Commentary: Assessing the endocrine disrupting effects of chemicals on invertebrates in the European Union

Computational Techniques and Tools for Omics Data Analysis: State-of-the-Art, Challenges, and Future Directions

(2021) Parampreet Kaur et al.   ARCHIVES OF COMPUTATIONAL METHODS IN ENGINEERING

New ways and new hopes for IGR development

(2021) Marek Jindra   JOURNAL OF PESTICIDE SCIENCE

Sex Determination and Differentiation in Decapod and Cladoceran Crustaceans: An Overview of Endocrine Regulation

(2021) Kenji Toyota et al.   Genes

A Crab Is Not a Fish: Unique Aspects of the Crustacean Endocrine System and Considerations for Endocrine Toxicology

(2021) Thomas Knigge et al.   Frontiers in Endocrinology

Highlighting the gaps in hazard and risk assessment of unregulated Endocrine Active Substances in surface waters: retinoids as a European case study

(2021) Barbara Kubickova et al.   Environmental Sciences Europe

Ecosystem services provided by a non-cultured shellfish species: The common cockle Cerastoderma edule

(2020) David N. Carss et al.   MARINE ENVIRONMENTAL RESEARCH

Invertebrates facing environmental contamination by endocrine disruptors: Novel evidences and recent insights

(2020) Virginie Cuvillier-Hot et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

No evidence that vitellogenin protein expression is induced in marine mussels after exposure to an estrogenic chemical

(2020) Laura Emilia Fernández-González et al.   SCIENCE OF THE TOTAL ENVIRONMENT

The dynamics of stem and crown groups

(2020) Graham E. Budd et al.   Science Advances

In Silico Identification of Chemicals Capable of Binding to the Ecdysone Receptor

(2020) Claire L. Mellor et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Comparative Aspects of Structure and Function of Cnidarian Neuropeptides

(2020) Toshio Takahashi   Frontiers in Endocrinology

Endocrine disruption and altered sexual development in aquatic organisms: an invertebrate perspective

(2020) W. J. Langston   JOURNAL OF THE MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM

(MIS)Use of the Adverse Outcome Pathway Concept for Assessing Endocrine Disruption in Nontarget Organisms

(2020) Laurent Lagadic et al.   Integrated Environmental Assessment and Management

Endocrine Disruption in Invertebrates: A Survey of Research Progress

(2020) Alex T. Ford et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

A critical evaluation of some of the recent so-called ‘evidence’ for the involvement of vertebrate-type sex steroids in the reproduction of mollusks

(2020) István Fodor et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Evaluation of a multiplexed, multispecies nuclear receptor assay for chemical hazard assessment

(2020) Keith A. Houck et al.   TOXICOLOGY IN VITRO

When are Adverse Outcome Pathways and Associated Assays “Fit for Purpose” for Regulatory Decision‐Making and Management of Chemicals?

(2019) Katie Coady et al.   Integrated Environmental Assessment and Management

Establishing the relevance of endocrine‐disrupting effects for nontarget vertebrate populations

(2019) Mark Crane et al.   Integrated Environmental Assessment and Management

A restatement of the natural science evidence base on the effects of endocrine disrupting chemicals on wildlife

(2019) H. Charles J. Godfray et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The utility of vitellogenin as a biomarker of estrogenic endocrine disrupting chemicals in molluscs

(2019) Thi Kim Anh Tran et al.   ENVIRONMENTAL POLLUTION

Modeling the Sensitivity of Aquatic Macroinvertebrates to Chemicals Using Traits

(2019) Sanne J. P. Van den Berg et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Adverse Outcome Pathways: Moving from a Scientific Concept to an Internationally Accepted Framework

(2019) Markus Hecker et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Building and Applying Quantitative Adverse Outcome Pathway Models for Chemical Hazard and Risk Assessment

(2019) Edward J. Perkins et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

The juvenile hormone receptor as a target of juvenoid “insect growth regulators”

(2019) Marek Jindra et al.   ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY

Quantitative Predictions for Molecular Initiating Events using 3D Quantitative Structure-Activity Relationships

