Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors

Lysine Deacetylases Regulate the Heat Shock Response Including the Age-Associated Impairment of HSF1

(2015) Elena Zelin et al.   JOURNAL OF MOLECULAR BIOLOGY

Intersecting transcription networks constrain gene regulatory evolution

(2015) Trevor R. Sorrells et al.   NATURE

Proteotoxic stress reprograms the chromatin landscape of SUMO modification

(2015) Anne Seifert et al.   Science Signaling

Multifaceted roles of HSF1 in cancer

(2015) Sufang Jiang et al.   TUMOR BIOLOGY

Mitochondrial SSBP1 protects cells from proteotoxic stresses by potentiating stress-induced HSF1 transcriptional activity

(2015) Ke Tan et al.   Nature Communications

Proteotoxic stress reprograms the chromatin landscape of SUMO modification

(2015) Anne Seifert et al.   Science Signaling

The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy

(2014) Ruth Scherz-Shouval et al.   CELL

Heat shock factor 2 is a stress-responsive mediator of neuronal migration defects in models of fetal alcohol syndrome

(2014) R. El Fatimy et al.   EMBO Molecular Medicine

Genomic Heat Shock Element Sequences Drive Cooperative Human Heat Shock Factor 1 DNA Binding and Selectivity

(2014) Alex M. Jaeger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Proteasome Inhibitor Bortezomib Is a Potent Inducer of Zinc Finger AN1-type Domain 2a Gene Expression

(2014) Antonio Rossi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of HSF2 decreases in mitosis to enable stress-inducible transcription and cell survival

(2014) Alexandra N. Elsing et al.   JOURNAL OF CELL BIOLOGY

Uncovering global SUMOylation signaling networks in a site-specific manner

(2014) Ivo A Hendriks et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis of DNA recognition by PCG2 reveals a novel DNA binding mode for winged helix-turn-helix domains

(2014) Junfeng Liu et al.   NUCLEIC ACIDS RESEARCH

Proteome-Wide Identification of SUMO2 Modification Sites

(2014) T. Tammsalu et al.   Science Signaling

A Direct Regulatory Interaction between Chaperonin TRiC and Stress-Responsive Transcription Factor HSF1

(2014) Daniel W. Neef et al.   Cell Reports

Detecting endogenous SUMO targets in mammalian cells and tissues

(2013) Janina Becker et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Transcriptional response to stress in the dynamic chromatin environment of cycling and mitotic cells

(2013) Anniina Vihervaara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Following Gene Duplication, Paralog Interference Constrains Transcriptional Circuit Evolution

(2013) Christopher R. Baker et al.   SCIENCE

HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers

(2012) Marc L. Mendillo et al.   CELL

A dominant-negative mutation of HSF2 associated with idiopathic azoospermia

(2012) Lisha Mou et al.   HUMAN GENETICS

RPA Assists HSF1 Access to Nucleosomal DNA by Recruiting Histone Chaperone FACT

(2012) Mitsuaki Fujimoto et al.   MOLECULAR CELL

Accurate Prediction of Inducible Transcription Factor Binding Intensities In Vivo

(2012) Michael J. Guertin et al.   PLoS Genetics

Regulation of HSF1 Function in the Heat Stress Response: Implications in Aging and Disease

(2011) Julius Anckar et al.   Annual Review of Biochemistry

Heat shock factor 2 is required for maintaining proteostasis against febrile-range thermal stress and polyglutamine aggregation

(2011) Toyohide Shinkawa et al.   MOLECULAR BIOLOGY OF THE CELL

Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases

(2011) Daniel W. Neef et al.   NATURE REVIEWS DRUG DISCOVERY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The heat shock factor family and adaptation to proteotoxic stress

(2010) Mitsuaki Fujimoto et al.   FEBS Journal

Anaphase-Promoting Complex/Cyclosome Participates in the Acute Response to Protein-Damaging Stress

(2010) J. K. Ahlskog et al.   MOLECULAR AND CELLULAR BIOLOGY

The evolution of gene duplications: classifying and distinguishing between models

(2010) Hideki Innan et al.   NATURE REVIEWS GENETICS

Heat shock factors: integrators of cell stress, development and lifespan

(2010) Malin Åkerfelt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids

(2010) H. Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Structural Basis for DNA Strand Separation by the Unconventional Winged-Helix Domain of RecQ Helicase WRN

(2010) Ken Kitano et al.   STRUCTURE

Modulation of Heat Shock Transcription Factor 1 as a Therapeutic Target for Small Molecule Intervention in Neurodegenerative Disease

(2010) Daniel W. Neef et al.   PLOS BIOLOGY

Inhibiting the transcription factor HSF1 as an anticancer strategy

(2009) Luke Whitesell et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The Shock of Aging: Molecular Chaperones and the Heat Shock Response in Longevity and Aging – A Mini-Review

(2009) Stuart K. Calderwood et al.   GERONTOLOGY

Heterotrimerization of Heat-Shock Factors 1 and 2 Provides a Transcriptional Switch in Response to Distinct Stimuli

(2009) Anton Sandqvist et al.   MOLECULAR BIOLOGY OF THE CELL

Interaction of HSF1 and HSF2 with the Hspa1b Promoter in Mouse Epididymal Spermatozoa1

(2008) Donald C. Wilkerson et al.   BIOLOGY OF REPRODUCTION

Molecular Basis for SUMOylation-dependent Regulation of DNA Binding Activity of Heat Shock Factor 2

(2008) Yukihiro Tateishi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Promoter ChIP-chip analysis in mouse testis reveals Y chromosome occupancy by HSF2

(2008) M. Akerfelt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA