COVID-19 and Neutrophils: The Relationship between Hyperinflammation and Neutrophil Extracellular Traps

Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China

(2020) Qiurong Ruan et al.   INTENSIVE CARE MEDICINE

Neutrophil Adaptations upon Recruitment to the Lung: New Concepts and Implications for Homeostasis and Disease

(2020) Vincent D. Giacalone et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

(2020) Dawei Wang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

(2020) Nanshan Chen et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Clinical Characteristics of Coronavirus Disease 2019 in China

(2020) Wei-jie Guan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China

(2020) Chuan Qin et al.   CLINICAL INFECTIOUS DISEASES

SARS-CoV-2 Inflammatory Syndrome. Clinical Features and Rationale for Immunological Treatment

(2020) Marcella Prete et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeting potential drivers of COVID-19: Neutrophil extracellular traps

(2020) Betsy J. Barnes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophils at the crossroads of innate and adaptive immunity

(2020) Carlos Rosales   JOURNAL OF LEUKOCYTE BIOLOGY

Neutrophil-to-lymphocyte ratio and lymphocyte-to-C-reactive protein ratio in patients with severe coronavirus disease 2019 (COVID-19): A meta-analysis

(2020) Francisco Alejandro Lagunas-Rangel   JOURNAL OF MEDICAL VIROLOGY

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation

(2020) Jun Jacob Hu et al.   NATURE IMMUNOLOGY

Association of Coronavirus Disease 2019 (COVID-19) With Myocardial Injury and Mortality

(2020) Robert O. Bonow et al.   JAMA Cardiology

Neutrophil Extracellular Traps (NETs) Contribute to Immunothrombosis in COVID-19 Acute Respiratory Distress Syndrome

(2020) Elizabeth A Middleton et al.   BLOOD

Immunothrombotic Dysregulation in COVID-19 Pneumonia is Associated with Respiratory Failure and Coagulopathy

(2020) Leo Nicolai et al.   CIRCULATION

Abnormalities of peripheral blood system in patients with COVID-19 in Wenzhou, China

(2020) Suyu Sun et al.   CLINICA CHIMICA ACTA

Neutrophil Extracellular Traps (NETs) and Damage-Associated Molecular Patterns (DAMPs): Two Potential Targets for COVID-19 Treatment

(2020) Sebastiano Cicco et al.   MEDIATORS OF INFLAMMATION

Complement and tissue factor–enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis

(2020) Panagiotis Skendros et al.   JOURNAL OF CLINICAL INVESTIGATION

Saliva in the Diagnosis of COVID-19: A Review and New Research Directions

(2020) L.L. Fernandes et al.   JOURNAL OF DENTAL RESEARCH

SARS-CoV-2–triggered neutrophil extracellular traps mediate COVID-19 pathology

(2020) Flavio Protasio Veras et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Therapeutic Options Against the New Coronavirus: Updated Clinical and Laboratory Evidences

(2020) Amélia Carolina Lopes Fernandes et al.   Frontiers in Medicine

Untangling “NETosis” from NETs

(2019) Shida Yousefi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Neutrophil Extracellular Traps Are Elevated in Patients with Pneumonia-related Acute Respiratory Distress Syndrome

(2019) Inès Bendib et al.   ANESTHESIOLOGY

The Role of Innate Leukocytes during Influenza Virus Infection

(2019) Prem P. Lamichhane et al.   Journal of Immunology Research

Insights into the immuno-pathogenesis of acute respiratory distress syndrome

(2019) Judith Ju Ming Wong et al.   Annals of Translational Medicine

MERS-CoV infection in humans is associated with a pro-inflammatory Th1 and Th17 cytokine profile

(2018) Waleed H. Mahallawi et al.   CYTOKINE

Targeting pattern-recognition receptors to discover new small molecule immune modulators

(2018) Gengzheng Zhu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

High Level of Neutrophil Extracellular Traps Correlates With Poor Prognosis of Severe Influenza A Infection

(2018) Liuluan Zhu et al.   JOURNAL OF INFECTIOUS DISEASES

Neutrophil extracellular traps prevent HIV infection in the female genital tract

(2018) Fiona D. Barr et al.   Mucosal Immunology

Neutrophil Elastase Subverts the Immune Response by Cleaving Toll-Like Receptors and Cytokines in Pneumococcal Pneumonia

(2018) Hisanori Domon et al.   Frontiers in Immunology

Recent advances on the crosstalk between neutrophils and B or T lymphocytes

(2018) Sara Costa et al.   IMMUNOLOGY

Respiratory Syncytial Virus induces the classical ROS-dependent NETosis through PAD-4 and necroptosis pathways activation

(2018) Stéfanie P. Muraro et al.   Scientific Reports

Physiological Stimuli Induce PAD4-Dependent, ROS-Independent NETosis, With Early and Late Events Controlled by Discrete Signaling Pathways

(2018) Olga Tatsiy et al.   Frontiers in Immunology

An emerging role for neutrophil extracellular traps in noninfectious disease

(2017) Selina K Jorch et al.   NATURE MEDICINE

Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

(2017) Rudragouda Channappanavar et al.   Seminars in Immunopathology

Neutrophil Extracellular Traps and Its Implications in Inflammation: An Overview

(2017) Vidal Delgado-Rizo et al.   Frontiers in Immunology

Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation

(2016) Christian C. Yost et al.   JOURNAL OF CLINICAL INVESTIGATION

Comparative and kinetic analysis of viral shedding and immunological responses in MERS patients representing a broad spectrum of disease severity

(2016) Chan-Ki Min et al.   Scientific Reports

Respiratory Syncytial Virus Fusion Protein Promotes TLR-4–Dependent Neutrophil Extracellular Trap Formation by Human Neutrophils

(2015) Giselle A. Funchal et al.   PLoS One

Neutrophils Recruited to Sites of Infection Protect from Virus Challenge by Releasing Neutrophil Extracellular Traps

(2013) Craig N. Jenne et al.   Cell Host & Microbe

NET balancing: a problem in inflammatory lung diseases

(2013) Olivia Z. Cheng et al.   Frontiers in Immunology

Neutrophil Extracellular Traps Mediate a Host Defense Response to Human Immunodeficiency Virus-1

(2012) Tatsuya Saitoh et al.   Cell Host & Microbe

Understanding the roles of cytokines and neutrophil activity and neutrophil apoptosis in the protective versus deleterious inflammatory response in pneumonia

(2012) Jose Bordon et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Influenza-Infected Neutrophils within the Infected Lungs Act as Antigen Presenting Cells for Anti-Viral CD8+ T Cells

(2012) Matthew M. Hufford et al.   PLoS One

Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis

(2011) Teluguakula Narasaraju et al.   AMERICAN JOURNAL OF PATHOLOGY

A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1

(2011) Janesh Pillay et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

A Systemic Neutrophil Response Precedes Robust CD8+ T-Cell Activation during Natural Respiratory Syncytial Virus Infection in Infants

(2009) M. V. Lukens et al.   JOURNAL OF VIROLOGY

H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of Mice

(2008) Lucy A. Perrone et al.   PLoS Pathogens