Treatment of autonomic dysfunction in Parkinson disease and other synucleinopathies

First symptoms in multiple system atrophy

(2018) Jake H. McKay et al.   CLINICAL AUTONOMIC RESEARCH

The recommendations of a consensus panel for the screening, diagnosis, and treatment of neurogenic orthostatic hypotension and associated supine hypertension

(2017) Christopher H. Gibbons et al.   JOURNAL OF NEUROLOGY

Efficacy of single or combined midodrine and pyridostigmine in orthostatic hypotension

(2017) Jung-Ick Byun et al.   NEUROLOGY

Does deep brain stimulation improve lower urinary tract symptoms in Parkinson's disease?

(2017) Lambertus P. Witte et al.   NEUROUROLOGY AND URODYNAMICS

A practical review of gastrointestinal manifestations in Parkinson's disease

(2017) Andrew Su et al.   PARKINSONISM & RELATED DISORDERS

Pilot cohort study of endoscopic botulinum neurotoxin injection in Parkinson's disease

(2017) George Triadafilopoulos et al.   PARKINSONISM & RELATED DISORDERS

Lower urinary tract symptoms in Parkinson's disease: Prevalence, aetiology and management

(2017) Claire McDonald et al.   PARKINSONISM & RELATED DISORDERS

Recent advances in the treatment of erectile dysfunction

(2017) David F Mobley et al.   POSTGRADUATE MEDICAL JOURNAL

Fludrocortisone Is Associated With a Higher Risk of All‐Cause Hospitalizations Compared With Midodrine in Patients With Orthostatic Hypotension

(2017) Carlos G. Grijalva et al.   Journal of the American Heart Association

Clinical and manometric characteristics of patients with Parkinson's disease and esophageal symptoms

(2017) A. Su et al.   DISEASES OF THE ESOPHAGUS

Pathological α-synuclein in gastrointestinal tissues from prodromal Parkinson disease patients

(2016) Morten Gersel Stokholm et al.   ANNALS OF NEUROLOGY

Changes in the sympathetic innervation of the gut in rotenone treated mice as possible early biomarker for Parkinson’s disease

(2016) Mike Arnhold et al.   CLINICAL AUTONOMIC RESEARCH

The association between symptoms of sexual dysfunction and age at onset in Parkinson’s disease

(2016) Tuba Özcan et al.   CLINICAL AUTONOMIC RESEARCH

Supine hypertension in Parkinson’s disease and multiple system atrophy

(2016) Alessandra Fanciulli et al.   CLINICAL AUTONOMIC RESEARCH

Clinical benefit of midodrine hydrochloride in symptomatic orthostatic hypotension: a phase 4, double-blind, placebo-controlled, randomized, tilt-table study

(2016) William Smith et al.   CLINICAL AUTONOMIC RESEARCH

Meta-analysis of the safety and efficacy of droxidopa for neurogenic orthostatic hypotension

(2016) Ahmed Elgebaly et al.   CLINICAL AUTONOMIC RESEARCH

Efficacy of Servo-Controlled Splanchnic Venous Compression in the Treatment of Orthostatic HypotensionNovelty and Significance

(2016) Luis E. Okamoto et al.   HYPERTENSION

Evaluation and Treatment of Patients With Constipation

(2016) Todd Stern et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

ɑ-Synuclein strains and the variable pathologies of synucleinopathies

(2016) Wouter Peelaerts et al.   JOURNAL OF NEUROCHEMISTRY

Effects of the novel norepinephrine prodrug, droxidopa, on ambulatory blood pressure in patients with neurogenic orthostatic hypotension

(2016) Horacio Kaufmann et al.   Journal of the American Society of Hypertension

Constipation in parkinson's disease: Subjective symptoms, objective markers, and new perspectives

(2016) Karoline Knudsen et al.   MOVEMENT DISORDERS

Prevalence and treatment of LUTS in patients with Parkinson disease or multiple system atrophy

(2016) Teruyuki Ogawa et al.   Nature Reviews Urology

Esophageal dysfunction in different stages of Parkinson's disease

(2016) I. Suttrup et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Probiotics and prebiotic fiber for constipation associated with Parkinson disease

(2016) Michela Barichella et al.   NEUROLOGY

The Impact of Pallidal and Subthalamic Deep Brain Stimulation on Urologic Function in Parkinson's Disease

(2016) Stephen Mock et al.   NEUROMODULATION

Systematic Review of Stimulant and Nonstimulant Laxatives for the Treatment of Functional constipation

(2016) Pierre Paré et al.   Canadian Journal of Gastroenterology and Hepatology

Vagotomy and subsequent risk of Parkinson's disease

(2015) Elisabeth Svensson et al.   ANNALS OF NEUROLOGY

Clinical features and autonomic testing predict survival in multiple system atrophy

