Stereodivergent Construction of 1,4‐Nonadjacent Stereocenters via Hydroalkylation of Racemic Allylic Alcohols Enabled by Copper/Ruthenium Relay Catalysis

Diastereodivergent Synthesis of Chiral α-Aminoketones via a Catalytic O–H Insertion/Barnes–Claisen Rearrangement Reaction

(2022) Yun Liu et al.   ACS Catalysis

Catalytic Asymmetric Benzylation of Azomethine Ylides Enabled by Synergistic Lewis Acid/Palladium Catalysis

(2022) Xin Chang et al.   ORGANIC LETTERS

Stereodivergent propargylic alkylation of enals via cooperative NHC and copper catalysis

(2022) Yu-Hua Wen et al.   Nature Communications

Stereodivergent total synthesis of rocaglaol initiated by synergistic dual-metal-catalyzed asymmetric allylation of benzofuran-3(2H)-one

(2022) Yang Xu et al.   Chem

Stereodivergent Synthesis of Tertiary Fluoride-Tethered Allenes via Copper and Palladium Dual Catalysis

(2021) Shao-Qian Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Challenges and Opportunities in Multicatalysis

(2021) Sebastián Martínez et al.   ACS Catalysis

Enantio‐ and Diastereodivergent Sequential Catalysis Featuring Two Transition‐Metal‐Catalyzed Asymmetric Reactions

(2021) Jeanne Masson‐Makdissi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantio‐ and Diastereodivergent Synthesis of Spirocycles through Dual‐Metal‐Catalyzed [3+2] Annulation of 2‐Vinyloxiranes with Nucleophilic Dipoles

(2021) Youbin Peng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Diastereo‐ and Enantioconvergent Synthesis of Vicinal Diamines from Diols through Borrowing Hydrogen

(2021) Hui‐Jie Pan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantio- and Diastereodivergent Construction of 1,3-Nonadjacent Stereocenters Bearing Axial and Central Chirality through Synergistic Pd/Cu Catalysis

(2021) Jiacheng Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synergistic Pd/Amine-Catalyzed Stereodivergent Hydroalkylation of 1,3-Dienes with Aldehydes: Reaction Development, Mechanism, and Stereochemical Origins

(2021) Hongfa Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Synthesis of Enantioenriched 2,3-Disubstituted Dihydrobenzofurans via a One-Pot C–H Functionalization/Oxa-Michael Addition Cascade

(2021) Dong-Xing Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Redox-enabled direct stereoconvergent heteroarylation of simple alcohols

(2021) Yongbing Liu et al.   Nature Communications

Stereodivergent Synthesis of Enantioenriched γ‐Butyrolactones Bearing Two Vicinal Stereocenters Enabled by Synergistic Copper and Iridium Catalysis

(2021) Lu Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Understanding Halide Counterion Effects in Enantioselective Ruthenium-Catalyzed Carbonyl (α-Aryl)allylation: Alkynes as Latent Allenes and Trifluoroethanol-Enhanced Turnover in The Conversion of Ethanol to Higher Alcohols via Hydrogen Auto-transfer

(2021) Eliezer Ortiz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tandem Insertion/[1,3]-rearrangement: Highly Enantioselective Construction of α-Aminoketones

(2020) Yushuang Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Reactions with N-Metallated Azomethine Ylides

(2020) Liang Wei et al.   ACCOUNTS OF CHEMICAL RESEARCH

Asymmetric Guerbet Reaction to Access Chiral Alcohols

(2020) Kun Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Room‐Temperature Guerbet Reaction with Unprecedented Catalytic Efficiency and Enantioselectivity

(2020) Teng Wei Ng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Control of Absolute Stereochemistry in Transition‐Metal‐Catalyzed Hydrogen Borrowing Reactions

(2020) Timothy Kwok et al.   CHEMISTRY-A EUROPEAN JOURNAL

Stereodivergent Pd/Cu Catalysis for the Dynamic Kinetic Asymmetric Transformation of Racemic Unsymmetrical 1,3-Disubstituted Allyl Acetates

(2020) Rui He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synergistic Catalysis with Azomethine Ylides

(2020) Liang Wei et al.   CHINESE JOURNAL OF CHEMISTRY

Stereodivergent Synthesis of α-Quaternary Serine and Cysteine Derivatives Containing Two Contiguous Stereogenic Centers via Synergistic Cu/Ir Catalysis

(2020) Hui-Min Wu et al.   ORGANIC LETTERS

Enantioselective hydrogenation of dialkyl ketones

(2020) Feng-Hua Zhang et al.   Nature Catalysis

Anti‐Markovnikov Hydroamination of Racemic Allylic Alcohols to Access Chiral γ‐Amino Alcohols

(2020) Ruirui Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of γ-Secondary Amino Alcohols via a Borrowing-Hydrogen Cascade

