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Title
Targeting the NLRP3 inflammasome in cardiovascular diseases
Authors
Keywords
-
Journal
PHARMACOLOGY & THERAPEUTICS
Volume 236, Issue -, Pages 108053
Publisher
Elsevier BV
Online
2021-12-12
DOI
10.1016/j.pharmthera.2021.108053
References
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- Impaired Autophagy Contributes to Adverse Cardiac Remodeling in Acute Myocardial Infarction
- (2014) Xiaoqian Wu et al. PLoS One
- Effects of Interleukin-1 Blockade With Anakinra on Aerobic Exercise Capacity in Patients With Heart Failure and Preserved Ejection Fraction (from the D-HART Pilot Study)
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- Colchicine for Recurrent Pericarditis (CORP)
- (2013) Massimo Imazio ANNALS OF INTERNAL MEDICINE
- Production and Physiological Effects of Hydrogen Sulfide
- (2013) Hideo Kimura ANTIOXIDANTS & REDOX SIGNALING
- Pirfenidone Attenuates Cardiac Fibrosis in a Mouse Model of TAC-Induced Left Ventricular Remodeling by Suppressing NLRP3 Inflammasome Formation
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- The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia–reperfusion injury
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- Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death
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- Canonical Nlrp3 Inflammasome Links Systemic Low-Grade Inflammation to Functional Decline in Aging
- (2013) Yun-Hee Youm et al. Cell Metabolism
- Targeting Interleukin-1 in Heart Disease
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- Association of nucleotide-binding oligomerization domain-like receptor 3 inflammasome and adverse clinical outcomes in patients with idiopathic dilated cardiomyopathy
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- Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation
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- A Novel Pharmacologic Inhibitor of the NLRP3 Inflammasome Limits Myocardial Injury After Ischemia–Reperfusion in the Mouse
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- The Mitochondrial Antiviral Protein MAVS Associates with NLRP3 and Regulates Its Inflammasome Activity
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- Induction of autophagy contributes to the myocardial protection of valsartan against ischemia-reperfusion injury
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- Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome
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- Comparative Cardiac Toxicity of Anthracyclines In Vitro and In Vivo in the Mouse
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- Critical role of caspase-1 in vascular inflammation and development of atherosclerosis in Western diet-fed apolipoprotein E-deficient mice
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- An Exogenous Hydrogen Sulphide Donor, NaHS, Inhibits the Nuclear Factor ^|^#954;B Inhibitor Kinase/Nuclear Factor ^|^#954;B Inhibitor/Nuclear Factor-^|^#954;B Signaling Pathway and Exerts Cardioprotective Effects in a Rat Hemorrhagic Shock Model
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- Recombinant Human Interleukin-1 Receptor Antagonist Provides Cardioprotection During Myocardial Ischemia Reperfusion in the Mouse
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- Effects of Interleukin-1β Inhibition With Canakinumab on Hemoglobin A1c, Lipids, C-Reactive Protein, Interleukin-6, and Fibrinogen
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- Interleukin-1β blockade improves cardiac remodelling after myocardial infarction without interrupting the inflammasome in the mouse
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- Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation
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- Low-Dose Colchicine for Secondary Prevention of Cardiovascular Disease
- (2012) Stefan M. Nidorf et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Deubiquitination of NLRP3 by BRCC3 Critically Regulates Inflammasome Activity
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- The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP
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- Regulation of inflammasome signaling
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- Enhanced Interleukin-1 Activity Contributes to Exercise Intolerance in Patients with Systolic Heart Failure
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- Critical role for calcium mobilization in activation of the NLRP3 inflammasome
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- Mitochondrial adaptations to physiological vs. pathological cardiac hypertrophy
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- Inflammasome Activation of Cardiac Fibroblasts Is Essential for Myocardial Ischemia/Reperfusion Injury
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- Proatherogenic Effect of Interleukin-18 is Exerted with High-fat Diet, but not with Normal Diet in Spontaneously Hyperlipidemic Mice
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- Basic Calcium Phosphate Crystals Induce Monocyte/Macrophage IL-1 Secretion through the NLRP3 Inflammasome In Vitro
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- Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling
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- The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
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- Alterations in the Interleukin-1/Interleukin-1 Receptor Antagonist Balance Modulate Cardiac Remodeling following Myocardial Infarction in the Mouse
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- Interleukin-1β modulation using a genetically engineered antibody prevents adverse cardiac remodelling following acute myocardial infarction in the mouse
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- BAY 11-7082, a Nuclear Factor-κB Inhibitor, Reduces Inflammation and Apoptosis in a Rat Cardiac Ischemia-Reperfusion Injury Model
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- Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome
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- Interleukin-1 Trap Attenuates Cardiac Remodeling After Experimental Acute Myocardial Infarction in Mice
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- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
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- Toll-like receptors and innate immunity
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- Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
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- Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
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- Cholesterol-dependent cytolysins induce rapid release of mature IL-1β from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner
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- Inflammation in deep vein thrombosis and the development of post-thrombotic syndrome: a prospective study
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- Increased atherosclerotic lesions and Th17 in interleukin-18 deficient apolipoprotein E-knockout mice fed high-fat diet
- (2009) Nada Pejnovic et al. MOLECULAR IMMUNOLOGY
- Inflammation in Alzheimer's disease: Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors
- (2009) Antero Salminen et al. PROGRESS IN NEUROBIOLOGY
- Differential requirement for the activation of the inflammasome for processing and release of IL-1 in monocytes and macrophages
- (2008) M. G. Netea et al. BLOOD
- Anakinra in Experimental Acute Myocardial Infarction—Does Dosage or Duration of Treatment Matter?
- (2008) Fadi N. Salloum et al. CARDIOVASCULAR DRUGS AND THERAPY
- Critical Role of Bone Marrow Apoptosis-Associated Speck-Like Protein, an Inflammasome Adaptor Molecule, in Neointimal Formation After Vascular Injury in Mice
- (2008) Noriyuki Yajima et al. CIRCULATION
- Inhibition of Interleukin-1 by Anakinra Improves Vascular and Left Ventricular Function in Patients With Rheumatoid Arthritis
- (2008) Ignatios Ikonomidis et al. CIRCULATION
- Anakinra, a Recombinant Human Interleukin-1 Receptor Antagonist, Inhibits Apoptosis in Experimental Acute Myocardial Infarction
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