Tumor Associated Macrophages: Origin, Recruitment, Phenotypic Diversity, and Targeting
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Title
Tumor Associated Macrophages: Origin, Recruitment, Phenotypic Diversity, and Targeting
Authors
Keywords
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Journal
Frontiers in Oncology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-12-20
DOI
10.3389/fonc.2021.788365
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Note: Only part of the references are listed.- Targeting CX3CR1 Suppresses the Fanconi Anemia DNA Repair Pathway and Synergizes with Platinum
- (2021) Jemina Lehto et al. Cancers
- A Phase I Study of APX005M and Cabiralizumab with or without Nivolumab in Patients with Melanoma, Kidney Cancer, or Non–Small Cell Lung Cancer Resistant to Anti-PD-1/PD-L1
- (2021) Sarah A. Weiss et al. CLINICAL CANCER RESEARCH
- Tumor Extracellular Vesicles Regulate Macrophage-Driven Metastasis through CCL5
- (2021) Daniel C. Rabe et al. Cancers
- CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling in esophageal carcinogenesis
- (2020) Hui Yang et al. Molecular Cancer
- RACK1 promotes cancer progression by increasing the M2/M1 macrophage ratio via the NF‐κB pathway in oral squamous cell carcinoma
- (2020) Hongxia Dan et al. Molecular Oncology
- Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses
- (2020) Jesse M. Jaynes et al. Science Translational Medicine
- Use of Programmed Death Receptor-1 and/or Programmed Death Ligand 1 Inhibitors for the Treatment of Brain Metastasis of Lung Cancer
- (2020) Shiqiang Wang et al. OncoTargets and Therapy
- Advances in Anti-Tumor Treatments Targeting the CD47/SIRPα Axis
- (2020) Wenting Zhang et al. Frontiers in Immunology
- Role of Interleukin-34 in Cancer
- (2020) Eleonora Franzè et al. Cancers
- Acquired Resistance to Immune Checkpoint Inhibitors
- (2020) Adam J. Schoenfeld et al. CANCER CELL
- Results of a first-in-human phase I study of SRF231, a fully human, high-affinity anti-CD47 antibody.
- (2020) Amita Patnaik et al. JOURNAL OF CLINICAL ONCOLOGY
- CCL3–CCR5 axis contributes to progression of esophageal squamous cell carcinoma by promoting cell migration and invasion via Akt and ERK pathways
- (2020) Takayuki Kodama et al. LABORATORY INVESTIGATION
- Targeting pro-tumoral macrophages in early primary and metastatic breast tumors with CD206-binding mUNO peptide
- (2020) Anni Lepland et al. MOLECULAR PHARMACEUTICS
- Role of M1-polarized tumor-associated macrophages in the prognosis of advanced ovarian cancer patients
- (2020) Antonio Macciò et al. Scientific Reports
- Determinants of Resident Tissue Macrophage Identity and Function
- (2020) Camille Blériot et al. IMMUNITY
- Nanoparticle delivery of immunostimulatory oligonucleotides enhances response to checkpoint inhibitor therapeutics
- (2020) Colin G. Buss et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The CCL5/CCR5 Axis in Cancer Progression
- (2020) Donatella Aldinucci et al. Cancers
- Peptide-guided resiquimod-loaded lignin nanoparticles convert tumor-associated macrophages from M2 to M1 phenotype for enhanced chemotherapy
- (2020) Patrícia Figueiredo et al. Acta Biomaterialia
- CC Chemokines in a Tumor: A Review of Pro-Cancer and Anti-Cancer Properties of Receptors CCR5, CCR6, CCR7, CCR8, CCR9, and CCR10 Ligands
- (2020) Jan Korbecki et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- CD47/SIRPα blocking peptide identification and synergistic effect with irradiation for cancer immunotherapy
- (2020) Hongfei Wang et al. Journal for ImmunoTherapy of Cancer
- Tumor-derived adenosine promotes macrophage proliferation in human hepatocellular carcinoma
- (2020) Junfeng Wang et al. JOURNAL OF HEPATOLOGY
- Phase I dose-escalation study of chiauranib, a novel angiogenic, mitotic, and chronic inflammation inhibitor, in patients with advanced solid tumors
- (2019) Yongkun Sun et al. Journal of Hematology & Oncology
- Exosomes from differentially activated macrophages influence dormancy or resurgence of breast cancer cells within bone marrow stroma
- (2019) Nykia D. Walker et al. Cell Death & Disease
- Surface Modification of Polymeric Nanoparticles with M2pep Peptide for Drug Delivery to Tumor-Associated Macrophages
- (2019) Liang Pang et al. PHARMACEUTICAL RESEARCH
- Phage-Display-Derived Peptide Binds to Human CD206 and Modeling Reveals a New Binding Site on the Receptor
- (2019) Eliana K. Asciutto et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Monocyte heterogeneity and functions in cancer
- (2019) Claire E. Olingy et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Macrophages derived exosomes deliver miR-223 to epithelial ovarian cancer cells to elicit a chemoresistant phenotype
- (2019) Xiaolan Zhu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- CXCL12/CXCR4 promotes inflammation-driven colorectal cancer progression through activation of RhoA signaling by sponging miR-133a-3p
- (2019) Xinfeng Yu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- First-in-Human, First-in-Class Phase I Trial of the Anti-CD47 Antibody Hu5F9-G4 in Patients With Advanced Cancers
- (2019) Branimir I. Sikic et al. JOURNAL OF CLINICAL ONCOLOGY
- Depletion of tumor-associated macrophages enhances the anti-tumor effect of docetaxel in a murine epithelial ovarian cancer
- (2019) Xiaofen Lu et al. IMMUNOBIOLOGY
- Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer
- (2019) Christopher J. Halbrook et al. Cell Metabolism
- Tumor-associated macrophages modulate resistance to oxaliplatin via inducing autophagy in hepatocellular carcinoma
- (2019) Xiu-Tao Fu et al. Cancer Cell International
- Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets
- (2019) Luca Cassetta et al. CANCER CELL
- Zoledronic Acid-containing Nanoparticles With Minimum Premature Release Show Enhanced Activity Against Extraskeletal Tumor
- (2019) Xu Li et al. ACS Applied Materials & Interfaces
- Cooperatively Responsive Peptide Nanotherapeutic that Regulates Angiopoietin Receptor Tie2 Activity in Tumor Microenvironment To Prevent Breast Tumor Relapse after Chemotherapy
- (2019) Lijing Zhang et al. ACS Nano
- CXCL12/CXCR4 pathway orchestrates CSC-like properties by CAF recruited tumor associated macrophage in OSCC
- (2019) Xing Li et al. EXPERIMENTAL CELL RESEARCH
- The transcriptional factors HIF-1 and HIF-2 and their novel inhibitors in cancer therapy
- (2019) Najah Albadari et al. Expert Opinion on Drug Discovery
- Transforming Growth Factor-β Signaling in Immunity and Cancer
- (2019) Eduard Batlle et al. IMMUNITY
- Tumor-specific macrophage targeting through recognition of retinoid X receptor beta
- (2019) Tang Tang et al. JOURNAL OF CONTROLLED RELEASE
- Targeted Delivery of Zoledronate to Tumor-Associated Macrophages for Cancer Immunotherapy
- (2019) Xinlong Zang et al. MOLECULAR PHARMACEUTICS
- CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors
- (2019) Andrea Walens et al. eLife
- Interaction of tumor-associated macrophages and cancer chemotherapy
- (2019) Irina Larionova et al. OncoImmunology
- Macrophage Polarization in the Development and Progression of Ovarian Cancers: An Overview
- (2019) Huiyan Cheng et al. Frontiers in Oncology
- Management of bone health in solid tumours: From bisphosphonates to a monoclonal antibody
- (2019) Roger von Moos et al. CANCER TREATMENT REVIEWS
- Re-education of macrophages as a therapeutic strategy in cancer
- (2019) Joanna Kowal et al. Immunotherapy
- Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of metastatic pancreatic ductal adenocarcinoma
- (2019) Marcus Noel et al. INVESTIGATIONAL NEW DRUGS
- Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications
- (2019) Yuxin Lin et al. Journal of Hematology & Oncology
- Hypoxia-induced ZEB1 promotes cervical cancer progression via CCL8-dependent tumour-associated macrophage recruitment
- (2019) Xiao-Jing Chen et al. Cell Death & Disease
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- (2019) Wei-Chi Hsu et al. DISEASE MARKERS
- Macrophages and hepatocellular carcinoma
- (2019) Zhiqiang Tian et al. Cell and Bioscience
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- (2019) Yuan Tian et al. Aging-US
- Pexidartinib: First Approval
- (2019) Yvette N. Lamb DRUGS
- CD206+ tumor-associated macrophages promote proliferation and invasion in oral squamous cell carcinoma via EGF production
- (2019) A. S. M. Rafiul Haque et al. Scientific Reports
- Tumor-Infiltrating Immune Cells Act as a Marker for Prognosis in Colorectal Cancer
- (2019) Lele Ye et al. Frontiers in Immunology
- Harnessing tumor-associated macrophages as aids for cancer immunotherapy
- (2019) Xiaolei Li et al. Molecular Cancer
- Reversibly Switchable, pH-Dependent Peptide Ligand Binding via 3,5-Diiodotyrosine Substitutions
- (2018) Chayanon Ngambenjawong et al. ACS Chemical Biology
- Altered monocyte differentiation and macrophage polarization patterns in patients with breast cancer
- (2018) Chih-Hsing Hung et al. BMC CANCER
- Distribution of M1 and M2 macrophages in tumor islets and stroma in relation to prognosis of non-small cell lung cancer
- (2018) Jurgita Jackute et al. BMC IMMUNOLOGY
- Trastuzumab upregulates PD-L1 as a potential mechanism of trastuzumab resistance through engagement of immune effector cells and stimulation of IFNγ secretion
- (2018) Bharat K.R. Chaganty et al. CANCER LETTERS
- Inhibition of Rspo-Lgr4 facilitates checkpoint blockade therapy by switching macrophage polarization
- (2018) Binghe Tan et al. CANCER RESEARCH
- Targeting the microenvironment in solid tumors
- (2018) Carmen Belli et al. CANCER TREATMENT REVIEWS
- CCL18 – Beyond chemotaxis
- (2018) Cecile Chenivesse et al. CYTOKINE
- CXCR4/CXCL12 Signaling and Protumor Macrophages in Primary Tumors and Sentinel Lymph Nodes Are Involved in Luminal B Breast Cancer Progression
- (2018) Carlotta Raschioni et al. DISEASE MARKERS
- Expression of scavenger receptor MARCO defines a targetable tumor-associated macrophage subset in non-small cell lung cancer
- (2018) Linnéa La Fleur et al. INTERNATIONAL JOURNAL OF CANCER
- Inhibition of the CCL5/CCR5 Axis against the Progression of Gastric Cancer
- (2018) Donatella Aldinucci et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Tumor-associated macrophages promote progression and the Warburg effect via CCL18/NF-kB/VCAM-1 pathway in pancreatic ductal adenocarcinoma
- (2018) Huilin Ye et al. Cell Death & Disease
- Angiogenic factor-driven inflammation promotes extravasation of human proangiogenic monocytes to tumours
- (2018) Adama Sidibe et al. Nature Communications
- TIE2-expressing monocytes and M2-polarized macrophages impact survival and correlate with angiogenesis in adenocarcinoma of the pancreas
- (2018) Georgi Atanasov et al. Oncotarget
- Effect of CCL5 expression in the recruitment of immune cells in triple negative breast cancer
- (2018) Jhajaira M. Araujo et al. Scientific Reports
- A Unidirectional Transition from Migratory to Perivascular Macrophage Is Required for Tumor Cell Intravasation
- (2018) Esther N. Arwert et al. Cell Reports
- Stromal Infiltration of Tumor-Associated Macrophages Conferring Poor Prognosis of Patients with Basal-Like Breast Carcinoma
- (2018) Mu Yang et al. Journal of Cancer
- TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy
- (2018) Christopher B. Rodell et al. Nature Biomedical Engineering
- Tumor-associated macrophages derived CCL18 promotes metastasis in squamous cell carcinoma of the head and neck
- (2018) Li She et al. Cancer Cell International
- Paclitaxel reduces tumor growth by reprogramming tumor-associated macrophages to an M1- profile in a TLR4-dependent manner
- (2018) Carlos W Wanderley et al. CANCER RESEARCH
- Inhibition of TAMs improves the response to docetaxel in castration-resistant prostate cancer
- (2018) Wei Guan et al. ENDOCRINE-RELATED CANCER
- Macrophages of distinct origins contribute to tumor development in the lung
- (2018) Pierre-Louis Loyher et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Recruitment of CCR2+ tumor associated macrophage to sites of liver metastasis confers a poor prognosis in human colorectal cancer
- (2018) Julie G Grossman et al. OncoImmunology
- The clinical role of the TME in solid cancer
- (2018) Nicolas A. Giraldo et al. BRITISH JOURNAL OF CANCER
- Pharmacokinetics, Pharmacodynamics, and Safety of E6011, a Novel Humanized Antifractalkine (CX3CL1) Monoclonal Antibody: A Randomized, Double-Blind, Placebo-Controlled Single-Ascending-Dose Study
- (2018) Hiroko Tabuchi et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Macrophage-derived CCL18 promotes osteosarcoma proliferation and migration by upregulating the expression of UCA1
- (2018) Yang Su et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- The relationship between chemokines CCL2, CCL3, and CCL4 with the tumor microenvironment and tumor-associated macrophage markers in colorectal cancer
- (2018) Marjorie De la Fuente López et al. TUMOR BIOLOGY
- CCL18 secreted from M2 macrophages promotes migration and invasion via the PI3K/Akt pathway in gallbladder cancer
- (2018) Zhenyu Zhou et al. CELLULAR ONCOLOGY
- The Role of the Extracellular Matrix and Its Molecular and Cellular Regulators in Cancer Cell Plasticity
- (2018) Valentina Poltavets et al. Frontiers in Oncology
- Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression
- (2017) Yu Zhu et al. IMMUNITY
- PD-L1 induced by IFN-γ from tumor-associated macrophages via the JAK/STAT3 and PI3K/AKT signaling pathways promoted progression of lung cancer
- (2017) Xiaohui Zhang et al. International Journal of Clinical Oncology
- M2-like macrophages induce colon cancer cell invasion via matrix metalloproteinases
- (2017) Katyayni Vinnakota et al. JOURNAL OF CELLULAR PHYSIOLOGY
- IL4 Receptor–Targeted Proapoptotic Peptide Blocks Tumor Growth and Metastasis by Enhancing Antitumor Immunity
- (2017) Sri Murugan Poongkavithai Vadevoo et al. MOLECULAR CANCER THERAPEUTICS
- Colony-Stimulating Factor 1 Receptor Blockade Inhibits Tumor Growth by Altering the Polarization of Tumor-Associated Macrophages in Hepatocellular Carcinoma
- (2017) Jian-Yang Ao et al. MOLECULAR CANCER THERAPEUTICS
- Tumour-associated macrophages as treatment targets in oncology
- (2017) Alberto Mantovani et al. Nature Reviews Clinical Oncology
- Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas
- (2017) D Yan et al. ONCOGENE
- IL-6 Mediates Macrophage Infiltration after Irradiation via Up-regulation of CCL2/CCL5 in Non-small Cell Lung Cancer
- (2017) Xin Wang et al. RADIATION RESEARCH
- CSF-1R Inhibitor Development: Current Clinical Status
- (2017) Florent Peyraud et al. Current Oncology Reports
- Melittin suppresses tumor progression by regulating tumor-associated macrophages in a Lewis lung carcinoma mouse model
- (2017) Chanju Lee et al. Oncotarget
- Tumor-Associated Lymphatic Vessels Upregulate PDL1 to Inhibit T-Cell Activation
- (2017) Lothar C. Dieterich et al. Frontiers in Immunology
- Host antitumor resistance improved by the macrophage polarization in a chimera model of patients with HCC
- (2017) Akira Asai et al. OncoImmunology
- TIE-2 expressing monocytes in human cancers
- (2017) Riccardo Turrini et al. OncoImmunology
- The Prognostic and Clinicopathological Significance of Tumor-Associated Macrophages in Patients with Gastric Cancer: A Meta-Analysis
- (2017) Songcheng Yin et al. PLoS One
- Precision Targeting of Tumor Macrophages with a CD206 Binding Peptide
- (2017) Pablo Scodeller et al. Scientific Reports
- Engineering an Affinity-Enhanced Peptide through Optimization of Cyclization Chemistry
- (2016) Chayanon Ngambenjawong et al. BIOCONJUGATE CHEMISTRY
- Carboxyl- and amino-functionalized polystyrene nanoparticles differentially affect the polarization profile of M1 and M2 macrophage subsets
- (2016) Ann-Kathrin Fuchs et al. BIOMATERIALS
- Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients
- (2016) Niels Halama et al. CANCER CELL
- Role of chemokine pathways in hepatobiliary cancer
- (2016) Josef Ehling et al. CANCER LETTERS
- Inhibiting macrophage PI3Kγ to enhance immunotherapy
- (2016) Wei Zheng et al. CELL RESEARCH
- Tumor-Derived CCL2 Mediates Resistance to Radiotherapy in Pancreatic Ductal Adenocarcinoma
- (2016) Anusha Kalbasi et al. CLINICAL CANCER RESEARCH
- Lurbinectedin induces depletion of tumor-associated macrophages, an essential component of itsin vivosynergism with gemcitabine, in pancreatic adenocarcinoma mouse models
- (2016) María Virtudes Céspedes et al. Disease Models & Mechanisms
- Pharmacological macrophage inhibition decreases metastasis formation in a genetic model of pancreatic cancer
- (2016) Heidi Griesmann et al. GUT
- Phase I clinical and pharmacokinetic study of PM01183 (a tetrahydroisoquinoline, Lurbinectedin) in combination with gemcitabine in patients with advanced solid tumors
- (2016) Luis Paz-Ares et al. INVESTIGATIONAL NEW DRUGS
- The impact of hypoxia on tumor-associated macrophages
- (2016) Anne-Theres Henze et al. JOURNAL OF CLINICAL INVESTIGATION
- Efficacy and Safety of Trabectedin or Dacarbazine for Metastatic Liposarcoma or Leiomyosarcoma After Failure of Conventional Chemotherapy: Results of a Phase III Randomized Multicenter Clinical Trial
- (2016) George D. Demetri et al. JOURNAL OF CLINICAL ONCOLOGY
- A novel liposomal Clodronate depletes tumor-associated macrophages in primary and metastatic melanoma: Anti-angiogenic and anti-tumor effects
- (2016) F. Piaggio et al. JOURNAL OF CONTROLLED RELEASE
- Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial
- (2016) Timothy M Nywening et al. LANCET ONCOLOGY
- Novel Small-Molecule CX3CR1 Antagonist Impairs Metastatic Seeding and Colonization of Breast Cancer Cells
- (2016) F. Shen et al. MOLECULAR CANCER RESEARCH
- CC chemokine ligand 18(CCL18) promotes migration and invasion of lung cancer cells by binding to Nir1 through Nir1-ELMO1/DOC180 signaling pathway
- (2016) Lihong Shi et al. MOLECULAR CARCINOGENESIS
- Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues
- (2016) Saeid Zanganeh et al. Nature Nanotechnology
- Dysregulation of macrophage polarization is associated with the metastatic process in osteosarcoma
- (2016) Clotilde Dumars et al. Oncotarget
- Prognostic impact of tumor-associated macrophage infiltration in non-small cell lung cancer: A systemic review and meta-analysis
- (2016) Jiandong Mei et al. Oncotarget
- Tumor-infiltrating immune cell subpopulations influence the oncologic outcome after intravesical Bacillus Calmette-Guérin therapy in bladder cancer
- (2016) Renate Pichler et al. Oncotarget
- Serum Stability and Affinity Optimization of an M2 Macrophage-Targeting Peptide (M2pep)
- (2016) Chayanon Ngambenjawong et al. Theranostics
- CCL2 as a potential therapeutic target for clear cell renal cell carcinoma
- (2016) Ryuichiro Arakaki et al. Cancer Medicine
- Hepatocellular carcinoma is accelerated by NASH involving M2 macrophage polarization mediated by hif-1αinduced IL-10
- (2016) Aditya Ambade et al. OncoImmunology
- Macrophage and Cancer Cell Cross-talk via CCR2 and CX3CR1 Is a Fundamental Mechanism Driving Lung Cancer
- (2015) Anja Schmall et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- SIRP/CD47 signaling in neurological disorders
- (2015) Haiyue Zhang et al. BRAIN RESEARCH
- M-CSF and GM-CSF Receptor Signaling Differentially Regulate Monocyte Maturation and Macrophage Polarization in the Tumor Microenvironment
- (2015) E. Van Overmeire et al. CANCER RESEARCH
- Metastasis Suppressors Regulate the Tumor Microenvironment by Blocking Recruitment of Prometastatic Tumor-Associated Macrophages
- (2015) C. Frankenberger et al. CANCER RESEARCH
- Clinical and Biological Effects of an Agonist Anti-CD40 Antibody: A Cancer Research UK Phase I Study
- (2015) P. Johnson et al. CLINICAL CANCER RESEARCH
