Reduced cognitive function, increased blood-brain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr -/-and C57BL/6 mice fed a western diet
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Reduced cognitive function, increased blood-brain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr -/-and C57BL/6 mice fed a western diet
Authors
Keywords
Diet, Cognitive impairment, Glucose metabolism, Lipids, Inflammation, Cholesterol, Fatty acids, Lipid metabolism
Journal
PLoS One
Volume 13, Issue 2, Pages e0191909
Publisher
Public Library of Science (PLoS)
Online
2018-02-15
DOI
10.1371/journal.pone.0191909
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Diabetes alters myelin lipid profile in rat cerebral cortex: Protective effects of dihydroprogesterone
- (2017) Gaia Cermenati et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Metabolic perturbations of postnatal growth restriction and hyperoxia-induced pulmonary hypertension in a bronchopulmonary dysplasia model
- (2017) Michael R. La Frano et al. Metabolomics
- Cerebral Blood Flow Measurement by PET in Hypertensive Subjects as a Marker of Cognitive Decline
- (2017) Kazuo Kitagawa JOURNAL OF ALZHEIMERS DISEASE
- Ceramide-Mediated Insulin Resistance and Impairment of Cognitive-Motor Functions
- (2017) Suzanne M. de la Monte et al. JOURNAL OF ALZHEIMERS DISEASE
- The Effects of a High-Energy Diet on Hippocampal Function and Blood-Brain Barrier Integrity in the Rat
- (2017) Scott E. Kanoski et al. JOURNAL OF ALZHEIMERS DISEASE
- Chronic Cigarette Smoking in Healthy Middle-Aged Individuals Is Associated With Decreased Regional Brain N-acetylaspartate and Glutamate Levels
- (2016) Timothy C. Durazzo et al. BIOLOGICAL PSYCHIATRY
- Unique plasma metabolomic signatures of individuals with inherited disorders of long-chain fatty acid oxidation
- (2016) Colin S. McCoin et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Sweat lipid mediator profiling: a noninvasive approach for cutaneous research
- (2016) Karan Agrawal et al. JOURNAL OF LIPID RESEARCH
- Meal rich in carbohydrate, but not protein or fat, reveals adverse immunometabolic responses associated with obesity
- (2016) Ehsan Parvaresh Rizi et al. Nutrition Journal
- Brain and cognition abnormalities in long-term anabolic-androgenic steroid users
- (2015) Marc J. Kaufman et al. DRUG AND ALCOHOL DEPENDENCE
- 18-Carbon polyunsaturated fatty acids ameliorate palmitate-induced inflammation and insulin resistance in mouse C2C12 myotubes
- (2015) Pei-Yin Chen et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Hippocampal proton MR spectroscopy as a novel approach in the assessment of radiation injury and the correlation to neurocognitive function impairment: initial experiences
- (2015) Petr Pospisil et al. Radiation Oncology
- A high calorie diet causes memory loss, metabolic syndrome and oxidative stress into hippocampus and temporal cortex of rats
- (2015) Samuel Treviño et al. SYNAPSE
- Increased PUFA Content and 5-Lipoxygenase Pathway Expression Are Associated with Subcutaneous Adipose Tissue Inflammation in Obese Women with Type 2 Diabetes
- (2015) Mattijs Heemskerk et al. Nutrients
- Mediterranean Diet and Age-Related Cognitive Decline
- (2015) Cinta Valls-Pedret et al. JAMA Internal Medicine
- Rapid publication-ready MS-Word tables for two-way ANOVA
- (2015) Houssein I Assaad et al. SpringerPlus
- Higher Glutamate + Glutamine and Reduction of N-acetylaspartate in Posterior Cingulate According to Age Range in Patients with Cognitive Impairment and/or Pain
- (2014) Nicolás Fayed et al. ACADEMIC RADIOLOGY
- A systems biology analysis of brain microvascular endothelial cell lipotoxicity
- (2014) Hnin H Aung et al. BMC Systems Biology
- Short-Term High-Fat-and-Fructose Feeding Produces Insulin Signaling Alterations Accompanied by Neurite and Synaptic Reduction and Astroglial Activation in the Rat Hippocampus
- (2014) Erika Calvo-Ochoa et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Decreased carbon shunting from glucose toward oxidative metabolism in diet-induced ketotic rat brain
- (2014) Yifan Zhang et al. JOURNAL OF NEUROCHEMISTRY
- CSF lactate levels, τ proteins, cognitive decline: a dynamic relationship in Alzheimer's disease
- (2014) C Liguori et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Dietary fat composition and dementia risk
- (2014) Martha Clare Morris et al. NEUROBIOLOGY OF AGING
- Acute effects of a dietary non-starch polysaccharide supplement on cognitive performance in healthy middle-aged adults
- (2014) Talitha Best et al. NUTRITIONAL NEUROSCIENCE
- Single-molecule quantification of lipotoxic expression of activating transcription factor 3
- (2014) Idir Yahiatène et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Comprehensive analysis of lipids in biological systems by liquid chromatography-mass spectrometry
- (2014) Tomas Cajka et al. TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- The role of n − 6 and n − 3 polyunsaturated fatty acids in the manifestation of the metabolic syndrome in cardiovascular disease and non-alcoholic fatty liver disease
- (2014) Jessica Monteiro et al. Food & Function
- A Phenotypic Change But Not Proliferation Underlies Glial Responses in Alzheimer Disease
- (2013) Alberto Serrano-Pozo et al. AMERICAN JOURNAL OF PATHOLOGY
- Induction of ATF3 Gene Network by Triglyceride-Rich Lipoprotein Lipolysis Products Increases Vascular Apoptosis and Inflammation
- (2013) Hnin H. Aung et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro
- (2013) Vibol Chhor et al. BRAIN BEHAVIOR AND IMMUNITY
- Short exposure to a diet rich in both fat and sugar or sugar alone impairs place, but not object recognition memory in rats
- (2013) Jessica E. Beilharz et al. BRAIN BEHAVIOR AND IMMUNITY
- Oxidative stress and APO E polymorphisms in Alzheimer's disease and in mild cognitive impairment
- (2013) L. Chico et al. FREE RADICAL RESEARCH
- LipidBlast in silico tandem mass spectrometry database for lipid identification
- (2013) Tobias Kind et al. NATURE METHODS
- Damaging effects of a high-fat diet to the brain and cognition: A review of proposed mechanisms
- (2013) Linnea R. Freeman et al. NUTRITIONAL NEUROSCIENCE
- Chronic restricted access to 10% sucrose solution in adolescent and young adult rats impairs spatial memory and alters sensitivity to outcome devaluation
- (2013) Michael D. Kendig et al. PHYSIOLOGY & BEHAVIOR
- Continuation of Exercise Is Necessary to Inhibit High Fat Diet-Induced β-Amyloid Deposition and Memory Deficit in Amyloid Precursor Protein Transgenic Mice
- (2013) Masato Maesako et al. PLoS One
- Multifunctional role of astrocytes as gatekeepers of neuronal energy supply
- (2013) Jillian L. Stobart et al. Frontiers in Cellular Neuroscience
- Metabolomics and Mass Isotopomer Analysis as a Strategy for Pathway Discovery: Pyrrolyl and Cyclopentenyl Derivatives of the Pro-Drug of Abuse, Levulinate
- (2012) Stephanie R. Harris et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Dietary regulation of catabolic disposal of 4-hydroxynonenal analogs in rat liver
- (2012) Qingling Li et al. FREE RADICAL BIOLOGY AND MEDICINE
- TGF-β signaling through SMAD2/3 induces the quiescent microglial phenotype within the CNS environment
- (2012) Shai Abutbul et al. GLIA
- A Reversible Early Oxidized Redox State That Precedes Macromolecular ROS Damage in Aging Nontransgenic and 3xTg-AD Mouse Neurons
- (2012) D. Ghosh et al. JOURNAL OF NEUROSCIENCE
- Restoration of dietary-fat induced blood–brain barrier dysfunction by anti-inflammatory lipid-modulating agents
- (2012) Menuka Pallebage-Gamarallage et al. Lipids in Health and Disease
- Parkin prevents cortical atrophy and Aβ-induced alterations of brain metabolism: 13C NMR and magnetic resonance imaging studies in AD models
- (2012) Norah Algarzae et al. NEUROSCIENCE
- The effects of a high-energy diet on hippocampal-dependent discrimination performance and blood–brain barrier integrity differ for diet-induced obese and diet-resistant rats
- (2012) Terry L. Davidson et al. PHYSIOLOGY & BEHAVIOR
- The metabolomic profile during isoflurane anesthesia differs from propofol anesthesia in the live rodent brain
- (2011) Rany Makaryus et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Neuroprotective and Ameliorative Actions of Polyunsaturated Fatty Acids Against Neuronal Diseases: Beneficial Effect of Docosahexaenoic Acid on Cognitive Decline in Alzheimer’s Disease
- (2011) Michio Hashimoto et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Positive correlation between elevated plasma cholesterol levels and cognitive impairments in LDL receptor knockout mice: relevance of cortico-cerebral mitochondrial dysfunction and oxidative stress
- (2011) J. de Oliveira et al. NEUROSCIENCE
- Brain Glucose Metabolism in Vascular White Matter Disease With Dementia
- (2010) Belen Pascual et al. STROKE
- Is Sticky Blood Bad for the Brain?
- (2009) John Gallacher et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- 5-lipoxygenase deficiency reduces hepatic inflammation and tumor necrosis factor α-induced hepatocyte damage in hyperlipidemia-prone ApoE-null mice
- (2009) Marcos Martínez-Clemente et al. HEPATOLOGY
- Catabolism of 4-Hydroxyacids and 4-Hydroxynonenal via 4-Hydroxy-4-phosphoacyl-CoAs
- (2009) Guo-Fang Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord
- (2009) K. A. Kigerl et al. JOURNAL OF NEUROSCIENCE
- Estrogen regulation of glucose metabolism and mitochondrial function: Therapeutic implications for prevention of Alzheimer's disease☆
- (2008) Roberta Diaz Brinton ADVANCED DRUG DELIVERY REVIEWS
- The Netherlands protocol for standardisation and quantification of FDG whole body PET studies in multi-centre trials
- (2008) Ronald Boellaard et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Triglyceride Synthesis in Epididymal Adipose Tissue
- (2008) Ilya R. Bederman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics
- (2008) Vitali Matyash et al. JOURNAL OF LIPID RESEARCH
- High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice
- (2008) Lakshmi Thirumangalakudi et al. JOURNAL OF NEUROCHEMISTRY
- Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study
- (2008) M D M Haag et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Inflammatory changes are tightly associated with neurodegeneration in the brain and spinal cord of the APP/PS1KI mouse model of Alzheimer's disease
- (2008) Oliver Wirths et al. NEUROBIOLOGY OF AGING
- Behavioral consequences of ovarian atrophy and estrogen replacement in the APPswe mouse
- (2007) Mari S. Golub et al. NEUROBIOLOGY OF AGING
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation