Targeting elongation factor-2 kinase (eEF-2K) induces apoptosis in human pancreatic cancer cells

Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells

(2014) Ugur Akar et al.   Autophagy

Rottlerin induces autophagy which leads to apoptotic cell death through inhibition of PI3K/Akt/mTOR pathway in human pancreatic cancer stem cells

(2012) Brahma N. Singh et al.   BIOCHEMICAL PHARMACOLOGY

Investigating the Kinetic Mechanism of Inhibition of Elongation Factor 2 Kinase by NH125: Evidence of a Common in Vitro Artifact

(2012) Ashwini K. Devkota et al.   BIOCHEMISTRY

DJ-1 promotes invasion and metastasis of pancreatic cancer cells by activating SRC/ERK/uPA

(2012) Xiangyi He et al.   CARCINOGENESIS

Targeted Silencing of Elongation Factor 2 Kinase Suppresses Growth and Sensitizes Tumors to Doxorubicin in an Orthotopic Model of Breast Cancer

(2012) Ibrahim Tekedereli et al.   PLoS One

Rottlerin and Cancer: Novel Evidence and Mechanisms

(2012) E. Maioli et al.   TheScientificWorldJOURNAL

eEF-2 Kinase Dictates Cross-Talk between Autophagy and Apoptosis Induced by Akt Inhibition, Thereby Modulating Cytotoxicity of Novel Akt Inhibitor MK-2206

(2011) Y. Cheng et al.   CANCER RESEARCH

Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics

(2011) Jean-Claude Martinou et al.   DEVELOPMENTAL CELL

Cytoprotective Effect of the Elongation Factor-2 Kinase-Mediated Autophagy in Breast Cancer Cells Subjected to Growth Factor Inhibition

(2010) Yan Cheng et al.   PLoS One

Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family

(2009) Izumi Ohno et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Silencing of Elongation Factor-2 Kinase Potentiates the Effect of 2-Deoxy-D-Glucose against Human Glioma Cells through Blunting of Autophagy

(2009) H. Wu et al.   CANCER RESEARCH