Double Asymmetric Hydrogenation of α-Iminoketones: Facile Synthesis of Enantiopure Vicinal Amino Alcohols

Catalytic Diastereo‐ and Enantioconvergent Synthesis of Vicinal Diamines from Diols through Borrowing Hydrogen

(2021) Hui‐Jie Pan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Concise, scalable and enantioselective total synthesis of prostaglandins

(2021) Fuhao Zhang et al.   Nature Chemistry

Rh-Catalyzed Asymmetric Hydrogenation of Unsaturated Medium-Ring NH Lactams: Highly Enantioselective Synthesis of N-Unprotected 2,3-Dihydro-1,5-benzothiazepinones

(2020) Congcong Yin et al.   ORGANIC LETTERS

Facile Synthesis of Enantiopure Sugar Alcohols Enabled by Asymmetric Hydrogenation via Dynamic Kinetic Resolution

(2020) Jiang Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Noncovalent Interaction-Assisted Ferrocenyl Phosphine Ligands in Asymmetric Catalysis

(2020) Qingyang Zhao et al.   ACCOUNTS OF CHEMICAL RESEARCH

Iridium-Catalyzed Asymmetric Hydrogenation of α-Fluoro Ketones via a Dynamic Kinetic Resolution Strategy

(2020) Xuefeng Tan et al.   ORGANIC LETTERS

Phosphorus Ligands from the Zhang lab: Design, Asymmetric Hydrogenation, and Industrial Applications

(2020) Feng Wan et al.   CHINESE JOURNAL OF CHEMISTRY

Highly Chemo- and Enantioselective Rh-Catalyzed Hydrogenation of β-Sulfonyl-α,β-unsaturated Ketones: Access to Chiral γ-Ketosulfones

(2020) Gang Liu et al.   ORGANIC LETTERS

Direct Conversion of Primary Alcohols to 1,2-Amino Alcohols: Enantioselective Iridium-Catalyzed Carbonyl Reductive Coupling of Phthalimido-Allene via Hydrogen Auto-Transfer

(2019) Kim Spielmann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design and Synthesis of Chiral oxa-Spirocyclic Ligands for Ir-Catalyzed Direct Asymmetric Reduction of Bringmann’s Lactones with Molecular H2

(2018) Gen-Qiang Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective and Diastereoselective Ir-Catalyzed Hydrogenation of α-Substituted β-Ketoesters via Dynamic Kinetic Resolution

(2018) Guoxian Gu et al.   ORGANIC LETTERS

Brønsted-Acid-Promoted Rh-Catalyzed Asymmetric Hydrogenation of N-Unprotected Indoles: A Cocatalysis of Transition Metal and Anion Binding

(2018) Jialin Wen et al.   ORGANIC LETTERS

Selective synthesis of 1,4,5-trisubstituted imidazoles from α -imino ketones prepared by N -heterocyclic-carbene-catalyzed aroylation

(2018) Ryo Takashima et al.   TETRAHEDRON

Iridium/f-Amphol-catalyzed Efficient Asymmetric Hydrogenation of Benzo-fused Cyclic Ketones

(2018) Congcong Yin et al.   ADVANCED SYNTHESIS & CATALYSIS

Iridium-Catalyzed Asymmetric Hydrogenation of Halogenated Ketones for the Efficient Construction of Chiral Halohydrins

(2018) Congcong Yin et al.   ADVANCED SYNTHESIS & CATALYSIS

Large-scale preparation of key building blocks for the manufacture of fully synthetic macrolide antibiotics

(2017) Philip C Hogan et al.   JOURNAL OF ANTIBIOTICS

Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary Diseases

(2017) Martin Hemmerling et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pyridine-Directed Asymmetric Hydrogenation of 1,1-Diarylalkenes

(2017) Hailong Yang et al.   ORGANIC LETTERS

Enantioselective and Diastereoselective Construction of Chiral Amino Alcohols by Iridium–f-Amphox-Catalyzed Asymmetric Hydrogenation via Dynamic Kinetic Resolution

(2017) Weilong Wu et al.   ORGANIC LETTERS

Iridium-Catalyzed Asymmetric Hydrogenation of Ketones with Accessible and Modular Ferrocene-Based Amino-phosphine Acid (f-Ampha) Ligands

(2017) Jianfei Yu et al.   ORGANIC LETTERS

Enantioselective Iridium-Catalyzed Hydrogenation of α-Keto Amides to α-Hydroxy Amides

(2017) Guoxian Gu et al.   ORGANIC LETTERS

Asymmetric hydrogenation of α-hydroxy ketones with an iridium/f-amphox catalyst: efficient access to chiral 1,2-diols

(2017) Weilong Wu et al.   Organic Chemistry Frontiers

Efficient access to chiral 1,2-amino alcohols via Ir/f-amphox-catalyzed asymmetric hydrogenation of α-amino ketones

(2017) Yang Hu et al.   Organic Chemistry Frontiers

Readily Accessible and Highly Efficient Ferrocene-Based Amino-Phosphine-Alcohol (f-Amphol) Ligands for Iridium-Catalyzed Asymmetric Hydrogenation of Simple Ketones

(2016) Jianfei Yu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Iridium Catalysts with f-Amphox Ligands: Asymmetric Hydrogenation of Simple Ketones

(2016) Weilong Wu et al.   ORGANIC LETTERS

Rhodium-Catalyzed Asymmetric Hydrogenation of α,β-Unsaturated Carbonyl Compounds via Thiourea Hydrogen Bonding

(2016) Jialin Wen et al.   ORGANIC LETTERS

Recent Developments in Asymmetric Hydrogenation and Transfer Hydrogenation of Ketones and Imines through Dynamic Kinetic Resolution

(2016) Phannarath Phansavath et al.   SYNTHESIS-STUTTGART

Rhodium-catalyzed Asymmetric Hydrogenation of α-Dehydroamino Ketones: A General Approach to Chiral α-amino Ketones

(2015) Wenchao Gao et al.   Chemistry-An Asian Journal

Iridium-Catalyzed Asymmetric Hydrogenation of 2-Pyridyl Cyclic Imines: A Highly Enantioselective Approach to Nicotine Derivatives

(2015) Cui Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Chiral α-Amino Tertiary Boronic Esters by Enantioselective Hydroboration of α-Arylenamides

(2015) Naifu Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Isolation and structural determination of non-racemic tertiary cathinone derivatives

(2015) M.-J. Zhou et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly Enantioselective Hydrogenation of ο-Alkoxy Tetrasubstituted Enamides Catalyzed by a Rh/(R,S)-JosiPhos Catalyst

(2015) Jingjing Meng et al.   ORGANIC LETTERS

Asymmetric Synthesis of α-Amino Ketones by Brønsted Acid Catalysis

(2015) Wei Wen et al.   ORGANIC LETTERS

Evolution of a Manufacturing Route to Omarigliptin, A Long-Acting DPP-4 Inhibitor for the Treatment of Type 2 Diabetes

(2015) John Y. L. Chung et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

SpinPhox/Iridium(I)-Catalyzed Asymmetric Hydrogenation of Cyclic α-Alkylidene Carbonyl Compounds

(2014) Xu Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Asymmetric Hydrogenation of Unprotected NH Imines Assisted by a Thiourea

(2014) Qingyang Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Hydrogenation via Capture of Active Intermediates Generated from Aza-Pinacol Rearrangement

(2014) Chang-Bin Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Comparative Reactivity of Different Types of Stable Cyclic and Acyclic Mono- and Diamino Carbenes with Simple Organic Substrates

(2014) David Martin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Enantioselective Hydrogenation of Tetrasubstituted α-Acetoxy β-Enamido Esters: A New Approach to Chiral α-Hydroxyl-β-amino Acid Derivatives

(2014) Qingli Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Vicinal Aminoalcohols by Stereoselective Aza-Wacker Cyclizations: Access to (−)-Acosamine by Redox Relay

(2013) Adam B. Weinstein et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of new 1-phenyl-2-(4-substituted-piperazin-1-yl)-propanol derivatives and evaluation of their antidepressant-like effects

(2013) Ümide Demir Özkay et al.   ARCHIVES OF PHARMACAL RESEARCH

A Simple, Scalable Synthetic Route to (+)- and (−)-Pseudoephenamine

(2013) Kevin T. Mellem et al.   ORGANIC LETTERS

Pseudoephenamine: A Practical Chiral Auxiliary for Asymmetric Synthesis

(2012) Marvin R. Morales et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New Synthetic Strategy for High-Enantiopurity N-Protected α-Amino Ketones and their Derivatives by Asymmetric Hydrogenation

(2011) Tian Sun et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of unsymmetrical benzils using N-heterocyclic carbene catalysis

(2011) Yumiko Suzuki et al.   TETRAHEDRON

Recent Developments in Methodology for the Direct Oxyamination of Olefins

(2010) Timothy J. Donohoe et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantiopuretrans-3-Arylaziridine-2-carboxamides: Preparation by Bacterial Hydrolysis and Ring-Openings toward Enantiopure, Unnaturald-α-Amino Acids†

(2010) Roberto Morán-Ramallal et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Efficient Asymmetric Synthesis of Vinylic Amino Alcohols by Zn-Promoted Benzoyloxyallylation of ChiralN-tert-Butanesulfinyl Imines: Facile and Rapid Access to (−)-Cytoxazone

(2009) Min Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Enantioselective and Diastereoselective Synthesis of Chiral Amino Alcohols by Ruthenium-Catalyzed Asymmetric Hydrogenation of α-Amino Aliphatic Ketones

(2009) Jian-Hua Xie et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Antitumor potential of natural products from Mediterranean ascidians

(2009) Marialuisa Menna   PHYTOCHEMISTRY REVIEWS

Asymmetric Ring Opening ofmeso-Epoxides with Aromatic Amines Catalyzed by a New Proline-BasedN,N′-Dioxide-Indium Tris(triflate) Complex

(2008) Bo Gao et al.   ADVANCED SYNTHESIS & CATALYSIS