- Targeting of tumour-infiltrating macrophages via CCL2/CCR2 signalling as a therapeutic strategy against hepatocellular carcinoma
- (2015) Xiaoguang Li et al. GUT
- HIF-1 at the crossroads of hypoxia, inflammation, and cancer
- (2015) Kuppusamy Balamurugan INTERNATIONAL JOURNAL OF CANCER
- CCL2-induced chemokine cascade promotes breast cancer metastasis by enhancing retention of metastasis-associated macrophages
- (2015) Takanori Kitamura et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Sorafenib inhibits macrophage-induced growth of hepatoma cells by interference with insulin-like growth factor-1 secretion
- (2015) Martin Franz Sprinzl et al. JOURNAL OF HEPATOLOGY
- High infiltration of tumor-associated macrophages is associated with a poor response to chemotherapy and poor prognosis of patients undergoing neoadjuvant chemotherapy for esophageal cancer
- (2015) Keijiro Sugimura et al. JOURNAL OF SURGICAL ONCOLOGY
- The chemokine receptor CCR6 facilitates the onset of mammary neoplasia in the MMTV-PyMT mouse model via recruitment of tumor-promoting macrophages
- (2015) Sarah T. Boyle et al. Molecular Cancer
- Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
- (2015) Bruno Costa-Silva et al. NATURE CELL BIOLOGY
- Colony stimulating factor 1 receptor inhibition delays recurrence of glioblastoma after radiation by altering myeloid cell recruitment and polarization
- (2015) Jason H. Stafford et al. NEURO-ONCOLOGY
- Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway
- (2015) Kim C. Ohaegbulam et al. TRENDS IN MOLECULAR MEDICINE
- CCL18/PITPNM3 enhances migration, invasion, and EMT through the NF-κB signaling pathway in hepatocellular carcinoma
- (2015) Zeyu Lin et al. TUMOR BIOLOGY
- CCL18 promotes the invasion and migration of gastric cancer cells via ERK1/2/NF-κB signaling pathway
- (2015) Xu Hou et al. TUMOR BIOLOGY
- Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis
- (2015) Xi Feng et al. Oncotarget
- RKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by controlling macrophage infiltration
- (2015) Ila Datar et al. Oncotarget
- Contact-dependent carcinoma aggregate dispersion by M2a macrophages via ICAM-1 and β2 integrin interactions
- (2015) Jing Bai et al. Oncotarget
- Opposite Effects of M1 and M2 Macrophage Subtypes on Lung Cancer Progression
- (2015) Ang Yuan et al. Scientific Reports
- Head and neck cancer relapse after chemoradiotherapy correlates with CD163+ macrophages in primary tumour and CD11b+ myeloid cells in recurrences
- (2014) P Balermpas et al. BRITISH JOURNAL OF CANCER
- Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy
- (2014) Carola H. Ries et al. CANCER CELL
- Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
- (2014) Peter J. Murray et al. IMMUNITY
- Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation
- (2014) Jia Xue et al. IMMUNITY
- CCL3-CCR5 Axis Regulates Intratumoral Accumulation of Leukocytes and Fibroblasts and Promotes Angiogenesis in Murine Lung Metastasis Process
- (2014) Y. Wu et al. JOURNAL OF IMMUNOLOGY
- Chemokine expression profile of freshly isolated human glioblastoma-associated macrophages/microglia
- (2014) KIRSTEN HATTERMANN et al. ONCOLOGY REPORTS
- Serum CCL2 and CCL3 as potential biomarkers for the diagnosis of oral squamous cell carcinoma
- (2014) Liang Ding et al. TUMOR BIOLOGY
- A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients
- (2014) Meiying Zhang et al. Journal of Ovarian Research
- CCL2 Chemokine as a Potential Biomarker for Prostate Cancer: A Pilot Study
- (2014) Igor Tsaur et al. Cancer Research and Treatment
- CD163+ Tumor-Associated Macrophages Correlated with Poor Prognosis and Cancer Stem Cells in Oral Squamous Cell Carcinoma
- (2014) Ke-Fei He et al. Biomed Research International
- Role of tumor associated macrophages in tumor angiogenesis and lymphangiogenesis
- (2014) Vladimir Riabov et al. Frontiers in Physiology
- From Monocytes to M1/M2 Macrophages: Phenotypical vs. Functional Differentiation
- (2014) Paola Italiani et al. Frontiers in Immunology
- Pharmacological Inhibition of the Chemokine Receptor, CX3CR1, Reduces Atherosclerosis in Mice
- (2013) Lucie Poupel et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Correlations of Tumor-associated Macrophage Subtypes with Liver Metastases of Colorectal Cancer
- (2013) Yun-Long Cui et al. Asian Pacific Journal of Cancer Prevention
- Role of Macrophage Targeting in the Antitumor Activity of Trabectedin
- (2013) Giovanni Germano et al. CANCER CELL
- A first-in-human, first-in-class, phase I study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 in patients with solid tumors
- (2013) Shahneen K. Sandhu et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- A Phase I Study of an Agonist CD40 Monoclonal Antibody (CP-870,893) in Combination with Gemcitabine in Patients with Advanced Pancreatic Ductal Adenocarcinoma
- (2013) G. L. Beatty et al. CLINICAL CANCER RESEARCH
- Mixed-polarization phenotype of ascites-associated macrophages in human ovarian carcinoma: Correlation of CD163 expression, cytokine levels and early relapse
- (2013) Silke Reinartz et al. INTERNATIONAL JOURNAL OF CANCER
- IL-17 Stimulates Differentiation of Human Anti-Inflammatory Macrophages and Phagocytosis of Apoptotic Neutrophils in Response to IL-10 and Glucocorticoids
- (2013) G. Zizzo et al. JOURNAL OF IMMUNOLOGY
- Chemokine receptor CX3CR1 contributes to macrophage survival in tumor metastasis
- (2013) Jiao Zheng et al. Molecular Cancer
- Macrophage biology in development, homeostasis and disease
- (2013) Thomas A. Wynn et al. NATURE
- Microenvironmental regulation of tumor progression and metastasis
- (2013) Daniela F Quail et al. NATURE MEDICINE
- CSF-1R inhibition alters macrophage polarization and blocks glioma progression
- (2013) Stephanie M Pyonteck et al. NATURE MEDICINE
- Targeted delivery of proapoptotic peptides to tumor-associated macrophages improves survival
- (2013) M. Cieslewicz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phase I study of the CD40 agonist antibody CP-870,893 combined with carboplatin and paclitaxel in patients with advanced solid tumors
- (2013) Robert H. Vonderheide et al. OncoImmunology
- Recruitment of monocytes/macrophages in different tumor microenvironments
- (2012) Heon-Woo Lee et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Anti-tumor immune responses of tumor-associated macrophages via toll-like receptor 4 triggered by cationic polymers
- (2012) Zhen Huang et al. BIOMATERIALS
- The CD47–SIRPα pathway in cancer immune evasion and potential therapeutic implications
- (2012) Mark P Chao et al. CURRENT OPINION IN IMMUNOLOGY
- Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer
- (2012) Kenneth J. Pienta et al. INVESTIGATIONAL NEW DRUGS
- Macrophage plasticity and polarization: in vivo veritas
- (2012) Antonio Sica et al. JOURNAL OF CLINICAL INVESTIGATION
- Fibroblast Growth Factor Receptor 1 Activation in Mammary Tumor Cells Promotes Macrophage Recruitment in a CX3CL1-Dependent Manner
- (2012) Johanna R. Reed et al. PLoS One
- CCL2 increases MMP-9 expression and cell motility in human chondrosarcoma cells via the Ras/Raf/MEK/ERK/NF-κB signaling pathway
- (2011) Chih-Hsin Tang et al. BIOCHEMICAL PHARMACOLOGY
- Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer
- (2011) T. Shree et al. GENES & DEVELOPMENT
- Control of macrophage lineage populations by CSF-1 receptor and GM-CSF in homeostasis and inflammation
- (2011) Jason C Lenzo et al. IMMUNOLOGY AND CELL BIOLOGY
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- (2010) Bo Abrahamsen CURRENT OPINION IN RHEUMATOLOGY
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- (2010) Robert Sabat et al. CYTOKINE & GROWTH FACTOR REVIEWS
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- (2010) C. A. Gleissner et al. JOURNAL OF IMMUNOLOGY
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- (2007) Fernando Oneissi Martinez Frontiers in Bioscience-Landmark
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