- Home
- Publications
- Publication Search
- Publication Details
Title
RAD52: Paradigm of Synthetic Lethality and New Developments
Authors
Keywords
-
Journal
Frontiers in Genetics
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-11-30
DOI
10.3389/fgene.2021.780293
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- RADX controls RAD51 filament dynamics to regulate replication fork stability
- (2021) Madison B. Adolph et al. MOLECULAR CELL
- RAD52 Adjusts Repair of Single-Strand Breaks via Reducing DNA-Damage-Promoted XRCC1/LIG3α Co-localization
- (2021) Jian Wang et al. Cell Reports
- Altered DNA repair creates novel Alu/Alu repeat‐mediated deletions
- (2021) Maria E. Morales et al. HUMAN MUTATION
- Single-Strand Annealing in Cancer
- (2021) Janusz Blasiak INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Repair of DNA Breaks by Break-Induced Replication
- (2021) Z.W. Kockler et al. Annual Review of Biochemistry
- Shaping the BRCAness mutational landscape by alternative double-strand break repair, replication stress and mitotic aberrancies
- (2021) Colin Stok et al. NUCLEIC ACIDS RESEARCH
- XAB2 promotes Ku eviction from single-ended DNA double-strand breaks independently of the ATM kinase
- (2021) Abhishek Bharadwaj Sharma et al. NUCLEIC ACIDS RESEARCH
- Nonhomologous end joining: new accessory factors fine tune the machinery
- (2021) Dipayan Ghosh et al. TRENDS IN GENETICS
- Polθ reverse transcribes RNA and promotes RNA-templated DNA repair
- (2021) Gurushankar Chandramouly et al. Science Advances
- POLθ-mediated end joining is restricted by RAD52 and BRCA2 until the onset of mitosis
- (2021) Marta Llorens-Agost et al. NATURE CELL BIOLOGY
- The Safe Path at the Fork: Ensuring Replication-Associated DNA Double-Strand Breaks are Repaired by Homologous Recombination
- (2021) Jac A. Nickoloff et al. Frontiers in Genetics
- Aberrant Expression of RAD52, Its Prognostic Impact in Rectal Cancer and Association with Poor Survival of Patients
- (2020) Vincent Ho et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Phosphoregulation of Rad51/Rad52 by CDK1 functions as a molecular switch for cell cycle–specific activation of homologous recombination
- (2020) Gyubum Lim et al. Science Advances
- RAD52: Viral Friend or Foe?
- (2020) Eric A. Hendrickson Cancers
- RAD52 S346X variant reduces breast cancer risk in BRCA2 mutation carriers
- (2020) Kajal Biswas et al. Molecular Oncology
- The RAD52 S346X variant reduces risk of developing breast cancer in carriers of pathogenic germline BRCA2 mutations
- (2020) Aaron W. Adamson et al. Molecular Oncology
- Current Understanding of RAD52 Functions: Fundamental and Therapeutic Insights
- (2020) Vanesa Gottifredi et al. Cancers
- The MRE11 complex: A versatile toolkit for the repair of broken DNA
- (2020) Giordano Reginato et al. DNA REPAIR
- Mechanism and significance of chromosome damage repair by homologous recombination
- (2020) Ajinkya S. Kawale et al. Essays in Biochemistry
- Replication protein A binds RNA and promotes R-loop formation
- (2020) Olga M Mazina et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RAD52 aptamer regulates DNA damage repair and STAT3 in BRCA1/BRCA2‑deficient human acute myeloid leukemia
- (2020) Yichuan Xu et al. ONCOLOGY REPORTS
- m5C modification of mRNA serves a DNA damage code to promote homologous recombination
- (2020) Hao Chen et al. Nature Communications
- Genetic Characterization of Three Distinct Mechanisms Supporting RNA-Driven DNA Repair and Modification Reveals Major Role of DNA Polymerase ζ
- (2020) Chance Meers et al. MOLECULAR CELL
- Making choices: DNA replication fork recovery mechanisms
- (2020) Christine M. Kondratick et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- A Rad51-independent pathway promotes single-strand template repair in gene editing
- (2020) Danielle N. Gallagher et al. PLoS Genetics
- Under-Replicated DNA: The Byproduct of Large Genomes?
- (2020) Agustina P. Bertolin et al. Cancers
- Non‐recombinogenic roles for Rad52 in translesion synthesis during DNA damage tolerance
- (2020) María I Cano‐Linares et al. EMBO REPORTS
- The function of RAD52 N-terminal domain is essential for viability of BRCA-deficient cells
- (2020) Kritika Hanamshet et al. NUCLEIC ACIDS RESEARCH
- Alternative Lengthening of Telomeres through Two Distinct Break-Induced Replication Pathways
- (2019) Jia-Min Zhang et al. Cell Reports
- 53BP1 nuclear bodies enforce replication timing at under-replicated DNA to limit heritable DNA damage
- (2019) Julian Spies et al. NATURE CELL BIOLOGY
- Human DNA polymerase η has reverse transcriptase activity in cellular environments
- (2019) Yan Su et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RAD52 and SLX4 act nonepistatically to ensure telomere stability during alternative telomere lengthening
- (2019) Priyanka Verma et al. GENES & DEVELOPMENT
- DNA double-strand break repair-pathway choice in somatic mammalian cells
- (2019) Ralph Scully et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks
- (2019) Judit Domingo-Prim et al. Nature Communications
- Emerging Roles of RAD52 in Genome Maintenance
- (2019) Manisha Jalan et al. Cancers
- MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers
- (2019) Gayathri Srinivasan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human RECQL4 represses the RAD52‐mediated single‐strand annealing pathway after ionizing radiation or cisplatin treatment
- (2019) Masaoki Kohzaki et al. INTERNATIONAL JOURNAL OF CANCER
- Synthetic lethality as an engine for cancer drug target discovery
- (2019) Alan Huang et al. NATURE REVIEWS DRUG DISCOVERY
- An R-loop-initiated CSB–RAD52–POLD3 pathway suppresses ROS-induced telomeric DNA breaks
- (2019) Jun Tan et al. NUCLEIC ACIDS RESEARCH
- Non-enzymatic roles of human RAD51 at stalled replication forks
- (2019) Jennifer M. Mason et al. Nature Communications
- DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G2-checkpoint in S-phase irradiated cells
- (2019) Emil Mladenov et al. Scientific Reports
- RAD52 as a Potential Target for Synthetic Lethality-Based Anticancer Therapies
- (2019) Toma et al. Cancers
- RAD52 Functions in Homologous Recombination and Its Importance on Genomic Integrity Maintenance and Cancer Therapy
- (2019) Augusto Nogueira et al. Cancers
- Strong suppression of gene conversion with increasing DNA double-strand break load delimited by 53BP1 and RAD52
- (2019) Emil Mladenov et al. NUCLEIC ACIDS RESEARCH
- DSS1 interacts with and stimulates RAD52 to promote the repair of DSBs
- (2019) Barbora Stefanovie et al. NUCLEIC ACIDS RESEARCH
- ATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress
- (2019) Su Hyung Park et al. Nature Communications
- From “Cellular” RNA to “Smart” RNA: Multiple Roles of RNA in Genome Stability and Beyond
- (2018) Flavia Michelini et al. CHEMICAL REVIEWS
- How RNA transcripts coordinate DNA recombination and repair
- (2018) Shane McDevitt et al. Nature Communications
- Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells
- (2018) Katherine Sullivan-Reed et al. Cell Reports
- Novel function of HATs and HDACs in homologous recombination through acetylation of human RAD52 at double-strand break sites
- (2018) Takeshi Yasuda et al. PLoS Genetics
- Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair
- (2018) Takaaki Yasuhara et al. CELL
- Mechanisms of PARP inhibitor sensitivity and resistance
- (2018) Alan D. D’Andrea DNA REPAIR
- RNF169 limits 53BP1 deposition at DSBs to stimulate single-strand annealing repair
- (2018) Liwei An et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ATM in breast and brain tumors: a comprehensive review
- (2018) Asghari Estiar Mehrdad et al. Cancer Biology & Medicine
- ROS-induced R loops trigger a transcription-coupled but BRCA1/2-independent homologous recombination pathway through CSB
- (2018) Yaqun Teng et al. Nature Communications
- The DNA damage response pathway in normal hematopoiesis and malignancies
- (2017) Domenico Delia et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Human RAD52 interactions with replication protein A and the RAD51 presynaptic complex
- (2017) Chu Jian Ma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RAD52 is required for RNA-templated recombination repair in post-mitotic neurons
- (2017) Starr Welty et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks
- (2017) Hyun-Suk Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
- (2017) Hai Dang Nguyen et al. MOLECULAR CELL
- Rad52 Inverse Strand Exchange Drives RNA-Templated DNA Double-Strand Break Repair
- (2017) Olga M. Mazina et al. MOLECULAR CELL
- Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers
- (2017) Angelo Taglialatela et al. MOLECULAR CELL
- Non-homologous DNA end joining and alternative pathways to double-strand break repair
- (2017) Howard H. Y. Chang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- PARP inhibitors: Synthetic lethality in the clinic
- (2017) Christopher J. Lord et al. SCIENCE
- MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells
- (2017) Delphine Lemaçon et al. Nature Communications
- Replication fork reversal triggers fork degradation in BRCA2-defective cells
- (2017) Sofija Mijic et al. Nature Communications
- Rad52 deficiency decreases development of lung squamous cell carcinomas by enhancing immuno-surveillance