(2019) Timothy Eric Harry Allen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

OECD approaches and considerations for regulatory evaluation of endocrine disruptors

(2019) Patience Browne et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The future trajectory of adverse outcome pathways: a commentary

(2018) Fiona Sewell et al.   ARCHIVES OF TOXICOLOGY

Research trends in ecosystem services provided by insects

(2018) Jorge Ari Noriega et al.   BASIC AND APPLIED ECOLOGY

Adverse outcome pathway networks II: Network analytics

(2018) Daniel L. Villeneuve et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Adverse outcome pathway networks I: Development and applications

(2018) Dries Knapen et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Is there any value in measuring vertebrate steroids in invertebrates?

(2018) Alexander P. Scott   GENERAL AND COMPARATIVE ENDOCRINOLOGY

The use of omics-based approaches in regulatory toxicology: an alternative approach to assess the no observed transcriptional effect level

(2018) Daniele Quercioli et al.   MICROCHEMICAL JOURNAL

Using 2D Structural Alerts to Define Chemical Categories for Molecular Initiating Events

(2018) Timothy E H Allen et al.   TOXICOLOGICAL SCIENCES

Workshop on acceleration of the validation and regulatory acceptance of alternative methods and implementation of testing strategies

(2018) A.H. Piersma et al.   TOXICOLOGY IN VITRO

Endocrine Disruption: Current approaches for regulatory testing and assessment of plant protection products are fit for purpose

(2018) Peter Day et al.   TOXICOLOGY LETTERS

Evidence for Cross Species Extrapolation of Mammalian-Based High-Throughput Screening Assay Results

(2018) Carlie A. LaLone et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

A global review of the ecosystem services provided by bivalve aquaculture

(2018) Andrew van der Schatte Olivier et al.   Reviews in Aquaculture

Assessing the population relevance of endocrine disrupting effects for non-target vertebrates exposed to plant protection products

(2018) Mark Crane et al.   Integrated Environmental Assessment and Management

Application of Adverse Outcome Pathways to U.S. EPA’s Endocrine Disruptor Screening Program

(2017) Patience Browne et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Ecdysone Receptor Agonism Leading to Lethal Molting Disruption in Arthropods: Review and Adverse Outcome Pathway Development

(2017) You Song et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Quantitative Adverse Outcome Pathways and Their Application to Predictive Toxicology

(2017) Rory B. Conolly et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Practical approaches to adverse outcome pathway development and weight-of-evidence evaluation as illustrated by ecotoxicological case studies

(2017) Kellie A. Fay et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

A framework for predicting impacts on ecosystem services from (sub)organismal responses to chemicals

(2017) Valery E. Forbes et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Comparative luciferase assay for establishing reliable in vitro screening system of juvenile hormone agonists

(2017) Hitoshi Miyakawa et al.   JOURNAL OF APPLIED TOXICOLOGY

Evolution of thyroid hormone signaling in animals: Non-genomic and genomic modes of action

(2017) Elias Taylor et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

On selecting a minimal set of in vitro assays to reliably determine estrogen agonist activity

(2017) Richard S. Judson et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

The Role of Omics in the Application of Adverse Outcome Pathways for Chemical Risk Assessment

(2017) Erica K. Brockmeier et al.   TOXICOLOGICAL SCIENCES

Recommended approaches to the scientific evaluation of ecotoxicological hazards and risks of endocrine-active substances

(2017) Peter Matthiessen et al.   Integrated Environmental Assessment and Management

Current limitations and recommendations to improve testing for the environmental assessment of endocrine active substances

(2017) Katherine K Coady et al.   Integrated Environmental Assessment and Management

Challenges in assigning endocrine-specific modes of action: Recommendations for researchers and regulators

(2017) Ellen M Mihaich et al.   Integrated Environmental Assessment and Management

Cloning retinoid and peroxisome proliferator-activated nuclear receptors of the Pacific oyster and in silico binding to environmental chemicals

(2017) Susanne Vogeler et al.   PLoS One

More than 75 percent decline over 27 years in total flying insect biomass in protected areas

