Heat Shock Factor Hsf1 Cooperates with ErbB2 (Her2/Neu) Protein to Promote Mammary Tumorigenesis and Metastasis

Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression

(2012) Ramona Schulz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Heat Shock Transcription Factor Hsf1 Is Involved in Tumor Progression via Regulation of Hypoxia-Inducible Factor 1 and RNA-Binding Protein HuR

(2012) V. L. Gabai et al.   MOLECULAR AND CELLULAR BIOLOGY

Outgrowth of single oncogene-expressing cells from suppressive epithelial environments

(2012) Cheuk T. Leung et al.   NATURE

Heat Shock Transcription Factor 1 Is a Key Determinant of HCC Development by Regulating Hepatic Steatosis and Metabolic Syndrome

(2011) Xiongjie Jin et al.   Cell Metabolism

HSP70 decreases receptor-dependent phosphorylation of Smad2 and blocks TGF-β-induced epithelial-mesenchymal transition

(2011) Yihao Li et al.   Journal of Genetics and Genomics

Heat shock protein Hsp72 plays an essential role in Her2-induced mammary tumorigenesis

(2011) L Meng et al.   ONCOGENE

High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer

(2011) S. Santagata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heat shock proteins in breast cancer progression–A suitable case for treatment?

(2010) Stuart K. Calderwood   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Loss of Hsp110 Leads to Age-Dependent Tau Hyperphosphorylation and Early Accumulation of Insoluble Amyloid  

(2010) B. Eroglu et al.   MOLECULAR AND CELLULAR BIOLOGY

ERK2 but Not ERK1 Induces Epithelial-to-Mesenchymal Transformation via DEF Motif-Dependent Signaling Events

(2010) Sejeong Shin et al.   MOLECULAR CELL

Heat shock factors: integrators of cell stress, development and lifespan

(2010) Malin Åkerfelt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis

(2010) L Meng et al.   ONCOGENE

EGFR signaling in breast cancer: Bad to the bone

(2010) John Foley et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Oncogenes and Tumor Suppressor Genes

(2010) E. Y. H. P. Lee et al.   Cold Spring Harbor Perspectives in Biology

Geldanamycin inhibits TGF-β signaling through induction of Hsp70

(2009) Chang-Hyun Yun et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

14-3-3ζ Cooperates with ErbB2 to Promote Ductal Carcinoma In Situ Progression to Invasive Breast Cancer by Inducing Epithelial-Mesenchymal Transition

(2009) Jing Lu et al.   CANCER CELL

Epithelial-mesenchymal transition in cancer development and its clinical significance

(2009) Masaaki Iwatsuki et al.   CANCER SCIENCE

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Heat shock factor 1 deficiency via its downstream target gene αB-crystallin (Hspb5) impairs p53 degradation

(2009) Xiongjie Jin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth

(2009) Y H Zhao et al.   ONCOGENE

SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK

(2008) Y. Okawa et al.   BLOOD

Mammary development in the embryo and adult: a journey of morphogenesis and commitment

(2008) C. J. Watson et al.   DEVELOPMENT

Small heat shock proteins in smooth muscle

(2008) Sonemany Salinthone et al.   PHARMACOLOGY & THERAPEUTICS