Dietary nutrition for neurological disease therapy: Current status and future directions

Ketogenic Diets

(2020) Zhaoping Li et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Immune cell regulation of glia during CNS injury and disease

(2020) Andrew D. Greenhalgh et al.   NATURE REVIEWS NEUROSCIENCE

Protective Effects of Chlorogenic Acid on Cerebral Ischemia/Reperfusion Injury Rats by Regulating Oxidative Stress-Related Nrf2 Pathway

(2020) Dequan Liu et al.   Drug Design Development and Therapy

Human Milk Oligosaccharide 2′-Fucosyllactose Reduces Neurodegeneration in Stroke Brain

(2020) Kou-Jen Wu et al.   Translational Stroke Research

Selenium restores synaptic deficits by modulating NMDA receptors and selenoprotein K in an Alzheimer’s disease model

(2020) Zhonghao Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

Relationship between cortical iron and tau aggregation in Alzheimer’s disease

(2020) Nicola Spotorno et al.   BRAIN

Genetic Screen for Cell Fitness in High or Low Oxygen Highlights Mitochondrial and Lipid Metabolism

(2020) Isha H. Jain et al.   CELL

A novel pectin from Polygala tenuifolia blocks Aβ42 aggregation and production by enhancing insulin-degradation enzyme and neprilysin

(2020) Hui Zeng et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

(2020) Erik C. B. Johnson et al.   NATURE MEDICINE

Dysfunction of ABC transporters at the blood-brain barrier: Role in neurological disorders

(2020) Eva Gil-Martins et al.   PHARMACOLOGY & THERAPEUTICS

Active form of vitamin D analogue mitigates neurodegenerative changes in Alzheimer’s disease in rats by targeting Keap1/Nrf2 and MAPK-38p/ERK signaling pathways

(2020) Shimaa Saad El-Din et al.   STEROIDS

Schisandra Extract and Ascorbic Acid Synergistically Enhance Cognition in Mice through Modulation of Mitochondrial Respiration

(2020) Yunseon Jang et al.   Nutrients

Quercetin Attenuates Atherosclerosis via Modulating Oxidized LDL-Induced Endothelial Cellular Senescence

(2020) Yue-Hua Jiang et al.   Frontiers in Pharmacology

ATP Synthase c-Subunit Leak Causes Aberrant Cellular Metabolism in Fragile X Syndrome

(2020) Pawel Licznerski et al.   CELL

Increase in Seizure Susceptibility After Repetitive Concussion Results from Oxidative Stress, Parvalbumin-Positive Interneuron Dysfunction and Biphasic Increases in Glutamate/GABA Ratio

(2020) Paul MacMullin et al.   CEREBRAL CORTEX

Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites

(2020) Xiang Zhang et al.   GUT

Mechanism of Manganese Dysregulation of Dopamine Neuronal Activity

(2020) Min Lin et al.   JOURNAL OF NEUROSCIENCE

Dietary Amino Acids Impact LRRK2-Induced Neurodegeneration in Parkinson's Disease Models

(2020) Vinita G. Chittoor-Vinod et al.   JOURNAL OF NEUROSCIENCE

Dichotomous engagement of HDAC3 activity governs inflammatory responses

(2020) Hoang C. B. Nguyen et al.   NATURE

Microbiota modulate sympathetic neurons via a gut–brain circuit

(2020) Paul A. Muller et al.   NATURE

Na+ controls hypoxic signalling by the mitochondrial respiratory chain

(2020) Pablo Hernansanz-Agustín et al.   NATURE

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

(2020) Stephen C. Cunnane et al.   NATURE REVIEWS DRUG DISCOVERY

L-Serine links metabolism with neurotransmission

(2020) Marianne Maugard et al.   PROGRESS IN NEUROBIOLOGY

Curcumin alleviates neuroinflammation, enhances hippocampal neurogenesis, and improves spatial memory after traumatic brain injury

(2020) Guangchi Sun et al.   BRAIN RESEARCH BULLETIN

TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS

(2020) Chien-Hsiung Yu et al.   CELL

Hindbrain Double-Negative Feedback Mediates Palatability-Guided Food and Water Consumption

(2020) Rong Gong et al.   CELL

Diet Diurnally Regulates Small Intestinal Microbiome-Epithelial-Immune Homeostasis and Enteritis

(2020) Timur Tuganbaev et al.   CELL

Lactate Elicits ER-Mitochondrial Mg2+ Dynamics to Integrate Cellular Metabolism

(2020) Cassidy C. Daw et al.   CELL

Yeast β-glucan alleviates cognitive deficit by regulating gut microbiota and metabolites in Aβ1–42-induced AD-like mice