(2017) Caspar A. Hallmann et al.   PLoS One

Scientific principles for the identification of endocrine-disrupting chemicals: a consensus statement

(2016) Roland Solecki et al.   ARCHIVES OF TOXICOLOGY

Assessing the risks of pesticides to threatened and endangered species using population modeling: A critical review and recommendations for future work

(2016) Valery E. Forbes et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Evaluation of the scientific underpinnings for identifying estrogenic chemicals in nonmammalian taxa using mammalian test systems

(2016) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Environmental surveillance and monitoring-The next frontiers for high-throughput toxicology

(2016) Anthony L. Schroeder et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Editor’s Highlight: Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS): A Web-Based Tool for Addressing the Challenges of Cross-Species Extrapolation of Chemical Toxicity

(2016) Carlie A. LaLone et al.   TOXICOLOGICAL SCIENCES

How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology

(2016) Clemens Wittwehr et al.   TOXICOLOGICAL SCIENCES

Comparative sensitivity of the cnidarian Exaiptasia pallida and a standard toxicity test suite: testing whole effluents intended for ocean disposal

(2015) P. L. Howe et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

In Response: Adverse outcome pathways-An industry perspective

(2015) James R Wheeler et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Evaluating aquatic invertebrate vulnerability to insecticides based on intrinsic sensitivity, biological traits, and toxic mode of action

(2015) Andreu Rico et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Early metazoan life: divergence, environment and ecology

(2015) D. H. Erwin   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence

(2015) Richard A. Becker et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Principles of Pharmacology and Toxicology Also Govern Effects of Chemicals on the Endocrine System

(2015) Herman Autrup et al.   TOXICOLOGICAL SCIENCES

How to use mechanistic effect models in environmental risk assessment of pesticides: Case studies and recommendations from the SETAC workshop MODELINK

(2015) Udo Hommen et al.   Integrated Environmental Assessment and Management

A path forward in the debate over health impacts of endocrine disrupting chemicals

(2015) R Thomas Zoeller et al.   Environmental Health

Larval Exposure to the Juvenile Hormone Analog Pyriproxyfen Disrupts Acceptance of and Social Behavior Performance in Adult Honeybees

(2015) Julie Fourrier et al.   PLoS One

Identification of Thyroid Hormones and Functional Characterization of Thyroid Hormone Receptor in the Pacific Oyster Crassostrea gigas Provide Insight into Evolution of the Thyroid Hormone System

(2015) Wen Huang et al.   PLoS One

Defining Molecular Initiating Events in the Adverse Outcome Pathway Framework for Risk Assessment

(2014) Timothy E. H. Allen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Evaluation of yolk protein levels as estrogenic biomarker in bivalves; comparison of the alkali-labile phosphate method (ALP) and a species-specific immunoassay (ELISA)

(2014) Jane E. Morthorst et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Test driving ToxCast: endocrine profiling for 1858 chemicals included in phase II

(2014) Dayne Filer et al.   CURRENT OPINION IN PHARMACOLOGY

To Bind or Not To Bind: The Taxonomic Scope of Nuclear Receptor Mediated Endocrine Disruption in Invertebrate Phyla

(2014) L. Filipe C. Castro et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Application of in silico and in vitro methods in the development of adverse outcome pathway constructs in wildlife

(2014) J. C. Madden et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Leveraging existing data for prioritization of the ecological risks of human and veterinary pharmaceuticals to aquatic organisms

(2014) C. A. LaLone et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Adverse Outcome Pathway (AOP) Development I: Strategies and Principles

(2014) Daniel L. Villeneuve et al.   TOXICOLOGICAL SCIENCES

Adverse Outcome Pathway Development II: Best Practices

(2014) Daniel L. Villeneuve et al.   TOXICOLOGICAL SCIENCES

Ecosystem Services as a Contested Concept: a Synthesis of Critique and Counter-Arguments

(2014) Matthias Schröter et al.   Conservation Letters

Molecular target sequence similarity as a basis for species extrapolation to assess the ecological risk of chemicals with known modes of action

(2013) Carlie A. LaLone et al.   AQUATIC TOXICOLOGY

Vitellogenin is not an appropriate biomarker of feminisation in a Crustacean

(2013) Stephen Short et al.   AQUATIC TOXICOLOGY

Scientifically unfounded precaution drives European Commission’s recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles

(2013) Daniel R. Dietrich et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Development of a chronic, early life-stage sub-lethal toxicity test and recovery assessment for the tropical zooxanthellate sea anemone Aiptasia pulchella

(2013) Pelli L. Howe et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Science and policy on endocrine disrupters must not be mixed: a reply to a “common sense” intervention by toxicology journal editors

(2013) Åke Bergman et al.   Environmental Health

Reverse engineering and identification in systems biology: strategies, perspectives and challenges

(2013) A. F. Villaverde et al.   Journal of the Royal Society Interface

Key scientific issues relevant to the identification and characterisation of endocrine disrupting substances—Report of the Endocrine Disrupters Expert Advisory Group

(2013) Sharon Munn et al.   TOXICOLOGY LETTERS

Update on EPA’s ToxCast Program: Providing High Throughput Decision Support Tools for Chemical Risk Management

(2012) Robert Kavlock et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Using in Vitro High Throughput Screening Assays to Identify Potential Endocrine-Disrupting Chemicals

(2012) Daniel M. Rotroff et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Aiptasia pulchella:a tropical cnidarian representative for laboratory ecotoxicological research

(2012) Pelli Louise Howe et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Do mollusks use vertebrate sex steroids as reproductive hormones? Part I: Critical appraisal of the evidence for the presence, biosynthesis and uptake of steroids

(2012) Alexander P. Scott   STEROIDS

Do mollusks use vertebrate sex steroids as reproductive hormones? II. Critical review of the evidence that steroids have biological effects

(2012) Alexander P. Scott   STEROIDS

Enhanced effects by mixtures of three estrogenic compounds at environmentally relevant levels on development of Chinese rare minnow (Gobiocypris rarus)

(2011) Shiwei Jin et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

The Cambrian Conundrum: Early Divergence and Later Ecological Success in the Early History of Animals

(2011) D. H. Erwin et al.   SCIENCE

Regulation and dysregulation of vitellogenin mRNA accumulation in daphnids (Daphnia magna)

(2010) Bethany R. Hannas et al.   AQUATIC TOXICOLOGY

High-throughput screening and small animal models, where are we?

(2010) Jean Giacomotto et al.   BRITISH JOURNAL OF PHARMACOLOGY

Environmentally sensitive life-cycle traits have low elasticity: implications for theory and practice

(2010) Valery E. Forbes et al.   ECOLOGICAL APPLICATIONS

Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data

(2010) David M. Reif et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

A new method for ranking mode-specific sensitivity of freshwater arthropods to insecticides and its relationship to biological traits

(2010) Mascha N. Rubach et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Reverse engineering adverse outcome pathways

(2010) Edward J. Perkins et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Adverse outcome pathways and ecological risk assessment: Bridging to population-level effects

(2010) Vincent J. Kramer et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Biosynthesis and metabolism of steroids in molluscs

(2010) Denise Fernandes et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Framework for traits-based assessment in ecotoxicology

(2010) Mascha N Rubach et al.   Integrated Environmental Assessment and Management

Integrating Omic Technologies into Aquatic Ecological Risk Assessment and Environmental Monitoring: Hurdles, Achievements, and Future Outlook

(2009) Graham Van Aggelen et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Reverse engineering: the architecture of biological networks

(2008) Mustafa Khammash   BIOTECHNIQUES

Evolutionary Conservation of Human Drug Targets in Organisms used for Environmental Risk Assessments

(2008) Lina Gunnarsson et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

An Assessment of Endocrine Disruption in Mollusks and the Potential for Developing Internationally Standardized Mollusk Life Cycle Test Guidelines

(2008) Peter Matthiessen   Integrated Environmental Assessment and Management

Risks to aquatic organisms posed by human pharmaceutical use

(2007) Mitchell S. Kostich et al.   SCIENCE OF THE TOTAL ENVIRONMENT