Breakdown of Epithelial Barrier Integrity and Overdrive Activation of Alveolar Epithelial Cells in the Pathogenesis of Acute Respiratory Distress Syndrome and Lung Fibrosis

Reemergence of Hedgehog Mediates Epithelial–Mesenchymal Crosstalk in Pulmonary Fibrosis

(2015) Biao Hu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Revealing the Pathogenic and Aging-related Mechanisms of the Enigmatic Idiopathic Pulmonary Fibrosis. An Integral Model

(2014) Moisés Selman et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Repair and Regeneration of the Respiratory System: Complexity, Plasticity, and Mechanisms of Lung Stem Cell Function

(2014) Brigid L.M. Hogan et al.   Cell Stem Cell

PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis

(2014) Marta Bueno et al.   JOURNAL OF CLINICAL INVESTIGATION

Alveolar progenitor and stem cells in lung development, renewal and cancer

(2014) Tushar J. Desai et al.   NATURE

Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury

(2014) Andrew E. Vaughan et al.   NATURE

A large kindred of pulmonary fibrosis associated with a novel ABCA3 gene variant

(2014) Ilaria Campo et al.   RESPIRATORY RESEARCH

Novel concepts of acute lung injury and alveolar-capillary barrier dysfunction

(2013) Susanne Herold et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Mechanistic links between aging and lung fibrosis

(2013) Victor J. Thannickal   BIOGERONTOLOGY

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Alveolar epithelial cells: Master regulators of lung homeostasis

(2013) Loïc Guillot et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Matrix Metalloproteinase (MMP)-1 Induces Lung Alveolar Epithelial Cell Migration and Proliferation, Protects from Apoptosis, and Represses Mitochondrial Oxygen Consumption

(2013) Iliana Herrera et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type 2 alveolar cells are stem cells in adult lung

(2013) Christina E. Barkauskas et al.   JOURNAL OF CLINICAL INVESTIGATION

Epidemiology of idiopathic pulmonary fibrosis

(2013) Brett Ley et al.   Clinical Epidemiology

CXCR4 regulates migration of lung alveolar epithelial cells through activation of Rac1 and matrix metalloproteinase-2

(2012) Manik C. Ghosh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Role of Sonic Hedgehog in idiopathic pulmonary fibrosis

(2012) Alfredo Lozano Bolaños et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Insufficient autophagy in idiopathic pulmonary fibrosis

(2012) Jun Araya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Alveolar Epithelial Cell Disintegrity and Subsequent Activation

(2012) Moisés Selman et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Tetraspanin CD151 Protects against Pulmonary Fibrosis by Maintaining Epithelial Integrity

(2012) Kazuyuki Tsujino et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Epithelial Pten Controls Acute Lung Injury and Fibrosis by Regulating Alveolar Epithelial Cell Integrity

(2012) Kahori Miyoshi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Roles for claudins in alveolar epithelial barrier function

(2012) Christian E. Overgaard et al.   Annals of the New York Academy of Sciences

Loss of Shp2 in alveoli epithelia induces deregulated surfactant homeostasis, resulting in spontaneous pulmonary fibrosis

(2012) Xue Zhang et al.   FASEB JOURNAL

The acute respiratory distress syndrome

(2012) Michael A. Matthay et al.   JOURNAL OF CLINICAL INVESTIGATION

Type I Alveolar Epithelial Cells Mount Innate Immune Responses during Pneumococcal Pneumonia

(2012) K. Yamamoto et al.   JOURNAL OF IMMUNOLOGY

Functional characterization of pulmonary neuroendocrine cells in lung development, injury, and tumorigenesis

(2012) H. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Claudin-4 Levels Are Associated with Intact Alveolar Fluid Clearance in Human Lungs

(2011) Deepti Rokkam et al.   AMERICAN JOURNAL OF PATHOLOGY

Differential effects of claudin-3 and claudin-4 on alveolar epithelial barrier function

(2011) Leslie A. Mitchell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment

(2011) Amber L. Degryse et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Acute Respiratory Distress Syndrome: Pathogenesis and Treatment

(2011) Michael A. Matthay et al.   Annual Review of Pathology-Mechanisms of Disease

Epithelial-Mesenchymal Interactions in Pulmonary Fibrosis

(2011) Harold A. Chapman   Annual Review of Physiology

Distal Airway Stem Cells Yield Alveoli In Vitro and during Lung Regeneration following H1N1 Influenza Infection

(2011) Pooja A. Kumar et al.   CELL

Integrin α6β4 identifies an adult distal lung epithelial population with regenerative potential in mice

(2011) Harold A. Chapman et al.   JOURNAL OF CLINICAL INVESTIGATION

Ligand-independent transforming growth factor-β type I receptor signalling mediates type I collagen-induced epithelial-mesenchymal transition

(2011) Lucas DeMaio et al.   JOURNAL OF PATHOLOGY

Idiopathic pulmonary fibrosis

(2011) Talmadge E King et al.   LANCET

Neutrophil transmigration triggers repair of the lung epithelium via  -catenin signaling

(2011) R. L. Zemans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

(2011) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Keratinocyte growth factor enhances barrier function without altering claudin expression in primary alveolar epithelial cells

(2010) Michael J. LaFemina et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Epithelial repair mechanisms in the lung

(2010) Lynn M. Crosby et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis

(2010) Min Li et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

(2010) Gang Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin motifs in non-neoplastic diseases

(2010) Takayuki Shiomi et al.   PATHOLOGY INTERNATIONAL

Inhibition of Wnt/ -catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis

(2010) W. R. Henderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Claudin-4 augments alveolar epithelial barrier function and is induced in acute lung injury

(2009) Charlie Wray et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Deletion ofPtenExpands Lung Epithelial Progenitor Pools and Confers Resistance to Airway Injury

(2009) Caterina Tiozzo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Contribution of Epithelial-derived Fibroblasts to Bleomycin-induced Lung Fibrosis

(2009) Harikrishna Tanjore et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

WNT5A Is a Regulator of Fibroblast Proliferation and Resistance to Apoptosis

(2009) Louis J. Vuga et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

WNT Signaling in Lung Disease

(2009) Melanie Königshoff et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

The Role of Scgb1a1+ Clara Cells in the Long-Term Maintenance and Repair of Lung Airway, but Not Alveolar, Epithelium

(2009) Emma L. Rawlins et al.   Cell Stem Cell

New Mechanisms of Pulmonary Fibrosis

(2009) Robert M. Strieter et al.   CHEST

WNT1-inducible signaling protein–1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis

(2009) Melanie Königshoff et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury

(2009) Chris J. Scotton et al.   JOURNAL OF CLINICAL INVESTIGATION

Animal models of acute lung injury

(2008) Gustavo Matute-Bello et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Contribution of Epithelial Sodium Channels to Alveolar Function in Health and Disease

(2008) Douglas C. Eaton et al.   Annual Review of Physiology

Usual Interstitial Pneumonia in an Adolescent With ABCA3 Mutations*

(2008) Lisa R. Young et al.   CHEST

Advances in mechanisms of repair and remodelling in acute lung injury

(2008) Claudia C. Dos Santos   INTENSIVE CARE MEDICINE

Fibrocytes are a potential source of lung fibroblasts in idiopathic pulmonary fibrosis

(2008) Annika Andersson-Sjöland et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Epithelial cell α3β1 integrin links β-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis

(2008) Kevin K. Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis

(2008) Hong Xia et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE

The role of PTEN signaling perturbations in cancer and in targeted therapy

(2008) M Keniry et al.   ONCOGENE

Functional Wnt Signaling Is Increased in Idiopathic Pulmonary Fibrosis

(2008) Melanie Königshoff et al.   PLoS One

Short telomeres are a risk factor for idiopathic pulmonary fibrosis

(2008) J. K. Alder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA