Roles of zinc-binding domain of bacterial RNA polymerase in transcription

Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states

(2021) Mathias Girbig et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genome-scale analyses of transcriptional start sites in Mycobacterium marinum under normoxic and hypoxic conditions

(2021) Shaojia Huang et al.   BMC GENOMICS

Structural visualization of transcription activated by a multidrug-sensing MerR family regulator

(2021) Yang Yang et al.   Nature Communications

Structural basis of copper-efflux-regulator-dependent transcription activation

(2021) Wei Shi et al.   iScience

Transcriptional Pausing as a Mediator of Bacterial Gene Regulation

(2021) Robert Landick   Annual Review of Microbiology

Structure of RNA polymerase II pre-initiation complex at 2.9 Å defines initial DNA opening

(2021) Sandra Schilbach et al.   CELL

Zinc finger proteins: insights into the transcriptional and post transcriptional regulation of immune response

(2021) Gurseen Rakhra et al.   MOLECULAR BIOLOGY REPORTS

Structural basis for activation of Swi2/Snf2 ATPase RapA by RNA polymerase

(2021) Wei Shi et al.   NUCLEIC ACIDS RESEARCH

Drug discovery in the era of cryo-electron microscopy

(2021) Michael J. Robertson et al.   TRENDS IN BIOCHEMICAL SCIENCES

A unique binding between SspA and RNAP β’NTH across low-GC Gram-negative bacteria facilitates SspA-mediated transcription regulation

(2021) Fulin Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structural basis of RNA polymerase recycling by the Swi2/Snf2 family of ATPase RapA in Escherichia coli

(2021) M. Zuhaib Qayyum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the human RNA polymerase I elongation complex

(2021) Dan Zhao et al.   Cell Discovery

The route to transcription initiation determines the mode of transcriptional bursting in E. coli

(2020) Christoph Engl et al.   Nature Communications

Visualization of two architectures in class-II CAP-dependent transcription activation

(2020) Wei Shi et al.   PLOS BIOLOGY

Structural basis of bacterial σ 28 ‐mediated transcription reveals roles of the RNA polymerase zinc‐binding domain

(2020) Wei Shi et al.   EMBO JOURNAL

Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis

(2020) Yong-Heng Huang et al.   MOLECULAR CELL

Revealing secrets of the enigmatic omega subunit of bacterial RNA polymerase

(2020) Juha Kurkela et al.   MOLECULAR MICROBIOLOGY

Structural basis for transcription inhibition by E. coli SspA

(2020) Fulin Wang et al.   NUCLEIC ACIDS RESEARCH

Structural basis of transcription-translation coupling

(2020) Chengyuan Wang et al.   SCIENCE

Structural basis of transcription-translation coupling and collision in bacteria

(2020) Michael William Webster et al.   SCIENCE

UvrD helicase–RNA polymerase interactions are governed by UvrD’s carboxy-terminal Tudor domain

(2020) Ashish A. Kawale et al.   Communications Biology

Pre-termination Transcription Complex: Structure and Function

(2020) Zhitai Hao et al.   MOLECULAR CELL

Basic mechanisms and kinetics of pause-interspersed transcript elongation

(2020) Jin Qian et al.   NUCLEIC ACIDS RESEARCH

Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase ρ

(2020) Nelly Said et al.   SCIENCE

The bacterial multidrug resistance regulator BmrR distorts promoter DNA to activate transcription

(2020) Chengli Fang et al.   Nature Communications

Structural basis for transcription initiation by bacterial ECF σ factors

(2019) Lingting Li et al.   Nature Communications

Structural basis of ECF-σ-factor-dependent transcription initiation

(2019) Wei Lin et al.   Nature Communications

Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor

(2019) Ferdinand Krupp et al.   MOLECULAR CELL

Mechanisms of Bacterial Transcription Termination

(2019) Jeffrey W. Roberts   JOURNAL OF MOLECULAR BIOLOGY

Mechanisms of Transcriptional Pausing in Bacteria

(2019) Jin Young Kang et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural basis for transcription antitermination at bacterial intrinsic terminator

(2019) Linlin You et al.   Nature Communications

Structural basis of Q-dependent transcription antitermination

(2019) Jing Shi et al.   Nature Communications

Structural basis of Q-dependent antitermination

(2019) Zhou Yin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crl activates transcription by stabilizing active conformation of the master stress transcription initiation factor

(2019) Juncao Xu et al.   eLife

Mfd Dynamically Regulates Transcription via a Release and Catch-Up Mechanism

(2018) Tung T. Le et al.   CELL

RNA Polymerase Accommodates a Pause RNA Hairpin by Global Conformational Rearrangements that Prolong Pausing

(2018) Jin Young Kang et al.   MOLECULAR CELL

Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3)

(2018) Wei Lin et al.   MOLECULAR CELL

Structural Basis for NusA Stabilized Transcriptional Pausing

(2018) Xieyang Guo et al.   MOLECULAR CELL

Fidaxomicin jams Mycobacterium tuberculosis RNA polymerase motions needed for initiation via RbpA contacts