(2015) Elizabeth A. Coon et al.   BRAIN

Re-evaluating the glio-centric view of multiple system atrophy by highlighting the neuronal involvement: Figure 1

(2015) Glenda M. Halliday   BRAIN

Expanding the spectrum of neuronal pathology in multiple system atrophy

(2015) Matthew D. Cykowski et al.   BRAIN

Multiple system atrophy: Using clinical pharmacology to reveal pathophysiology

(2015) Jens Jordan et al.   CLINICAL AUTONOMIC RESEARCH

Clinical characteristics of supine hypertension in de novo Parkinson disease

(2015) Tadashi Umehara et al.   CLINICAL AUTONOMIC RESEARCH

Gastric Electric Stimulation for Refractory Gastroparesis: A Prospective Analysis of 151 Patients at a Single Center

(2015) Jason Heckert et al.   DIGESTIVE DISEASES AND SCIENCES

Dysphagia in Parkinson’s Disease

(2015) Inga Suttrup et al.   DYSPHAGIA

Post-operative swallowing in multiple system atrophy

(2015) R. Ueha et al.   EUROPEAN JOURNAL OF NEUROLOGY

Natural history of multiple system atrophy in the USA: a prospective cohort study

(2015) Phillip A Low et al.   LANCET NEUROLOGY

Gastrointestinal dysfunction in Parkinson's disease

(2015) Alfonso Fasano et al.   LANCET NEUROLOGY

Orthostatic Hypotension in Parkinson Disease: How Much You Fall or How Low You Go?

(2015) Jose-Alberto Palma et al.   MOVEMENT DISORDERS

α-Synuclein strains cause distinct synucleinopathies after local and systemic administration

(2015) W. Peelaerts et al.   NATURE

Ghrelin and motilin receptors as drug targets for gastrointestinal disorders

(2015) Gareth J. Sanger et al.   Nature Reviews Gastroenterology & Hepatology

Characterization of gastrointestinal disorders in patients with parkinsonian syndromes

(2015) Hyeyoung Park et al.   PARKINSONISM & RELATED DISORDERS

Randomized, controlled pilot trial of solifenacin succinate for overactive bladder in Parkinson's disease

(2015) Theresa A. Zesiewicz et al.   PARKINSONISM & RELATED DISORDERS

Propagation of prions causing synucleinopathies in cultured cells

(2015) Amanda L. Woerman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

(2015) Stanley B. Prusiner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats

(2014) Staffan Holmqvist et al.   ACTA NEUROPATHOLOGICA

Is ambulatory blood pressure monitoring useful in patients with chronic autonomic failure?

(2014) Lucy Norcliffe-Kaufmann et al.   CLINICAL AUTONOMIC RESEARCH

New pharmacological treatment options for chronic constipation

(2014) Maura Corsetti et al.   EXPERT OPINION ON PHARMACOTHERAPY

Efficacy of Atomoxetine Versus Midodrine for the Treatment of Orthostatic Hypotension in Autonomic Failure

(2014) Claudia E. Ramirez et al.   HYPERTENSION

Nebivolol, But Not Metoprolol, Lowers Blood Pressure in Nitric Oxide–Sensitive Human Hypertension

(2014) Luis E. Okamoto et al.   HYPERTENSION

Safety and tolerability of atomoxetine in treatment of attention deficit hyperactivity disorder in adult patients: An integrated analysis of 15 clinical trials

(2014) Angelo Camporeale et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Lower urinary tract function in dementia with Lewy bodies (DLB)

(2014) Fuyuki Tateno et al.   MOVEMENT DISORDERS

Droxidopa for the Short-Term Treatment of Symptomatic Neurogenic Orthostatic Hypotension in Parkinson's Disease (nOH306B)

(2014) Robert A. Hauser et al.   MOVEMENT DISORDERS

Norepinephrine deficiency in Parkinson's disease: The case for noradrenergic enhancement

(2014) Alberto J. Espay et al.   MOVEMENT DISORDERS

Multiple organ involvement by alpha-synuclein pathology in Lewy body disorders

(2014) Ellen Gelpi et al.   MOVEMENT DISORDERS

Emerging treatments in Neurogastroenterology: relamorelin: a novel gastrocolokinetic synthetic ghrelin agonist

(2014) M. Camilleri et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Droxidopa for neurogenic orthostatic hypotension: A randomized, placebo-controlled, phase 3 trial

(2014) H. Kaufmann et al.   NEUROLOGY

Results of a randomized, double-blind, parallel-group, placebo- and active-controlled, multicenter study of mirabegron, a β3-adrenoceptor agonist, in patients with overactive bladder in Asia

