The many faces of RNA-based RNase P, an RNA-world relic

Computationally reconstructing cotranscriptional RNA folding from experimental data reveals rearrangement of non-native folding intermediates

(2021) Angela M Yu et al.   MOLECULAR CELL

Protein cofactors and substrate influence Mg2+-dependent structural changes in the catalytic RNA of archaeal RNase P

(2021) Ila A Marathe et al.   NUCLEIC ACIDS RESEARCH

Piece by piece: Building a ribozyme

(2020) Michael W. Gray et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Root of the Tree: The Significance, Evolution, and Origins of the Ribosome

(2020) Jessica C. Bowman et al.   CHEMICAL REVIEWS

Pentatricopeptide repeats of protein-only RNase P use a distinct mode to recognize conserved bases and structural elements of pre-tRNA

(2020) Takamasa Teramoto et al.   NUCLEIC ACIDS RESEARCH

Structural insight into precursor ribosomal RNA processing by ribonuclease MRP

(2020) Pengfei Lan et al.   SCIENCE

Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP

(2020) Anna Perederina et al.   Nature Communications

Alternative Protein Topology-Mediated Evolution of a Catalytic Ribonucleoprotein

(2020) Lien B. Lai et al.   TRENDS IN BIOCHEMICAL SCIENCES

Retrieving functional pathways of biomolecules from single-particle snapshots

(2020) Ali Dashti et al.   Nature Communications

Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase ρ

(2020) Nelly Said et al.   SCIENCE

X-Ray Free-Electron Lasers for the Structure and Dynamics of Macromolecules

(2019) Henry N. Chapman   Annual Review of Biochemistry

The Role of Archaeal Chromatin in Transcription

(2019) Travis J. Sanders et al.   JOURNAL OF MOLECULAR BIOLOGY

Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription

(2019) Rui Xiao et al.   CELL

Cryo-electron microscopy structure of an archaeal ribonuclease P holoenzyme

(2019) Futang Wan et al.   Nature Communications

Biological Insight from Super-Resolution Microscopy: What We Can Learn from Localization-Based Images

(2018) David Baddeley et al.   Annual Review of Biochemistry

La involvement in tRNA and other RNA processing events including differences among yeast and other eukaryotes

(2018) Nathan H. Blewett et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Rpp29 regulates histone H3.3 chromatin assembly through transcriptional mechanisms

(2018) Prashanth Krishna Shastrula et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vitro reconstitution and analysis of eukaryotic RNase P RNPs

(2018) Anna Perederina et al.   NUCLEIC ACIDS RESEARCH

Critical domain interactions for type A RNase P RNA catalysis with and without the specificity domain

(2018) Guanzhong Mao et al.   PLoS One

Reconstitution of 30S ribosomal subunits in vitro using ribosome biogenesis factors

(2018) Daichi Tamaru et al.   RNA

Structural insight into precursor tRNA processing by yeast ribonuclease P

(2018) Pengfei Lan et al.   SCIENCE

Cryo-EM Structure of the Human Ribonuclease P Holoenzyme

(2018) Jian Wu et al.   CELL

Both kinds of RNase P in all domains of life: Surprises galore

(2018) Charles J. Daniels et al.   RNA

A novel double kink-turn module in euryarchaeal RNase P RNAs

(2017) Lien B. Lai et al.   NUCLEIC ACIDS RESEARCH

Minimal and RNA-free RNase P inAquifex aeolicus

(2017) Astrid I. Nickel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chance and necessity in the evolution of RNase P

(2017) Venkat Gopalan et al.   RNA

Roles of RNase P and Its Subunits

(2017) Nayef Jarrous   TRENDS IN GENETICS

RNase P protein subunit Rpp29 represses histone H3.3 nucleosome deposition

(2016) Alyshia Newhart et al.   MOLECULAR BIOLOGY OF THE CELL

Precursors of tRNAs are stabilized by methylguanosine cap structures

(2016) Takayuki Ohira et al.   Nature Chemical Biology

Use of chemical modification and mass spectrometry to identify substrate-contacting sites in proteinaceous RNase P, a tRNA processing enzyme

(2016) Tien-Hao Chen et al.   NUCLEIC ACIDS RESEARCH

tRNA processing defects induce replication stress and Chk2-dependent disruption of piRNA transcription

(2015) A. Molla-Herman et al.   EMBO JOURNAL

Human RNase P ribonucleoprotein is required for formation of initiation complexes of RNA polymerase III

(2015) R. Serruya et al.   NUCLEIC ACIDS RESEARCH

Footprinting analysis of interactions between the largest eukaryotic RNase P/MRP protein Pop1 and RNase P/MRP RNA components

(2015) Robert D. Fagerlund et al.   RNA

Uncovering the Stoichiometry ofPyrococcus furiosusRNase P, a Multi-Subunit Catalytic Ribonucleoprotein Complex, by Surface-Induced Dissociation and Ion Mobility Mass Spectrometry

(2014) Xin Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The L7Ae protein binds to two kink-turns in the Pyrococcus furiosus RNase P RNA

(2014) Stella M. Lai et al.   NUCLEIC ACIDS RESEARCH

RNase MRP Cleaves Pre-tRNASer-Met in the tRNA Maturation Pathway

(2014) Yuichiro Saito et al.   PLoS One

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

Structural Studies of RNase P

(2013) Alfonso Mondragón   Annual Review of Biophysics

Transfer RNA Post-Transcriptional Processing, Turnover, and Subcellular Dynamics in the YeastSaccharomyces cerevisiae

(2013) Anita K. Hopper   GENETICS

Hidden specificity in an apparently nonspecific RNA-binding protein

(2013) Ulf-Peter Guenther et al.   NATURE

Structural insights into protein-only RNase P complexed with tRNA

(2013) Anthony Gobert et al.   Nature Communications

Fidelity of tRNA 5′-maturation: a possible basis for the functional dependence of archaeal and eukaryal RNase P on multiple protein cofactors

(2012) Wen-Yi Chen et al.   NUCLEIC ACIDS RESEARCH

Modeling the Thermoproteaceae RNase P RNA

(2012) Patricia P. Chan et al.   RNA Biology

Functional Coupling between a Distal Interaction and the Cleavage Site in Bacterial RNase-P-RNA-Mediated Cleavage

(2011) Shiying Wu et al.   JOURNAL OF MOLECULAR BIOLOGY

Cooperative RNP Assembly: Complementary Rescue of Structural Defects by Protein and RNA Subunits of Archaeal RNase P

(2011) Wen-Yi Chen et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of a bacterial ribonuclease P holoenzyme in complex with tRNA

(2010) Nicholas J. Reiter et al.   NATURE

Cleavage of model substrates by archaeal RNase P: role of protein cofactors in cleavage-site selection

(2010) Sylvie Sinapah et al.   NUCLEIC ACIDS RESEARCH

Dissecting functional cooperation among protein subunits in archaeal RNase P, a catalytic ribonucleoprotein complex

(2010) Wen-Yi Chen et al.   NUCLEIC ACIDS RESEARCH

Heterodimerization of the human RNase P/MRP subunits Rpp20 and Rpp25 is a prerequisite for interaction with the P3 arm of RNase MRP RNA

(2010) Katherine L. D. Hands-Taylor et al.   NUCLEIC ACIDS RESEARCH

Ribosomal protein L7Ae is a subunit of archaeal RNase P

(2010) I.-M. Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of a minimal form of RNase P in Pyrobaculum

(2010) L. B. Lai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The RNase P family

(2010) J. Christopher Ellis et al.   RNA Biology

Of proteins and RNA: The RNase P/MRP family

(2010) O. Esakova et al.   RNA

Irremediable Complexity?

(2010) M. W. Gray et al.   SCIENCE

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Unexpected diversity of RNase P, an ancient tRNA processing enzyme: Challenges and prospects

(2009) Lien B. Lai et al.   FEBS LETTERS

RNase P RNA-mediated cleavage

(2009) Leif A. Kirsebom et al.   IUBMB LIFE

Solution Structure of an Archaeal RNase P Binary Protein Complex: Formation of the 30-kDa Complex between Pyrococcus furiosus RPP21 and RPP29 Is Accompanied by Coupled Protein Folding and Highlights Critical Features for Protein–Protein and Protein–RNA Interactions

(2009) Yiren Xu et al.   JOURNAL OF MOLECULAR BIOLOGY

Conformational change in the Bacillus subtilis RNase P holoenzyme-pre-tRNA complex enhances substrate affinity and limits cleavage rate

(2009) J. Hsieh et al.   RNA

RNase P without RNA: Identification and Functional Reconstitution of the Human Mitochondrial tRNA Processing Enzyme

(2008) Johann Holzmann et al.   CELL

Minor changes largely restore catalytic activity of archaeal RNase P RNA from Methanothermobacter thermoautotrophicus

(2008) Dan Li et al.   NUCLEIC ACIDS RESEARCH

Studies on Methanocaldococcus jannaschii RNase P reveal insights into the roles of RNA and protein cofactors in RNase P catalysis

(2008) D. K. Pulukkunat et al.   NUCLEIC ACIDS RESEARCH

Function and Assembly of a Chromatin-Associated RNase P that Is Required for Efficient Transcription by RNA Polymerase I

(2008) Robert Reiner et al.   PLoS One