Molecular mechanism of thermosensory function of human heat shock transcription factor Hsf1

Structure of human heat-shock transcription factor 1 in complex with DNA

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Structure of human heat-shock transcription factor 1 in complex with DNA

(2016) Tobias Neudegger et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Uncoupling Stress-Inducible Phosphorylation of Heat Shock Factor 1 from Its Activation

(2015) Marek A. Budzyński et al.   MOLECULAR AND CELLULAR BIOLOGY

The I-TASSER Suite: protein structure and function prediction

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I-TASSER server: new development for protein structure and function predictions

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Glucocorticoid Receptor Function Regulated by Coordinated Action of the Hsp90 and Hsp70 Chaperone Cycles

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Interplay of Acetyltransferase EP300 and the Proteasome System in Regulating Heat Shock Transcription Factor 1

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HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models

(2014) Luke Whitesell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Direct Regulatory Interaction between Chaperonin TRiC and Stress-Responsive Transcription Factor HSF1

(2014) Daniel W. Neef et al.   Cell Reports

Heat shock protein 90 (HSP90) inhibitors activate the heat shock factor 1 (HSF1) stress response pathway and improve glucose regulation in diabetic mice

(2012) Jee-Hyung Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Comparative Proteomic Analysis of Eleven Common Cell Lines Reveals Ubiquitous but Varying Expression of Most Proteins

(2012) Tamar Geiger et al.   MOLECULAR & CELLULAR PROTEOMICS

Regulation of HSF1 Function in the Heat Stress Response: Implications in Aging and Disease

(2011) Julius Anckar et al.   Annual Review of Biochemistry

Neuronal circuitry regulates the response of Caenorhabditis elegans to misfolded proteins

(2011) V. Prahlad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The kinetic parameters and energy cost of the Hsp70 chaperone as a polypeptide unfoldase

(2010) Sandeep K Sharma et al.   Nature Chemical Biology

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

Spatially and kinetically resolved changes in the conformational dynamics of the Hsp90 chaperone machine

(2009) Christian Graf et al.   EMBO JOURNAL

Heat shock protein 27 is involved in SUMO-2/3 modification of heat shock factor 1 and thereby modulates the transcription factor activity

(2009) M Brunet Simioni et al.   ONCOGENE

Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1

(2009) S. D. Westerheide et al.   SCIENCE

Two Distinct Disulfide Bonds Formed in Human Heat Shock Transcription Factor 1 Act in Opposition To Regulate Its DNA Binding Activity†

(2008) Ming Lu et al.   BIOCHEMISTRY

I-TASSER server for protein 3D structure prediction

(2008) Yang Zhang   BMC BIOINFORMATICS

Dual Targeting of HSC70 and HSP72 Inhibits HSP90 Function and Induces Tumor-Specific Apoptosis

(2008) Marissa V. Powers et al.   CANCER CELL

Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging

(2008) R. I. Morimoto   GENES & DEVELOPMENT

Convergence of Molecular, Modeling, and Systems Approaches for an Understanding of the Escherichia coli Heat Shock Response

(2008) E. Guisbert et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Molecular Basis for Regulation of the Heat Shock Transcription Factor σ32 by the DnaK and DnaJ Chaperones

(2008) Fernanda Rodriguez et al.   MOLECULAR CELL

Regulation of the Cellular Heat Shock Response in Caenorhabditis elegans by Thermosensory Neurons

(2008) V. Prahlad et al.   SCIENCE