(2014) Hann-Chorng Kuo et al.   NEUROUROLOGY AND URODYNAMICS

Drooling in Parkinson's disease: A review

(2014) Prachaya Srivanitchapoom et al.   PARKINSONISM & RELATED DISORDERS

Exercise hemodynamics in Parkinson's disease and autonomic dysfunction

(2014) David A. Low et al.   PARKINSONISM & RELATED DISORDERS

Treatment effects for dysphagia in Parkinson's disease: A systematic review

(2014) M.R.A. van Hooren et al.   PARKINSONISM & RELATED DISORDERS

Prion-like spreading of pathological α-synuclein in brain

(2013) Masami Masuda-Suzukake et al.   BRAIN

Cerebellar and parkinsonian phenotypes in multiple system atrophy: similarities, differences and survival

(2013) Dusan Roncevic et al.   JOURNAL OF NEURAL TRANSMISSION

Nocturnal hypertension and dysautonomia in patients with Parkinson’s disease: are they related?

(2013) Koldo Berganzo et al.   JOURNAL OF NEUROLOGY

Parkinson Disease Affects Peripheral Sensory Nerves in the Pharynx

(2013) Liancai Mu et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The natural history of multiple system atrophy: a prospective European cohort study

(2013) Gregor K Wenning et al.   LANCET NEUROLOGY

Dysphagia in Parkinson's disease is responsive to levodopa

(2013) James P. Sutton   PARKINSONISM & RELATED DISORDERS

Swallowing and deep brain stimulation in Parkinson's disease: A systematic review

(2013) Michelle S. Troche et al.   PARKINSONISM & RELATED DISORDERS

Autonomic disorders predicting Parkinson's disease

(2013) Jose-Alberto Palma et al.   PARKINSONISM & RELATED DISORDERS

Stimulation transcutanée chronique du nerf tibial dans l’hyperactivité vésicale des syndromes parkinsoniens

(2013) A. Ohannessian et al.   PROGRES EN UROLOGIE

Clinical Guideline: Management of Gastroparesis

(2012) Michael Camilleri et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Subthalamic deep brain stimulation can improve gastric emptying in Parkinson's disease

(2012) E. Arai et al.   BRAIN

Management approaches to hypertension in autonomic failure

(2012) Amy C. Arnold et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Nizatidine Improves Clinical Symptoms and Gastric Emptying in Patients with Functional Dyspepsia Accompanied by Impaired Gastric Emptying

(2012) S. Futagami et al.   DIGESTION

Intraurethral Alprostadil for Erectile Dysfunction

(2012) Pierre Costa et al.   DRUGS

Synergistic Effect of Norepinephrine Transporter Blockade and α-2 Antagonism on Blood Pressure in Autonomic Failure

(2012) Luis E. Okamoto et al.   HYPERTENSION

Is there delayed gastric emptying in patients with multiple system atrophy? An analysis using the 13C-acetate breath test

(2012) Yuji Tanaka et al.   JOURNAL OF NEUROLOGY

Placebo-controlled trial of lubiprostone for constipation associated with Parkinson disease

(2012) W. G. Ondo et al.   NEUROLOGY

Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice

(2012) Francisco Pan-Montojo et al.   Scientific Reports

A Prospective Study of Bowel Movement Frequency and Risk of Parkinson's Disease

(2011) X. Gao et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

A Randomized Placebo-Controlled Phase IIb Trial of A3309, A Bile Acid Transporter Inhibitor, for Chronic Idiopathic Constipation

(2011) William D Chey et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The Orthostatic Hypotension Questionnaire (OHQ): validation of a novel symptom assessment scale

(2011) Horacio Kaufmann et al.   CLINICAL AUTONOMIC RESEARCH

Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome

(2011) Roy Freeman et al.   CLINICAL AUTONOMIC RESEARCH

Neuromuscular Electrical Stimulation Versus Traditional Therapy in Patients with Parkinson’s Disease and Oropharyngeal Dysphagia: Effects on Quality of Life

(2011) B. J. Heijnen et al.   DYSPHAGIA

Developmental abnormalities, blood pressure variability and renal disease in Riley Day syndrome

(2011) L Norcliffe-Kaufmann et al.   JOURNAL OF HUMAN HYPERTENSION

Botulinum Toxin Type A in Patients With Parkinson's Disease and Refractory Overactive Bladder

(2011) Antonella Giannantoni et al.   JOURNAL OF UROLOGY

The Movement Disorder Society Evidence-Based Medicine Review Update: Treatments for the non-motor symptoms of Parkinson's disease

(2011) Klaus Seppi et al.   MOVEMENT DISORDERS

Cardiovascular dysautonomia in Parkinson disease: From pathophysiology to pathogenesis

(2011) Samay Jain et al.   NEUROBIOLOGY OF DISEASE

Behavioral therapy to treat urinary incontinence in Parkinson disease

(2011) C. P. Vaughan et al.   NEUROLOGY

Parkinson disease: The enteric nervous system spills its guts

(2011) P. Derkinderen et al.   NEUROLOGY

Two Randomized Trials of Linaclotide for Chronic Constipation

(2011) Anthony J. Lembo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Botulinum toxin type A for the treatment of gastroparesis in Parkinson’s disease patients

(2011) Ramon A. Gil et al.   PARKINSONISM & RELATED DISORDERS

Prevalence of orthostatic hypotension in Parkinson’s disease: A systematic review and meta-analysis

(2011) Daan C. Velseboer et al.   PARKINSONISM & RELATED DISORDERS

Prevalence of oropharyngeal dysphagia in Parkinson’s disease: A meta-analysis

(2011) J.G. Kalf et al.   PARKINSONISM & RELATED DISORDERS

Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders

(2010) Thomas G. Beach et al.   ACTA NEUROPATHOLOGICA

The osmopressor response to water drinking

(2010) Marcus May et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Neuroanatomical characteristics of the human pre-Bötzinger complex and its involvement in neurodegenerative brainstem diseases

(2010) Stephan W. Schwarzacher et al.   BRAIN

Abnormal cardiac [123I]-meta-iodobenzylguanidine uptake in multiple system atrophy

(2010) Hiroshi Nagayama et al.   MOVEMENT DISORDERS

Glycopyrrolate for sialorrhea in Parkinson disease: A randomized, double-blind, crossover trial

(2010) M. E. L. Arbouw et al.   NEUROLOGY

Use of botulinim toxin-A for the treatment of overactive bladder symptoms in patients with Parkinsons’s disease

(2010) Haluk Kulaksizoglu et al.   PARKINSONISM & RELATED DISORDERS

Gastrointestinal dysfunction in Parkinson’s disease

(2010) Ronald F. Pfeiffer   PARKINSONISM & RELATED DISORDERS

Advantages of Azithromycin Over Erythromycin in Improving the Gastric Emptying Half-Time in Adult Patients With Gastroparesis

(2010) Jean M Larson et al.   Journal of Neurogastroenterology and Motility

The association between orthostatic hypotension and medication use in the British Women's Heart and Health Study

(2009) S. Kamaruzzaman et al.   AGE AND AGEING

A Systematic Review on Intrapyloric Botulinum Toxin Injection for Gastroparesis

(2009) Yu Bai et al.   DIGESTION

Does levodopa improve swallowing dysfunction in Parkinson’s disease patients?

(2009) C. Menezes et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Prevalence and definition of drooling in Parkinson’s disease: a systematic review

(2009) J. G. Kalf et al.   JOURNAL OF NEUROLOGY

Botulinum Toxin A for Overactive Bladder and Detrusor Muscle Overactivity in Patients With Parkinson's Disease and Multiple System Atrophy

(2009) Antonella Giannantoni et al.   JOURNAL OF UROLOGY

Megacolon in multiple system atrophy: Safety concerns related to PEG

(2009) Toshiyuki Tezuka et al.   MOVEMENT DISORDERS

Levosulpiride-induced movement disorders

(2009) Hae-Won Shin et al.   MOVEMENT DISORDERS

Effects of inhibitory rTMS on bladder function in Parkinson's disease patients

(2009) Livia Brusa et al.   MOVEMENT DISORDERS

The laparoscopic implantation of neuroprothesis to the sacral plexus for therapy of neurogenic bladder dysfunctions after failure of percutaneous sacral nerve stimulation

(2009) Marc Possover   NEUROMODULATION

Clinical outcomes of progressive supranuclear palsy and multiple system atrophy

(2008) S. S. O'Sullivan et al.   BRAIN

Living with autonomic failure

(2008) Michael Rocinante   CLINICAL AUTONOMIC RESEARCH

Hepatic Events Associated with Atomoxetine Treatment for??Attention-Deficit??Hyperactivity Disorder

(2008) Mark E Bangs et al.   DRUG SAFETY

Autonomic dysfunction in different subtypes of multiple system atrophy

(2008) Claudia Schmidt et al.   MOVEMENT DISORDERS

Low myocardial MIBG uptake in multiple system atrophy with incidental Lewy body pathology: An autopsy case report

(2008) Hiroshi Nagayama et al.   MOVEMENT DISORDERS

Mesopontine cholinergic neuron involvement in Lewy body dementia and multiple system atrophy

(2008) A. M. Schmeichel et al.   NEUROLOGY

Acute urodynamic effects of percutaneous posterior tibial nerve stimulation on neurogenic detrusor overactivity in patients with Parkinson's disease

(2008) Sibel Canbaz Kabay et al.   NEUROUROLOGY AND URODYNAMICS

Neurogenic Orthostatic Hypotension

(2008) Roy Freeman   NEW ENGLAND JOURNAL OF MEDICINE