Lipotoxic brain microvascular injury is mediated by activating transcription factor 3-dependent inflammatory and oxidative stress pathways

A systems biology analysis of brain microvascular endothelial cell lipotoxicity

(2014) Hnin H Aung et al.   BMC Systems Biology

Coordinating calcium signalling

(2014) Kirsty Minton   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Cerebellum, Sensitive Periods, and Autism

(2014) Samuel S.-H. Wang et al.   NEURON

Single-molecule quantification of lipotoxic expression of activating transcription factor 3

(2014) Idir Yahiatène et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Postprandial VLDL lipolysis products increase monocyte adhesion and lipid droplet formation via activation of ERK2 and NFκB

(2013) Laura J. den Hartigh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Induction of ATF3 Gene Network by Triglyceride-Rich Lipoprotein Lipolysis Products Increases Vascular Apoptosis and Inflammation

(2013) Hnin H. Aung et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Targeting lipid sensing in the central nervous system: new therapy against the development of obesity and type 2 diabetes

(2013) Hervé Le Stunff et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Postprandial apoE Isoform and Conformational Changes Associated with VLDL Lipolysis Products Modulate Monocyte Inflammation

(2012) Laura J. den Hartigh et al.   PLoS One

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Inflammation and the Development of Atherosclerosis

(2011) Yoshiko Mizuno et al.   Journal of Atherosclerosis and Thrombosis

Neurovascular dysfunction, inflammation and endothelial activation: Implications for the pathogenesis of Alzheimer's disease

(2011) Paula Grammas   Journal of Neuroinflammation

Cerebellar dysfunction may play an important role in vascular dementia

(2011) Rubo Sui et al.   MEDICAL HYPOTHESES

Vascular Contributions to Cognitive Impairment and Dementia

(2011) Philip B. Gorelick et al.   STROKE

The vascular contribution to Alzheimer's disease

(2010) Robin Altman et al.   CLINICAL SCIENCE

Deficiency of Atf3, an adaptive-response gene, protects islets and ameliorates inflammation in a syngeneic mouse transplantation model

(2010) E. J. Zmuda et al.   DIABETOLOGIA

EPR detection of cellular and mitochondrial superoxide using cyclic hydroxylamines

(2010) Sergey I. Dikalov et al.   FREE RADICAL RESEARCH

Fatty Acids from Very Low-Density Lipoprotein Lipolysis Products Induce Lipid Droplet Accumulation in Human Monocytes

(2010) L. J. den Hartigh et al.   JOURNAL OF IMMUNOLOGY

Dietary fatty acids in dementia and predementia syndromes: Epidemiological evidence and possible underlying mechanisms

(2009) Vincenzo Solfrizzi et al.   AGEING RESEARCH REVIEWS

Hypothalamic lipotoxicity and the metabolic syndrome

(2009) Pablo B. Martínez de Morentin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Saturated with fat: new perspectives on lipotoxicity

(2009) Jeanne Garbarino et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

VLDL lipolysis products increase VLDL fluidity and convert apolipoprotein E4 into a more expanded conformation

(2009) Sarada D. Tetali et al.   JOURNAL OF LIPID RESEARCH

ATF3 transcription factor and its emerging roles in immunity and cancer

(2009) Matthew R. Thompson et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Dietary saturated and unsaturated fats as determinants of blood pressure and vascular function

(2009) Wendy L. Hall   NUTRITION RESEARCH REVIEWS

Dietary fats, cerebrovasculature integrity and Alzheimer’s disease risk

(2009) R. Takechi et al.   PROGRESS IN LIPID RESEARCH

Triglyceride-rich lipoprotein lipolysis increases aggregation of endothelial cell membrane microdomains and produces reactive oxygen species

(2008) Limin Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Repetitive Postprandial Hypertriglyceridemia Induces Monocyte Adhesion to Aortic Endothelial Cells in Goto-Kakizaki Rats

(2008) Kayoko MOTOJIMA et al.   ENDOCRINE JOURNAL

Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation

(2008) Limin Wang et al.   JOURNAL OF LIPID RESEARCH