(2020) Yupeng Pan et al.   ORGANIC LETTERS

Diastereodivergent Synthesis of β‐Amino Alcohols through Dual‐Metal‐Catalyzed Coupling of Alkoxyallenes with Aldimine Esters

(2020) Weiwei Zi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic Dual Transition Metal Catalysis

(2020) U Bin Kim et al.   CHEMICAL REVIEWS

Stereodivergent Carbon–Carbon Bond Formation between Iminium and Enolate Intermediates by Synergistic Organocatalysis

(2020) Byungjun Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Synthesis through Catalytic Asymmetric Reversed Hydroboration

(2019) Tao-Tao Gao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chirality-Economy Catalysis: Asymmetric Transfer Hydrogenation of Ketones by Ru-Catalysts of Minimal Stereogenicity

(2019) Fumin Chen et al.   ACS Catalysis

Catalytic Asymmetric Synthesis of Cyclohexanes by Hydrogen Borrowing Annulations

(2019) Roly Armstrong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent Construction of Tertiary Fluorides in Vicinal Stereogenic Pairs by Allylic Substitution with Iridium and Copper Catalysts

(2019) Zhi-Tao He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synergistic catalysis for cascade allylation and 2-aza-cope rearrangement of azomethine ylides

(2019) Liang Wei et al.   Nature Communications

Synergetic iridium and amine catalysis enables asymmetric [4+2] cycloadditions of vinyl aminoalcohols with carbonyls

(2019) Mao-Mao Zhang et al.   Nature Communications

Stereodivergent Coupling of 1,3-Dienes with Aldimine Esters Enabled by Synergistic Pd and Cu Catalysis

(2019) Qinglong Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synergistic Pd/Cu Catalysis in Organic Synthesis

(2019) Yue Wu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Sequence-Dependent Stereodivergent Allylic Alkylation/Fluorination of Acyclic Ketones

(2019) Xi-Jia Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent assembly of tetrahydro-γ-carbolines via synergistic catalytic asymmetric cascade reaction

(2019) Shi-Ming Xu et al.   Nature Communications

Diastereodivergent synthesis of enantioenriched α,β-disubstituted γ-butyrolactones via cooperative N-heterocyclic carbene and Ir catalysis

(2019) Santanu Singha et al.   Nature Catalysis

Stereodivergent Catalysis

(2018) Irina P. Beletskaya et al.   CHEMICAL REVIEWS

Advances in One-Pot Synthesis through Borrowing Hydrogen Catalysis

(2018) Avelino Corma et al.   CHEMICAL REVIEWS

Stereodivergent Synthesis of α,α-Disubstituted α-Amino Acids via Synergistic Cu/Ir Catalysis

(2018) Liang Wei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Allylation of Azaaryl Acetamides and Acetates by Synergistic Iridium and Copper Catalysis

(2018) Xingyu Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ir/Cu Dual Catalysis: Enantio- and Diastereodivergent Access to α,α-Disubstituted α-Amino Acids Bearing Vicinal Stereocenters

(2018) Xiaohong Huo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

From determination of enantiopurity to the construction of complex molecules: The Horeau principle and its application in synthesis

(2018) Andrew M. Harned   TETRAHEDRON

Stereodivergent synthesis of vicinal quaternary-quaternary stereocenters and bioactive hyperolactones

(2018) Haifeng Zheng et al.   Nature Communications

Stereodivergent synthesis of 1,4-dicarbonyls by traceless charge–accelerated sulfonium rearrangement

(2018) Dainis Kaldre et al.   SCIENCE

Synergistic Cu/Pd Catalysis for Enantioselective Allylation of Ketimine Esters: The Direct Synthesis of α-Substituted α-Amino Acids and 2H- Pyrrols

(2018) Liang Wei et al.   ADVANCED SYNTHESIS & CATALYSIS

3d-Metal Catalyzed N- and C-Alkylation Reactions via Borrowing Hydrogen or Hydrogen Autotransfer

(2018) Torsten Irrgang et al.   CHEMICAL REVIEWS

Stereoselective and Site-Specific Allylic Alkylation of Amino Acids and Small Peptides via a Pd/Cu Dual Catalysis

(2017) Xiaohong Huo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Coupling of Aldehydes and Alkynes via Synergistic Catalysis Using Rh and Jacobsen’s Amine

(2017) Faben A. Cruz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergence in Asymmetric Catalysis

(2017) Simon Krautwald et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Complete diastereodivergence in asymmetric 1,6-addition reactions enabled by minimal modification of a chiral catalyst

(2017) Daisuke Uraguchi et al.   Nature Communications

(Enantio)selective Hydrogen Autotransfer: Ruthenium-Catalyzed Synthesis of Oxazolidin-2-ones from Urea and Diols

(2016) Miguel Peña-López et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Transfer Hydrogenation of Imines using Alcohol: Efficiency and Selectivity are Influenced by the Hydrogen Donor

(2016) Hui-Jie Pan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic enantioselective OFF ↔ ON activation processes initiated by hydrogen transfer: concepts and challenges

(2016) Adrien Quintard et al.   CHEMICAL COMMUNICATIONS

An Ir/Zn Dual Catalysis for Enantio- and Diastereodivergent α-Allylation of α-Hydroxyketones

(2016) Xiaohong Huo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Allylic Substitutions with Aryl Acetic Acid Esters by Synergistic Iridium and Lewis Base Catalysis

(2016) Xingyu Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-catalysed enantioselective stereodivergent synthesis of amino alcohols

(2016) Shi-Liang Shi et al.   NATURE

Triple Iron/Copper/Iminium Activation for the Efficient Redox Neutral Catalytic Enantioselective Functionalization of Allylic Alcohols

(2016) Mylène Roudier et al.   ACS Catalysis

Acid-Assisted Ru-Catalyzed Enantioselective Amination of 1,2-Diols through Borrowing Hydrogen

(2016) Li-Cheng Yang et al.   ACS Catalysis

Stereodivergent Dual Catalytic α-Allylation of Protected α-Amino- and α-Hydroxyacetaldehydes

(2015) Tobias Sandmeier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric γ-Allylation of α,β-Unsaturated Aldehydes by Combined Organocatalysis and Transition-Metal Catalysis

(2015) Line Naesborg et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Substitution of alcohols by N-nucleophiles via transition metal-catalyzed dehydrogenation

(2015) Qin Yang et al.   CHEMICAL SOCIETY REVIEWS

Dynamic Kinetic Asymmetric Amination of Alcohols: From A Mixture of Four Isomers to Diastereo- and Enantiopure α-Branched Amines

(2015) Zi-Qiang Rong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades

(2015) F. G. Mutti et al.   SCIENCE

Asymmetric Organocatalysis Combined with Metal Catalysis: Concept, Proof of Concept, and Beyond

(2014) Dian-Feng Chen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Catalytic Enantioselective CH Functionalization of Alcohols by Redox-Triggered Carbonyl Addition: Borrowing Hydrogen, Returning Carbon

(2014) John M. Ketcham et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent α-Allylation of Linear Aldehydes with Dual Iridium and Amine Catalysis

(2014) Simon Krautwald et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Cascade Formal Reductive Insertion of Allylic Alcohols into the C(O)–C Bond of 1,3-Diketones: Ready Access to Synthetically Valuable 3-Alkylpentanol Units

(2014) Mylène Roudier et al.   ORGANIC LETTERS

Catalytic Asymmetric Construction of Azabicyclo[2.2.1]heptanes Bearing Two Quaternary Stereogenic Centers via Silver(I)-Catalyzed 1,3-Dipolar Cyclo­addition of Cyclic Azomethine Ylides

(2014) Chun-Jiang Wang et al.   SYNLETT

Dual Catalysis Becomes Diastereodivergent

(2013) Maria Teresa Oliveira et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Iron/Amine-Catalyzed Cascade Process for the Enantioselective Functionalization of Allylic Alcohols

(2013) Adrien Quintard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Amination of Alcohols by the Use of Borrowing Hydrogen Methodology: Cooperative Catalysis by Iridium and a Chiral Phosphoric Acid

(2013) Yao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantio- and Diastereodivergent Dual Catalysis:  -Allylation of Branched Aldehydes

(2013) S. Krautwald et al.   SCIENCE

Combining transition metal catalysis and organocatalysis – an update

(2012) Zhenting Du et al.   CHEMICAL SOCIETY REVIEWS

Enantioselective C-H Crotylation of Primary Alcohols via Hydrohydroxyalkylation of Butadiene

(2012) J. R. Zbieg et al.   SCIENCE

Synergistic catalysis: A powerful synthetic strategy for new reaction development

(2012) Anna E. Allen et al.   Chemical Science

Catalytic Asymmetric Diastereodivergent Deracemization

(2011) Marco Luparia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Ruthenabicyclic Complexes: Precatalysts for Rapid, Enantioselective, and Wide-Scope Hydrogenation of Ketones

(2011) Kazuhiko Matsumura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diastereodivergent Asymmetric Sulfa-Michael Additions of α-Branched Enones using a Single Chiral Organic Catalyst

(2011) Xu Tian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cycle-Specific Organocascade Catalysis: Application to Olefin Hydroamination, Hydro-oxidation, and Amino-oxidation, and to Natural Product Synthesis

(2009) Bryon Simmons et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Combining transition metal catalysis and organocatalysis: a broad new concept for catalysis

(2009) Zhihui Shao et al.   CHEMICAL SOCIETY REVIEWS

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

Linking Structural Dynamics and Functional Diversity in Asymmetric Catalysis

(2009) Akihiro Nojiri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Diastereoselective Switchable Enantioselective Mannich Reaction of Glycine Derivatives with Imines

(2008) Xiao-Xia Yan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY