Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model

Targeting Autophagy to Counteract Obesity-Associated Oxidative Stress

(2021) Federico Pietrocola et al.   Antioxidants

Three-dimensional ultrastructure of giant mitochondria in human non-alcoholic fatty liver disease

(2021) Gerald J. Shami et al.   Scientific Reports

Mitochondria in epithelial ovarian carcinoma exhibit abnormal phenotypes and blunted associations with biobehavioral factors

(2021) Snehal Bindra et al.   Scientific Reports

The Hepatoprotective Effect of Taurisolo, a Nutraceutical Enriched in Resveratrol and Polyphenols, Involves Activation of Mitochondrial Metabolism in Mice Liver

(2020) Nadia Badolati et al.   Antioxidants

Mitochondrial dysfunction in metabolic syndrome

(2020) Pankaj Prasun   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The water extract of Sophorae tonkinensis Radix et Rhizoma alleviates non-alcoholic fatty liver disease and its mechanism

(2020) Qing Zhao et al.   PHYTOMEDICINE

The effect of saffron supplementation on some inflammatory and oxidative markers, leptin, adiponectin, and body composition in patients with nonalcoholic fatty liver disease: A double‐blind randomized clinical trial

(2020) Farnaz Kaviani Pour et al.   PHYTOTHERAPY RESEARCH

S100A10 Accelerates Aerobic Glycolysis and Malignant Growth by Activating mTOR-Signaling Pathway in Gastric Cancer

(2020) Yan Li et al.   Frontiers in Cell and Developmental Biology

The Crocus sativus Compounds trans-Crocin 4 and trans-Crocetin Modulate the Amyloidogenic Pathway and Tau Misprocessing in Alzheimer Disease Neuronal Cell Culture Models

(2019) Ioanna Chalatsa et al.   Frontiers in Neuroscience

Liang-Ge-San, a classic traditional Chinese medicine formula, attenuates acute inflammation in zebrafish and RAW 264.7 cells

(2019) Hongling Zhou et al.   JOURNAL OF ETHNOPHARMACOLOGY

Hepatoprotective and anti-inflammatory effects of total flavonoids of Qu Zhi Ke (peel of Citrus changshan-huyou) on non-alcoholic fatty liver disease in rats via modulation of NF-κB and MAPKs

(2019) Jianping Jiang et al.   PHYTOMEDICINE

Protective effect of Hedansanqi Tiaozhi Tang against non-alcoholic fatty liver disease in vitro and in vivo through activating Nrf2/HO-1 antioxidant signaling pathway

(2019) Mingyang Qiu et al.   PHYTOMEDICINE

Nonalcoholic fatty liver disease is an early predictor of metabolic diseases in a metabolically healthy population

(2019) Seokhun Yang et al.   PLoS One

The hepatoprotective effects of Salvia plebeia R. Br. extract in zebrafish (Danio rerio)

(2019) Guanghua Xiong et al.   FISH & SHELLFISH IMMUNOLOGY

Stability assessment of crocetin and crocetin derivatives in Gardenia yellow pigment and Gardenia fruit pomace in presence of different cooking methods

(2019) Na Li et al.   FOOD CHEMISTRY

Quality assessment of saffron ( Crocus sativus L.) extracts via UHPLC-DAD-MS analysis and detection of adulteration using gardenia fruit extract ( Gardenia jasminoides Ellis)

(2018) Benjamin Moras et al.   FOOD CHEMISTRY

Mitochondrial role in the neonatal predisposition to developing nonalcoholic fatty liver disease

(2018) Peter R. Baker et al.   JOURNAL OF CLINICAL INVESTIGATION

Ethanol and C2 ceramide activate fatty acid oxidation in human hepatoma cells

(2018) Jason M. Correnti et al.   Scientific Reports

The discovery of purine-based agents targeting triple-negative breast cancer and the αB-crystallin/VEGF protein–protein interaction

(2018) Nelly A. Fosu-Mensah et al.   MEDICINAL CHEMISTRY RESEARCH

Protective Effects of Aqueous Extracts of Flos lonicerae Japonicae against Hydroquinone-Induced Toxicity in Hepatic L02 Cells

(2018) Yanfang Gao et al.   Oxidative Medicine and Cellular Longevity

Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease

(2018) Ignazio Grattagliano et al.   BIOCHEMICAL PHARMACOLOGY

Toxicity comparison of different active fractions extracted from radix Sophorae tonkinensis in zebrafish

(2017) Hong-cui Liu et al.   Journal of Zhejiang University-SCIENCE B

The Natural Carotenoid Crocetin and the Synthetic Tellurium Compound AS101 Protect the Ovary against Cyclophosphamide by Modulating SIRT1 and Mitochondrial Markers

(2017) Giovanna Di Emidio et al.   Oxidative Medicine and Cellular Longevity

Antioxidant dietary approach in treatment of fatty liver: New insights and updates

(2017) Alessandra Ferramosca et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Water Extract ofDolichos lablabAttenuates Hepatic Lipid Accumulation in a Cellular Nonalcoholic Fatty Liver Disease Model

(2016) A-Rang Im et al.   JOURNAL OF MEDICINAL FOOD

ViableRNaseH1knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function

(2016) Walt F. Lima et al.   NUCLEIC ACIDS RESEARCH

Simultaneous quantification of crocetin esters and picrocrocin changes in Chinese saffron by high-performance liquid chromatography-diode array detector during 15 years of storage

(2015) Ping Wang et al.   Pharmacognosy Magazine

p53-mediated activation of the mitochondrial protease HtrA2/Omi prevents cell invasion

(2014) Shota Yamauchi et al.   JOURNAL OF CELL BIOLOGY

Hugan Qingzhi medication ameliorates hepatic steatosis by activating AMPK and PPARα pathways in L02 cells and HepG2 cells

(2014) JinJin Yin et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects of saffron extract and crocin on anthropometrical, nutritional and lipid profile parameters of rats fed a high fat diet

(2014) Maryam Mashmoul et al.   Journal of Functional Foods

Anticancer effects of crocetin in both human adenocarcinoma gastric cancer cells and rat model of gastric cancer

(2013) S. Zahra Bathaie et al.   Biochemistry and Cell Biology

Effect of intracellular lipid accumulation in a new model of non-alcoholic fatty liver disease

(2012) Norberto C Chavez-Tapia et al.   BMC GASTROENTEROLOGY