(2020) Mengdai Xu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Vitamin B12, B6, or Folate and Cognitive Function in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis

(2020) Chenbo Zhang et al.   JOURNAL OF ALZHEIMERS DISEASE

Quercetin alleviates kidney fibrosis by reducing renal tubular epithelial cell senescence through the SIRT1/PINK1/mitophagy axis

(2020) Tao Liu et al.   LIFE SCIENCES

The maternal microbiome modulates fetal neurodevelopment in mice

(2020) Helen E. Vuong et al.   NATURE

Vitamin D attenuated 6-OHDA-induced behavioural deficits, dopamine dysmetabolism, oxidative stress, and neuro-inflammation in mice

(2020) Adedamola Bayo-Olugbami et al.   NUTRITIONAL NEUROSCIENCE

The neuroprotective effect of curcumin against Cd-induced neurotoxicity and hippocampal neurogenesis promotion through CREB-BDNF signaling pathway

(2020) Dhondup Namgyal et al.   TOXICOLOGY

Hypervitaminosis A Following the Ingestion of Fish Liver: Report on 3 Cases from the Poison Control Center in Marseille

(2020) Corinne Schmitt et al.   WILDERNESS & ENVIRONMENTAL MEDICINE

Human breast milk as source of sphingolipids for newborns: comparison with infant formulas and commercial cow’s milk

(2020) Michele Dei Cas et al.   Journal of Translational Medicine

Isotope-reinforced polyunsaturated fatty acids improve Parkinson’s disease-like phenotype in rats overexpressing α-synuclein

(2020) M. Flint Beal et al.   Acta Neuropathologica Communications

Effects of caloric restriction on the antagonistic and integrative hallmarks of aging

(2020) Begun Erbaba et al.   AGEING RESEARCH REVIEWS

Iron accumulation in microglia triggers a cascade of events that leads to altered metabolism and compromised function in APP/PS1 mice

(2019) Allison McIntosh et al.   BRAIN PATHOLOGY

Improving effect of a probiotic mixture on memory and learning abilities in d-galactose–treated aging mice

(2019) Shang-Tse Ho et al.   JOURNAL OF DAIRY SCIENCE

Pro-cognitive effect of a prebiotic in psychosis: A double blind placebo controlled cross-over study

(2019) Amy Chia-Ching Kao et al.   SCHIZOPHRENIA RESEARCH

Neuroprotection of Fasting Mimicking Diet on MPTP-Induced Parkinson’s Disease Mice via Gut Microbiota and Metabolites

(2019) Zhi-Lan Zhou et al.   Neurotherapeutics

Prebiotic reduction of brain histone deacetylase (HDAC) activity and olanzapine-mediated weight gain in rats, are acetate independent

(2019) Amy Chia-Ching Kao et al.   NEUROPHARMACOLOGY

The proteostasis network and its decline in ageing

(2019) Mark S. Hipp et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protective properties of the aqueous extract of saffron (Crocus sativus L.) in ischemic stroke, randomized clinical trial

(2019) Mostafa Asadollahi et al.   JOURNAL OF ETHNOPHARMACOLOGY

The Role of Apolipoprotein E Isoforms in Alzheimer’s Disease

(2019) Alejandro R. Roda et al.   JOURNAL OF ALZHEIMERS DISEASE

A novel, highly-water-soluble apigenin derivative provides neuroprotection following ischemia in male rats by regulating the ERK/Nrf2/HO-1 pathway

(2019) Sen Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Treatment of Neurological Manifestations of Gluten Sensitivity and Coeliac Disease

(2019) Panagiotis Zis et al.   Current Treatment Options in Neurology

Vitamin B12 modulates Parkinson’s disease LRRK2 kinase activity through allosteric regulation and confers neuroprotection

(2019) Adam Schaffner et al.   CELL RESEARCH

MIND not Mediterranean diet related to 12-year incidence of cognitive impairment in an Australian longitudinal cohort study

(2019) Diane E. Hosking et al.   Alzheimers & Dementia

Nerve Growth Factor modulates LPS - induced microglial glycolysis and inflammatory responses

(2019) Georgia Fodelianaki et al.   EXPERIMENTAL CELL RESEARCH

Melatonin Alleviates Cognition Impairment by Antagonizing Brain Insulin Resistance in Aged Rats Fed a High‐Fat Diet

