RAD52 Functions in Homologous Recombination and Its Importance on Genomic Integrity Maintenance and Cancer Therapy

Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells

(2018) Katherine Sullivan-Reed et al.   Cell Reports

Synthetic lethality in DNA repair network: A novel avenue in targeted cancer therapy and combination therapeutics

(2017) Sonali Bhattacharjee et al.   IUBMB LIFE

Tumor microenvironment and cancer therapy resistance

(2016) Yu Sun   CANCER LETTERS

Targeting BRCA1- and BRCA2-deficient cells with RAD52 small molecule inhibitors

(2016) Fei Huang et al.   NUCLEIC ACIDS RESEARCH

Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection

(2016) Katherine Sullivan et al.   PLoS One

Reappearance from Obscurity: Mammalian Rad52 in Homologous Recombination

(2016) Kritika Hanamshet et al.   Genes

The DNA Damage Response: Implications for Tumor Responses to Radiation and Chemotherapy

(2015) Michael Goldstein et al.   Annual Review of Medicine

DNA damage response – A double-edged sword in cancer prevention and cancer therapy

(2015) Hui Tian et al.   CANCER LETTERS

Functional characterization of RAD52 as a lung cancer susceptibility gene in the 12p13.33 locus

(2015) Rachel Lieberman et al.   MOLECULAR CARCINOGENESIS

Pharmacogenetics of DNA repair gene polymorphisms in non-small-cell lung carcinoma patients on platinum-based chemotherapy

(2014) L. Zhang et al.   GENETICS AND MOLECULAR RESEARCH

Molecular aspects of cancer cell resistance to chemotherapy

(2013) Magali Rebucci et al.   BIOCHEMICAL PHARMACOLOGY

Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile

(2013) K. Cramer-Morales et al.   BLOOD

Chromatin PTEN is involved in DNA damage response partly through regulating Rad52 sumoylation

(2013) Byeong Choi et al.   CELL CYCLE

Molecular Pathways: Understanding the Role of Rad52 in Homologous Recombination for Therapeutic Advancement

(2012) B. H. Lok et al.   CLINICAL CANCER RESEARCH

The DNA damage response and cancer therapy

(2012) Christopher J. Lord et al.   NATURE

RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2 in addition to BRCA2 through RAD51-mediated homologous recombination

(2012) B H Lok et al.   ONCOGENE

RAD52 Variants Predict Platinum Resistance and Prognosis of Cervical Cancer

(2012) Ting-Yan Shi et al.   PLoS One

Synthetic lethality: exploiting the addiction of cancer to DNA repair

(2011) M. Shaheen et al.   BLOOD

Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding

(2011) Masayoshi Honda et al.   EMBO JOURNAL

Role of Rad52 in fractionated irradiation induced signaling in A549 lung adenocarcinoma cells

(2011) Somnath Ghosh et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Genomic instability and cancer: an introduction

(2011) Z. Shen   Journal of Molecular Cell Biology

Inherited Variation at Chromosome 12p13.33, Including RAD52 , Influences the Risk of Squamous Cell Lung Carcinoma

(2011) Jianxin Shi et al.   Cancer Discovery

Regulation of Homologous Recombination in Eukaryotes

(2010) Wolf-Dietrich Heyer et al.   Annual Review of Genetics

Break-induced replication: What is it and what is it for?

(2010) Bertrand Llorente et al.   CELL CYCLE

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

(2010) Mary Ellen Moynahan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rad52 SUMOylation affects the efficiency of the DNA repair

(2010) Veronika Altmannova et al.   NUCLEIC ACIDS RESEARCH

Rad52 inactivation is synthetically lethal with BRCA2 deficiency

(2010) Z. Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Timing is everything: cell cycle control of Rad52

(2010) Jacqueline H Barlow et al.   Cell Division

Mechanisms of double-strand break repair in somatic mammalian cells

(2009) Andrea J. Hartlerode et al.   BIOCHEMICAL JOURNAL

PALB2 Links BRCA1 and BRCA2 in the DNA-Damage Response

(2009) Feng Zhang et al.   CURRENT BIOLOGY

Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2

(2009) H Christian Reinhardt et al.   CURRENT OPINION IN CELL BIOLOGY

Inhibition of Poly(ADP-Ribose) Polymerase in Tumors fromBRCAMutation Carriers

(2009) Peter C. Fong et al.   NEW ENGLAND JOURNAL OF MEDICINE

DNA Damage, Aging, and Cancer

(2009) Jan H.J. Hoeijmakers   NEW ENGLAND JOURNAL OF MEDICINE

PALB2 is an integral component of the BRCA complex required for homologous recombination repair

(2009) S. M. H. Sy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding DNA Damage Response and DNA Repair Pathways: Applications to More Targeted Cancer Therapeutics

(2009) Timothy J. Kinsella   SEMINARS IN ONCOLOGY

Mechanism of Eukaryotic Homologous Recombination

(2008) Joseph San Filippo et al.   Annual Review of Biochemistry

Rad52 sumoylation and its involvement in the efficient induction of homologous recombination

(2008) Takashi Ohuchi et al.   DNA REPAIR

DNA Repair Synthesis Facilitates RAD52-Mediated Second-End Capture during DSB Repair

(2008) Michael J. McIlwraith et al.   MOLECULAR CELL

Differential Regulation of the Cellular Response to DNA Double-Strand Breaks in G1

(2008) Jacqueline H. Barlow et al.   MOLECULAR CELL