(2018) Hande Boyaci et al.   eLife

Transcriptional Responses to ppGpp and DksA

(2018) Richard L. Gourse et al.   Annual Review of Microbiology

Structures of RNA Polymerase Closed and Intermediate Complexes Reveal Mechanisms of DNA Opening and Transcription Initiation

(2017) Robert Glyde et al.   MOLECULAR CELL

Crystal structure ofAquifex aeolicusσNbound to promoter DNA and the structure of σN-holoenzyme

(2017) Elizabeth A. Campbell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis of bacterial transcription activation

(2017) Bin Liu et al.   SCIENCE

Structure of RNA polymerase bound to ribosomal 30S subunit

(2017) Gabriel Demo et al.   eLife

Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA

(2017) Elizabeth A Hubin et al.   eLife

Mechanisms of Bacterial Transcription Termination: All Good Things Must End

(2016) Ananya Ray-Soni et al.   Annual Review of Biochemistry

A novel enrichment strategy reveals unprecedented number of novel transcription start sites at single base resolution in a model prokaryote and the gut microbiome

(2016) Laurence Ettwiller et al.   BMC GENOMICS

Local and global regulation of transcription initiation in bacteria

(2016) Douglas F. Browning et al.   NATURE REVIEWS MICROBIOLOGY

Structural insights into NusG regulating transcription elongation

(2016) Bin Liu et al.   NUCLEIC ACIDS RESEARCH

Structures ofE.coliσS-transcription initiation complexes provide new insights into polymerase mechanism

(2016) Bin Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Two-Way Street: Regulatory Interplay between RNA Polymerase and Nascent RNA Structure

(2016) Jinwei Zhang et al.   TRENDS IN BIOCHEMICAL SCIENCES

Transcription Termination: Variations on Common Themes

(2016) Odil Porrua et al.   TRENDS IN GENETICS

Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble

(2015) Yuhong Zuo et al.   MOLECULAR CELL

Structural basis for transcription reactivation by RapA

(2015) Bin Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of the RNA polymerase- 54 reveal new and conserved regulatory strategies

(2015) Y. Yang et al.   SCIENCE

Global Transcriptional Start Site Mapping Using Differential RNA Sequencing Reveals Novel Antisense RNAs in Escherichia coli

(2014) Maureen K. Thomason et al.   JOURNAL OF BACTERIOLOGY

Mycobacterium RbpA cooperates with the stress-response σB subunit of RNA polymerase in promoter DNA unwinding

(2014) Yangbo Hu et al.   NUCLEIC ACIDS RESEARCH

Identification of Protein Partners in Mycobacteria Using a Single-Step Affinity Purification Method

(2014) Przemysław Płociński et al.   PLoS One

The actinobacterial transcription factor RbpA binds to the principal sigma subunit of RNA polymerase

(2013) Aline Tabib-Salazar et al.   NUCLEIC ACIDS RESEARCH

Genome-wide Mapping of Transcriptional Start Sites Defines an Extensive Leaderless Transcriptome in Mycobacterium tuberculosis

(2013) Teresa Cortes et al.   Cell Reports

Activating Transcription in Bacteria

(2012) David J. Lee et al.   Annual Review of Microbiology

Mycobacterium tuberculosis RbpA protein is a new type of transcriptional activator that stabilizes the σ A -containing RNA polymerase holoenzyme

(2012) Yangbo Hu et al.   NUCLEIC ACIDS RESEARCH

Structure and function of RapA: A bacterial Swi2/Snf2 protein required for RNA polymerase recycling in transcription

(2011) Ding Jun Jin et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Fidaxomicin: A Novel Macrocyclic Antibiotic Approved for Treatment of Clostridium difficile Infection

(2011) A. A. Venugopal et al.   CLINICAL INFECTIOUS DISEASES

Termination and antitermination: RNA polymerase runs a stop sign

(2011) Thomas J. Santangelo et al.   NATURE REVIEWS MICROBIOLOGY

The NusA N-Terminal Domain Is Necessary and Sufficient for Enhancement of Transcriptional Pausing via Interaction with the RNA Exit Channel of RNA Polymerase

(2010) Kook Sun Ha et al.   JOURNAL OF MOLECULAR BIOLOGY

The primary transcriptome of the major human pathogen Helicobacter pylori

(2010) Cynthia M. Sharma et al.   NATURE

Molecular Evolution of Multisubunit RNA Polymerases: Structural Analysis

(2009) William J. Lane et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular Evolution of Multisubunit RNA Polymerases: Sequence Analysis

(2009) William J. Lane et al.   JOURNAL OF MOLECULAR BIOLOGY

Evolution of Complex RNA Polymerases: The Complete Archaeal RNA Polymerase Structure

(2009) Yakov Korkhin et al.   PLOS BIOLOGY

Termination Factor Rho and Its Cofactors NusA and NusG Silence Foreign DNA in E. coli

(2008) C. J. Cardinale et al.   SCIENCE

Structure of RapA, a Swi2/Snf2 Protein that Recycles RNA Polymerase During Transcription

(2008) Gary Shaw et al.   STRUCTURE

RNA polymerase: the vehicle of transcription

(2008) Sergei Borukhov et al.   TRENDS IN MICROBIOLOGY