Mechanisms and Models of Kidney Tubular Necrosis and Nephron Loss

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Dimethyl fumarate induces ferroptosis and impairs NF-κB/STAT3 signaling in DLBCL

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TYRO3 induces anti–PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis

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DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer

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A mitochondrial gatekeeper that helps cells escape death by ferroptosis

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Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1

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Obesity-Dependent Adipokine Chemerin Suppresses Fatty Acid Oxidation to Confer Ferroptosis Resistance

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Novel porphyrazine-based photodynamic anti-cancer therapy induces immunogenic cell death

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Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity

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Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury

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A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis

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Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair

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Energy-stress-mediated AMPK activation inhibits ferroptosis

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DJ-1 suppresses ferroptosis through preserving the activity of S-adenosyl homocysteine hydrolase

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Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis

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Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis

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Necroptosis-based CRISPR knockout screen reveals Neuropilin-1 as a critical host factor for early stages of murine cytomegalovirus infection

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Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injury

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Plasticity of ether lipids promotes ferroptosis susceptibility and evasion

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Ferroptosis occurs through an osmotic mechanism and propagates independently of cell rupture

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Ferroptosis involves in renal tubular cell death in diabetic nephropathy

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Ferroptosis becomes immunogenic: implications for anticancer treatments

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ZBP1/DAI Drives RIPK3-Mediated Cell Death Induced by IFNs in the Absence of RIPK1

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Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity

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Drugs Repurposed as Antiferroptosis Agents Suppress Organ Damage, Including AKI, by Functioning as Lipid Peroxyl Radical Scavengers

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A powerful cell-protection system prevents cell death by ferroptosis

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FSP1 is a glutathione-independent ferroptosis suppressor

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The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

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K63-linked ubiquitination regulates RIPK1 kinase activity to prevent cell death during embryogenesis and inflammation

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Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway

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The TWEAK/Fn14 pathway is required for calcineurin inhibitor toxicity of the kidneys

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Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

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RGMb protects against acute kidney injury by inhibiting tubular cell necroptosis via an MLKL-dependent mechanism

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RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation

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TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation

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Phospholipid flippases enable precursor B cells to flee engulfment by macrophages

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Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection

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Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death

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Mouse cytomegalovirus M36 and M45 death suppressors cooperate to prevent inflammation resulting from antiviral programmed cell death pathways

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Necroptosis controls NET generation and mediates complement activation, endothelial damage, and autoimmune vasculitis

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Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis

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On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death

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RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus

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Novel Ferroptosis Inhibitors with Improved Potency and ADME Properties

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Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid–Induced AKI

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Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis

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Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

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ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

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Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth

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Actin is an evolutionarily-conserved damage-associated molecular pattern that signals tissue injury in Drosophila melanogaster

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Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death

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Structure of the Complex of F-Actin and DNGR-1, a C-Type Lectin Receptor Involved in Dendritic Cell Cross-Presentation of Dead Cell-Associated Antigens

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Suppression of RIP3-dependent Necroptosis by Human Cytomegalovirus

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Hepcidin Mitigates Renal Ischemia-Reperfusion Injury by Modulating Systemic Iron Homeostasis

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A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis

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Structure Guided Design of Potent and Selective Ponatinib-Based Hybrid Inhibitors for RIPK1

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PolyI:C-Induced, TLR3/RIP3-Dependent Necroptosis Backs Up Immune Effector-Mediated Tumor Elimination In Vivo

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RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis

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RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3

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RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis

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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

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Synchronized renal tubular cell death involves ferroptosis

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Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

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DAI/ZBP1/DLM-1 Complexes with RIP3 to Mediate Virus-Induced Programmed Necrosis that Is Targeted by Murine Cytomegalovirus vIRA

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