Impact of environmental toxicants exposure on gut-brain axis in Parkinson disease

The association of enteric neuropathy with gut phenotypes in acute and progressive models of Parkinson’s disease

(2021) Rachel M. McQuade et al.   Scientific Reports

Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates

(2020) Marie-Laure Arotcarena et al.   BRAIN

Gut-brain axis and the spread of α-synuclein pathology: vagal highway or dead end?

(2019) David P. Breen et al.   MOVEMENT DISORDERS

Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease

(2019) Sangjune Kim et al.   NEURON

Initiation of Parkinson’s disease from gut to brain by δ-secretase

(2019) Eun Hee Ahn et al.   CELL RESEARCH

Genetic modifiers of risk and age at onset in GBA associated Parkinson’s disease and Lewy body dementia

(2019) Cornelis Blauwendraat et al.   BRAIN

Early signs of colonic inflammation, intestinal dysfunction, and olfactory impairments in the rotenone-induced mouse model of Parkinson’s disease

(2018) Lívia H. Morais et al.   BEHAVIOURAL PHARMACOLOGY

Parkinson’s disease from the gut

(2018) Rodger A. Liddle   BRAIN RESEARCH

A neuroscience perspective of the gut theory of Parkinson's disease

(2018) Lisa M. Smith et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Awareness and current knowledge of Parkinson disease: A Neurodegenerative disorder

(2018) Asmat Ullah Khan et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve

(2018) Norihito Uemura et al.   Molecular Neurodegeneration

Treatment of autonomic dysfunction in Parkinson disease and other synucleinopathies

(2018) Jose-Alberto Palma et al.   MOVEMENT DISORDERS

Longitudinal Analysis of Fecal Microbiome and Pathologic Processes in a Rotenone Induced Mice Model of Parkinson’s Disease

(2018) Xiaodong Yang et al.   Frontiers in Aging Neuroscience

Parkinson’s Disease: Biomarkers, Treatment, and Risk Factors

(2018) Fatemeh N. Emamzadeh et al.   Frontiers in Neuroscience

A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci

(2017) Diana Chang et al.   NATURE GENETICS

Non-motor features of Parkinson disease

(2017) Anthony H. V. Schapira et al.   NATURE REVIEWS NEUROSCIENCE

Selective neuronal vulnerability in Parkinson disease

(2017) D. James Surmeier et al.   NATURE REVIEWS NEUROSCIENCE

Vagotomy and Parkinson disease

(2017) Bojing Liu et al.   NEUROLOGY

The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy

(2017) Phillip A. Engen et al.   Journal of Parkinsons Disease

Neuropathological Staging of Brain Pathology in Sporadic Parkinson’s disease: Separating the Wheat from the Chaff

(2017) Heiko Braak et al.   Journal of Parkinsons Disease

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

Changes in the sympathetic innervation of the gut in rotenone treated mice as possible early biomarker for Parkinson’s disease

(2016) Mike Arnhold et al.   CLINICAL AUTONOMIC RESEARCH

Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans

(2016) Shu G. Chen et al.   Scientific Reports

Vagotomy and subsequent risk of Parkinson's disease

(2015) Elisabeth Svensson et al.   ANNALS OF NEUROLOGY

Gastrointestinal dysfunction in Parkinson's disease

(2015) Alfonso Fasano et al.   LANCET NEUROLOGY

The role of ATP13A2 in Parkinson's disease: Clinical phenotypes and molecular mechanisms

(2015) Jin-Sung Park et al.   MOVEMENT DISORDERS

Colonic bacterial composition in Parkinson's disease

(2015) Ali Keshavarzian et al.   MOVEMENT DISORDERS

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Pathogenesis of Parkinson disease—the gut–brain axis and environmental factors

(2015) Lisa Klingelhoefer et al.   Nature Reviews Neurology

An update on the rotenone models of Parkinson's disease: Their ability to reproduce the features of clinical disease and model gene–environment interactions

(2015) Michaela E. Johnson et al.   NEUROTOXICOLOGY

Increased urinary indoxyl sulfate (indican): New insights into gut dysbiosis in Parkinson's disease

(2015) Erica Cassani et al.   PARKINSONISM & RELATED DISORDERS

Brain-gut-microbiota axis in Parkinson's disease

(2015) Agata Mulak   WORLD JOURNAL OF GASTROENTEROLOGY

Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats

(2014) Staffan Holmqvist et al.   ACTA NEUROPATHOLOGICA

Gut microbiota are related to Parkinson's disease and clinical phenotype

(2014) Filip Scheperjans et al.   MOVEMENT DISORDERS

Course of psychiatric symptoms and global cognition in early Parkinson disease

(2014) P. de la Riva et al.   NEUROLOGY

Small intestinal bacterial overgrowth in Parkinson's disease

(2014) Ai Huey Tan et al.   PARKINSONISM & RELATED DISORDERS

Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys

(2013) Ariadna Recasens et al.   ANNALS OF NEUROLOGY

Delayed gastric emptying in Parkinson's disease

(2013) Sarah Marrinan et al.   MOVEMENT DISORDERS

Plastic Fantastic: Schwann Cells and Repair of the Peripheral Nervous System

(2013) Haesun A. Kim et al.   Stem Cells Translational Medicine

A cohort study on diet and the risk of Parkinson's disease: the role of food groups and diet quality

(2012) K. Sääksjärvi et al.   BRITISH JOURNAL OF NUTRITION

The Lewy Body in Parkinson’s Disease and Related Neurodegenerative Disorders

(2012) Koichi Wakabayashi et al.   MOLECULAR NEUROBIOLOGY

Pathological  -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice

(2012) K. C. Luk et al.   SCIENCE

Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice

(2012) Francisco Pan-Montojo et al.   Scientific Reports

Molecular analysis of the luminal- and mucosal-associated intestinal microbiota in diarrhea-predominant irritable bowel syndrome

(2011) Ian M. Carroll et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Prevalence of Small Intestinal Bacterial Overgrowth in Parkinson's Disease

(2011) Maurizio Gabrielli et al.   MOVEMENT DISORDERS

Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders

(2010) Thomas G. Beach et al.   ACTA NEUROPATHOLOGICA

Neuropathology of sporadic Parkinson disease before the appearance of parkinsonism: preclinical Parkinson disease

(2010) Isidre Ferrer et al.   JOURNAL OF NEURAL TRANSMISSION

Progression of Parkinson's Disease Pathology Is Reproduced by Intragastric Administration of Rotenone in Mice

(2010) Francisco Pan-Montojo et al.   PLoS One

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

(2009) Etienne C Hirsch et al.   LANCET NEUROLOGY

The scientific and clinical basis for the treatment of Parkinson disease (2009)

(2009) C. W. Olanow et al.   NEUROLOGY

Gait and balance disorders in Parkinson's disease: Impaired active braking of the fall of centre of gravity

(2008) Nathalie Chastan et al.   MOVEMENT DISORDERS

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

(2008) Jia-Yi Li et al.   NATURE MEDICINE