Visualization of two architectures in class-II CAP-dependent transcription activation

Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding

(2019) Hande Boyaci et al.   NATURE

Structural basis for transcription initiation by bacterial ECF σ factors

(2019) Lingting Li et al.   Nature Communications

Structure of an endosomal signaling GPCR–G protein–β-arrestin megacomplex

(2019) Anthony H. Nguyen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Distinct Mechanisms of Transcription Initiation by RNA Polymerases I and II

(2018) Christoph Engel et al.   Annual Review of Biophysics

Cryo-EM structure ofEscherichia coliσ70RNA polymerase and promoter DNA complex revealed a role of σ non-conserved region during the open complex formation

(2018) Anoop Narayanan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3)

(2018) Wei Lin et al.   MOLECULAR CELL

Structures of Bacterial RNA Polymerase Complexes Reveal the Mechanism of DNA Loading and Transcription Initiation

(2018) Robert Glyde et al.   MOLECULAR CELL

MonoRes: Automatic and Accurate Estimation of Local Resolution for Electron Microscopy Maps

(2018) Jose Luis Vilas et al.   STRUCTURE

Fidaxomicin jams Mycobacterium tuberculosis RNA polymerase motions needed for initiation via RbpA contacts

(2018) Hande Boyaci et al.   eLife

cisTEM, user-friendly software for single-particle image processing

(2018) Timothy Grant et al.   eLife

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition

(2017) Wei Lin et al.   MOLECULAR CELL

Addressing preferred specimen orientation in single-particle cryo-EM through tilting

(2017) Yong Zi Tan et al.   NATURE METHODS

Structural basis of bacterial transcription activation

(2017) Bin Liu et al.   SCIENCE

RNA polymerase motions during promoter melting

(2017) Andrey Feklistov et al.   SCIENCE

Structural insights into NusG regulating transcription elongation

(2016) Bin Liu et al.   NUCLEIC ACIDS RESEARCH

Structures ofE.coliσS-transcription initiation complexes provide new insights into polymerase mechanism

(2016) Bin Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TFE and Spt4/5 open and close the RNA polymerase clamp during the transcription cycle

(2016) Sarah Schulz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis of transcription activation

(2016) Y. Feng et al.   SCIENCE

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structural basis for transcription reactivation by RapA

(2015) Bin Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6

(2015) Timothy Grant et al.   eLife

Transcription Regulation at the Core: Similarities Among Bacterial, Archaeal, and Eukaryotic RNA Polymerases

(2013) Kimberly B. Decker et al.   Annual Review of Microbiology

Structural visualization of key steps in human transcription initiation

(2013) Yuan He et al.   NATURE

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy

(2013) Shaoxia Chen et al.   ULTRAMICROSCOPY

Activating Transcription in Bacteria

(2012) David J. Lee et al.   Annual Review of Microbiology

Opening and Closing of the Bacterial RNA Polymerase Clamp

(2012) A. Chakraborty et al.   SCIENCE

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Three-dimensional EM structure of an intact activator-dependent transcription initiation complex

(2009) B. P. Hudson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA