Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states

Structural basis for RNA polymerase III transcription repression by Maf1

(2020) Matthias K. Vorländer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Assembly of SNAPc, Bdp1, and TBP on the U6 snRNA Gene Promoter in Drosophila melanogaster

(2020) Mun Kyoung Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Effects on prostate cancer cells of targeting RNA polymerase III

(2019) John L Petrie et al.   NUCLEIC ACIDS RESEARCH

Interactive Tree Of Life (iTOL) v4: recent updates and new developments

(2019) Ivica Letunic et al.   NUCLEIC ACIDS RESEARCH

The EMBL-EBI search and sequence analysis tools APIs in 2019

(2019) Fábio Madeira et al.   NUCLEIC ACIDS RESEARCH

How to Recruit the Correct RNA Polymerase? Lessons from snRNA Genes

(2019) Oleksandr Dergai et al.   TRENDS IN GENETICS

Molecular insight into RNA polymerase I promoter recognition and promoter melting

(2019) Yashar Sadian et al.   Nature Communications

Signaling to and from the RNA Polymerase III Transcription and Processing Machinery

(2018) Ian M. Willis et al.   Annual Review of Biochemistry

Regulation of RNA polymerase III transcription during transformation of human IMR90 fibroblasts with defined genetic elements

(2018) Stéphanie Durrieu-Gaillard et al.   CELL CYCLE

A Completely Reimplemented MPI Bioinformatics Toolkit with a New HHpred Server at its Core

(2018) Lukas Zimmermann et al.   JOURNAL OF MOLECULAR BIOLOGY

Generation and validation of homozygous fluorescent knock-in cells using CRISPR–Cas9 genome editing

(2018) Birgit Koch et al.   Nature Protocols

Visualization and analysis of non-covalent contacts using the Protein Contacts Atlas

(2018) Melis Kayikci et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Visualization and analysis of non-covalent contacts using the Protein Contacts Atlas

(2018) Melis Kayikci et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION

(2018) Takanori Nakane et al.   eLife

Structural visualization of RNA polymerase III transcription machineries

(2018) Yan Han et al.   Cell Discovery

Structural basis of RNA polymerase III transcription initiation

(2018) Guillermo Abascal-Palacios et al.   NATURE

Molecular mechanism of promoter opening by RNA polymerase III

(2018) Matthias K. Vorländer et al.   NATURE

Defective RNA polymerase III is negatively regulated by the SUMO-Ubiquitin-Cdc48 pathway

(2018) Zheng Wang et al.   eLife

Bi-allelic POLR3A Loss-of-Function Variants Cause Autosomal-Recessive Wiedemann-Rautenstrauch Syndrome

(2018) Jennifer A. Wambach et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Specific combinations of biallelic POLR3A variants cause Wiedemann-Rautenstrauch syndrome

(2018) Stefano Paolacci et al.   JOURNAL OF MEDICAL GENETICS

UniProt: a worldwide hub of protein knowledge

(2018)   NUCLEIC ACIDS RESEARCH

The Pfam protein families database in 2019

(2018) Sara El-Gebali et al.   NUCLEIC ACIDS RESEARCH

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections

(2017) Benson Ogunjimi et al.   JOURNAL OF CLINICAL INVESTIGATION

RNA polymerase III limits longevity downstream of TORC1

(2017) Danny Filer et al.   NATURE

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

Structure of transcribing mammalian RNA polymerase II

(2016) Carrie Bernecky et al.   NATURE

Near-atomic resolution visualization of human transcription promoter opening

(2016) Yuan He et al.   NATURE

RNA Polymerase III Advances: Structural and tRNA Functional Views

(2016) Aneeshkumar G. Arimbasseri et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mechanism of Transcription Termination by RNA Polymerase III Utilizes a Non-template Strand Sequence-Specific Signal Element

(2015) Aneeshkumar G. Arimbasseri et al.   MOLECULAR CELL

A transcriptional specialist resolved

(2015) Richard J. Maraia et al.   NATURE

Molecular structures of unbound and transcribing RNA polymerase III

(2015) Niklas A. Hoffmann et al.   NATURE

Recessive mutations in POLR1C cause a leukodystrophy by impairing biogenesis of RNA polymerase III

(2015) Isabelle Thiffault et al.   Nature Communications

Archaeal TFEα/β is a hybrid of TFIIE and the RNA polymerase III subcomplex hRPC62/39

(2015) Fabian Blombach et al.   eLife

Clinical spectrum of 4H leukodystrophy caused by POLR3A and POLR3B mutations

(2014) N. I. Wolf et al.   NEUROLOGY

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations

(2014) Peter V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

Solving the RNA polymerase I structural puzzle

(2014) María Moreno-Morcillo et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Gene duplication and neofunctionalization: POLR3G and POLR3GL

(2013) M. Renaud et al.   GENOME RESEARCH

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Conservation between the RNA Polymerase I, II, and III Transcription Initiation Machineries

(2012) Alessandro Vannini et al.   MOLECULAR CELL

Mutations of POLR3A Encoding a Catalytic Subunit of RNA Polymerase Pol III Cause a Recessive Hypomyelinating Leukodystrophy

(2011) Geneviève Bernard et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutations in POLR3A and POLR3B Encoding RNA Polymerase III Subunits Cause an Autosomal-Recessive Hypomyelinating Leukoencephalopathy

(2011) Hirotomo Saitsu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Recessive Mutations in POLR3B, Encoding the Second Largest Subunit of Pol III, Cause a Rare Hypomyelinating Leukodystrophy

(2011) Martine Tétreault et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Structural basis of RNA polymerase II backtracking, arrest and reactivation

(2011) Alan C. M. Cheung et al.   NATURE

Structure-function analysis of hRPC62 provides insights into RNA polymerase III transcription initiation

(2011) Stéphane Lefèvre et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Point mutations in the Rpb9-homologous domain of Rpc11 that impair transcription termination by RNA polymerase III

(2011) J. R. Iben et al.   NUCLEIC ACIDS RESEARCH

The NCBI Taxonomy database

(2011) S. Federhen   NUCLEIC ACIDS RESEARCH

High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice

(2011) Jin Hee Kim et al.   PLoS One

Accelerated Profile HMM Searches

(2011) Sean R. Eddy   PLoS Computational Biology

Mutations in genes encoding subunits of RNA polymerases I and III cause Treacher Collins syndrome

(2010) Johannes G Dauwerse et al.   NATURE GENETICS

Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation

(2010) V. Haurie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA Polymerase III Detects Cytosolic DNA and Induces Type I Interferons through the RIG-I Pathway

(2009) Yu-Hsin Chiu et al.   CELL

The C53/C37 Subcomplex of RNA Polymerase III Lies Near the Active Site and Participates in Promoter Opening

(2009) George A. Kassavetis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III–transcribed RNA intermediate

(2009) Andrea Ablasser et al.   NATURE IMMUNOLOGY

Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution

(2009) D. Wang et al.   SCIENCE