(2019) Jiqu Xu et al.   JOURNAL OF PINEAL RESEARCH

The role of short-chain fatty acids in microbiota–gut–brain communication

(2019) Boushra Dalile et al.   Nature Reviews Gastroenterology & Hepatology

Preventing adolescent stress-induced cognitive and microbiome changes by diet

(2019) Gustavo Provensi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microglia immunometabolism: From metabolic disorders to single cell metabolism

(2019) Rosa C. Paolicelli et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Astrocytes: Emerging Therapeutic Targets in Neurological Disorders

(2019) Chiara F. Valori et al.   TRENDS IN MOLECULAR MEDICINE

SIRT3 mediates hippocampal synaptic adaptations to intermittent fasting and ameliorates deficits in APP mutant mice

(2019) Yong Liu et al.   Nature Communications

Vitamin B12 Enhances Nerve Repair and Improves Functional Recovery After Traumatic Brain Injury by Inhibiting ER Stress-Induced Neuron Injury

(2019) Fangfang Wu et al.   Frontiers in Pharmacology

A Review of Cognitive Outcomes Across Movement Disorder Patients Undergoing Deep Brain Stimulation

(2019) Stephanie Cernera et al.   Frontiers in Neurology

Dietary fructose-induced gut dysbiosis promotes mouse hippocampal neuroinflammation: a benefit of short-chain fatty acids

(2019) Jian-Mei Li et al.   Microbiome

Targeting microRNA-134 for seizure control and disease modification in epilepsy

(2019) Gareth Morris et al.   EBioMedicine

Epigallocatechin‐3‐Gallate Attenuates Microglial Inflammation and Neurotoxicity by Suppressing the Activation of Canonical and Noncanonical Inflammasome via TLR4/NF‐κB Pathway

(2019) Xin Zhong et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Dietary restriction improves proteostasis and increases life span through endoplasmic reticulum hormesis

(2019) Latika Matai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Midlife Insulin Resistance as a Predictor for Late-Life Cognitive Function and Cerebrovascular Lesions

(2019) Sini Toppala et al.   JOURNAL OF ALZHEIMERS DISEASE

Effects of crocin in reducing DNA damage, inflammation, and oxidative stress in multiple sclerosis patients: A double‐blind, randomized, and placebo‐controlled trial

(2019) Masoud Ghiasian et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Effect of Chlorogenic Acids on Cognitive Function in Mild Cognitive Impairment: A Randomized Controlled Crossover Trial

(2019) Ryuji Ochiai et al.   JOURNAL OF ALZHEIMERS DISEASE

Efficacy of oral administration of licorice as an adjunct therapy on improving the symptoms of patients with Parkinson's disease, A randomized double blinded clinical trial

(2019) Peyman Petramfar et al.   JOURNAL OF ETHNOPHARMACOLOGY

The global burden of neurological disorders: translating evidence into policy

(2019) Valery L Feigin et al.   LANCET NEUROLOGY

Meta‐analysis of copper and iron in Parkinson's disease brain and biofluids

(2019) Sian Genoud et al.   MOVEMENT DISORDERS

The protocol for the Cannabidiol in children with refractory epileptic encephalopathy (CARE-E) study: a phase 1 dosage escalation study

(2018) Darren Reithmeier et al.   BMC Pediatrics

Inflammatory microglia are glycolytic and iron retentive and typify the microglia in APP/PS1 mice

(2018) R. Holland et al.   BRAIN BEHAVIOR AND IMMUNITY

The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet

(2018) Christine A. Olson et al.   CELL

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

(2018) Irina Ingold et al.   CELL

Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States

(2018) Mark P. Mattson et al.   Cell Metabolism

Isoquercetin attenuates oxidative stress and neuronal apoptosis after ischemia/reperfusion injury via Nrf2-mediated inhibition of the NOX4/ROS/NF-κB pathway

(2018) Yunyi Dai et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Increased cortical neuronal responses to NMDA and improved attentional set-shifting performance in rats following prebiotic (B-GOS ® ) ingestion

(2018) Benjamin Gronier et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Intermittent fasting protects against the deterioration of cognitive function, energy metabolism and dyslipidemia in Alzheimer’s disease-induced estrogen deficient rats

(2018) Bae Kun Shin et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Characterization of a pectin from Lonicera japonica Thunb. and its inhibition effect on Aβ 42 aggregation and promotion of neuritogenesis

(2018) Qin Liu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Dietary Zinc Modulates Matrix Metalloproteinases in Traumatic Brain Injury

