- Home
- Publications
- Publication Search
- Publication Details
Title
Molecular mechanisms of heat shock factor 1 regulation
Authors
Keywords
heat shock response, chaperones, protein homeostasis, transcription regulation, Hsf1, Hsp70
Journal
TRENDS IN BIOCHEMICAL SCIENCES
Volume 47, Issue 3, Pages 218-234
Publisher
Elsevier BV
Online
2021-11-19
DOI
10.1016/j.tibs.2021.10.004
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Heat shock transcription factor 1 is SUMOylated in the activated trimeric state
- (2021) Szymon W. Kmiecik et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The aging proteostasis decline: From nematode to human
- (2021) Anatoly Meller et al. EXPERIMENTAL CELL RESEARCH
- Local translation in nuclear condensate amyloid bodies
- (2021) Phaedra R. Theodoridis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hsf1 activation by proteotoxic stress requires concurrent protein synthesis
- (2021) Blake W. Tye et al. MOLECULAR BIOLOGY OF THE CELL
- The heat shock response and small molecule regulators
- (2021) Margaret K. Kurop et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- HSF1 phase transition mediates stress adaptation and cell fate decisions
- (2020) Giorgio Gaglia et al. NATURE CELL BIOLOGY
- Heat Shock Factor 2 Protects against Proteotoxicity by Maintaining Cell-Cell Adhesion
- (2020) Jenny Joutsen et al. Cell Reports
- Feedback regulation of heat shock factor 1 (Hsf1) activity by Hsp70‐mediated trimer unzipping and dissociation from DNA
- (2020) Szymon W Kmiecik et al. EMBO JOURNAL
- Transient intracellular acidification regulates the core transcriptional heat shock response
- (2020) Catherine G Triandafillou et al. eLife
- Subcellular localization of the J-protein Sis1 regulates the heat shock response
- (2020) Zoë A. Feder et al. JOURNAL OF CELL BIOLOGY
- The ABL2 kinase regulates an HSF1-dependent transcriptional program required for lung adenocarcinoma brain metastasis
- (2020) Jacob P. Hoj et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting therapy-resistant prostate cancer via a direct inhibitor of the human heat shock transcription factor 1
- (2020) Bushu Dong et al. Science Translational Medicine
- Sis1 potentiates the stress response to protein aggregation and elevated temperature
- (2020) Courtney L. Klaips et al. Nature Communications
- Heat Shock Factor 1 Drives Intergenic Association of Its Target Gene Loci upon Heat Shock
- (2019) Surabhi Chowdhary et al. Cell Reports
- Functional Modules of the Proteostasis Network
- (2019) Gopal G. Jayaraj et al. Cold Spring Harbor Perspectives in Biology
- Regulation of the Hsf1-dependent transcriptome via conserved bipartite contacts with Hsp70 promotes survival in yeast
- (2019) Sara Peffer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cytoplasmic protein misfolding titrates Hsp70 to activate nuclear Hsf1
- (2019) Anna E Masser et al. eLife
- Heat-Shock Proteins in Neuroinflammation
- (2019) Brigitta Dukay et al. Frontiers in Pharmacology
- HSF1-Mediated Control of Cellular Energy Metabolism and mTORC1 Activation Drive Acute T-Cell Lymphoblastic Leukemia Progression
- (2019) Binnur Eroglu et al. MOLECULAR CANCER RESEARCH
- Inhibiting Heat Shock Factor 1 in Cancer: A Unique Therapeutic Opportunity
- (2019) Bushu Dong et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Rational design and screening of peptide-based inhibitors of heat shock factor 1 (HSF1)
- (2018) Xu Ran et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Molecular mechanisms driving transcriptional stress responses
- (2018) Anniina Vihervaara et al. NATURE REVIEWS GENETICS
- UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites
- (2018) Vyacheslav Akimov et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites
- (2018) Vyacheslav Akimov et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation
- (2018) Toshiki Kijima et al. Scientific Reports
- Hsf1 and Hsp70 constitute a two-component feedback loop that regulates the yeast heat shock response
- (2018) Joanna Krakowiak et al. eLife
- NRF2 transcriptionally activates the heat shock factor 1 promoter under oxidative stress and affects survival and migration potential of MCF7 cells
- (2018) Soumyadip Paul et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HSF1 mediated stress response of heavy metals
- (2018) Christoph Steurer et al. PLoS One
- Methylene blue increases the amount of HSF1 through promotion of PKA-mediated increase in HSF1-p300 interaction
- (2017) Chao Huang et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Heat shock transcription factor 1 protects against pressure overload-induced cardiac fibrosis via Smad3
- (2017) Ning Zhou et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- New inhibitor targeting human transcription factor HSF1: effects on the heat shock response and tumor cell survival
- (2017) Nuria Vilaboa et al. NUCLEIC ACIDS RESEARCH
- The heat-shock, or HSF1-mediated proteotoxic stress, response in cancer: from proteomic stability to oncogenesis
- (2017) Chengkai Dai PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Rethinking HSF1 in Stress, Development, and Organismal Health
- (2017) Jian Li et al. TRENDS IN CELL BIOLOGY
- Transcriptional response to stress is pre-wired by promoter and enhancer architecture
- (2017) Anniina Vihervaara et al. Nature Communications
- Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington’s disease
- (2017) Rocio Gomez-Pastor et al. Nature Communications
- Bidirectional interplay of HSF1 degradation and UPR activation promotes tau hyperphosphorylation
- (2017) Eunhee Kim et al. PLoS Genetics
- Adaptation to Stressors by Systemic Protein Amyloidogenesis
- (2016) Timothy E. Audas et al. DEVELOPMENTAL CELL
- Mammalian Heat Shock Response and Mechanisms Underlying Its Genome-wide Transcriptional Regulation
- (2016) Dig B. Mahat et al. MOLECULAR CELL
- Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis
- (2016) Eric J. Solís et al. MOLECULAR CELL
- Structure of human heat-shock transcription factor 1 in complex with DNA
- (2016) Tobias Neudegger et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors
- (2016) Alex M Jaeger et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure of human heat-shock transcription factor 1 in complex with DNA
- (2016) Tobias Neudegger et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors
- (2016) Alex M Jaeger et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Molecular mechanism of thermosensory function of human heat shock transcription factor Hsf1
- (2016) Nikolai Hentze et al. eLife
- Dynamic control of Hsf1 during heat shock by a chaperone switch and phosphorylation
- (2016) Xu Zheng et al. eLife
- Celastrol Protects against Obesity and Metabolic Dysfunction through Activation of a HSF1-PGC1α Transcriptional Axis
- (2015) Xinran Ma et al. Cell Metabolism
- NEDD4-mediated HSF1 degradation underlies α-synucleinopathy
- (2015) Eunhee Kim et al. HUMAN MOLECULAR GENETICS
- Heat Shock RNA 1, Known as a Eukaryotic Temperature-Sensing Noncoding RNA, Is of Bacterial Origin
- (2015) Dongjin Choi et al. JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
- Uncoupling Stress-Inducible Phosphorylation of Heat Shock Factor 1 from Its Activation
- (2015) Marek A. Budzyński et al. MOLECULAR AND CELLULAR BIOLOGY
- Repression of the Heat Shock Response Is a Programmed Event at the Onset of Reproduction
- (2015) Johnathan Labbadia et al. MOLECULAR CELL
- The heat shock response restricts virus infection in Drosophila
- (2015) Sarah H. Merkling et al. Scientific Reports
- Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants
- (2015) Thomas L. Prince et al. PLoS One
- The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy
- (2014) Ruth Scherz-Shouval et al. CELL
- Interplay of Acetyltransferase EP300 and the Proteasome System in Regulating Heat Shock Transcription Factor 1
- (2014) Swasti Raychaudhuri et al. CELL
- Organismal proteostasis: role of cell-nonautonomous regulation and transcellular chaperone signaling
- (2014) P. van Oosten-Hawle et al. GENES & DEVELOPMENT
- Genomic Heat Shock Element Sequences Drive Cooperative Human Heat Shock Factor 1 DNA Binding and Selectivity
- (2014) Alex M. Jaeger et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Proteasome Inhibitor Bortezomib Is a Potent Inducer of Zinc Finger AN1-type Domain 2a Gene Expression
- (2014) Antonio Rossi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dual regulation of SPI1/PU.1 transcription factor by heat shock factor 1 (HSF1) during macrophage differentiation of monocytes
- (2014) G Jego et al. LEUKEMIA
- ATF1 Modulates the Heat Shock Response by Regulating the Stress-Inducible Heat Shock Factor 1 Transcription Complex
- (2014) Ryosuke Takii et al. MOLECULAR AND CELLULAR BIOLOGY
- TRIM28 regulates RNA polymerase II promoter-proximal pausing and pause release
- (2014) Heeyoun Bunch et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A Direct Regulatory Interaction between Chaperonin TRiC and Stress-Responsive Transcription Factor HSF1
- (2014) Daniel W. Neef et al. Cell Reports
- Synergistic Effects of Toxic Elements on Heat Shock Proteins
- (2014) Khalid Mahmood et al. Biomed Research International
- Fever, hyperthermia and the heat shock response
- (2013) Ishwar S. Singh et al. INTERNATIONAL JOURNAL OF HYPERTHERMIA
- Cellular stress response and innate immune signaling: integrating pathways in host defense and inflammation
- (2013) Sujatha Muralidharan et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Genetic Selection for Constitutively Trimerized Human HSF1 Mutants Identifies a Role for Coiled-Coil Motifs in DNA Binding
- (2013) Daniel W. Neef et al. G3-Genes Genomes Genetics
- Identification of a Tissue-Selective Heat Shock Response Regulatory Network
- (2013) Eric Guisbert et al. PLoS Genetics
- HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers
- (2012) Marc L. Mendillo et al. CELL
- Heat Shock Factor Hsf1 Cooperates with ErbB2 (Her2/Neu) Protein to Promote Mammary Tumorigenesis and Metastasis
- (2012) Caixia Xi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The p23 Molecular Chaperone and GCN5 Acetylase Jointly Modulate Protein-DNA Dynamics and Open Chromatin Status
- (2012) Elena Zelin et al. MOLECULAR CELL
- RPA Assists HSF1 Access to Nucleosomal DNA by Recruiting Histone Chaperone FACT
- (2012) Mitsuaki Fujimoto et al. MOLECULAR CELL
- Regulation of HSF1 Function in the Heat Stress Response: Implications in Aging and Disease
- (2011) Julius Anckar et al. Annual Review of Biochemistry
- Heat Shock Transcription Factor 1 Is a Key Determinant of HCC Development by Regulating Hepatic Steatosis and Metabolic Syndrome
- (2011) Xiongjie Jin et al. Cell Metabolism
- Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease
- (2011) John Labbadia et al. JOURNAL OF CLINICAL INVESTIGATION
- KRIBB11 Inhibits HSP70 Synthesis through Inhibition of Heat Shock Factor 1 Function by Impairing the Recruitment of Positive Transcription Elongation Factor b to thehsp70Promoter
- (2010) Young Ju Yoon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Heat shock factors: integrators of cell stress, development and lifespan
- (2010) Malin Åkerfelt et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Nuclear Stress Bodies
- (2010) G. Biamonti et al. Cold Spring Harbor Perspectives in Biology
- Modulation of Heat Shock Transcription Factor 1 as a Therapeutic Target for Small Molecule Intervention in Neurodegenerative Disease
- (2010) Daniel W. Neef et al. PLOS BIOLOGY
- Temporal expression of heat shock genes during cold stress and recovery from chill coma in adult Drosophila melanogaster
- (2009) Hervé Colinet et al. FEBS Journal
- Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1
- (2009) S. D. Westerheide et al. SCIENCE
- A transcription cofactor required for the heat-shock response
- (2008) Danmei Xu et al. EMBO REPORTS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started