Genetic code flexibility in microorganisms: novel mechanisms and impact on physiology

A synthetic tRNA for EF-Tu mediated selenocysteine incorporationin vivoandin vitro

(2015) Corwin Miller et al.   FEBS LETTERS

Codon Bias as a Means to Fine-Tune Gene Expression

(2015) Tessa E.F. Quax et al.   MOLECULAR CELL

Recoded organisms engineered to depend on synthetic amino acids

(2015) Alexis J. Rovner et al.   NATURE

Biocontainment of genetically modified organisms by synthetic protein design

(2015) Daniel J. Mandell et al.   NATURE

Protein mistranslation protects bacteria against oxidative stress

(2015) Yongqiang Fan et al.   NUCLEIC ACIDS RESEARCH

Highly reproductive Escherichia coli cells with no specific assignment to the UAG codon

(2015) Takahito Mukai et al.   Scientific Reports

Expanding and Reprogramming the Genetic Code of Cells and Animals

(2014) Jason W. Chin   Annual Review of Biochemistry

Comparative genomics highlights the unique biology of Methanomassiliicoccales, a Thermoplasmatales-related seventh order of methanogenic archaea that encodes pyrrolysine

(2014) Guillaume Borrel et al.   BMC GENOMICS

Expanded Genetic Code Technologies for Incorporating Modified Lysine at Multiple Sites

(2014) Tatsuo Yanagisawa et al.   CHEMBIOCHEM

Natural and synthetic selenoproteins

(2014) Norman Metanis et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Evolving tRNASec for Efficient Canonical Incorporation of Selenocysteine

(2014) Ross Thyer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bacteriophages use an expanded genetic code on evolutionary paths to higher fitness

(2014) Michael J Hammerling et al.   Nature Chemical Biology

Mechanism of oxidant-induced mistranslation by threonyl-tRNA synthetase

(2014) Jiang Wu et al.   NUCLEIC ACIDS RESEARCH

Engineering the elongation factor Tu for efficient selenoprotein synthesis

(2014) Ken-ichi Haruna et al.   NUCLEIC ACIDS RESEARCH

Revealing the amino acid composition of proteins within an expanded genetic code

(2014) Hans R. Aerni et al.   NUCLEIC ACIDS RESEARCH

Reducing the genetic code induces massive rearrangement of the proteome

(2014) Patrick O’Donoghue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polyspecific pyrrolysyl-tRNA synthetases from directed evolution

(2014) Li-Tao Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A nonpyrrolysine member of the widely distributed trimethylamine methyltransferase family is a glycine betaine methyltransferase

(2014) T. Ticak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance

(2014) B. Javid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stop codon reassignments in the wild

(2014) N. N. Ivanova et al.   SCIENCE

Total Synthesis of a Functional Designer Eukaryotic Chromosome

(2014) N. Annaluru et al.   SCIENCE

Recoding the Genetic Code with Selenocysteine

(2013) Markus J. Bröcker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Adaptive Translation as a Mechanism of Stress Response and Adaptation

(2013) Tao Pan   Annual Review of Genetics

Selenocysteine Confers Resistance to Inactivation by Oxidation in Thioredoxin Reductase: Comparison of Selenium and Sulfur Enzymes

(2013) Gregg W. Snider et al.   BIOCHEMISTRY

Identification of nucleotides and amino acids that mediate the interaction between ribosomal protein L30 and the SECIS element

(2013) Abby L Bifano et al.   BMC MOLECULAR BIOLOGY

The path of lysine to pyrrolysine

(2013) Joseph A Krzycki   CURRENT OPINION IN CHEMICAL BIOLOGY

The thioredoxin antioxidant system

(2013) Jun Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE

A fable of too much too fast

(2013) Jennifer M. Hurley et al.   NATURE

Non-optimal codon usage affects expression, structure and function of clock protein FRQ

(2013) Mian Zhou et al.   NATURE

Non-optimal codon usage is a mechanism to achieve circadian clock conditionality

(2013) Yao Xu et al.   NATURE

Upgrading protein synthesis for synthetic biology

(2013) Patrick O'Donoghue et al.   Nature Chemical Biology

Natural reassignment of CUU and CUA sense codons to alanine in Ashbya mitochondria

(2013) Jiqiang Ling et al.   NUCLEIC ACIDS RESEARCH

Wobble decoding by the Escherichia coli selenocysteine insertion machinery

(2013) J. Xu et al.   NUCLEIC ACIDS RESEARCH

Sounds of silence: synonymous nucleotides as a key to biological regulation and complexity

(2013) S. A. Shabalina et al.   NUCLEIC ACIDS RESEARCH

Environmental perturbations lift the degeneracy of the genetic code to regulate protein levels in bacteria

(2013) A. R. Subramaniam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expanded use of sense codons is regulated by modified cytidines in tRNA

(2013) W. A. Cantara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversion of a fungal genetic code alteration links proteome instability with genomic and phenotypic diversification

(2013) A. R. Bezerra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UGA is an additional glycine codon in uncultured SR1 bacteria from the human microbiota

(2013) J. H. Campbell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decameric SelAbullettRNASec Ring Structure Reveals Mechanism of Bacterial Selenocysteine Formation

(2013) Y. Itoh et al.   SCIENCE

Genomically Recoded Organisms Expand Biological Functions

(2013) M. J. Lajoie et al.   SCIENCE

Causes and Effects of N-Terminal Codon Bias in Bacterial Genes

(2013) D. B. Goodman et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Candida albicans CUG Mistranslation Is a Mechanism To Create Cell Surface Variation

(2013) I. Miranda et al.   mBio

A serine sensor for multicellularity in a bacterium

(2013) Arvind R Subramaniam et al.   eLife

Release Factor One Is Nonessential in Escherichia coli

(2012) David B. F. Johnson et al.   ACS Chemical Biology

Rewiring Translation for Elongation Factor Tu-Dependent Selenocysteine Incorporation

(2012) Caroline Aldag et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pyrrolysine Analogs as Substrates for Bacterial Pyrrolysyl-tRNA Synthetasein Vitroandin Vivo

(2012) Hidekazu KATAYAMA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Translational recoding in archaea

(2012) Beatrice Cobucci-Ponzano et al.   EXTREMOPHILES

Enhanced phosphoserine insertion duringEscherichia coliprotein synthesis via partial UAG codon reassignment and release factor 1 deletion

(2012) Ilka U. Heinemann et al.   FEBS LETTERS

N-Acetyl lysyl-tRNA synthetases evolved by a CcdB-based selection possessN-acetyl lysine specificity in vitro and in vivo

(2012) Takuya Umehara et al.   FEBS LETTERS

Genome Sequence of "Candidatus Methanomethylophilus alvus" Mx1201, a Methanogenic Archaeon from the Human Gut Belonging to a Seventh Order of Methanogens

(2012) G. Borrel et al.   JOURNAL OF BACTERIOLOGY

PylSn and the Homologous N-terminal Domain of Pyrrolysyl-tRNA Synthetase Bind the tRNA That Is Essential for the Genetic Encoding of Pyrrolysine

(2012) Ruisheng Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The anti-Shine–Dalgarno sequence drives translational pausing and codon choice in bacteria

(2012) Gene-Wei Li et al.   NATURE

RNA-guided genetic silencing systems in bacteria and archaea

(2012) Blake Wiedenheft et al.   NATURE

Selection of tRNA charging quality control mechanisms that increase mistranslation of the genetic code

(2012) Srujana S. Yadavalli et al.   NUCLEIC ACIDS RESEARCH

Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment

(2012) J. Ling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Carbon source-dependent expansion of the genetic code in bacteria

(2012) L. Prat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of Methylornithine Synthase (PylB): Insights into the Pyrrolysine Biosynthesis

(2011) Felix Quitterer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reprogramming the genetic code

(2011) Jason W Chin   EMBO JOURNAL

Genetic analysis of selenocysteine biosynthesis in the archaeon Methanococcus maripaludis

(2011) Michael J. Hohn et al.   MOLECULAR MICROBIOLOGY

The complete biosynthesis of the genetically encoded amino acid pyrrolysine from lysine

(2011) Marsha A. Gaston et al.   NATURE

An unusual tRNAThr derived from tRNAHis reassigns in yeast mitochondria the CUN codons to threonine

(2011) Dan Su et al.   NUCLEIC ACIDS RESEARCH

Naturally occurring aminoacyl-tRNA synthetases editing-domain mutations that cause mistranslation in Mycoplasma parasites

(2011) L. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Precise Manipulation of Chromosomes in Vivo Enables Genome-Wide Codon Replacement

(2011) Farren J. Isaacs et al.   SCIENCE

A Facile System for Genetic Incorporation of Two Different Noncanonical Amino Acids into One Protein inEscherichia coli

(2010) Wei Wan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Adding New Chemistries to the Genetic Code

(2010) Chang C. Liu et al.   Annual Review of Biochemistry

Residue-specific incorporation of non-canonical amino acids into proteins: recent developments and applications

(2010) Jeremiah A Johnson et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Selenoproteins—What unique properties can arise with selenocysteine in place of cysteine?

(2010) Elias S.J. Arnér   EXPERIMENTAL CELL RESEARCH

The Distinction Between Recoding and Codon Reassignment

(2010) J. F. Atkins et al.   GENETICS

Agmatine-conjugated cytidine in a tRNA anticodon is essential for AUA decoding in archaea

(2010) Yoshiho Ikeuchi et al.   Nature Chemical Biology

Synonymous but not the same: the causes and consequences of codon bias

(2010) Joshua B. Plotkin et al.   NATURE REVIEWS GENETICS

Codon reassignment in the Escherichia coli genetic code

(2010) T. Mukai et al.   NUCLEIC ACIDS RESEARCH

Agmatidine, a modified cytidine in the anticodon of archaeal tRNAIle, base pairs with adenosine but not with guanosine

(2010) D. Mandal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome

(2010) D. G. Gibson et al.   SCIENCE

Selenocysteine, Pyrrolysine, and the Unique Energy Metabolism of Methanogenic Archaea

(2010) Michael Rother et al.   ARCHAEA-AN INTERNATIONAL MICROBIOLOGICAL JOURNAL

Aminoacyl-tRNA Synthesis and Translational Quality Control

(2009) Jiqiang Ling et al.   Annual Review of Microbiology

The selenium to selenoprotein pathway in eukaryotes: More molecular partners than anticipated

(2009) Christine Allmang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Selenoproteins in Archaea and Gram-positive bacteria

(2009) Tilmann Stock et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The many levels of control on bacterial selenoprotein synthesis

(2009) Satoko Yoshizawa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Fidelity at the Molecular Level: Lessons from Protein Synthesis

(2009) Hani S. Zaher et al.   CELL

Translation termination in pyrrolysine-utilizing archaea

(2009) Elena Alkalaeva et al.   FEBS LETTERS

Distinct genetic code expansion strategies for selenocysteine and pyrrolysine are reflected in different aminoacyl-tRNA formation systems

(2009) Jing Yuan et al.   FEBS LETTERS

Eukaryotic Initiation Factor 4a3 Is a Selenium-Regulated RNA-Binding Protein that Selectively Inhibits Selenocysteine Incorporation

(2009) Michael E. Budiman et al.   MOLECULAR CELL

In vivorole of three fused corrinoid/methyl transfer proteins inMethanosarcina acetivorans

(2009) Ellen Oelgeschläger et al.   MOLECULAR MICROBIOLOGY

In vivorequirement of selenophosphate for selenoprotein synthesis in archaea

(2009) Tilmann Stock et al.   MOLECULAR MICROBIOLOGY

Pyrrolysyl-tRNA synthetase–tRNAPyl structure reveals the molecular basis of orthogonality

(2009) Kayo Nozawa et al.   NATURE

Innate immune and chemically triggered oxidative stress modifies translational fidelity

(2009) Nir Netzer et al.   NATURE

Programming cells by multiplex genome engineering and accelerated evolution

(2009) Harris H. Wang et al.   NATURE

The appearance of pyrrolysine in tRNAHisguanylyltransferase by neutral evolution

(2009) Ilka U. Heinemann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Code Supports Targeted Insertion of Two Amino Acids by One Codon

(2009) A. A. Turanov et al.   SCIENCE

The Human SepSecS-tRNASec Complex Reveals the Mechanism of Selenocysteine Formation

(2009) S. Palioura et al.   SCIENCE

How an obscure archaeal gene inspired the discovery of selenocysteine biosynthesis in humans

(2008) Dan Su et al.   IUBMB LIFE

Genetically encoding Nε-acetyllysine in recombinant proteins

(2008) Heinz Neumann et al.   Nature Chemical Biology

Characterization and evolutionary history of an archaeal kinase involved in selenocysteinyl-tRNA formation

(2008) R. Lynn Sherrer et al.   NUCLEIC ACIDS RESEARCH

Trends in Selenium Utilization in Marine Microbial World Revealed through the Analysis of the Global Ocean Sampling (GOS) Project

(2008) Yan Zhang et al.   PLoS Genetics