zhang et al.   Cell Discovery

A Novel Coronavirus from Patients with Pneumonia in China, 2019

(2020) Na Zhu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autophagy in host-microbe interactions

(2020) William K.K. Wu et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

Evolutionary analysis of SARS-CoV-2: how mutation of Non-Structural Protein 6 (NSP6) could affect viral autophagy

(2020) Domenico Benvenuto et al.   JOURNAL OF INFECTION

Epidemiology and transmission of COVID-19 in 391 cases and 1286 of their close contacts in Shenzhen, China: a retrospective cohort study

(2020) Qifang Bi et al.   LANCET INFECTIOUS DISEASES

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

COVID-19: in the footsteps of Ernest Shackleton

(2020) Alvin J Ing et al.   THORAX

Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients

(2020) Tamara S. Rodrigues et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Vitamin D3 activates the autolysosomal degradation function against Helicobacter pylori through the PDIA3 receptor in gastric epithelial cells

(2019) Wei Hu et al.   Autophagy

The phytochemical polydatin ameliorates non‐alcoholic steatohepatitis by restoring lysosomal function and autophagic flux

(2019) Xiaoting Chen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Epithelial cell death markers in bronchoalveolar lavage correlate with chronic lung allograft dysfunction subtypes and survival in lung transplant recipients—a single‐center retrospective cohort study

(2019) Liran Levy et al.   TRANSPLANT INTERNATIONAL

A Bacterial Effector Reveals the V-ATPase-ATG16L1 Axis that Initiates Xenophagy

(2019) Yue Xu et al.   CELL

Autophagy is required for lung development and morphogenesis

(2019) Behzad Yeganeh et al.   JOURNAL OF CLINICAL INVESTIGATION

Manipulation of autophagy by (+) RNA viruses

(2019) Ho Him Wong et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Metformin reduces TRIB3 expression and restores autophagy flux: an alternative antitumor action

(2018) Ke Li et al.   Autophagy

Attenuation of cGAS‐STING signaling is mediated by a p62/SQSTM1‐dependent autophagy pathway activated by TBK1

(2018) Thaneas Prabakaran et al.   EMBO JOURNAL

Inflammasome and Autophagy Regulation: A Two-way Street

(2017) Qian Sun et al.   MOLECULAR MEDICINE

The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity

(2017) Katharina S. Schneider et al.   Cell Reports

Lysosomal Physiology

(2015) Haoxing Xu et al.   Annual Review of Physiology

Bafilomycin A1 disrupts autophagic flux by inhibiting both V-ATPase-dependent acidification and Ca-P60A/SERCA-dependent autophagosome-lysosome fusion

(2015) Caroline Mauvezin et al.   Autophagy

Coronavirus NSP6 restricts autophagosome expansion

(2014) Eleanor M Cottam et al.   Autophagy

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Coronavirus nsp6 proteins generate autophagosomes from the endoplasmic reticulum via an omegasome intermediate

(2011) Eleanor M. Cottam et al.   Autophagy

A Protective Role for Inflammasome Activation Following Injury

(2011) Akinori Osuka et al.   SHOCK

Coronaviruses Hijack the LC3-I-Positive EDEMosomes, ER-Derived Vesicles Exporting Short-Lived ERAD Regulators, for Replication

(2010) Fulvio Reggiori et al.   Cell Host & Microbe

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Inhibition of macroautophagy by bafilomycin A1 lowers proliferation and induces apoptosis in colon cancer cells

(2009) Ya Chun Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

The Signaling Adaptor p62 Is an Important NF-κB Mediator in Tumorigenesis

(2008) Angeles Duran et al.   CANCER CELL