The coupling mechanism of mammalian respiratory complex I

Oversized ubiquinones as molecular probes for structural dynamics of the ubiquinone reaction site in mitochondrial respiratory complex I

(2020) Shinpei Uno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox-coupled proton pumping drives carbon concentration in the photosynthetic complex I

(2020) Jan M. Schuller et al.   Nature Communications

Water-Gated Proton Transfer Dynamics in Respiratory Complex I

(2020) Max E. Mühlbauer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Software tools for automated transmission electron microscopy

(2019) Martin Schorb et al.   NATURE METHODS

Role of Second Quinone Binding Site in Proton Pumping by Respiratory Complex I

(2019) Outi Haapanen et al.   Frontiers in Chemistry

Mutations in a conserved loop in the PSST subunit of respiratory complex I affect ubiquinone binding and dynamics

(2019) Etienne Galemou Yoga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

A mechanism to prevent production of reactive oxygen species by Escherichia coli respiratory complex I

(2019) Marius Schulte et al.   Nature Communications

Structures of Respiratory Supercomplex I+III2 Reveal Functional and Conformational Crosstalk

(2019) James A. Letts et al.   MOLECULAR CELL

High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease

(2019) Kristian Parey et al.   Science Advances

A modeling and simulation perspective on the mechanism and function of respiratory complex I

(2018) Outi Haapanen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Long-range proton-coupled electron transfer in biological energy conversion: towards mechanistic understanding of respiratory complex I

(2018) Ville R. I. Kaila   Journal of the Royal Society Interface

Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states

(2018) Ahmed-Noor A. Agip et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the Deactive State of Mammalian Respiratory Complex I

(2018) James N. Blaza et al.   STRUCTURE

Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states

(2018) Ahmed-Noor A. Agip et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Redox-coupled quinone dynamics in the respiratory complex I

(2018) Judith Warnau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

Cryo-EM structure of respiratory complex I at work

(2018) Kristian Parey et al.   eLife

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Symmetry-related proton transfer pathways in respiratory complex I

(2017) Andrea Di Luca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of water and protein dynamics in proton pumping by respiratory complex I

(2017) Outi Haapanen et al.   Scientific Reports

Current topics on inhibitors of respiratory complex I

(2016) Masatoshi Murai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Purification of Ovine Respiratory Complex I Results in a Highly Active and Stable Preparation

(2016) James A. Letts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of mammalian respiratory complex I

(2016) Jiapeng Zhu et al.   NATURE

Atomic structure of the entire mammalian mitochondrial complex I

(2016) Karol Fiedorczuk et al.   NATURE

Accessory subunits are integral for assembly and function of human mitochondrial complex I

(2016) David A. Stroud et al.   NATURE

On the appearance of carboxylates in electrostatic potential maps

(2016) Jimin Wang   PROTEIN SCIENCE

Selective Inhibition of Deactivated Mitochondrial Complex I by Biguanides

(2015) Satoshi Matsuzaki et al.   BIOCHEMISTRY

New Perspectives on Proton Pumping in Cellular Respiration

(2015) Mårten Wikström et al.   CHEMICAL REVIEWS

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy

(2015) Benjamin A Barad et al.   NATURE METHODS

A giant molecular proton pump: structure and mechanism of respiratory complex I

(2015) Leonid A. Sazanov   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Redox-induced activation of the proton pump in the respiratory complex I

(2015) Vivek Sharma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic insight from the crystal structure of mitochondrial complex I

(2015) V. Zickermann et al.   SCIENCE

Electrostatics, hydration, and proton transfer dynamics in the membrane domain of respiratory complex I

(2014) V. R. I. Kaila et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Complex I

(2013) Judy Hirst   Annual Review of Biochemistry

Energy Transducing Roles of Antiporter-like Subunits inEscherichia coliNDH-1 with Main Focus on Subunit NuoN (ND2)

(2013) Motoaki Sato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the entire respiratory complex I

(2013) Rozbeh Baradaran et al.   NATURE

Energy-converting respiratory Complex I: On the way to the molecular mechanism of the proton pump

(2012) Marina Verkhovskaya et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Deactive Form of Respiratory Complex I from Mammalian Mitochondria Is a Na+/H+Antiporter

(2012) Philippa G. Roberts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Subunit NuoL for Proton Translocation by Respiratory Complex I

(2011) Stefan Steimle et al.   BIOCHEMISTRY

PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKaPredictions

(2011) Mats H. M. Olsson et al.   Journal of Chemical Theory and Computation

Quantum Electron Tunneling in Respiratory Complex I

(2011) Tomoyuki Hayashi et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Probing the mechanistic role of the long α-helix in subunit L of respiratory Complex I from Escherichia coli by site-directed mutagenesis

(2011) Galina Belevich et al.   MOLECULAR MICROBIOLOGY

Structure of the membrane domain of respiratory complex I

(2011) Rouslan G. Efremov et al.   NATURE

Functional Dissection of the Proton Pumping Modules of Mitochondrial Complex I

(2011) Stefan Dröse et al.   PLOS BIOLOGY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Cyanobacterial NDH-1 complexes: Novel insights and remaining puzzles

(2010) Natalia Battchikova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The Membrane Subunit NuoL(ND5) Is Involved in the Indirect Proton Pumping Mechanism ofEscherichia coliComplex I

(2010) Eiko Nakamaru-Ogiso et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Basis for the Mechanism of Respiratory Complex I

(2009) John M. Berrisford et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Electrostatic Interactions Between FeS Clusters in NADH:Ubiquinone Oxidoreductase (Complex I) from Escherichia coli†

(2008) Liliya Euro et al.   BIOCHEMISTRY

Identification of the Mitochondrial ND3 Subunit as a Structural Component Involved in the Active/Deactive Enzyme Transition of Respiratory Complex I

(2008) Alexander Galkin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Data mining of metal ion environments present in protein structures

(2008) Heping Zheng et al.   JOURNAL OF INORGANIC BIOCHEMISTRY