Structures of Tetrahymena ’s respiratory chain reveal the diversity of eukaryotic core metabolism

The Mysterious Multitude: Structural Perspective on the Accessory Subunits of Respiratory Complex I

(2022) Abhilash Padavannil et al.   Frontiers in Molecular Biosciences

ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria

(2021) Alexander Mühleip et al.   Nature Communications

Atomic structures of respiratory complex III2, complex IV, and supercomplex III2-IV from vascular plants

(2021) Maria Maldonado et al.   eLife

Structural Mechanism of Transport of Mitochondrial Carriers

(2021) J. J. Ruprecht et al.   Annual Review of Biochemistry

Complexome profile of Toxoplasma gondii mitochondria identifies divergent subunits of respiratory chain complexes including new subunits of cytochrome bc1 complex

(2021) Andrew E. Maclean et al.   PLoS Pathogens

Structure and Mechanism of Respiratory III–IV Supercomplexes in Bioenergetic Membranes

(2021) Peter Brzezinski et al.   CHEMICAL REVIEWS

Composition and stage dynamics of mitochondrial complexes in Plasmodium falciparum

(2021) Felix Evers et al.   Nature Communications

DeepEMhancer: a deep learning solution for cryo-EM volume post-processing

(2021) Ruben Sanchez-Garcia et al.   Communications Biology

Structure and assembly of the mammalian mitochondrial supercomplex CIII2CIV

(2021) Irene Vercellino et al.   NATURE

High-resolution structure and dynamics of mitochondrial complex I—Insights into the proton pumping mechanism

(2021) Kristian Parey et al.   Science Advances

A common coupling mechanism for A-type heme-copper oxidases from bacteria to mitochondria

(2020) Amandine Maréchal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RCC1L (WBSCR16) isoforms coordinate mitochondrial ribosome assembly through their interaction with GTPases

(2020) Aurelio Reyes et al.   PLoS Genetics

On the Detection and Functional Significance of the Protein–Protein Interactions of Mitochondrial Transport Proteins

(2020) Youjun Zhang et al.   Biomolecules

Structure of the dimeric ATP synthase from bovine mitochondria

(2020) Tobias E. Spikes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The coupling mechanism of mammalian respiratory complex I

(2020) Domen Kampjut et al.   SCIENCE

Specific features and assembly of the plant mitochondrial complex I revealed by cryo-EM

(2020) Heddy Soufari et al.   Nature Communications

Type III ATP synthase is a symmetry-deviated dimer that induces membrane curvature through tetramerization

(2020) Rasmus Kock Flygaard et al.   Nature Communications

Atomic structure of a mitochondrial complex I intermediate from vascular plants

(2020) Maria Maldonado et al.   eLife

Non-uniform refinement: adaptive regularization improves single-particle cryo-EM reconstruction

(2020) Ali Punjani et al.   NATURE METHODS

Dimers of mitochondrial ATP synthase induce membrane curvature and self-assemble into rows

(2019) Thorsten B. Blum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of Respiratory Supercomplex I+III2 Reveal Functional and Conformational Crosstalk

(2019) James A. Letts et al.   MOLECULAR CELL

Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix

(2019) Dorothee Liebschner et al.   Acta Crystallographica Section D-Structural Biology

Cryo-EM structure of the spinach cytochrome b6 f complex at 3.6 Å resolution

(2019) Lorna A. Malone et al.   NATURE

Bottom-up structural proteomics: cryoEM of protein complexes enriched from the cellular milieu

(2019) Chi-Min Ho et al.   NATURE METHODS

Structure of a mitochondrial ATP synthase with bound native cardiolipin

(2019) Alexander Mühleip et al.   eLife

High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease

(2019) Kristian Parey et al.   Science Advances

Structure of the intact 14-subunit human cytochrome c oxidase

(2018) Shuai Zong et al.   CELL RESEARCH

Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states

(2018) Ahmed-Noor A. Agip et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Conserved in situ arrangement of complex I and III2in mitochondrial respiratory chain supercomplexes of mammals, yeast, and plants

(2018) Karen M. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane

(2018) Anurag P. Srivastava et al.   SCIENCE

Structure of the Deactive State of Mammalian Respiratory Complex I

(2018) James N. Blaza et al.   STRUCTURE

Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states

(2018) Ahmed-Noor A. Agip et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural Basis of Membrane Protein Chaperoning through the Mitochondrial Intermembrane Space

(2018) Katharina Weinhäupl et al.   CELL

Structure of yeast cytochrome c oxidase in a supercomplex with cytochrome bc1

(2018) Andrew M. Hartley et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Locking loop movement in the ubiquinone pocket of complex I disengages the proton pumps

(2018) Alfredo Cabrera-Orefice et al.   Nature Communications

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

Cryo-EM structure of respiratory complex I at work

(2018) Kristian Parey et al.   eLife

A Bayesian approach to beam-induced motion correction in cryo-EM single-particle analysis

(2018) Jasenko Zivanov et al.   IUCrJ

Human adenine nucleotide translocases physically and functionally interact with respirasomes

(2017) Ya-Wen Lu et al.   MOLECULAR BIOLOGY OF THE CELL

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain

(2017) James A Letts et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structure of human WBSCR16, an RCC1-like protein in mitochondria

(2017) Masako Koyama et al.   PROTEIN SCIENCE

Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain

(2017) James A Letts et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

WBSCR16 Is a Guanine Nucleotide Exchange Factor Important for Mitochondrial Fusion

(2017) Guorui Huang et al.   Cell Reports

Alternative Conformations of Cytochrome c: Structure, Function, and Detection

(2016) Luciana Hannibal et al.   BIOCHEMISTRY

The origin of the supernumerary subunits and assembly factors of complex I: A treasure trove of pathway evolution

(2016) Dei M. Elurbe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Complex structure of cytochrome c –cytochrome c  oxidase reveals a novel protein–protein interaction mode

(2016) Satoru Shimada et al.   EMBO JOURNAL

Characterization of Human and Yeast Mitochondrial Glycine Carriers with Implications for Heme Biosynthesis and Anemia

(2016) Paola Lunetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Accessory subunits are integral for assembly and function of human mitochondrial complex I

(2016) David A. Stroud et al.   NATURE

Helical arrays of U-shaped ATP synthase dimers form tubular cristae in ciliate mitochondria

(2016) Alexander W. Mühleip et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional asymmetry and electron flow in the bovine respirasome

(2016) Joana S Sousa et al.   eLife

Mitochondrial disease genesCOA6,COX6BandSCO2have overlapping roles in COX2 biogenesis

(2015) Alok Ghosh et al.   HUMAN MOLECULAR GENETICS

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Horizontal membrane-intrinsic α-helices in the stator a-subunit of an F-type ATP synthase

(2015) Matteo Allegretti et al.   NATURE

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Electrostatically Driven Second-Sphere Ligand Switch between High and Low Reorganization Energy Forms of Native Cytochrome c

(2013) Damián Alvarez-Paggi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functions of the hydrophilic channels in protonmotive cytochrome c oxidase

(2013) P. R. Rich et al.   Journal of the Royal Society Interface

Assembly factors for the membrane arm of human complex I

(2013) B. Andrews et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

Structural analysis of cytochrome bc1 complexes: Implications to the mechanism of function

(2012) Di Xia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The mitochondrial oxoglutarate carrier: from identification to mechanism

(2012) Magnus Monné et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Structure of the yeast F1Fo-ATP synthase dimer and its role in shaping the mitochondrial cristae

(2012) K. M. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple phosphorylations of cytochrome c oxidase and their functions

(2012) Stefan Helling et al.   PROTEOMICS

The Q cycle of cytochrome bc complexes: A structure perspective

(2011) William A. Cramer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

X-ray structure of the dimeric cytochrome bc1 complex from the soil bacterium Paracoccus denitrificans at 2.7-Å resolution

(2011) Thomas Kleinschroth et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The O2 reduction and proton pumping gate mechanism of bovine heart cytochrome c oxidase

(2011) Shinya Yoshikawa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Molecular Basis of the Functional Divergence of Fatty Acyl-AMP Ligase Biosynthetic Enzymes of Mycobacterium tuberculosis

(2011) Aneesh Goyal et al.   JOURNAL OF MOLECULAR BIOLOGY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

An Electronic Bus Bar Lies in the Core of Cytochrome bc1

(2010) M. Swierczek et al.   SCIENCE

Highly Divergent Mitochondrial ATP Synthase Complexes in Tetrahymena thermophila

(2010) Praveen Balabaskaran Nina et al.   PLOS BIOLOGY

High resolution crystal structure of Paracoccus denitrificans cytochrome c oxidase: New insights into the active site and the proton transfer pathways

(2009) Juergen Koepke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Structure of Complex III with Bound Cytochromecin Reduced State and Definition of a Minimal Core Interface for Electron Transfer

(2008) Sozanne R. N. Solmaz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Functional Requirements for Activity of the Tim9–Tim10 Complex in Mitochondrial Protein Import

(2008) Michael J. Baker et al.   MOLECULAR BIOLOGY OF THE CELL