(2018) Angus G. Scrimgeour et al.   JOURNAL OF NEUROTRAUMA

Indispensable Amino Acid–Deficient Diets Induce Seizures in Ketogenic Diet–Fed Rodents, Demonstrating a Role for Amino Acid Balance in Dietary Treatments for Epilepsy

(2018) Dorothy W Gietzen et al.   JOURNAL OF NUTRITION

Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders

(2018) Katrin Augustin et al.   LANCET NEUROLOGY

Iron as a therapeutic target for Parkinson's disease

(2018) Caroline Moreau et al.   MOVEMENT DISORDERS

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

(2018) Seung Pil Yun et al.   NATURE MEDICINE

Epigenetic regulation of brain region-specific microglia clearance activity

(2018) Pinar Ayata et al.   NATURE NEUROSCIENCE

Lactate in the brain: from metabolic end-product to signalling molecule

(2018) Pierre J. Magistretti et al.   NATURE REVIEWS NEUROSCIENCE

Effects of Vitamin D3 on the NADPH Oxidase and Matrix Metalloproteinase 9 in an Animal Model of Global Cerebral Ischemia

(2018) Milica Velimirović et al.   Oxidative Medicine and Cellular Longevity

Disruption of the Circadian Clock Alters Antioxidative Defense via the SIRT1-BMAL1 Pathway in 6-OHDA-Induced Models of Parkinson’s Disease

(2018) Yali Wang et al.   Oxidative Medicine and Cellular Longevity

Linking the Gut Microbiota to a Brain Neurotransmitter

(2018) Kelly G. Jameson et al.   TRENDS IN NEUROSCIENCES

The pharmacological perturbation of brain zinc impairs BDNF-related signaling and the cognitive performances of young mice

(2018) Valerio Frazzini et al.   Scientific Reports

Oxytosis/Ferroptosis—(Re-) Emerging Roles for Oxidative Stress-Dependent Non-apoptotic Cell Death in Diseases of the Central Nervous System

(2018) Jan Lewerenz et al.   Frontiers in Neuroscience

Which of the branched-chain amino acids increases cerebral blood flow in hepatic encephalopathy? A double-blind randomized trial

(2018) Fernando Gomes Romeiro et al.   NeuroImage-Clinical

13 reasons why the brain is susceptible to oxidative stress

(2018) James Nathan Cobley et al.   Redox Biology

A pectin from fruits of Lycium barbarum L. decreases β-amyloid peptide production through modulating APP processing

(2018) Lishuang Zhou et al.   CARBOHYDRATE POLYMERS

A Neural Circuit for Gut-Induced Reward

(2018) Wenfei Han et al.   CELL

Use of cooking oils in a 2:1 ratio classical ketogenic diet for intractable pediatric epilepsy: Long-term effectiveness and tolerability

(2018) Hsiu-Fen Lee et al.   EPILEPSY RESEARCH

Sodium Butyrate Improves Memory Function in an Alzheimer's Disease Mouse Model When Administered at an Advanced Stage of Disease Progression

(2018) Nambirajan Govindarajan et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuroprotective Effects of a Specific Multi-Nutrient Intervention Against Aβ42-Induced Toxicity in Rats

(2018) Martijn C. de Wilde et al.   JOURNAL OF ALZHEIMERS DISEASE

Vitamin D protects dopaminergic neurons against neuroinflammation and oxidative stress in hemiparkinsonian rats

(2018) Ludmila A R Lima et al.   Journal of Neuroinflammation

Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing

(2018) Barry Boland et al.   NATURE REVIEWS DRUG DISCOVERY

Neuroprotective effects of genistein on SH-SY5Y cells overexpressing A53T mutant α-synuclein

(2018) Sai Zhang et al.   Neural Regeneration Research

Post-stroke administration of omega-3 polyunsaturated fatty acids promotes neurovascular restoration after ischemic stroke in mice: Efficacy declines with aging

(2018) Xiaoyan Jiang et al.   NEUROBIOLOGY OF DISEASE

Sodium butyrate improves memory and modulates the activity of histone deacetylases in aged rats after the administration of d-galactose

(2018) Michelle Lima Garcez et al.   EXPERIMENTAL GERONTOLOGY

Pharmacoepigenomic Interventions as Novel Potential Treatments for Alzheimer’s and Parkinson’s Diseases

(2018) Oscar Teijido et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mediterranean diet adherence is related to reduced probability of prodromal Parkinson's disease

