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Title
The Role of Apolipoprotein E Isoforms in Alzheimer’s Disease
Authors
Keywords
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Journal
JOURNAL OF ALZHEIMERS DISEASE
Volume 68, Issue 2, Pages 459-471
Publisher
IOS Press
Online
2019-02-13
DOI
10.3233/jad-180740
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Note: Only part of the references are listed.- The effects of the TOMM40 poly-T alleles on Alzheimer's disease phenotypes
- (2018) Ornit Chiba-Falek et al. Alzheimers & Dementia
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- (2017) Veena Theendakara et al. MOLECULAR NEUROBIOLOGY
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- (2017) Yang Shi et al. NATURE
- Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity
- (2017) Vincenzo Sorrentino et al. NATURE
- APOE genotype and early β-amyloid accumulation in older adults without dementia
- (2017) Yen Ying Lim et al. NEUROLOGY
- Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes
- (2017) Na Zhao et al. NEURON
- Quantifying the accretion of hyperphosphorylated tau in the locus coeruleus and dorsal raphe nucleus: the pathological building blocks of early Alzheimer's disease
- (2017) A. J. Ehrenberg et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Differential associations of plasma lipids with incident dementia and dementia subtypes in the 3C Study: A longitudinal, population-based prospective cohort study
- (2017) Sabrina Schilling et al. PLOS MEDICINE
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- (2017) Julie M. Zissimopoulos et al. JAMA Neurology
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- (2017) Jon Valla et al. JOURNAL OF ALZHEIMERS DISEASE
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- (2017) Shan Liu et al. Scientific Reports
- CSF tau is associated with impaired cortical plasticity, cognitive decline and astrocyte survival only in APOE4-positive Alzheimer’s disease
- (2017) Giacomo Koch et al. Scientific Reports
- Apolipoprotein E as a Therapeutic Target in Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence
- (2016) Yu Yamazaki et al. CNS DRUGS
- New Genetic Approaches to AD: Lessons from APOE-TOMM40 Phylogenetics
- (2016) Michael W. Lutz et al. Current Neurology and Neuroscience Reports
- Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease
- (2016) Claudio Villegas-Llerena et al. CURRENT OPINION IN NEUROBIOLOGY
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- Genetic Restoration of Plasma ApoE Improves Cognition and Partially Restores Synaptic Defects in ApoE-Deficient Mice
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- Apolipoprotein E*4 (APOE*4) Genotype Is Associated with Altered Levels of Glutamate Signaling Proteins and Synaptic Coexpression Networks in the Prefrontal Cortex in Mild to Moderate Alzheimer Disease
- (2016) Robert A. Sweet et al. MOLECULAR & CELLULAR PROTEOMICS
- Apolipoprotein E lipoprotein particles inhibit amyloid-β uptake through cell surface heparan sulphate proteoglycan
- (2016) Yuan Fu et al. Molecular Neurodegeneration
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- (2016) Jose M. Farfel et al. NEUROBIOLOGY OF AGING
- Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes
- (2016) Won-Suk Chung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2016) Kaushik Ghosal et al. PLoS One
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- Epidemiology of Alzheimer Disease
- (2013) R. Mayeux et al. Cold Spring Harbor Perspectives in Medicine
- Pathogenesis and Disease-modifying Therapy in Alzheimer's Disease: The Flat Line of Progress
- (2012) Rudy J. Castellani et al. ARCHIVES OF MEDICAL RESEARCH
- Plasma Signaling Proteins in Persons at Genetic Risk for Alzheimer Disease
- (2012) John M. Ringman et al. ARCHIVES OF NEUROLOGY
- Cholesterol and Alzheimer's disease: A still poorly understood correlation
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- (2012) T. Kanekiyo et al. JOURNAL OF NEUROSCIENCE
- Apolipoprotein E Sets the Stage: Response to Injury Triggers Neuropathology
- (2012) Robert W. Mahley et al. NEURON
- Reduction of low-density lipoprotein receptor-related protein (LRP1) in hippocampal neurons does not proportionately reduce, or otherwise alter, amyloid deposition in APPswe/PS1dE9 transgenic mice
- (2012) Guilian Xu et al. Alzheimers Research & Therapy
- Structure-dependent Impairment of Intracellular Apolipoprotein E4 Trafficking and Its Detrimental Effects Are Rescued by Small-molecule Structure Correctors
- (2011) Jens Brodbeck et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
- (2011) Eric Karran et al. NATURE REVIEWS DRUG DISCOVERY
- Mechanism mediating oligomeric Aβ clearance by naïve primary microglia
- (2011) Cheng-Ning Yang et al. NEUROBIOLOGY OF DISEASE
- Human apoE Isoforms Differentially Regulate Brain Amyloid- Peptide Clearance
- (2011) J. M. Castellano et al. Science Translational Medicine
- Review Article: Genetics of Alzheimer Disease
- (2010) Lynn M. Bekris et al. JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY
- Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Mediates Neuronal Aβ42 Uptake and Lysosomal Trafficking
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- Decreased Clearance of CNS -Amyloid in Alzheimer's Disease
- (2010) K. G. Mawuenyega et al. SCIENCE
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- (2009) S. B. Dumanis et al. JOURNAL OF NEUROSCIENCE
- Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
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- Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
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- Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy
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- The dorsal raphe nucleus shows phospho-tau neurofibrillary changes before the transentorhinal region in Alzheimer's disease. A precocious onset?
- (2009) L. T. Grinberg et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain
- (2009) K. Ghosal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- apoE isoform–specific disruption of amyloid β peptide clearance from mouse brain
- (2008) Rashid Deane et al. JOURNAL OF CLINICAL INVESTIGATION
- Impact of Apolipoprotein E (ApoE) Polymorphism on Brain ApoE Levels
- (2008) D. R. Riddell et al. JOURNAL OF NEUROSCIENCE
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