Plant Derived Bioactive Compounds, Their Anti-Cancer Effects and In Silico Approaches as an Alternative Target Treatment Strategy for Breast Cancer: An Updated Overview
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Plant Derived Bioactive Compounds, Their Anti-Cancer Effects and In Silico Approaches as an Alternative Target Treatment Strategy for Breast Cancer: An Updated Overview
Authors
Keywords
-
Journal
Cancers
Volume 13, Issue 24, Pages 6222
Publisher
MDPI AG
Online
2021-12-13
DOI
10.3390/cancers13246222
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- CdO/CdCO3 nanocomposite physical properties and cytotoxicity against selected breast cancer cell lines
- (2021) R. P. Lefojane et al. Scientific Reports
- Pharmacological and Antioxidant Activities of Rhus coriaria L. (Sumac)
- (2021) Halima Alsamri et al. Antioxidants
- CHFR regulates chemoresistance in triple-negative breast cancer through destabilizing ZEB1
- (2021) Hong Luo et al. Cell Death & Disease
- Anticancer drug discovery from Iranian Chrysanthemum cultivars through system pharmacology exploration and experimental validation
- (2021) Mahboobeh Hodaei et al. Scientific Reports
- Inhibition of triple negative breast cancer metastasis and invasiveness by novel drugs that target epithelial to mesenchymal transition
- (2021) Elizabeth Garcia et al. Scientific Reports
- Systems Pharmacology-Based Precision Therapy and Drug Combination Discovery for Breast Cancer
- (2021) Ze-Jia Cui et al. Cancers
- A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein
- (2021) Pengyun Li et al. Cell Death Discovery
- Dissecting the biological heterogeneity of HER2-positive breast cancer
- (2021) Francesco Schettini et al. BREAST
- Asiatic Acid Interferes with Invasion and Proliferation of Breast Cancer Cells by Inhibiting WAVE3 Activation through PI3K/AKT Signaling Pathway
- (2020) Xiao-jun Gou et al. Biomed Research International
- LHRH-Conjugated Drugs as Targeted Therapeutic Agents for the Specific Targeting and Localized Treatment of Triple Negative Breast Cancer
- (2020) J. D. Obayemi et al. Scientific Reports
- Bacopa monnieri and Their Bioactive Compounds Inferred Multi-Target Treatment Strategy for Neurological Diseases: A Cheminformatics and System Pharmacology Approach
- (2020) Rajendran Jeyasri et al. Biomolecules
- In Vitro Propagation, Phytochemical and Neuropharmacological Profiles of Bacopa monnieri (L.) Wettst.: A Review
- (2020) Partha Sarathi Saha et al. Plants-Basel
- Quantitative Systems Pharmacology approaches for Immuno‐oncology: adding virtual patients to the development paradigm
- (2020) Vijayalakshmi Chelliah et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Anti-proliferative Efficiency of Pulsed Electric Field Treated Curcuma Longa (Turmeric) Extracts on Breast Cancer Cell Lines
- (2020) S. Poompavai et al. IETE JOURNAL OF RESEARCH
- The Essential Oil of Cymbopogon citratus Stapt and Carvacrol: An Approach of the Antitumor Effect on 7,12-Dimethylbenz-[α]-anthracene (DMBA)-Induced Breast Cancer in Female Rats
- (2020) Juan Pedro Rojas-Armas et al. MOLECULES
- Nephronectin promotes breast cancer brain metastatic colonization via its integrin-binding domains
- (2020) Synnøve Norvoll Magnussen et al. Scientific Reports
- Evaluations of biosynthesized Ag nanoparticles via Allium Sativum flower extract in biological applications
- (2020) K. Velsankar et al. Applied Nanoscience
- Recent progress on cheminformatics approaches to epigenetic drug discovery
- (2020) Zoe Sessions et al. DRUG DISCOVERY TODAY
- Echinacea Angustifolia DC Extract Induces Apoptosis and Cell Cycle Arrest and Synergizes with Paclitaxel in the MDA-MB-231 and MCF-7 Human Breast Cancer Cell Lines
- (2020) Daniel Abraham Espinosa-Paredes et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Roles of plant‐derived bioactive compounds and related microRNAs in cancer therapy
- (2020) Heng Zou et al. PHYTOTHERAPY RESEARCH
- Identification of key genes unique to the luminal a and basal-like breast cancer subtypes via bioinformatic analysis
- (2020) Rong Jia et al. World Journal of Surgical Oncology
- FBI-1 enhanced the resistance of triple-negative breast cancer cells to chemotherapeutic agents via the miR-30c/PXR axis
- (2020) Hua Yang et al. Cell Death & Disease
- A network pharmacology-based approach to explore potential targets of Caesalpinia pulcherima: an updated prototype in drug discovery
- (2020) Nikhil S. Sakle et al. Scientific Reports
- Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
- (2020) Peter Kubatka et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- HIF1A signaling selectively supports proliferation of breast cancer in the brain
- (2020) Richard Y. Ebright et al. Nature Communications
- Cheminformatics to Characterize Pharmacologically Active Natural Products
- (2020) José L. Medina-Franco et al. Biomolecules
- Plant Phenolics: Bioavailability as a Key Determinant of Their Potential Health-Promoting Applications
- (2020) Patricia Cosme et al. Antioxidants
- In vitro cytotoxicity and anticancer effects of citral nanostructured lipid carrier on MDA MBA-231 human breast cancer cells
- (2019) Noraini Nordin et al. Scientific Reports
- ADMET modeling approaches in drug discovery
- (2019) Leonardo L.G. Ferreira et al. DRUG DISCOVERY TODAY
- Targeting the PI3-kinase pathway in triple-negative breast cancer
- (2019) J Pascual et al. ANNALS OF ONCOLOGY
- Computer-Assisted Drug Virtual Screening Based on the Natural Product Databases
- (2019) Baoyu Yang et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- Radiosensitizing effect of curcumin-loaded lipid nanoparticles in breast cancer cells
- (2019) Luigi Minafra et al. Scientific Reports
- Discovery of the Anti-Tumor Mechanism of Calycosin Against Colorectal Cancer by Using System Pharmacology Approach
- (2019) Chen Huang et al. MEDICAL SCIENCE MONITOR
- Bioactive Compounds and Bioactivities of Ginger (Zingiber officinale Roscoe)
- (2019) Qian-Qian Mao et al. Foods
- Bioactive Compounds and Biological Functions of Garlic (Allium sativum L.)
- (2019) Shang et al. Foods
- A drug-likeness toolbox facilitates ADMET study in drug discovery
- (2019) Chen-Yang Jia et al. DRUG DISCOVERY TODAY
- GATA3 recruits UTX for gene transcriptional activation to suppress metastasis of breast cancer
- (2019) Wenqian Yu et al. Cell Death & Disease
- Ricinus communis L. fruit extract inhibits migration/invasion, induces apoptosis in breast cancer cells and arrests tumor progression in vivo
- (2019) Munmi Majumder et al. Scientific Reports
- Bioactive Compounds: Natural Defense Against Cancer?
- (2019) Shonia Subramaniam et al. Biomolecules
- A novel panel of differentially-expressed microRNAs in breast cancer brain metastasis may predict patient survival
- (2019) Athina Giannoudis et al. Scientific Reports
- Anticancer Plants: A Review of the Active Phytochemicals, Applications in Animal Models, and Regulatory Aspects
- (2019) Tariq Khan et al. Biomolecules
- Therapeutic role of Ricinus communis L. and its bioactive compounds in disease prevention and treatment
- (2018) WaseemMohammed Abdul et al. Asian Pacific Journal of Tropical Medicine
- ZEB1 confers chemotherapeutic resistance to breast cancer by activating ATM
- (2018) Xiang Zhang et al. Cell Death & Disease
- IMPPAT: A curated database of Indian Medicinal Plants, Phytochemistry And Therapeutics
- (2018) Karthikeyan Mohanraj et al. Scientific Reports
- The antipsychotic agent trifluoperazine hydrochloride suppresses triple-negative breast cancer tumor growth and brain metastasis by inducing G0/G1 arrest and apoptosis
- (2018) Zhanzhan Feng et al. Cell Death & Disease
- Accelerating pharmaceutical structure-guided drug design: a successful model
- (2018) Lisa J. Keefe et al. DRUG DISCOVERY TODAY
- SymMap: an integrative database of traditional Chinese medicine enhanced by symptom mapping
- (2018) Yang Wu et al. NUCLEIC ACIDS RESEARCH
- CMAUP: a database of collective molecular activities of useful plants
- (2018) Xian Zeng et al. NUCLEIC ACIDS RESEARCH
- Synthesis and characterization of Zinc oxide nanoparticles utilizing seed source of Ricinus communis and study of its antioxidant, antifungal and anticancer activity
- (2018) N. Shobha et al. Materials Science & Engineering C-Materials for Biological Applications
- Regulation of MicroRNAs by Natural Products and Bioactive Compounds Obtained From Common Medicinal Plants: Novel Strategy in Cancer Therapy
- (2017) Sevgi Gezici et al. Indian Journal of Pharmaceutical Education and Research
- Systems Pharmacology Dissection of Multiscale Mechanisms of Action for Herbal Medicines in Treating Rheumatoid Arthritis
- (2017) Jinghui Wang et al. MOLECULAR PHARMACEUTICS
- Emerging Cytotoxic Alkaloids in the Battle against Cancer: Overview of Molecular Mechanisms
- (2017) Zeina Habli et al. MOLECULES
- Application of pharmacometrics and quantitative systems pharmacology to cancer therapy: The example of luminal a breast cancer
- (2017) Brett Fleisher et al. PHARMACOLOGICAL RESEARCH
- A Methodology for Cancer Therapeutics by Systems Pharmacology-Based Analysis: A Case Study on Breast Cancer-Related Traditional Chinese Medicines
- (2017) Yan Li et al. PLoS One
- Molecular characterization of breast cancer CTCs associated with brain metastasis
- (2017) Debasish Boral et al. Nature Communications
- Dietary Natural Products for Prevention and Treatment of Breast Cancer
- (2017) Ya Li et al. Nutrients
- Costunolide and dehydrocostuslactone combination treatment inhibit breast cancer by inducing cell cycle arrest and apoptosis through c-Myc/p53 and AKT/14-3-3 pathway
- (2017) Zhangxiao Peng et al. Scientific Reports
- Enhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine
- (2017) Justine M. Grixti et al. Frontiers in Pharmacology
- System Pharmacology-Based Dissection of the Synergistic Mechanism of Huangqi and Huanglian for Diabetes Mellitus
- (2017) Shi-Jun Yue et al. Frontiers in Pharmacology
- Cancer prevention from the perspective of global cancer burden patterns
- (2017) Hiroki Nagai et al. Journal of Thoracic Disease
- New insights on PI3K/AKT pathway alterations and clinical outcomes in breast cancer
- (2016) Sherry X. Yang et al. CANCER TREATMENT REVIEWS
- Arctigenin, a lignan from Arctium lappa L., inhibits metastasis of human breast cancer cells through the downregulation of MMP-2/−9 and heparanase in MDA-MB-231 cells
- (2016) Chenghua Lou et al. ONCOLOGY REPORTS
- Natural cures for breast cancer treatment
- (2016) Munazza Shareef et al. SAUDI PHARMACEUTICAL JOURNAL
- KHF16 is a Leading Structure from Cimicifuga foetida that Suppresses Breast Cancer Partially by Inhibiting the NF-κB Signaling Pathway
- (2016) Yanjie Kong et al. Theranostics
- The hedgehog pathway in triple-negative breast cancer
- (2016) Joyce G. Habib et al. Cancer Medicine
- Rhus coriaria suppresses angiogenesis, metastasis and tumor growth of breast cancer through inhibition of STAT3, NFκB and nitric oxide pathways
- (2016) Hussain El Hasasna et al. Scientific Reports
- Growth inhibition and apoptosis in cancer cells induced by polyphenolic compounds of Acacia hydaspica: Involvement of multiple signal transduction pathways
- (2016) Tayyaba Afsar et al. Scientific Reports
- A triterpenoid from wild bitter gourd inhibits breast cancer cells
- (2016) Li-Yuan Bai et al. Scientific Reports
- New potential beneficial effects of actein, a triterpene glycoside isolated from Cimicifuga species, in breast cancer treatment
- (2016) Grace Gar-Lee Yue et al. Scientific Reports
- The anti-cancer effects of carotenoids and other phytonutrients resides in their combined activity
- (2015) Karin Linnewiel-Hermoni et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- An overview of triple-negative breast cancer
- (2015) Pankaj Kumar et al. ARCHIVES OF GYNECOLOGY AND OBSTETRICS
- European Code against Cancer 4th Edition: Physical activity and cancer
- (2015) Michael Leitzmann et al. Cancer Epidemiology
- Molecular Modeling Based Synthesis and Evaluation of In vitro Anticancer Activity of Indolyl Chalcones
- (2015) Rashmi Gaur et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Anti-breast tumor activity of Eclipta extract in-vitro and in-vivo: novel evidence of endoplasmic reticulum specific localization of Hsp60 during apoptosis
- (2015) Rakesh K. Arya et al. Scientific Reports
- Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation
- (2015) Hussain El Hasasna et al. Scientific Reports
- Fascin is involved in the chemotherapeutic resistance of breast cancer cells predominantly via the PI3K/Akt pathway
- (2014) H Ghebeh et al. BRITISH JOURNAL OF CANCER
- Targeting the PI3K/AKT/mTOR pathway in estrogen receptor-positive breast cancer
- (2014) Eva Maria Ciruelos Gil CANCER TREATMENT REVIEWS
- Activation of intrinsic apoptotic signaling pathway in cancer cells by Cymbopogon citratus polysaccharide fractions
- (2014) Ramar Thangam et al. CARBOHYDRATE POLYMERS
- Basal-Like and Triple-Negative Breast Cancers
- (2014) Prasanna Alluri et al. Surgical Oncology Clinics of North America
- Evaluating Medicinal Plants for Anticancer Activity
- (2014) Elisha Solowey et al. TheScientificWorldJOURNAL
- The Wedelolactone Derivative Inhibits Estrogen Receptor-Mediated Breast, Endometrial, and Ovarian Cancer Cells Growth
- (2014) Defeng Xu et al. Biomed Research International
- The PI3K/AKT/mTOR pathway in breast cancer: targets, trials and biomarkers
- (2014) Elisavet Paplomata et al. Therapeutic Advances in Medical Oncology
- The Wnt signalling pathway is upregulated in an in vitro model of acquired tamoxifen resistant breast cancer
- (2013) Yan Ni Loh et al. BMC CANCER
- New Perspectives on How to Discover Drugs from Herbal Medicines: CAM's Outstanding Contribution to Modern Therapeutics
- (2013) Si-Yuan Pan et al. Evidence-based Complementary and Alternative Medicine
- Saussurea lappaClarke-Derived Costunolide Prevents TNFα-Induced Breast Cancer Cell Migration and Invasion by Inhibiting NF-κB Activity
- (2013) Youn Kyung Choi et al. Evidence-based Complementary and Alternative Medicine
- Breast cancer as a systemic disease: a view of metastasis
- (2013) A. J. Redig et al. JOURNAL OF INTERNAL MEDICINE
- Lappaol F, a Novel Anticancer Agent Isolated from Plant Arctium Lappa L.
- (2013) Q. Sun et al. MOLECULAR CANCER THERAPEUTICS
- Bioinformatics opportunities for identification and study of medicinal plants
- (2012) V. Sharma et al. BRIEFINGS IN BIOINFORMATICS
- Frequent Mutational Activation of the PI3K-AKT Pathway in Trastuzumab-Resistant Breast Cancer
- (2012) S. Chandarlapaty et al. CLINICAL CANCER RESEARCH
- Targeting the PI3K/Akt/mTOR Pathway for Breast Cancer Therapy
- (2012) Justin Cidado et al. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
- Keratin expression in breast cancers
- (2012) Mu-Min Shao et al. VIRCHOWS ARCHIV
- Apoptosis induction of Centella asiatica on human breast cancer cells
- (2011) S Babykutty et al. African Journal of Traditional Complementary and Alternative Medicines
- RETRACTED ARTICLE: In vitro antioxidant and anticancer activity of young Zingiber officinale against human breast carcinoma cell lines
- (2011) Shahedur Rahman et al. BMC Complementary and Alternative Medicine
- Subtype-specific alterations of the Wnt signaling pathway in breast cancer: Clinical and prognostic significance
- (2011) Nupur Mukherjee et al. CANCER SCIENCE
- Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells
- (2010) Mahvash Zakikhani et al. BREAST CANCER RESEARCH AND TREATMENT
- Hedgehog signaling pathway mediates the progression of non-invasive breast cancer to invasive breast cancer
- (2010) Masae Souzaki et al. CANCER SCIENCE
- Through a Glass Darkly: Advances in Understanding Breast Cancer Biology, 2000–2010
- (2010) Lisa A. Carey Clinical Breast Cancer
- Triple-Negative Breast Cancer: Distinguishing between Basal and Nonbasal Subtypes
- (2009) E. A. Rakha et al. CLINICAL CANCER RESEARCH
- PI3K pathway activation in breast cancer is associated with the basal-like phenotype and cancer-specific mortality
- (2009) Elena López-Knowles et al. INTERNATIONAL JOURNAL OF CANCER
- Antioxidant and Cytotoxic Activities of Centella asiatica (L) Urb.
- (2009) Frederico Pittella et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Inhibitors of the PI3K/Akt/mTOR Pathway: New Hope for Breast Cancer Patients
- (2009) Sandra Ghayad et al. Recent Patents on Anti-Cancer Drug Discovery
- A new sesquiterpene lactone from the roots of Saussurea lappa: Structure–anticancer activity study
- (2008) A. Robinson et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now