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Regular Intake of Green Tea Polyphenols Suppresses the Development of Nonmelanoma Skin Cancer through miR-29-Mediated Epigenetic Modifications

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Fractionation of Extracts from Black Chokeberry, Cranberry, and Pomegranate to Identify Compounds That Influence Lipid Metabolism

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Integrative Omics to Characterize and Classify Pulmonary Vascular Disease

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(2021) Jing Zhao et al.   Nature Communications

Insights into the role of diet and dietary flavanols in cognitive aging: results of a randomized controlled trial

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(2021) Gurjit Kaur Bhatti et al.   METABOLIC BRAIN DISEASE

Integrated Multi-Omic Analyses of the Genomic Modifications by Gut Microbiome-Derived Metabolites of Epicatechin, 5-(4′-Hydroxyphenyl)-γ-Valerolactone, in TNFalpha-Stimulated Primary Human Brain Microvascular Endothelial Cells

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Effects of Cocoa-Derived Polyphenols on Cognitive Function in Humans. Systematic Review and Analysis of Methodological Aspects

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Lipotoxic Injury Differentially Regulates Brain Microvascular Gene Expression in Male Mice

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Preeclampsia and Increased Permeability Over the Blood–Brain Barrier: A Role of Vascular Endothelial Growth Receptor 2

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Relation of Different Fruit and Vegetable Sources With Incident Cardiovascular Outcomes: A Systematic Review and Meta‐Analysis of Prospective Cohort Studies

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Dietary flavanols improve cerebral cortical oxygenation and cognition in healthy adults

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Propofol attenuated TNF-α-modulated occludin expression by inhibiting Hif-1α/ VEGF/ VEGFR-2/ ERK signaling pathway in hCMEC/D3 cells

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The Western Diet Regulates Hippocampal Microvascular Gene Expression: An Integrated Genomic Analyses in Female Mice

(2019) Saivageethi Nuthikattu et al.   Scientific Reports

Anthocyanins and their gut metabolites attenuate monocyte adhesion and transendothelial migration through nutrigenomic mechanisms regulating endothelial cell permeability

(2018) Irena Krga et al.   FREE RADICAL BIOLOGY AND MEDICINE

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(2018) Javier I. Ottaviani et al.   MOLECULAR ASPECTS OF MEDICINE

Reduced cognitive function, increased blood-brain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr -/-and C57BL/6 mice fed a western diet

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Evaluation at scale of microbiome-derived metabolites as biomarker of flavan-3-ol intake in epidemiological studies

(2018) Javier I. Ottaviani et al.   Scientific Reports

The Role of the Blood Brain Barrier in Neurodegenerative Disorders and their Treatment

(2018) Alan M. Palmer   JOURNAL OF ALZHEIMERS DISEASE

The Impact of Epicatechin on Human Cognition: The Role of Cerebral Blood Flow

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A systems biology network analysis of nutri(epi)genomic changes in endothelial cells exposed to epicatechin metabolites

(2018) Dragan Milenkovic et al.   Scientific Reports

microRNA 221 Targets ADAM10 mRNA and is Downregulated in Alzheimer’s Disease

(2017) Patricia R. Manzine et al.   JOURNAL OF ALZHEIMERS DISEASE

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Lipotoxic brain microvascular injury is mediated by activating transcription factor 3-dependent inflammatory and oxidative stress pathways

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The metabolome of [2-14C](−)-epicatechin in humans: implications for the assessment of efficacy, safety and mechanisms of action of polyphenolic bioactives

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MicroRNA-214 participates in the neuroprotective effect of Resveratrol via inhibiting α-synuclein expression in MPTP-induced Parkinson’s disease mouse

(2015) Zhao-Hui Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Cocoa flavanol intake improves endothelial function and Framingham Risk Score in healthy men and women: a randomised, controlled, double-masked trial: the Flaviola Health Study

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Characterizing blood-brain barrier perturbations after exposure to human triglyceride-rich lipoprotein lipolysis products using MRI in a rat model

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The effect of flavanol-rich cocoa on cerebral perfusion in healthy older adults during conscious resting state: a placebo controlled, crossover, acute trial

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Flavanol metabolites reduce monocyte adhesion to endothelial cells through modulation of expression of genes via p38-MAPK and p65-Nf-kB pathways

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Enhancing dentate gyrus function with dietary flavanols improves cognition in older adults

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(2013) Mario Lorenz   AMERICAN JOURNAL OF CLINICAL NUTRITION

Induction of ATF3 Gene Network by Triglyceride-Rich Lipoprotein Lipolysis Products Increases Vascular Apoptosis and Inflammation

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MiR-29a modulates the angiogenic properties of human endothelial cells

(2013) Zeran Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Duration of T Cell Stimulation Is a Critical Determinant of Cell Fate and Plasticity

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Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic Diseases

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(2012) Mitchell Guttman et al.   NATURE

Modulation of miRNA Expression by Dietary Polyphenols in apoE Deficient Mice: A New Mechanism of the Action of Polyphenols

(2012) Dragan Milenkovic et al.   PLoS One

Nomilin Inhibits Metastasis via Induction of Apoptosis and Regulates the Activation of Transcription Factors and the Cytokine Profile in B16F-10 Cells

(2011) Poyil Pratheeshkumar et al.   INTEGRATIVE CANCER THERAPIES

Catechin hydrate suppresses MCF-7 proliferation through TP53/Caspase-mediated apoptosis

(2011) Ali A Alshatwi   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Biochanin-A, an isoflavon, showed anti-proliferative and anti-inflammatory activities through the inhibition of iNOS expression, p38-MAPK and ATF-2 phosphorylation and blocking NFκB nuclear translocation

(2010) Labanyamoy Kole et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

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(2010) Sheng-Da Hsu et al.   NUCLEIC ACIDS RESEARCH

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(2009) Gabriela Bindea et al.   BIOINFORMATICS

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(2008) C. Urbich et al.   CARDIOVASCULAR RESEARCH

Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation

(2008) Limin Wang et al.   JOURNAL OF LIPID RESEARCH

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/ -secretase expression

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