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Title
Pyroptosis and pyroptosis-inducing cancer drugs
Authors
Keywords
-
Journal
ACTA PHARMACOLOGICA SINICA
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-03-14
DOI
10.1038/s41401-022-00887-6
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Note: Only part of the references are listed.- NINJ1 mediates plasma membrane rupture during lytic cell death
- (2021) Nobuhiko Kayagaki et al. NATURE
- Caspase‐8: A key protein of cross‐talk signal way in “ PANoptosis ” in cancer
- (2021) Mingxia Jiang et al. INTERNATIONAL JOURNAL OF CANCER
- Pan-cancer analysis reveals the expression, genetic alteration and prognosis of pyroptosis key gene GSDMD
- (2021) Shizheng Qiu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis
- (2021) Rajendra Karki et al. Cell Reports
- The Versatile Gasdermin Family: Their Function and Roles in Diseases
- (2021) Ju Zou et al. Frontiers in Immunology
- Gasdermin E-derived caspase-3 inhibitors effectively protect mice from acute hepatic failure
- (2020) Wan-feng Xu et al. ACTA PHARMACOLOGICA SINICA
- Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
- (2020) Min Zheng et al. CELL
- The pyrin inflammasome in host–microbe interactions
- (2020) Nicole A Loeven et al. CURRENT OPINION IN MICROBIOLOGY
- Gasdermin E suppresses tumour growth by activating anti-tumour immunity
- (2020) Zhibin Zhang et al. NATURE
- A bioorthogonal system reveals antitumour immune function of pyroptosis
- (2020) Qinyang Wang et al. NATURE
- FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation
- (2020) Jun Jacob Hu et al. NATURE IMMUNOLOGY
- Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells
- (2020) Zhiwei Zhou et al. SCIENCE
- The NLRP1 and CARD8 inflammasomes
- (2020) Cornelius Y. Taabazuing et al. IMMUNOLOGICAL REVIEWS
- Human GBP1 Differentially Targets Salmonella and Toxoplasma to License Recognition of Microbial Ligands and Caspase-Mediated Death
- (2020) Daniel Fisch et al. Cell Reports
- Scutellarin inhibits caspase-11 activation and pyroptosis in macrophages via regulating PKA signaling
- (2020) Jie-zhou Ye et al. Acta Pharmaceutica Sinica B
- Miltirone induces cell death in hepatocellular carcinoma cell through GSDME-dependent pyroptosis
- (2020) Xiaowei Zhang et al. Acta Pharmaceutica Sinica B
- CARD8 inflammasome activation triggers pyroptosis in human T cells
- (2020) Andreas Linder et al. EMBO JOURNAL
- Pyroptosis is involved in the inhibitory effect of FL118 on growth and metastasis in colorectal cancer
- (2020) Zhenxue Tang et al. LIFE SCIENCES
- PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis
- (2020) Junwei Hou et al. NATURE CELL BIOLOGY
- Succination inactivates gasdermin D and blocks pyroptosis
- (2020) Fiachra Humphries et al. SCIENCE
- DPP8/9 inhibitors activate the CARD8 inflammasome in resting lymphocytes
- (2020) Darren C. Johnson et al. Cell Death & Disease
- NAIP-NLRC4-deficient mice are susceptible to shigellosis
- (2020) Patrick S Mitchell et al. eLife
- Molecular and Structural Basis of DNA Sensors in Antiviral Innate Immunity
- (2020) Ayesha Zahid et al. Frontiers in Immunology
- Cardamonin from a medicinal herb protects against LPS-induced septic shock by suppressing NLRP3 inflammasome
- (2019) Zhilei Wang et al. Acta Pharmaceutica Sinica B
- A PLK1 kinase inhibitor enhances the chemosensitivity of cisplatin by inducing pyroptosis in oesophageal squamous cell carcinoma
- (2019) Mengjiao Wu et al. EBioMedicine
- Chemotherapeutic paclitaxel and cisplatin differentially induce pyroptosis in A549 lung cancer cells via caspase-3/GSDME activation
- (2019) Cheng-cheng Zhang et al. APOPTOSIS
- Eukaryotic elongation factor-2 kinase regulates the cross-talk between autophagy and pyroptosis in doxorubicin-treated human melanoma cells in vitro
- (2019) Pian Yu et al. ACTA PHARMACOLOGICA SINICA
- Metformin induces human esophageal carcinoma cell pyroptosis by targeting the miR-497/PELP1 axis
- (2019) Lu Wang et al. CANCER LETTERS
- Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation
- (2019) Corey Rogers et al. Nature Communications
- Methylation analysis of Gasdermin E shows great promise as a biomarker for colorectal cancer
- (2019) Joe Ibrahim et al. Cancer Medicine
- α-NETA induces pyroptosis of epithelial ovarian cancer cells through the GSDMD/caspase-4 pathway
- (2019) Lianqiao Qiao et al. FASEB JOURNAL
- Cancer therapeutics using survivin BIRC5 as a target: what can we do after over two decades of study?
- (2019) Fengzhi Li et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis
- (2019) Sheng Li et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Gasdermin D activity in inflammation and host defense
- (2019) Judy Lieberman et al. Science Immunology
- Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity–independent pyroptosis, apoptosis, necroptosis, and inflammatory disease
- (2019) R.K. Subbarao Malireddi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Pharmacological actions of miltirone in the modulation of platelet function
- (2018) Wei Song et al. ACTA PHARMACOLOGICA SINICA
- Mechanism of membrane pore formation by human gasdermin‐D
- (2018) Estefania Mulvihill et al. EMBO JOURNAL
- A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis
- (2018) Ronald A. Panganiban et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation
- (2018) R.K. Subbarao Malireddi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia
- (2018) Darren C. Johnson et al. NATURE MEDICINE
- Cryo-EM structure of the gasdermin A3 membrane pore
- (2018) Jianbin Ruan et al. NATURE
- Targeting the NLRP3 inflammasome in inflammatory diseases
- (2018) Matthew S. J. Mangan et al. NATURE REVIEWS DRUG DISCOVERY
- Anthocyanin is Involved in the Activation of Pyroptosis in Oral Squamous Cell Carcinoma
- (2018) Er Yue et al. PHYTOMEDICINE
- A thiopyran derivative with low murine toxicity with therapeutic potential on lung cancer acting through a NF-κB mediated apoptosis-to-pyroptosis switch
- (2018) Liping Chen et al. APOPTOSIS
- Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis
- (2018) Bo Zhou et al. CELL RESEARCH
- Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding
- (2018) Franklin L. Zhong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The AIM2 inflammasome: Sensor of pathogens and cellular perturbations
- (2017) Jérôme Lugrin et al. IMMUNOLOGICAL REVIEWS
- Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
- (2017) Yupeng Wang et al. NATURE
- NLRP3 Inflammasome as a Molecular Marker in Diabetic Cardiomyopathy
- (2017) Beibei Luo et al. Frontiers in Physiology
- Effects of anthocyanins on the prevention and treatment of cancer
- (2016) Bo-Wen Lin et al. BRITISH JOURNAL OF PHARMACOLOGY
- NLRP3 recruitment by NLRC4 duringSalmonellainfection
- (2016) Yan Qu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Pore-forming activity and structural autoinhibition of the gasdermin family
- (2016) Jingjin Ding et al. NATURE
- Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease
- (2016) Alexander R. Bogdan et al. TRENDS IN BIOCHEMICAL SCIENCES
- Gasdermin C Is Upregulated by Inactivation of Transforming Growth Factor β Receptor Type II in the Presence of Mutated Apc, Promoting Colorectal Cancer Proliferation
- (2016) Masashi Miguchi et al. PLoS One
- The NAIP/NLRC4 inflammasomes
- (2015) Russell E Vance CURRENT OPINION IN IMMUNOLOGY
- AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunity
- (2015) Si Ming Man et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The NLRP1 inflammasomes
- (2015) Joseph Chavarría-Smith et al. IMMUNOLOGICAL REVIEWS
- Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
- (2015) Nobuhiko Kayagaki et al. NATURE
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- Molecular Basis for Specific Recognition of Bacterial Ligands by NAIP/NLRC4 Inflammasomes
- (2014) Jeannette L. Tenthorey et al. MOLECULAR CELL
- An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome
- (2014) Scott W Canna et al. NATURE GENETICS
- A Novel CMKLR1 Small Molecule Antagonist Suppresses CNS Autoimmune Inflammatory Disease
- (2014) Kareem L. Graham et al. PLoS One
- Targeting elongation factor-2 kinase (eEF-2K) induces apoptosis in human pancreatic cancer cells
- (2013) Ahmed A. Ashour et al. APOPTOSIS
- Arsenic Trioxide and Other Arsenical Compounds Inhibit the NLRP1, NLRP3, and NAIP5/NLRC4 Inflammasomes
- (2013) N. K. Maier et al. JOURNAL OF IMMUNOLOGY
- Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection
- (2013) Gilad Doitsh et al. NATURE
- Effects of vitamin B6 metabolism on oncogenesis, tumor progression and therapeutic responses
- (2013) L Galluzzi et al. ONCOGENE
- Inflammasome Components Coordinate Autophagy and Pyroptosis as Macrophage Responses to Infection
- (2013) B. G. Byrne et al. mBio
- Functional Conservation of Gsdma Cluster Genes Specifically Duplicated in the Mouse Genome
- (2013) Shigekazu Tanaka et al. G3-Genes Genomes Genetics
- Cytoskeleton responses in wound repair
- (2012) Maria Teresa Abreu-Blanco et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- NLRC4 Inflammasome-Mediated Production of IL-1 Modulates Mucosal Immunity in the Lung against Gram-Negative Bacterial Infection
- (2012) S. Cai et al. JOURNAL OF IMMUNOLOGY
- Non-canonical inflammasome activation targets caspase-11
- (2011) Nobuhiko Kayagaki et al. NATURE
- Polymorphisms in GSDMA and GSDMB are associated with asthma susceptibility, atopy and BHR
- (2011) Jinho Yu et al. PEDIATRIC PULMONOLOGY
- The Inflammasomes
- (2010) Kate Schroder et al. CELL
- Docosahexaenoic acid intake decreases proliferation, increases apoptosis and decreases the invasive potential of the human breast carcinoma cell line MDA-MB-231
- (2010) Blanckaert INTERNATIONAL JOURNAL OF ONCOLOGY
- Delineating Immune-Mediated Mechanisms Underlying Hair Follicle Destruction in the Mouse Mutant Defolliculated
- (2010) Fiona Ruge et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Docosahexaenoic Acid Induces Apoptosis in MCF-7 Cells In Vitro and In Vivo via Reactive Oxygen Species Formation and Caspase 8 Activation
- (2010) Ki Sung Kang et al. PLoS One
- Anthocyanins: Natural Colorants with Health-Promoting Properties
- (2010) Jian He et al. Annual Review of Food Science and Technology
- An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans
- (2009) Amy G. Hise et al. Cell Host & Microbe
- The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1
- (2009) Paul G. Thomas et al. IMMUNITY
- Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
- (2009) Mohamed Lamkanfi et al. JOURNAL OF CELL BIOLOGY
- Involvement of the NLRP3 Inflammasome in Innate and Humoral Adaptive Immune Responses to Fungal -Glucan
- (2009) H. Kumar et al. JOURNAL OF IMMUNOLOGY
- Distinctive expression and function of fourGSDMfamily genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium
- (2008) Norihisa Saeki et al. GENES CHROMOSOMES & CANCER
- The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
- (2008) Daniel A. Muruve et al. NATURE
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