Complement and tissue factor–enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

(2020) Dawei Wang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Traps N' Clots: NET-Mediated Thrombosis and Related Diseases

(2020) Dimitrios Stakos et al.   THROMBOSIS AND HAEMOSTASIS

COVID-19 and its implications for thrombosis and anticoagulation

(2020) Jean Marie Connors et al.   BLOOD

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

Complement activation in patients with COVID-19: A novel therapeutic target

(2020) Massimo Cugno et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Targeting potential drivers of COVID-19: Neutrophil extracellular traps

(2020) Betsy J. Barnes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Endothelial cell infection and endotheliitis in COVID-19

(2020) Zsuzsanna Varga et al.   LANCET

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19

(2020) Maximilian Ackermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases

(2020) Cynthia Magro et al.   Translational Research

Pulmonary and cardiac pathology in African American patients with COVID-19: an autopsy series from New Orleans

(2020) Sharon E Fox et al.   Lancet Respiratory Medicine

Hematological findings in coronavirus disease 2019: indications of progression of disease

(2020) Xiaoqing Liu et al.   ANNALS OF HEMATOLOGY

The complement system in COVID-19: friend and foe?

(2020) Anuja Java et al.   JCI Insight

A Functional Relevance of the Anaphylatoxin Receptor C3aR for Platelet Function and Arterial Thrombus Formation Marks an Intersection Point Between Innate Immunity and Thrombosis

(2018) Reinhard J. Sauter et al.   CIRCULATION

Complement inhibition by hydroxychloroquine prevents placental and fetal brain abnormalities in antiphospholipid syndrome

(2016) Maria Laura Bertolaccini et al.   JOURNAL OF AUTOIMMUNITY

Coagulation induced by C3aR-dependent NETosis drives protumorigenic neutrophils during small intestinal tumorigenesis

(2016) Silvia Guglietta et al.   Nature Communications

Expression of functional tissue factor by neutrophil extracellular traps in culprit artery of acute myocardial infarction

(2015) Dimitrios A. Stakos et al.   EUROPEAN HEART JOURNAL

Promotion of Hypercoagulability in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis by C5a-Induced Tissue Factor-Expressing Microparticles and Neutrophil Extracellular Traps

(2015) Yi-Min Huang et al.   Arthritis & Rheumatology

The protective effect of antimalarial drugs on thrombovascular events in systemic lupus erythematosus

(2010) Hyejung Jung et al.   ARTHRITIS AND RHEUMATISM

Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosis

(2010) I. Kourtzelis et al.   BLOOD