DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia
Authors
Keywords
-
Journal
NATURE MEDICINE
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2018-06-29
DOI
10.1038/s41591-018-0082-y
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Unravelling the immunological roles of dipeptidyl peptidase 4 (DPP4) activity and/or structure homologue (DASH) proteins
- (2016) L. Wagner et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias
- (2016) K Wang et al. LEUKEMIA
- Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
- (2016) John G Doench et al. NATURE BIOTECHNOLOGY
- DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis
- (2016) Marian C Okondo et al. Nature Chemical Biology
- Acute myeloid leukaemia
- (2016) Asim Khwaja et al. Nature Reviews Disease Primers
- BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis
- (2015) Frederik Otzen Bagger et al. NUCLEIC ACIDS RESEARCH
- A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity
- (2014) Daniel A Bachovchin et al. Nature Chemical Biology
- Improved vectors and genome-wide libraries for CRISPR screening
- (2014) Neville E Sanjana et al. NATURE METHODS
- Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function
- (2014) Baptiste Guey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation
- (2014) Nina Van Opdenbosch et al. Nature Communications
- Inhibition of intracellular dipeptidyl peptidases 8 and 9 enhances parthenolide’s anti-leukemic activity
- (2013) P A Spagnuolo et al. LEUKEMIA
- Advances in Understanding the Expression and Function of Dipeptidyl Peptidase 8 and 9
- (2013) H. Zhang et al. MOLECULAR CANCER RESEARCH
- Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
- (2013) NEW ENGLAND JOURNAL OF MEDICINE
- Val-BoroPro Accelerates T Cell Priming via Modulation of Dendritic Cell Trafficking Resulting in Complete Regression of Established Murine Tumors
- (2013) Meghaan P. Walsh et al. PLoS One
- The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
- (2012) Jordi Barretina et al. NATURE
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- Proteolytic Processing of Nlrp1b Is Required for Inflammasome Activity
- (2012) Bradley C. Frew et al. PLoS Pathogens
- Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor
- (2011) Scott R. Daigle et al. CANCER CELL
- Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis
- (2011) Noa Novershtern et al. CELL
- CARD8 and NLRP1 Undergo Autoproteolytic Processing through a ZU5-Like Domain
- (2011) Andrea D'Osualdo et al. PLoS One
- Differential Requirement for Caspase-1 Autoproteolysis in Pathogen-Induced Cell Death and Cytokine Processing
- (2010) Petr Broz et al. Cell Host & Microbe
- Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor
- (2009) Jia-Jing Wu et al. BIOCHEMICAL PHARMACOLOGY
- Phase II assessment of talabostat and cisplatin in second-line stage IV melanoma
- (2009) Robert M Eager et al. BMC CANCER
- Phase II Trial of Talabostat and Docetaxel in Advanced Non-small Cell Lung Cancer
- (2009) R.M. Eager et al. CLINICAL ONCOLOGY
- Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: Isoindoline containing inhibitors
- (2008) Sebastiaan Van Goethem et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The NLR Gene Family: A Standard Nomenclature
- (2008) Jenny P.-Y. Ting et al. IMMUNITY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started