(2018) Maria I. Maraki et al.   MOVEMENT DISORDERS

Lifestyle interventions to prevent cognitive impairment, dementia and Alzheimer disease

(2018) Miia Kivipelto et al.   Nature Reviews Neurology

Beneficial effects of n-3 polyunsaturated fatty acids administration in a partial lesion model of Parkinson's disease: The role of glia and NRf2 regulation

(2018) Sara Hernando et al.   NEUROBIOLOGY OF DISEASE

Genetically Engineered Resveratrol-Enriched Rice Inhibits Neuroinflammation in Lipopolysaccharide-Activated BV2 Microglia Via Downregulating Mitogen-Activated Protein Kinase-Nuclear Factor Kappa B Signaling Pathway

(2018) Lalita Subedi et al.   Oxidative Medicine and Cellular Longevity

Gallic acid disruption of Aβ1–42 aggregation rescues cognitive decline of APP/PS1 double transgenic mouse

(2018) Mei Yu et al.   NEUROBIOLOGY OF DISEASE

Metabolic shifts in residual breast cancer drive tumor recurrence

(2017) Kristina M. Havas et al.   JOURNAL OF CLINICAL INVESTIGATION

Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease

(2017) Charbel Moussa et al.   Journal of Neuroinflammation

Tau-mediated iron export prevents ferroptotic damage after ischemic stroke

(2017) Q-z Tuo et al.   MOLECULAR PSYCHIATRY

A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice

(2017) D P Ryan et al.   MOLECULAR PSYCHIATRY

Interactions between the microbiota, immune and nervous systems in health and disease

(2017) Thomas C Fung et al.   NATURE NEUROSCIENCE

AMPK: guardian of metabolism and mitochondrial homeostasis

(2017) Sébastien Herzig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Vitamin D Receptor Activation Influences NADPH Oxidase (NOX2) Activity and Protects against Neurological Deficits and Apoptosis in a Rat Model of Traumatic Brain Injury

(2017) Changmeng Cui et al.   Oxidative Medicine and Cellular Longevity

Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models

(2017) Egle Cekanaviciute et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice

(2017) Kerstin Berer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The relationship between obesity and cognitive health and decline

(2017) Louise Dye et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Adherence to a Healthy Nordic Diet and Risk of Stroke

(2017) Camilla Plambeck Hansen et al.   STROKE

Neuronal SIRT1 (Silent Information Regulator 2 Homologue 1) Regulates Glycolysis and Mediates Resveratrol-Induced Ischemic Tolerance

(2017) Kevin B. Koronowski et al.   STROKE

AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species

(2017) Rebecca C. Rabinovitch et al.   Cell Reports

Association of Lithium in Drinking Water With the Incidence of Dementia

(2017) Lars Vedel Kessing et al.   JAMA Psychiatry

Objective assessment of dietary patterns by use of metabolic phenotyping: a randomised, controlled, crossover trial

(2017) Isabel Garcia-Perez et al.   Lancet Diabetes & Endocrinology

Ginkgo biloba extract improved cognitive and neurological functions of acute ischaemic stroke: a randomised controlled trial

(2017) Shanshan Li et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration

(2017) William Sealy Hambright et al.   Redox Biology

Can Nutrients Prevent or Delay Onset of Alzheimer's Disease?

(2017) Patrick J.G.H. Kamphuis et al.   JOURNAL OF ALZHEIMERS DISEASE

Expression pattern of NMDA receptors reveals antiepileptic potential of apigenin 8-C-glucoside and chlorogenic acid in pilocarpine induced epileptic mice

(2016) G. Smilin Bell Aseervatham et al.   BIOMEDICINE & PHARMACOTHERAPY

Brain injury induces specific changes in the caecal microbiota of mice via altered autonomic activity and mucoprotein production

(2016) A. Houlden et al.   BRAIN BEHAVIOR AND IMMUNITY

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

Sensory Neurons that Detect Stretch and Nutrients in the Digestive System

(2016) Erika K. Williams et al.   CELL

Resveratrol as a Potential Therapeutic Candidate for the Treatment and Management of Alzheimer';s Disease

(2016) Nady Braidy et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Gut microbiota in early pediatric multiple sclerosis: a case−control study

(2016) H. Tremlett et al.   EUROPEAN JOURNAL OF NEUROLOGY

Adult microbiota-deficient mice have distinct dendritic morphological changes: differential effects in the amygdala and hippocampus

(2016) Pauline Luczynski et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Chitosan oligosaccharides alleviate cognitive deficits in an amyloid-β1–42-induced rat model of Alzheimer's disease

(2016) Shiliang Jia et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Apigenin-7-O-β-D-(-6''-p-coumaroyl)-Glucopyranoside Treatment Elicits Neuroprotective Effect against Experimental Ischemic Stroke

(2016) Min Cai et al.   International Journal of Biological Sciences

Lithium-induced neuroprotection in stroke involves increased miR-124 expression, reduced RE1-silencing transcription factor abundance and decreased protein deubiquitination by GSK3β inhibition-independent pathways

(2016) Thorsten R Doeppner et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Reduced acute neuroinflammation and improved functional recovery after traumatic brain injury by α-linolenic acid supplementation in mice

(2016) Abhishek Desai et al.   Journal of Neuroinflammation

Microbiota Dysbiosis Controls the Neuroinflammatory Response after Stroke

(2016) V. Singh et al.   JOURNAL OF NEUROSCIENCE

Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 trial

(2016) Rafael de la Torre et al.   LANCET NEUROLOGY

Therapeutic Effects of Quercetin on Inflammation, Obesity, and Type 2 Diabetes

(2016) Shuang Chen et al.   MEDIATORS OF INFLAMMATION

Vitamin D interacts with Esr1 and Igf1 to regulate molecular pathways relevant to Alzheimer’s disease

(2016) Véréna Landel et al.   Molecular Neurodegeneration

Lithium suppression of tau induces brain iron accumulation and neurodegeneration

(2016) P Lei et al.   MOLECULAR PSYCHIATRY

Metabolic acceleration and the evolution of human brain size and life history

(2016) Herman Pontzer et al.   NATURE

Zinc contributes to acute cerebral ischemia-induced blood–brain barrier disruption

(2016) Zhifeng Qi et al.   NEUROBIOLOGY OF DISEASE

Maternal fat-soluble vitamins, brain development, and regulation of feeding behavior: an overview of research

(2016) Diana Sánchez-Hernández et al.   NUTRITION RESEARCH

Dietary Approaches to Stop Hypertension Diet and Incidence of Stroke

(2016) Susanna C. Larsson et al.   STROKE

Neurological Disease as a Failure of Brain–Immune Crosstalk: The Multiple Faces of Neuroinflammation

(2016) Michal Schwartz et al.   TRENDS IN IMMUNOLOGY

Curcumin modulates cell death and is protective in Huntington’s disease model

(2016) Anjalika Chongtham et al.   Scientific Reports

A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms

(2016) In Young Choi et al.   Cell Reports

MIND diet associated with reduced incidence of Alzheimer's disease

(2015) Martha Clare Morris et al.   Alzheimers & Dementia

MIND diet slows cognitive decline with aging

(2015) Martha Clare Morris et al.   Alzheimers & Dementia

The Nordic diet and cognition – The DR's EXTRA Study

(2015) Reija Männikkö et al.   BRITISH JOURNAL OF NUTRITION

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Colonic bacterial composition in Parkinson's disease

(2015) Ali Keshavarzian et al.   MOVEMENT DISORDERS

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Efficacy of the Ketogenic Diet for the Treatment of Refractory Childhood Epilepsy: Cerebrospinal Fluid Neurotransmitters and Amino Acid Levels

(2015) Andrea Sariego-Jamardo et al.   PEDIATRIC NEUROLOGY

Role of the gluten-free diet on neurological-EEG findings and sleep disordered breathing in children with celiac disease

(2015) P. Parisi et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

A glucan isolated from flowers of Lonicera japonica Thunb. inhibits aggregation and neurotoxicity of Aβ42

(2014) Peipei Wang et al.   CARBOHYDRATE POLYMERS

Fasting: Molecular Mechanisms and Clinical Applications

(2014) Valter D. Longo et al.   Cell Metabolism

Aberrant expression of miR-218 and miR-204 in human mesial temporal lobe epilepsy and hippocampal sclerosis-Convergence on axonal guidance

(2014) Sanne S. Kaalund et al.   EPILEPSIA

Intermittent fasting attenuates inflammasome activity in ischemic stroke

(2014) David Yang-Wei Fann et al.   EXPERIMENTAL NEUROLOGY

Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury

(2014) Hai-tao Zhu et al.   Journal of Neuroinflammation

Docosahexaenoic Acid Reduces ER Stress and Abnormal Protein Accumulation and Improves Neuronal Function Following Traumatic Brain Injury

