Eukaryotic tRNA sequences present conserved and amino acid-specific structural signatures

RNA-dependent synthesis of ergosteryl-3β-O-glycine in Ascomycota expands the diversity of steryl-amino acids

(2022) Nathaniel Yakobov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for impaired 5′ processing of a mutant tRNA associated with defects in neuronal homeostasis

(2022) Lien B. Lai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Post-Transcriptional Modifications of Conserved Nucleotides in the T-Loop of tRNA: A Tale of Functional Convergent Evolution

(2021) Martine Roovers et al.   Genes

Hijacking tRNAs From Translation: Regulatory Functions of tRNAs in Mammalian Cell Physiology

(2021) Irem Avcilar-Kucukgoze et al.   Frontiers in Molecular Biosciences

The expanding world of tRNA modifications and their disease relevance

(2021) Tsutomu Suzuki   NATURE REVIEWS MOLECULAR CELL BIOLOGY

tRNAs as a Driving Force of Genome Evolution in Yeast

(2021) Ana Rita Guimarães et al.   Frontiers in Microbiology

tRNAscan-SE 2.0: improved detection and functional classification of transfer RNA genes

(2021) Patricia P Chan et al.   NUCLEIC ACIDS RESEARCH

Bacterial translation machinery for deliberate mistranslation of the genetic code

(2021) Oscar Vargas-Rodriguez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The many faces of RNA-based RNase P, an RNA-world relic

(2021) Hong-Duc Phan et al.   TRENDS IN BIOCHEMICAL SCIENCES

Dynamic changes in tRNA modifications and abundance during T cell activation

(2021) Roni Rak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond

(2020) Ru-Juan Liu et al.   NUCLEIC ACIDS RESEARCH

Unusual tertiary pairs in eukaryotic tRNA-Ala

(2020) Eric Westhof et al.   RNA

Functions of Bacterial tRNA Modifications: From Ubiquity to Diversity

(2020) Valérie de Crécy-Lagard et al.   TRENDS IN MICROBIOLOGY

Structure of the bacterial ribosome at 2 Å resolution

(2020) Zoe L Watson et al.   eLife

Partition of tRNAGly isoacceptors between protein and cell-wall peptidoglycan synthesis in Staphylococcus aureus

(2020) Lauriane Rietmeyer et al.   NUCLEIC ACIDS RESEARCH

The structural characteristics and the substrate recognition properties of RNase ZS1

(2020) Guoqing Peng et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Pathways to disease from natural variations in human cytoplasmic tRNAs

(2019) Jeremy T Lant et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matching tRNA modifications in humans to their known and predicted enzymes

(2019) Valérie de Crécy-Lagard et al.   NUCLEIC ACIDS RESEARCH

Charging the code — tRNA modification complexes

(2019) Rościsław Krutyhołowa et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The multiple flavors of GoU pairs in RNA

(2019) Eric Westhof et al.   JOURNAL OF MOLECULAR RECOGNITION

tRNAviz: explore and visualize tRNA sequence features

(2019) Brian Y Lin et al.   NUCLEIC ACIDS RESEARCH

SPDI: Data Model for Variants and Applications at NCBI

(2019) J Bradley Holmes et al.   BIOINFORMATICS

Control of noncoding RNA production and histone levels by a 5′ tRNA fragment

(2019) Ana Boskovic et al.   GENES & DEVELOPMENT

Predicting transfer RNA gene activity from sequence and genome context

(2019) Bryan P. Thornlow et al.   GENOME RESEARCH

A tRNA's fate is decided at its 3′ end: Collaborative actions of CCA-adding enzyme and RNases involved in tRNA processing and degradation

(2018) Karolin Wellner et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Modifications and functional genomics of human transfer RNA

(2018) Tao Pan   CELL RESEARCH

Dimerization confers increased stability to nucleases in 5′ halves from glycine and glutamic acid tRNAs

(2018) Juan Pablo Tosar et al.   NUCLEIC ACIDS RESEARCH

mRNA Translation Gone Awry: Translation Fidelity and Neurological Disease

(2018) Mridu Kapur et al.   TRENDS IN GENETICS

Transfer RNA-derived fragments and tRNA halves: biogenesis, biological functions and their roles in diseases

(2018) Yijing Shen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Transfer RNA genes experience exceptionally elevated mutation rates

(2018) Bryan P. Thornlow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MODOMICS: a database of RNA modification pathways. 2017 update

(2017) Pietro Boccaletto et al.   NUCLEIC ACIDS RESEARCH

Deciphering the tRNA-dependent lipid aminoacylation systems in bacteria: Novel components and structural advances

(2017) Rachel N. Fields et al.   RNA Biology

Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin

(2017) Moran Shalev-Benami et al.   Nature Communications

Large Conformational Changes of Insertion 3 in Human Glycyl-tRNA Synthetase (hGlyRS) during Catalysis

(2016) Xiangyu Deng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-canonical roles of tRNAs and tRNA mimics in bacterial cell biology

(2016) Assaf Katz et al.   MOLECULAR MICROBIOLOGY

An integrated, structure- and energy-based view of the genetic code

(2016) Henri Grosjean et al.   NUCLEIC ACIDS RESEARCH

Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code

(2016) Alexey Rozov et al.   Nature Communications

Endogenous tRNA-Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement

(2015) Hani Goodarzi et al.   CELL

Eukaryotic tRNAs fingerprint invertebrates vis-à-vis vertebrates

(2015) Sanga Mitra et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Genetic code flexibility in microorganisms: novel mechanisms and impact on physiology

(2015) Jiqiang Ling et al.   NATURE REVIEWS MICROBIOLOGY

GtRNAdb 2.0: an expanded database of transfer RNA genes identified in complete and draft genomes

(2015) Patricia P. Chan et al.   NUCLEIC ACIDS RESEARCH

The molecular mechanism of nuclear transport revealed by atomic-scale measurements

(2015) Loren E Hough et al.   eLife

Reduced Amino Acid Specificity of Mammalian Tyrosyl-tRNA Synthetase Is Associated with Elevated Mistranslation of Tyr Codons

(2014) Medha Raina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The selective tRNA aminoacylation mechanism based on a single G•U pair

(2014) Masahiro Naganuma et al.   NATURE

G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments

(2014) Pavel Ivanov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversity of human tRNA genes from the 1000-genomes project

(2014) Marc Parisien et al.   RNA Biology

Ribosome stalling induced by mutation of a CNS-specific tRNA causes neurodegeneration

(2014) R. Ishimura et al.   SCIENCE

Structural Basis of the Translational Elongation Cycle

(2013) Rebecca M. Voorhees et al.   Annual Review of Biochemistry

Transfer RNA Post-Transcriptional Processing, Turnover, and Subcellular Dynamics in the YeastSaccharomyces cerevisiae

(2013) Anita K. Hopper   GENETICS

Essential nontranslational functions of tRNA synthetases

(2013) Min Guo et al.   Nature Chemical Biology

Molecular Mechanism of Scanning and Start Codon Selection in Eukaryotes

(2011) A. G. Hinnebusch   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Pol III binding in six mammals shows conservation among amino acid isotypes despite divergence among tRNA genes

(2011) Claudia Kutter et al.   NATURE GENETICS

Is the sequence-specific binding of aminoacyl-tRNAs by EF-Tu universal among bacteria?

(2011) J. M. Schrader et al.   NUCLEIC ACIDS RESEARCH

Ribonuclease P

(2011) S. Altman   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Structure of transfer RNAs: similarity and variability

(2011) Richard Giegé et al.   Wiley Interdisciplinary Reviews-RNA

Genomic organization of eukaryotic tRNAs

(2010) Clara Bermudez-Santana et al.   BMC GENOMICS

PHAST and RPHAST: phylogenetic analysis with space/time models

(2010) M. J. Hubisz et al.   BRIEFINGS IN BIOINFORMATICS

tRNA biology charges to the front

(2010) E. M. Phizicky et al.   GENES & DEVELOPMENT

Database resources of the National Center for Biotechnology Information

(2010) E. W. Sayers et al.   NUCLEIC ACIDS RESEARCH

3′ processing of eukaryotic precursor tRNAs

(2010) Richard J. Maraia et al.   Wiley Interdisciplinary Reviews-RNA

Deciphering synonymous codons in the three domains of life: Co-evolution with specific tRNA modification enzymes

(2009) Henri Grosjean et al.   FEBS LETTERS

Eukaryotic initiator tRNA: Finely tuned and ready for action

(2009) Sarah E. Kolitz et al.   FEBS LETTERS

Detection of nonneutral substitution rates on mammalian phylogenies

(2009) K. S. Pollard et al.   GENOME RESEARCH

Dynamic Organization of Aminoacyl-tRNA Synthetase Complexes in the Cytoplasm of Human Cells

(2009) Monika Kaminska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY