Renal microvascular endothelial cell responses in sepsis-induced acute kidney injury

Single-Cell Transcriptome Atlas of Murine Endothelial Cells

(2020) Joanna Kalucka et al.   CELL

Endothelial Glycocalyx

(2020) Jan Jedlicka et al.   CRITICAL CARE CLINICS

Platelet Activation and Endothelial Cell Dysfunction

(2020) Tom van der Poll et al.   CRITICAL CARE CLINICS

A Review on Microvascular Hemodynamics

(2020) Carlos J. Munoz et al.   CRITICAL CARE CLINICS

Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study

(2020) Kristina E Rudd et al.   LANCET

Endothelial Scaffolding Protein ENH (Enigma Homolog Protein) Promotes PHLPP2 (Pleckstrin Homology Domain and Leucine-Rich Repeat Protein Phosphatase 2)-Mediated Dephosphorylation of AKT1 and eNOS (Endothelial NO Synthase) Promoting Vascular Remodeling

(2020) Jiaqi Huang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Platelets docking to VWF prevent leaks during leukocyte extravasation by stimulating Tie-2

(2020) Laura J. Braun et al.   BLOOD

The expression of thioredoxin-1 and inflammatory cytokines in patients with sepsis

(2020) Ruifei Shao et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Protective Effects of Recombinant Human Soluble Thrombomodulin on Lipopolysaccharide-Induced Acute Kidney Injury

(2020) Yuji Nozaki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Kinin B1 receptor: a potential therapeutic target in sepsis-induced vascular hyperpermeability

(2020) Stéphanie Ruiz et al.   Journal of Translational Medicine

Proteomic and interactomic insights into the molecular basis of cell functional diversity

(2020) Isabell Bludau et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The application of omic technologies to research in sepsis-associated acute kidney injury

(2020) Denise Hasson et al.   PEDIATRIC NEPHROLOGY

It takes more than two to tango: mechanosignaling of the endothelial surface

(2020) Benedikt Fels et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Acute lung injury: The therapeutic role of Rho kinase inhibitors

(2020) Farshad Abedi et al.   PHARMACOLOGICAL RESEARCH

The Role of Circulating Cell-Free Hemoglobin in Sepsis-Associated Acute Kidney Injury

(2020) V. Eric Kerchberger et al.   SEMINARS IN NEPHROLOGY

Inflammaging and Complement System: A Link Between Acute Kidney Injury and Chronic Graft Damage

(2020) Rossana Franzin et al.   Frontiers in Immunology

The integrin linked kinase is required for chemokine-triggered high affinity conformation of neutrophil β2-integrin LFA1

(2020) Andreas Margraf et al.   BLOOD

Mortality and host response aberrations associated with transient and persistent acute kidney injury in critically ill patients with sepsis: a prospective cohort study

(2020) Fabrice Uhel et al.   INTENSIVE CARE MEDICINE

Impaired angiotensin II type 1 receptor signaling contributes to sepsis induced acute kidney injury.

(2020) Daniel E. Leisman et al.   KIDNEY INTERNATIONAL

Permeability of the Endothelial Barrier: Identifying and Reconciling Controversies

(2020) Lena Claesson-Welsh et al.   TRENDS IN MOLECULAR MEDICINE

Endothelium structure and function in kidney health and disease

(2019) Noemie Jourde-Chiche et al.   Nature Reviews Nephrology

Deregulated renal magnesium transport during lipopolysaccharide-induced acute kidney injury in mice

(2019) Manuel Meurer et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis

(2019) Christopher W. Seymour et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Mitochondria in Sepsis-Induced AKI

(2019) Jian Sun et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Neutrophil activation in septic acute kidney injury: A post‐hoc analysis of the FINNAKI study

(2019) Sanna Törnblom et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Epigenetic Determinants of Flow-Mediated Vascular Endothelial Gene Expression

(2019) Kyung Ha Ku et al.   HYPERTENSION

Identification of LPS-Activated Endothelial Subpopulations With Distinct Inflammatory Phenotypes and Regulatory Signaling Mechanisms

(2019) Erna-Zulaikha Dayang et al.   Frontiers in Immunology

Which Multicenter Randomized Controlled Trials in Critical Care Medicine Have Shown Reduced Mortality? A Systematic Review

(2019) Carlos A. Santacruz et al.   CRITICAL CARE MEDICINE

Human kidney organoids: progress and remaining challenges

(2019) Ryuichi Nishinakamura   Nature Reviews Nephrology

Sepsis hysteria: excess hype and unrealistic expectations

(2019) Mervyn Singer et al.   LANCET

Acute kidney injury

(2019) Claudio Ronco et al.   LANCET

The in vivo endothelial cell translatome is highly heterogeneous across vascular beds

(2019) Audrey C. A. Cleuren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Renal Medullary Hypoxia: A New Therapeutic Target for Septic Acute Kidney Injury?

(2019) Yugeesh R. Lankadeva et al.   SEMINARS IN NEPHROLOGY

Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis

(2019) Alejandro Gómez Toledo et al.   Nature Communications

Combining laser microdissection and microRNA expression profiling to unmask microRNA signatures in complex tissues

(2019) Susanna Skalicky et al.   BIOTECHNIQUES

Stem cell-derived kidney organoids: engineering the vasculature

(2019) Marije Koning et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Biomarkers and Precision Medicine

(2019) Aartik Sarma et al.   CRITICAL CARE CLINICS

Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation

(2019) Sébastien J. Dumas et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Lipopolysaccharide induces filtrate leakage from renal tubular lumina into the interstitial space via a proximal tubular Toll-like receptor 4–dependent pathway and limits sensitivity to fluid therapy in mice

(2019) Daisuke Nakano et al.   KIDNEY INTERNATIONAL

Current gaps in sepsis immunology: new opportunities for translational research

(2019) Ignacio Rubio et al.   LANCET INFECTIOUS DISEASES

Molecular determinants of nephron vascular specialization in the kidney

(2019) David M. Barry et al.   Nature Communications

Experimental human endotoxemia as a model of systemic inflammation

(2018) Dirk van Lier et al.   BIOCHIMIE

Endothelial cell protein C receptor-dependent signaling

(2018) Usha R. Pendurthi et al.   CURRENT OPINION IN HEMATOLOGY

MicroRNAs in endothelial cell homeostasis and vascular disease

(2018) Carlos Fernández-Hernando et al.   CURRENT OPINION IN HEMATOLOGY

Ligand-specific binding forces of LFA-1 and Mac-1 in neutrophil adhesion and crawling

(2018) Ning Li et al.   MOLECULAR BIOLOGY OF THE CELL

Paradigms of acute kidney injury in the intensive care setting

(2018) John A. Kellum et al.   Nature Reviews Nephrology

Micro- and Macrocirculatory Changes During Sepsis and Septic Shock in a Rat Model

(2018) Tianfeng Hua et al.   SHOCK

Early Heterogenic Response of Renal Microvasculature to Hemorrhagic Shock/Resuscitation and the Influence of NF-κB Pathway Blockade

(2018) Rui Yan et al.   SHOCK

Apolipoprotein M Protects Lipopolysaccharide-Treated Mice from Death and Organ Injury

(2018) Koichi Tsuneyama et al.   THROMBOSIS AND HAEMOSTASIS

Characterization of immune cell, endothelial, and renal responses upon experimental human endotoxemia

(2018) Eveline P. van Poelgeest et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Partial Deletion of Tie2 Affects Microvascular Endothelial Responses to Critical Illness in a Vascular Bed and Organ-Specific Way

(2018) Rianne M. Jongman et al.   SHOCK

Long-Term Effects of Experimental Human Endotoxemia on Immune Cell Function

(2018) Yessica Alina Rodriguez-Rosales et al.   SHOCK

Identification of Acute Kidney Injury Sub-phenotypes with Differing Molecular Signatures and Response to Vasopressin Therapy

(2018) Pavan K Bhatraju et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The role of biomarkers of endothelial activation in predicting morbidity and mortality in patients with severe sepsis and septic shock in intensive care: A prospective observational study

(2018) Yingying Fang et al.   THROMBOSIS RESEARCH

Acute kidney injury in sepsis

(2017) Rinaldo Bellomo et al.   INTENSIVE CARE MEDICINE

The Angiopoietin-Tie2 Signaling Axis in Systemic Inflammation

(2017) Samir M. Parikh   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renal perfusion in sepsis: from macro- to microcirculation

(2017) Emiel Hendrik Post et al.   KIDNEY INTERNATIONAL

The functions and unique features of long intergenic non-coding RNA

(2017) Julia D. Ransohoff et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Metabolic reprogramming and tolerance during sepsis-induced AKI

(2017) Hernando Gómez et al.   Nature Reviews Nephrology

A review of the role of immune cells in acute kidney injury

(2017) Anthony Bonavia et al.   PEDIATRIC NEPHROLOGY

Organ-Specific Differences in Endothelial Permeability-Regulating Molecular Responses in Mouse and Human Sepsis

(2017) Adnan Aslan et al.   SHOCK

Molecular differences in susceptibility of the kidney to sepsis-induced kidney injury

(2017) Martin Matejovic et al.   BMC Nephrology

Incidence, timing and outcome of AKI in critically ill patients varies with the definition used and the addition of urine output criteria

(2017) J. Koeze et al.   BMC Nephrology

Vascular Endothelial (VE)-Cadherin, Endothelial Adherens Junctions, and Vascular Disease

(2017) Maria Grazia Lampugnani et al.   Cold Spring Harbor Perspectives in Biology

Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study

(2017) Brendon P Scicluna et al.   Lancet Respiratory Medicine

MicroRNA Profiling Reveals Distinct Profiles for Tissue-Derived and Cultured Endothelial Cells

(2017) Suvi M. Kuosmanen et al.   Scientific Reports

Heparanase Is Essential for the Development of Acute Experimental Glomerulonephritis

(2016) Marjolein Garsen et al.   AMERICAN JOURNAL OF PATHOLOGY

Urinary Glycosaminoglycans Predict Outcomes in Septic Shock and Acute Respiratory Distress Syndrome

(2016) Eric P. Schmidt et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The use of the soluble adhesion molecules sE-selectin, sICAM-1, sVCAM-1, sPECAM-1 and their ligands CD11a and CD49d as diagnostic and prognostic biomarkers in septic and critically ill non-septic ICU patients

(2016) Anders G. Kjaergaard et al.   APMIS

Use of Biotelemetry to Define Physiology-Based Deterioration Thresholds in a Murine Cecal Ligation and Puncture Model of Sepsis

(2016) Anthony J. Lewis et al.   CRITICAL CARE MEDICINE

Sphingosine-1-Phosphate Signaling in Endothelial Disorders

(2016) Teresa Sanchez   Current Atherosclerosis Reports

Sepsis-induced acute kidney injury

(2016) Hernando Gómez et al.   Current Opinion in Critical Care

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Plasma syndecan-1 levels identify a cohort of patients with severe sepsis at high risk for intubation after large-volume intravenous fluid resuscitation

(2016) Michael A. Puskarich et al.   JOURNAL OF CRITICAL CARE

Survival advantage depends on cecal volume rather than cecal length in a mouse model of cecal ligation and puncture

(2016) Tianzhang Song et al.   JOURNAL OF SURGICAL RESEARCH

Mechanisms and regulation of endothelial VEGF receptor signalling

(2016) Michael Simons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Current Murine Models of Sepsis

(2016) Anthony J. Lewis et al.   Surgical Infections

Treatment With Human Wharton's Jelly-Derived Mesenchymal Stem Cells Attenuates Sepsis-Induced Kidney Injury, Liver Injury, and Endothelial Dysfunction

(2016) José M. Cóndor et al.   Stem Cells Translational Medicine

Interstitial pericytes decrease in aged mouse kidneys

(2015) Ania Stefanska et al.   Aging-US

Hydroxyethyl starch 130/0.4 decreases inflammation, neutrophil recruitment, and neutrophil extracellular trap formation

(2015) J. Rossaint et al.   BRITISH JOURNAL OF ANAESTHESIA

A primary role for kinin B1 receptor in inflammation, organ damage, and lethal thrombosis in a rat model of septic shock in diabetes

(2015) N Tidjane et al.   European Journal of Inflammation

Vascular endothelial cell Toll-like receptor pathways in sepsis

(2015) Samira Khakpour et al.   Innate Immunity

Ly6Chigh Monocytes Protect against Kidney Damage during Sepsis via a CX3CR1-Dependent Adhesion Mechanism

(2015) B. G. Chousterman et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Reduction of Tubular Flow Rate as a Mechanism of Oliguria in the Early Phase of Endotoxemia Revealed by Intravital Imaging

(2015) D. Nakano et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Application guide for omics approaches to cell signaling

(2015) Zhong Yao et al.   Nature Chemical Biology

Signalling scaffolds and local organization of cellular behaviour

(2015) Lorene K. Langeberg et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The emerging role of coagulation proteases in kidney disease

(2015) Thati Madhusudhan et al.   Nature Reviews Nephrology

Overexpression of toll-like receptor 2 in glomerular endothelial cells and podocytes in septic acute kidney injury mouse model

(2015) Yuan Peng et al.   RENAL FAILURE

Renal Endothelial Injury and Microvascular Dysfunction in Acute Kidney Injury

(2015) Sudhanshu Kumar Verma et al.   SEMINARS IN NEPHROLOGY

Sepsis-Associated Acute Kidney Injury: Macrohemodynamic and Microhemodynamic Alterations in the Renal Circulation

(2015) John R. Prowle et al.   SEMINARS IN NEPHROLOGY

Inflammation-Induced Increases in Plasma Endocan Levels are Associated With Endothelial Dysfunction in Humans in vivo

(2015) Laura AE Cox et al.   SHOCK

Biomarkers of Endothelial Activation Are Associated with Poor Outcome in Critical Illness

(2015) Carmen Mikacenic et al.   PLoS One

Endothelin-1 Activation of the Endothelin B Receptor Modulates Pulmonary Endothelial CX3CL1 and Contributes to Pulmonary Angiogenesis in Experimental Hepatopulmonary Syndrome

(2014) Junlan Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

Phosphatases and kinases as regulators of the endothelial barrier function

(2014) Verena Küppers et al.   CELL AND TISSUE RESEARCH

The Next Generation of Sepsis Clinical Trial Designs

(2014) Steven M. Opal et al.   CRITICAL CARE MEDICINE

Shear Stress-induced Redistribution of Vascular Endothelial-Protein-tyrosine Phosphatase (VE-PTP) in Endothelial Cells and Its Role in Cell Elongation

(2014) Kemala Isnainiasih Mantilidewi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Therapeutic translation in acute kidney injury: the epithelial/endothelial axis

(2014) Bruce A. Molitoris   JOURNAL OF CLINICAL INVESTIGATION

Adhesion Molecules Involved in Neutrophil Recruitment during Sepsis-Induced Acute Kidney Injury

(2014) Jan M. Herter et al.   Journal of Innate Immunity

Modulation of heparan sulfate in the glomerular endothelial glycocalyx decreases leukocyte influx during experimental glomerulonephritis

(2014) Angelique LWMM Rops et al.   KIDNEY INTERNATIONAL

Effects of protease activated receptor (PAR)2 blocking peptide on endothelin-1 levels in kidney tissues in endotoxemic rat mode

(2014) Subrina Jesmin et al.   LIFE SCIENCES

Immune cells in experimental acute kidney injury

(2014) Hye Ryoun Jang et al.   Nature Reviews Nephrology

Endothelial (NOS3 E298D) and inducible (NOS2 exon 22) nitric oxide synthase polymorphisms, as well as plasma NOx, influence sepsis development

(2014) Guadalupe Martin et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Organ-Specific Protection Against Lipopolysaccharide-Induced Vascular Leak Is Dependent on the Endothelial Protein C Receptor

(2013) Annette von Drygalski et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A mechanistic role for DNA methylation in endothelial cell (EC)-enriched gene expression: relationship with DNA replication timing

(2013) A. V. Shirodkar et al.   BLOOD

Critical role of sphingosine-1-phosphate receptor 2 (S1PR2) in acute vascular inflammation

(2013) G. Zhang et al.   BLOOD

Innovations in studying in vivo cell behavior and pharmacology in complex tissues – microvascular endothelial cells in the spotlight

(2013) Elise Langenkamp et al.   CELL AND TISSUE RESEARCH

The flow dependency of Tie2 expression in endotoxemia

(2013) Neng F. Kurniati et al.   INTENSIVE CARE MEDICINE

TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis

(2013) Chang Xu et al.   KIDNEY INTERNATIONAL

Distinct Contributions of TNF Receptor 1 and 2 to TNF-Induced Glomerular Inflammation in Mice

(2013) Anela Taubitz et al.   PLoS One

Heme Oxygenase 1 Modulates Thrombomodulin and Endothelial Protein C Receptor Levels to Attenuate Septic Kidney Injury

(2013) Kai Kang et al.   SHOCK

Biomarkers of Endothelial Cell Activation in Early Sepsis

(2013) Simon Skibsted et al.   SHOCK

Effect of P2X4 and P2X7 receptor antagonism on the pressure diuresis relationship in rats

(2013) Robert I. Menzies et al.   Frontiers in Physiology

Age-dependent Role of Microvascular Endothelial and Polymorphonuclear Cells in Lipopolysaccharide-induced Acute Kidney Injury

(2012) Francis M. Wulfert et al.   ANESTHESIOLOGY

E-Selectin Ligands as Mechanosensitive Receptors on Neutrophils in Health and Disease

(2012) S. D. Chase et al.   ANNALS OF BIOMEDICAL ENGINEERING

Angiopoietin-1 and Vascular Endothelial Growth Factor Regulation of Leukocyte Adhesion to Endothelial Cells

(2012) Hodan Ismail et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelin-1 and the kidney - beyond BP

(2012) Neeraj Dhaun et al.   BRITISH JOURNAL OF PHARMACOLOGY

Angiopoietin-2 may contribute to multiple organ dysfunction and death in sepsis*

(2012) Sascha David et al.   CRITICAL CARE MEDICINE

The Sphingosine-1-Phosphate Receptor S1PR1 Restricts Sprouting Angiogenesis by Regulating the Interplay between VE-Cadherin and VEGFR2

(2012) Konstantin Gaengel et al.   DEVELOPMENTAL CELL

The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis

(2012) Eric P Schmidt et al.   NATURE MEDICINE

Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus

(2012) Sapna Devi et al.   NATURE MEDICINE

Pharmacological targets in the renal peritubular microenvironment: Implications for therapy for sepsis-induced acute kidney injury

(2012) Philip R. Mayeux et al.   PHARMACOLOGY & THERAPEUTICS

Vascular Heterogeneity in the Kidney

(2012) Grietje Molema et al.   SEMINARS IN NEPHROLOGY

Adiponectin Diminishes Organ-Specific Microvascular Endothelial Cell Activation Associated With Sepsis

(2012) Matijs van Meurs et al.   SHOCK

Acute administration of recombinant Angiopoietin-1 ameliorates multiple-organ dysfunction syndrome and improves survival in murine sepsis

(2011) Sascha David et al.   CYTOKINE

Endotoxin Uptake by S1 Proximal Tubular Segment Causes Oxidative Stress in the Downstream S2 Segment

(2011) R. Kalakeche et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The glomerular endothelial cell coat is essential for glomerular filtration

(2011) Vincent Fridén et al.   KIDNEY INTERNATIONAL

Renal cytokine profile in an endotoxemic porcine model

(2010) A. GRANFELDT et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Multiplex cytokine profiling in patients with sepsis

(2010) SIMONA MERA et al.   APMIS

Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies

(2010) Inge A M de Graaf et al.   Nature Protocols

Heterogeneity in Endothelial Responsiveness to Cytokines, Molecular Causes, and Pharmacological Consequences

(2010) Grietje Molema   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Activation of endothelial intrinsic NF- B pathway impairs protein C anticoagulation mechanism and promotes coagulation in endotoxemic mice

(2009) D. Song et al.   BLOOD

Histopathology of septic shock induced acute kidney injury: apoptosis and leukocytic infiltration

(2009) Nicolas Lerolle et al.   INTENSIVE CARE MEDICINE

Skin Biopsies Demonstrate Site-Specific Endothelial Activation in Mouse Models of Sepsis

(2009) Nathan I. Shapiro et al.   JOURNAL OF VASCULAR RESEARCH

COMP-Angiopoietin-1 decreases lipopolysaccharide-induced acute kidney injury

(2009) Duk Hoon Kim et al.   KIDNEY INTERNATIONAL

Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system

(2009) Hellmut G. Augustin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Selective iNOS inhibition for the treatment of sepsis-induced acute kidney injury

(2009) Suzanne Heemskerk et al.   Nature Reviews Nephrology

PROTEASE-ACTIVATED RECEPTOR 2 BLOCKING PEPTIDE COUNTERACTS ENDOTOXIN-INDUCED INFLAMMATION AND COAGULATION AND AMELIORATES RENAL FIBRIN DEPOSITION IN A RAT MODEL OF ACUTE RENAL FAILURE

(2009) Subrina Jesmin et al.   SHOCK

Regulation of Arterial-Venous Differences in Tumor Necrosis Factor Responsiveness of Endothelial Cells by Anatomic Context

(2008) Meng Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

Bacterial infection-mediated mucosal signalling induces local renal ischaemia as a defence against sepsis

(2008) Keira Melican et al.   CELLULAR MICROBIOLOGY

Divergent roles of endothelial NF-κB in multiple organ injury and bacterial clearance in mouse models of sepsis

(2008) Xiaobing Ye et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunohistochemical detection of sphingosine-1-phosphate receptor 1 in vascular and lymphatic endothelial cells

(2008) Takashi Akiyama et al.   JOURNAL OF MOLECULAR HISTOLOGY

Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell–cell and cell–matrix contacts

(2008) Pipsa Saharinen et al.   NATURE CELL BIOLOGY