(2014) G. Begum et al.   JOURNAL OF NEUROSCIENCE

Nutrient patterns and brain biomarkers of Alzheimer’s disease in cognitively normal individuals

(2014) V. Berti et al.   Journal of Nutrition Health & Aging

The role of iron in brain ageing and neurodegenerative disorders

(2014) Roberta J Ward et al.   LANCET NEUROLOGY

Amyloid-beta (Aβ1-42)-induced paralysis inCaenorhabditis elegansis inhibited by the polyphenol quercetin through activation of protein degradation pathways

(2014) Charlotte Regitz et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Gut microbiota are related to Parkinson's disease and clinical phenotype

(2014) Filip Scheperjans et al.   MOVEMENT DISORDERS

MicroRNAs in myocardial infarction

(2014) Reinier A. Boon et al.   Nature Reviews Cardiology

(−)-Epigallocatechin Gallate Protects Against Cerebral Ischemia-Induced Oxidative Stress via Nrf2/ARE Signaling

(2014) Jie Han et al.   NEUROCHEMICAL RESEARCH

Vitamin D and the risk of dementia and Alzheimer disease

(2014) T. J. Littlejohns et al.   NEUROLOGY

Relation of DASH- and Mediterranean-like dietary patterns to cognitive decline in older persons

(2014) C. C. Tangney et al.   NEUROLOGY

Increasing Maternal or Post-Weaning Folic Acid Alters Gene Expression and Moderately Changes Behavior in the Offspring

(2014) Subit Barua et al.   PLoS One

Resveratrol protects astrocytes against traumatic brain injury through inhibiting apoptotic and autophagic cell death

(2014) C-J Lin et al.   Cell Death & Disease

Appropriate nutrient supplementation in celiac disease

(2013) Roberta Caruso et al.   ANNALS OF MEDICINE

Mediterranean diet, stroke, cognitive impairment, and depression: A meta-analysis

(2013) Theodora Psaltopoulou et al.   ANNALS OF NEUROLOGY

Resveratrol improves learning and memory in normally aged mice through microRNA-CREB pathway

(2013) Yong-Na Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Jmjd3 is essential for the epigenetic modulation of microglia phenotypes in the immune pathogenesis of Parkinson’s disease

(2013) Y Tang et al.   CELL DEATH AND DIFFERENTIATION

Neuroprotective, Anti-Amyloidogenic and Neurotrophic Effects of Apigenin in an Alzheimer’s Disease Mouse Model

(2013) Le Zhao et al.   MOLECULES

Review: The role of vitamin D in nervous system health and disease

(2013) G. C. DeLuca et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Galactooligosaccharide improves the animal survival and alleviates motor neuron death in SOD1G93A mouse model of amyotrophic lateral sclerosis

(2013) L. Song et al.   NEUROSCIENCE

Genistein antagonizes inflammatory damage induced by β-amyloid peptide in microglia through TLR4 and NF-κB

(2013) Xin Zhou et al.   NUTRITION

Efficacy and Safety of Curcumin in Major Depressive Disorder: A Randomized Controlled Trial

(2013) Jayesh Sanmukhani et al.   PHYTOTHERAPY RESEARCH

Efficacy and Safety of Standardized Extract ofTrigonella foenum-graecumL Seeds as an Adjuvant to L-Dopa in the Management of Patients with Parkinson's Disease

(2013) J. Nathan et al.   PHYTOTHERAPY RESEARCH

Oxidative modification of lipoic acid by HNE in Alzheimer disease brain

(2013) Sarita S. Hardas et al.   Redox Biology

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Neuroprotective effects of oral gallic acid against oxidative stress induced by 6-hydroxydopamine in rats

(2012) Mohammad Taghi Mansouri et al.   FOOD CHEMISTRY

Resveratrol ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice

(2012) Heng Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

FOXO3-induced reactive oxygen species are regulated by BCL2L11 (Bim) and SESN3

(2012) J. Hagenbuchner et al.   JOURNAL OF CELL SCIENCE

Neuroprotective effect of (–)-epigallocatechin-3-gallate in rats when administered pre- or post-traumatic brain injury

(2012) Tatsuki Itoh et al.   JOURNAL OF NEURAL TRANSMISSION

AMP Kinase Activation Mitigates Dopaminergic Dysfunction and Mitochondrial Abnormalities in Drosophila Models of Parkinson's Disease