- (2017) Rachel Lieberman et al. Oncotarget
- S1-DRIP-seq identifies high expression and polyA tracts as major contributors to R-loop formation
- (2016) Lamia Wahba et al. GENES & DEVELOPMENT
- Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks
- (2016) Sotirios K. Sotiriou et al. MOLECULAR CELL
- Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing
- (2016) Panagiotis Galanos et al. NATURE CELL BIOLOGY
- 53BP1 fosters fidelity of homology-directed DNA repair
- (2016) Fena Ochs et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Targeting BRCA1- and BRCA2-deficient cells with RAD52 small molecule inhibitors
- (2016) Fei Huang et al. NUCLEIC ACIDS RESEARCH
- Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection
- (2016) Katherine Sullivan et al. PLoS One
- Roles of C-Terminal Region of Yeast and Human Rad52 in Rad51-Nucleoprotein Filament Formation and ssDNA Annealing
- (2016) Nilesh V. Khade et al. PLoS One
- Inevitability and containment of replication errors for eukaryotic genome lengths spanning megabase to gigabase
- (2016) Mohammed Al Mamun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Repair Pathway Choices and Consequences at the Double-Strand Break
- (2016) Raphael Ceccaldi et al. TRENDS IN CELL BIOLOGY
- Regulation of Single-Strand Annealing and its Role in Genome Maintenance
- (2016) Ragini Bhargava et al. TRENDS IN GENETICS
- Nascent Connections: R-Loops and Chromatin Patterning
- (2016) Frédéric Chédin TRENDS IN GENETICS
- 53BP1 fosters fidelity of homology-directed DNA repair
- (2016) Fena Ochs et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cells
- (2016) Sarah R Hengel et al. eLife
- Reappearance from Obscurity: Mammalian Rad52 in Homologous Recombination
- (2016) Kritika Hanamshet et al. Genes
- Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers
- (2015) Gurushankar Chandramouly et al. CHEMISTRY & BIOLOGY
- Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells
- (2015) Ralph Zellweger et al. JOURNAL OF CELL BIOLOGY
- Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry
- (2015) Weixing Zhao et al. MOLECULAR CELL
- Replication fork reversal in eukaryotes: from dead end to dynamic response
- (2015) Kai J. Neelsen et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination
- (2015) Leizhen Wei et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Overview of the Molecular Mechanisms of Recombinational DNA Repair
- (2015) Stephen C. Kowalczykowski Cold Spring Harbor Perspectives in Biology
- Transcript-RNA-templated DNA recombination and repair
- (2014) Havva Keskin et al. NATURE
- Protein dynamics during presynaptic-complex assembly on individual single-stranded DNA molecules
- (2014) Bryan Gibb et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mediators of Homologous DNA Pairing
- (2014) A. Zelensky et al. Cold Spring Harbor Perspectives in Biology
- Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile
- (2013) K. Cramer-Morales et al. BLOOD
- Break-induced replication: functions and molecular mechanism
- (2013) Anna Malkova et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration
- (2013) Marenda A. Wilson et al. NATURE
- Mechanisms of resistance to therapies targeting BRCA-mutant cancers
- (2013) Christopher J Lord et al. NATURE MEDICINE
- The ATM protein kinase: regulating the cellular response to genotoxic stress and more
- (2013) Yosef Shiloh et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Break-Induced Replication Repair of Damaged Forks Induces Genomic Duplications in Human Cells
- (2013) Lorenzo Costantino et al. SCIENCE
- Survival of the Replication Checkpoint Deficient Cells Requires MUS81-RAD52 Function
- (2013) Ivana Murfuni et al. PLoS Genetics
- Rad51 Paralog Complexes BCDX2 and CX3 Act at Different Stages in the BRCA1-BRCA2-Dependent Homologous Recombination Pathway
- (2012) J. Chun et al. MOLECULAR AND CELLULAR BIOLOGY
- RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2 in addition to BRCA2 through RAD51-mediated homologous recombination
- (2012) B H Lok et al. ONCOGENE
- Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding
- (2011) Masayoshi Honda et al. EMBO JOURNAL
- Collisions between Replication and Transcription Complexes Cause Common Fragile Site Instability at the Longest Human Genes
- (2011) Anne Helmrich et al. MOLECULAR CELL
- 53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress
- (2011) Claudia Lukas et al. NATURE CELL BIOLOGY
- Break-Induced Replication Is Highly Inaccurate
- (2011) Angela Deem et al. PLOS BIOLOGY
- Break-induced replication: What is it and what is it for?
- (2010) Bertrand Llorente et al. CELL CYCLE
- Patterns of Expression of DNA Repair Genes and Relapse From Melanoma
- (2010) R. Jewell et al. CLINICAL CANCER RESEARCH
- Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA
- (2010) Jie Liu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cooperation of RAD51 and RAD54 in regression of a model replication fork
- (2010) Dmitry V. Bugreev et al. NUCLEIC ACIDS RESEARCH
- Rad52 inactivation is synthetically lethal with BRCA2 deficiency
- (2010) Z. Feng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DNA Damage, Aging, and Cancer
- (2009) Jan H.J. Hoeijmakers NEW ENGLAND JOURNAL OF MEDICINE
- Identification of a Second DNA Binding Site in the Human Rad52 Protein
- (2008) Wataru Kagawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started