Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19

The pulmonary pathology of COVID-19

(2021) Hans Bösmüller et al.   VIRCHOWS ARCHIV

Emerging SARS-CoV-2 Variants and Impact in Global Vaccination Programs against SARS-CoV-2/COVID-19

(2021) Carmen Elena Gómez et al.   Vaccines

Risk factors for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections: a nationwide population-based study

(2021) Seon Cheol Park et al.   Annals of Translational Medicine

Current COVID-19 treatments: Rapid review of the literature

(2021) Yijia Dong et al.   Journal of Global Health

Role of Inflammatory Cytokines in COVID-19 Patients: A Review on Molecular Mechanisms, Immune Functions, Immunopathology and Immunomodulatory Drugs to Counter Cytokine Storm

(2021) Ali A. Rabaan et al.   Vaccines

Network-Based Analysis of Fatal Comorbidities of COVID-19 and Potential Therapeutics

(2021) Broto Chakrabarty et al.   IEEE-ACM Transactions on Computational Biology and Bioinformatics

Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19

(2021) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Distinct Airway Epithelial Stem Cells Hide among Club Cells but Mobilize to Promote Alveolar Regeneration

(2020) Jaymin J. Kathiriya et al.   Cell Stem Cell

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study

(2020) Heshui Shi et al.   LANCET INFECTIOUS DISEASES

Clinical, molecular and epidemiological characterization of the SARS-CoV2 virus and the Coronavirus disease 2019 (COVID-19), a comprehensive literature review

(2020) Esteban Ortiz-Prado et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

CT in coronavirus disease 2019 (COVID-19): a systematic review of chest CT findings in 4410 adult patients

(2020) Vineeta Ojha et al.   EUROPEAN RADIOLOGY

Abnormal pulmonary function in COVID-19 patients at time of hospital discharge

(2020) Xiaoneng Mo et al.   EUROPEAN RESPIRATORY JOURNAL

Effect of renin–angiotensin system on senescence

(2020) Masaki Mogi   Geriatrics & Gerontology International

SARS‐CoV‐2 viral spike G614 mutation exhibits higher case fatality rate

(2020) Manuel Becerra‐Flores et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Interferon-Induced Transmembrane Protein 3 Genetic Variant rs12252-C Associated With Disease Severity in Coronavirus Disease 2019

(2020) Yonghong Zhang et al.   JOURNAL OF INFECTIOUS DISEASES

Clinical Outcomes in COVID‐19 Patients Treated with Tocilizumab: An Individual Patient Data Systematic Review

(2020) Daniel Antwi‐Amoabeng et al.   JOURNAL OF MEDICAL VIROLOGY

APOE e4 genotype predicts severe COVID-19 in the UK Biobank community cohort

(2020) Chia-Ling Kuo et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

Clinical characteristics, outcomes, and risk factors for mortality in patients with cancer and COVID-19 in Hubei, China: a multicentre, retrospective, cohort study

(2020) Kunyu Yang et al.   LANCET ONCOLOGY

Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study

(2020) Annemarie B Docherty et al.   BMJ-British Medical Journal

Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy

(2020) Peter M George et al.   Lancet Respiratory Medicine

Coagulation Abnormalities and Thrombosis in Patients Infected With SARS-CoV-2 and Other Pandemic Viruses

(2020) Nigel Mackman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

COVID-19 and coagulation: bleeding and thrombotic manifestations of SARS-CoV-2 infection

(2020) Hanny Al-Samkari et al.   BLOOD

Thrombosis in Coronavirus disease 2019 (COVID-19) through the prism of Virchow’s triad

(2020) Sakir Ahmed et al.   CLINICAL RHEUMATOLOGY

Insights into pathogenesis of fatal COVID‐19 pneumonia from histopathology with immunohistochemical and viral RNA studies

(2020) Jennifer L. Sauter et al.   HISTOPATHOLOGY

Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19)

(2020) W. Joost Wiersinga et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Lung fibrosis: an undervalued finding in COVID-19 pathological series

(2020) Federica Grillo et al.   LANCET INFECTIOUS DISEASES

A systematic review of pathological findings in COVID-19: a pathophysiological timeline and possible mechanisms of disease progression

(2020) Samuel B. Polak et al.   MODERN PATHOLOGY

Correlation analysis of the severity and clinical prognosis of 32 cases of patients with COVID-19

(2020) Ming Ding et al.   RESPIRATORY MEDICINE

Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody

(2020) Zhe Lv et al.   SCIENCE

Structural basis of a shared antibody response to SARS-CoV-2

(2020) Meng Yuan et al.   SCIENCE

COVID-19-associated coagulopathy: An exploration of mechanisms

(2020) Meaghan E Colling et al.   VASCULAR MEDICINE

Lung Surfactant for Pulmonary Barrier Restoration in Patients With COVID-19 Pneumonia

(2020) Ursula Mirastschijski et al.   Frontiers in Medicine

Cellular senescence as a potential mediator of COVID‐19 severity in the elderly

(2020) Jamil Nehme et al.   AGING CELL

Immunopathology of Hyperinflammation in COVID-19

(2020) Joshua N. Gustine et al.   AMERICAN JOURNAL OF PATHOLOGY

Coagulopathy and thromboembolic events in patients with SARS-CoV-2 infection: pathogenesis and management strategies

(2020) Alessandro Allegra et al.   ANNALS OF HEMATOLOGY

Beyond dexamethasone, emerging immuno‐thrombotic therapies for COVID‐19

(2020) Melanie Peta Jensen et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Stem cell therapy for COVID‐19, ARDS and pulmonary fibrosis

(2020) Zhongwen Li et al.   CELL PROLIFERATION

Complement and tissue factor–enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis

(2020) Panagiotis Skendros et al.   JOURNAL OF CLINICAL INVESTIGATION

COVID-19 pulmonary pathology: a multi-institutional autopsy cohort from Italy and New York City

(2020) Alain C. Borczuk et al.   MODERN PATHOLOGY

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

(2020) Qian Zhang et al.   SCIENCE

Two distinct immunopathological profiles in autopsy lungs of COVID-19

(2020) Ronny Nienhold et al.   Nature Communications

Severity and mortality of COVID 19 in patients with diabetes, hypertension and cardiovascular disease: a meta-analysis

(2020) Bianca de Almeida-Pititto et al.   Diabetology & Metabolic Syndrome

Perspective on fibrinolytic therapy in COVID-19: the potential of inhalation therapy against suppressed-fibrinolytic-type DIC

(2020) Hidesaku Asakura et al.   Journal of Intensive Care

Mesenchymal stem cell immunomodulation and regeneration therapeutics as an ameliorative approach for COVID-19 pandemics

(2020) Pooja Yadav et al.   LIFE SCIENCES

COVID-19 and Neutrophils: The Relationship between Hyperinflammation and Neutrophil Extracellular Traps

(2020) Leandro Borges et al.   MEDIATORS OF INFLAMMATION

Genetic mechanisms of critical illness in Covid-19

(2020) Erola Pairo-Castineira et al.   NATURE

Pulmonary pathology of ARDS in COVID-19: A pathological review for clinicians

(2020) Sabrina Setembre Batah et al.   RESPIRATORY MEDICINE

Anticoagulation and bleeding risk in patients with COVID-19

(2020) Nancy Musoke et al.   THROMBOSIS RESEARCH

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study

(2019) Jamie N. Justice et al.   EBioMedicine

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

(2019) Daehwan Kim et al.   NATURE BIOTECHNOLOGY

Targeting senescent cells in translational medicine

(2019) Marta Paez‐Ribes et al.   EMBO Molecular Medicine

Production of amphiregulin and recovery from influenza is greater in males than females

(2018) Meghan S. Vermillion et al.   Biology of Sex Differences

Endothelial cell senescence in aging-related vascular dysfunction

(2018) Guanghong Jia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosisex vivo

(2017) Mareike Lehmann et al.   EUROPEAN RESPIRATORY JOURNAL

Endothelial cell senescence and thrombosis: Ageing clots

(2016) Magdalena L. Bochenek et al.   THROMBOSIS RESEARCH

S100A12 is up-regulated in pulmonary tuberculosis and predicts the extent of alveolar infiltration on chest radiography: an observational study

(2016) Luis C. Berrocal-Almanza et al.   Scientific Reports

Fibroblast Growth Factor 2 Is Required for Epithelial Recovery, but Not for Pulmonary Fibrosis, in Response to Bleomycin

(2015) Robert D. Guzy et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Breakdown of Epithelial Barrier Integrity and Overdrive Activation of Alveolar Epithelial Cells in the Pathogenesis of Acute Respiratory Distress Syndrome and Lung Fibrosis

(2015) Shigehisa Yanagi et al.   Biomed Research International

Breaking Barriers. New Insights into Airway Epithelial Barrier Function in Health and Disease

(2014) Fariba Rezaee et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Lung Stem Cell Differentiation in Mice Directed by Endothelial Cells via a BMP4-NFATc1-Thrombospondin-1 Axis

(2014) Joo-Hyeon Lee et al.   CELL

Repair and Regeneration of the Respiratory System: Complexity, Plasticity, and Mechanisms of Lung Stem Cell Function

(2014) Brigid L.M. Hogan et al.   Cell Stem Cell

C5a and TNF-  Up-Regulate the Expression of Tissue Factor in Intra-Alveolar Neutrophils of Patients with the Acute Respiratory Distress Syndrome

(2014) K. Kambas et al.   JOURNAL OF IMMUNOLOGY

Treatment with the reactive oxygen species scavenger EUK-207 reduces lung damage and increases survival during 1918 influenza virus infection in mice

(2013) John C. Kash et al.   FREE RADICAL BIOLOGY AND MEDICINE

Stem cell factor improves lung recovery in rats following neonatal hyperoxia-induced lung injury

(2013) Luis F. Miranda et al.   PEDIATRIC RESEARCH

VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

(2012) D. C. Koboldt et al.   GENOME RESEARCH

Lethal Synergism of 2009 Pandemic H1N1 Influenza Virus and Streptococcus pneumoniae Coinfection Is Associated with Loss of Murine Lung Repair Responses

(2011) J. C. Kash et al.   mBio

Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling

(2010) J. R. Rock et al.   Disease Models & Mechanisms

VarScan: variant detection in massively parallel sequencing of individual and pooled samples

(2009) Daniel C. Koboldt et al.   BIOINFORMATICS

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Basal cells as stem cells of the mouse trachea and human airway epithelium

(2009) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How corticosteroids control inflammation: Quintiles Prize Lecture 2005

(2006) Peter J Barnes   BRITISH JOURNAL OF PHARMACOLOGY