Brain-gut-microbiota axis in Parkinson's disease

Gut/brain axis and the microbiota

(2015) Emeran A. Mayer et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatitis C virus infection: a risk factor for Parkinson's disease

(2015) W. Y.-Y. Wu et al.   JOURNAL OF VIRAL HEPATITIS

The relation between α-synuclein and microglia in Parkinson’s disease: Recent developments

(2015) V. Sanchez-Guajardo et al.   NEUROSCIENCE

Alpha-synuclein in peripheral tissues and body fluids as a biomarker for Parkinson's disease - a systematic review

(2014) N. Malek et al.   ACTA NEUROLOGICA SCANDINAVICA

Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats

(2014) Staffan Holmqvist et al.   ACTA NEUROPATHOLOGICA

The role of the vagal pathway and gastric dopamine in the gastroparesis of rats after a 6-hydroxydopamine microinjection in the substantia nigra

(2014) L.-F. Zheng et al.   Acta Physiologica

Compositional and Functional Features of the Gastrointestinal Microbiome and Their Effects on Human Health

(2014) Emily B. Hollister et al.   GASTROENTEROLOGY

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

(2014) Nagendra Singh et al.   IMMUNITY

Smoking Cessation Alters Intestinal Microbiota

(2014) Luc Biedermann et al.   INFLAMMATORY BOWEL DISEASES

Second peak in the distribution of age at onset of ulcerative colitis in relation to smoking cessation

(2014) Haruhiko Takahashi et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

The Gut Microbiome and the Brain

(2014) Leo Galland   JOURNAL OF MEDICINAL FOOD

Enteric GFAP expression and phosphorylation in Parkinson's disease

(2014) Thomas Clairembault et al.   JOURNAL OF NEUROCHEMISTRY

Neurodegeneration by Activation of the Microglial Complement-Phagosome Pathway

(2014) L.-G. Bodea et al.   JOURNAL OF NEUROSCIENCE

M. paratuberculosis and Parkinson’s disease – Is this a trigger

(2014) Coad Thomas Dow   MEDICAL HYPOTHESES

The role of the LRRK2 gene in Parkinsonism

(2014) Jie-Qiong Li et al.   Molecular Neurodegeneration

Gut feelings about smoking and coffee in Parkinson's disease

(2014) Pascal Derkinderen et al.   MOVEMENT DISORDERS

Peripheral alpha-synuclein and Parkinson's disease

(2014) C. Warren Olanow et al.   MOVEMENT DISORDERS

Enteric glial cells: New players in Parkinson's disease?

(2014) Thomas Clairembault et al.   MOVEMENT DISORDERS

The power in numbers: Gut microbiota in Parkinson's disease

(2014) Joaquin A. Vizcarra et al.   MOVEMENT DISORDERS

Gut microbiota are related to Parkinson's disease and clinical phenotype

(2014) Filip Scheperjans et al.   MOVEMENT DISORDERS

Small intestinal bacterial overgrowth in Parkinson's disease

(2014) Ai Huey Tan et al.   PARKINSONISM & RELATED DISORDERS

Alpha synuclein is transported into and out of the brain by the blood–brain barrier

(2014) Yu-Ting Sui et al.   PEPTIDES

Eradication of Helicobacter pylori Infection Improves Levodopa Action, Clinical Symptoms and Quality of Life in Patients with Parkinson's Disease

(2014) Hasriza Hashim et al.   PLoS One

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

Parkin and mitochondrial quality control: toward assembling the puzzle

(2014) Konstanze F. Winklhofer   TRENDS IN CELL BIOLOGY

Microbiota and neurodevelopmental windows: implications for brain disorders

(2014) Yuliya E. Borre et al.   TRENDS IN MOLECULAR MEDICINE

Diet and the development of the human intestinal microbiome

(2014) Noah Voreades et al.   Frontiers in Microbiology

Significantly higher frequency ofHelicobacter suisin patients with idiopathic parkinsonism than in control patients

(2013) C. Blaecher et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

(2013) Elaine Y. Hsiao et al.   CELL

Early recognition of pelvic floor dyssynergia and colorectal assessment in Parkinson's disease associated with bowel dysfunction

(2013) C.-P. Wang et al.   Colorectal Disease

Influence of coffee (Coffea arabica) and galacto-oligosaccharide consumption on intestinal microbiota and the host responses

(2013) Tatsuya Nakayama et al.   FEMS MICROBIOLOGY LETTERS

Mind the gut: secretion of α-synuclein by enteric neurons

(2013) Stefan A. Grathwohl et al.   JOURNAL OF NEUROCHEMISTRY

Motor fluctuations and Helicobacter pylori in Parkinson’s disease

(2013) Karl-Erik Rahne et al.   JOURNAL OF NEUROLOGY

TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson’s disease

(2013) Sruti Rayaprolu et al.   Molecular Neurodegeneration

Alimentary, my dear Watson? The challenges of enteric α-synuclein as a Parkinson's disease biomarker

(2013) Naomi P. Visanji et al.   MOVEMENT DISORDERS

Beyond here be dragons: SIBO in Parkinson's disease

(2013) Ronald Pfeiffer   MOVEMENT DISORDERS

The role of small intestinal bacterial overgrowth in Parkinson's disease

(2013) Alfonso Fasano et al.   MOVEMENT DISORDERS

Progression of intestinal permeability changes and alpha-synuclein expression in a mouse model of Parkinson's disease

(2013) Leo P. Kelly et al.   MOVEMENT DISORDERS

Parkinson's Disease and Alpha Synuclein: Is Parkinson's Disease a Prion-Like Disorder?

(2013) C. Warren Olanow et al.   MOVEMENT DISORDERS

Melancholic microbes: a link between gut microbiota and depression?

(2013) T. G. Dinan et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Alpha-Synuclein Expression in Patients with Parkinson's Disease: A Clinician's Perspective

(2013) Han-Joon Kim   Experimental Neurobiology

Treatment for Helicobacter pylori infection and risk of parkinson’s disease in Denmark

(2012) H. H. Nielsen et al.   EUROPEAN JOURNAL OF NEUROLOGY

Brain-Gut Interactions in Inflammatory Bowel Disease

(2012) Bruno L. Bonaz et al.   GASTROENTEROLOGY

Anorectal Manometric Dysfunctions in Newly Diagnosed, Early-Stage Parkinson's Disease

(2012) Hye Young Sung et al.   Journal of Clinical Neurology

Extragastrointestinal manifestations of Helicobacter pylori infection: Facts or myth? A critical review

(2012) Huck-Joo TAN et al.   Journal of Digestive Diseases

Activity-dependent secretion of alpha-synuclein by enteric neurons

(2012) Sébastien Paillusson et al.   JOURNAL OF NEUROCHEMISTRY

Gastrointestinal manifestations in Parkinson’s disease: prevalence and occurrence before motor symptoms

(2012) Maria G. Cersosimo et al.   JOURNAL OF NEUROLOGY

Expression pattern and localization of alpha-synuclein in the human enteric nervous system

(2012) Martina Böttner et al.   NEUROBIOLOGY OF DISEASE

Colonic inflammation in Parkinson's disease

(2012) David Devos et al.   NEUROBIOLOGY OF DISEASE

Mice overexpressing wild-type human alpha-synuclein display alterations in colonic myenteric ganglia and defecation

(2012) L. Wang et al.   NEUROGASTROENTEROLOGY AND MOTILITY

A comparison between colonic submucosa and mucosa to detect Lewy pathology in Parkinson’s disease

(2012) H. Pouclet et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Rifampicin and Parkinson’s disease

(2012) Wei Bi et al.   NEUROLOGICAL SCIENCES

Beyond α-synuclein transfer: pathology propagation in Parkinson's disease

(2012) Christian Hansen et al.   TRENDS IN MOLECULAR MEDICINE

APOE ϵ4 Increases Risk for Dementia in Pure Synucleinopathies

(2012) Debby Tsuang et al.   JAMA Neurology

Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson’s Disease

(2011) Hui-Ming Gao et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Epidemiology and etiology of Parkinson’s disease: a review of the evidence

(2011) Karin Wirdefeldt et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Treatment approaches of gastrointestinal dysfunction in Parkinson's disease, therapeutical options and future perspectives

(2011) D. Woitalla et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Anorectal dysfunctions in Parkinson's disease

(2011) Joong-Seok Kim et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

View point: Etiology in Parkinson's disease. Dual hit or spreading intoxication

(2011) Heinz Reichmann   JOURNAL OF THE NEUROLOGICAL SCIENCES

Autonomic involvement in Parkinson's disease: Pathology, pathophysiology, clinical features and possible peripheral biomarkers

(2011) Maria G. Cersosimo et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Prevalence of Small Intestinal Bacterial Overgrowth in Parkinson's Disease

(2011) Maurizio Gabrielli et al.   MOVEMENT DISORDERS

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Pathological correlates of gastrointestinal dysfunction in Parkinson's disease

(2011) Maria G. Cersosimo et al.   NEUROBIOLOGY OF DISEASE

Towards Defining a Rigidity-Associated Pathogenic Pathway in Idiopathic Parkinsonism

(2011) R. John Dobbs et al.   Neurodegenerative Diseases

Parallel manifestations of neuropathologies in the enteric and central nervous systems

(2011) G. Natale et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Intake of Japanese and Chinese teas reduces risk of Parkinson’s disease

(2011) Keiko Tanaka et al.   PARKINSONISM & RELATED DISORDERS

Misfolded α-synuclein and toll-like receptors: therapeutic targets for Parkinson's disease

(2011) Dawn Béraud et al.   PARKINSONISM & RELATED DISORDERS

BCG Vaccine-Induced Neuroprotection in a Mouse Model of Parkinson's Disease

(2011) Jing Yong et al.   PLoS One

Increased Intestinal Permeability Correlates with Sigmoid Mucosa alpha-Synuclein Staining and Endotoxin Exposure Markers in Early Parkinson's Disease

(2011) Christopher B. Forsyth et al.   PLoS One

Brain?Gut?Microbe Communication in Health and Disease

(2011) Sue Grenham et al.   Frontiers in Physiology

Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders

(2010) Thomas G. Beach et al.   ACTA NEUROPATHOLOGICA

Metal Emissions and Urban Incident Parkinson Disease: A Community Health Study of Medicare Beneficiaries by Using Geographic Information Systems

(2010) A. W. Willis et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated α-synuclein gene mutations precede central nervous system changes

(2010) Yien-Ming Kuo et al.   HUMAN MOLECULAR GENETICS

Environmental Factors and Parkinson's Disease: A Case-Control Study in Belgrade, Serbia

(2010) Vlajinac D. Hristina et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Ulcerative colitis exacerbates lipopolysaccharide-induced damage to the nigral dopaminergic system: potential risk factor in Parkinson`s disease

(2010) Ruth F. Villarán et al.   JOURNAL OF NEUROCHEMISTRY

Toll-Like Receptors Expression and Signaling in Glia Cells in Neuro-Amyloidogenic Diseases: Towards Future Therapeutic Application

(2010) Dorit Trudler et al.   MEDIATORS OF INFLAMMATION

Real-time visualization of altered gastric motility by magnetic resonance imaging in patients with Parkinson's disease

(2010) Marcus M. Unger et al.   MOVEMENT DISORDERS

Gastrointestinal dysfunction in Parkinson’s disease

(2010) Ronald F. Pfeiffer   PARKINSONISM & RELATED DISORDERS

Colonic Biopsies to Assess the Neuropathology of Parkinson's Disease and Its Relationship with Symptoms

(2010) Thibaud Lebouvier et al.   PLoS One

CpG Demethylation Enhances Alpha-Synuclein Expression and Affects the Pathogenesis of Parkinson's Disease

(2010) Lumine Matsumoto et al.   PLoS One

The second brain and Parkinson’s disease

(2009) Thibaud Lebouvier et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Impact of coffee consumption on the gut microbiota: A human volunteer study

(2009) Muriel Jaquet et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Microbial endocrinology as a basis for improved l-DOPA bioavailability in Parkinson’s patients treated for Helicobacter pylori

(2009) Mark Lyte   MEDICAL HYPOTHESES

Principles and clinical implications of the brain–gut–enteric microbiota axis

(2009) Sang H. Rhee et al.   Nature Reviews Gastroenterology & Hepatology

Chronic rotenone exposure reproduces Parkinson's disease gastrointestinal neuropathology

(2009) Robert E. Drolet et al.   NEUROBIOLOGY OF DISEASE

Abnormal colonic motility in mice overexpressing human wild-type α-synuclein

(2009) Lixin Wang et al.   NEUROREPORT

Neuropathology of non-motor features of Parkinson disease

(2009) Dennis W. Dickson et al.   PARKINSONISM & RELATED DISORDERS

Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegeneration

(2009) H. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neural control of the gastrointestinal tract: Implications for Parkinson disease

(2008) Maria G. Cersosimo et al.   MOVEMENT DISORDERS

Helicobacter pyloriinfection and motor fluctuations in patients with Parkinson's disease

(2008) Won Yong Lee et al.   MOVEMENT DISORDERS

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

(2008) Jia-Yi Li et al.   NATURE MEDICINE

Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease

(2008) Jeffrey H Kordower et al.   NATURE MEDICINE

Parkinson’s disease and the gut: a well known clinical association in need of an effective cure and explanation

(2008) g. natale et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Endotoxin induces a delayed loss of TH-IR neurons in substantia nigra and motor behavioral deficits

(2008) Yuxin Liu et al.   NEUROTOXICOLOGY