(2012) C.-H. Ng et al.   JOURNAL OF NEUROSCIENCE

Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study

(2012) Julie A. Mattison et al.   NATURE

Epigenetic mechanisms in neurological disease

(2012) Mira Jakovcevski et al.   NATURE MEDICINE

A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease

(2012) Yoshihiro Kashiwaya et al.   NEUROBIOLOGY OF AGING

Neuroprotection by the soy isoflavone, genistein, via inhibition of mitochondria-dependent apoptosis pathways and reactive oxygen induced-NF-κB activation in a cerebral ischemia mouse model

(2012) Yisong Qian et al.   NEUROCHEMISTRY INTERNATIONAL

The Ketogenic Diet as a Treatment Paradigm for Diverse Neurological Disorders

(2012) Carl E. Stafstrom et al.   Frontiers in Pharmacology

α-Synuclein Neuropathology is Controlled by Nuclear Hormone Receptors and Enhanced by Docosahexaenoic Acid in A Mouse Model for Parkinson's Disease

(2011) Eugenia Yakunin et al.   BRAIN PATHOLOGY

Elevated labile Cu is associated with oxidative pathology in Alzheimer disease

(2011) Simon A. James et al.   FREE RADICAL BIOLOGY AND MEDICINE

Preventive effect of gastrodin on cognitive decline after cardiac surgery with cardiopulmonary bypass: A double-blind, randomized controlled study

(2011) Zhao Zhang et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Drug-Resistant Epilepsy

(2011) Patrick Kwan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Promise of resveratrol for easing status epilepticus and epilepsy

(2011) Ashok K. Shetty   PHARMACOLOGY & THERAPEUTICS

The combined effects of exercise and foods in preventing neurological and cognitive disorders

(2011) Fernando Gomez-Pinilla   PREVENTIVE MEDICINE

Accruing evidence on benefits of adherence to the Mediterranean diet on health: an updated systematic review and meta-analysis

(2010) Francesco Sofi et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease

(2010) James A. Duce et al.   CELL

Metabolism and Circadian Rhythms—Implications for Obesity

(2010) Oren Froy   ENDOCRINE REVIEWS

Identification of the 100 richest dietary sources of polyphenols: an application of the Phenol-Explorer database

(2010) J Pérez-Jiménez et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Acute oxidative stress and systemic Nrf2 activation by the ketogenic diet

(2010) Julie B. Milder et al.   NEUROBIOLOGY OF DISEASE

Whole Body Hypothermia and Oxidative Stress in Babies With Hypoxic-Ischemic Brain Injury

(2010) Serafina Perrone et al.   PEDIATRIC NEUROLOGY

Gut Microbiota in Health and Disease

(2010) Inna Sekirov et al.   PHYSIOLOGICAL REVIEWS

Age and energy intake interact to modify cell stress pathways and stroke outcome

(2009) Thiruma V. Arumugam et al.   ANNALS OF NEUROLOGY

The protective effect of the ketogenic diet on traumatic brain injury-induced cell death in juvenile rats

(2009) Zhi-Gang Hu et al.   BRAIN INJURY

Hepatotoxicity from green tea: a review of the literature and two unpublished cases

(2009) Gabriela Mazzanti et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

PGC-1α and PGC-1β Regulate Mitochondrial Density in Neurons

(2009) Przemyslaw Wareski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Brain-derived neurotrophic factor in neurodegenerative diseases

(2009) Chiara Zuccato et al.   Nature Reviews Neurology

Zinc in the physiology and pathology of the CNS

(2009) Stefano L. Sensi et al.   NATURE REVIEWS NEUROSCIENCE

Evolution of the neocortex: a perspective from developmental biology

(2009) Pasko Rakic   NATURE REVIEWS NEUROSCIENCE

Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans

(2008) Katherine A. Steinkraus et al.   AGING CELL

A randomized trial of classical and medium-chain triglyceride ketogenic diets in the treatment of childhood epilepsy

(2008) Elizabeth G. Neal et al.   EPILEPSIA

Fasting is neuroprotective following traumatic brain injury

(2008) Laurie M. Davis et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Advances in Celiac Disease and Gluten-Free Diet

(2008) Mary M. Niewinski   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

Mitochondria in Neuroplasticity and Neurological Disorders

(2008) Mark P. Mattson et al.   NEURON

Docosahexaenoic acid dietary supplementation enhances the effects of exercise on synaptic plasticity and cognition

(2008) A. Wu et al.   NEUROSCIENCE

Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer

(2008) S. Varambally et al.   SCIENCE

Activation of Pannexin-1 Hemichannels Augments Aberrant Bursting in the Hippocampus

(2008) R. J. Thompson et al.   SCIENCE

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE