A compendium of kinetic modulatory profiles identifies ferroptosis regulators
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A compendium of kinetic modulatory profiles identifies ferroptosis regulators
Authors
Keywords
-
Journal
Nature Chemical Biology
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-03-09
DOI
10.1038/s41589-021-00751-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Transcription factors in ferroptotic cell death
- (2020) Chongshan Dai et al. CANCER GENE THERAPY
- Drug antagonism and single-agent dominance result from differences in death kinetics
- (2020) Ryan Richards et al. Nature Chemical Biology
- EO771, the first luminal B mammary cancer cell line from C57BL/6 mice
- (2020) Augustin Le Naour et al. Cancer Cell International
- Dietary Lipids Induce Ferroptosis in Caenorhabditis elegans and Human Cancer Cells
- (2020) Marcos A. Perez et al. DEVELOPMENTAL CELL
- Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers
- (2020) Mariluz Soula et al. Nature Chemical Biology
- Emerging Mechanisms and Disease Relevance of Ferroptosis
- (2020) Brent R. Stockwell et al. TRENDS IN CELL BIOLOGY
- A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity
- (2019) Jennifer Yinuo Cao et al. Cell Reports
- Bazedoxifene protects cerebral autoregulation after traumatic brain injury and attenuates impairments in blood–brain barrier damage: involvement of anti-inflammatory pathways by blocking MAPK signaling
- (2019) Yu-Long Lan et al. INFLAMMATION RESEARCH
- Drugs Repurposed as Antiferroptosis Agents Suppress Organ Damage, Including AKI, by Functioning as Lipid Peroxyl Radical Scavengers
- (2019) Eikan Mishima et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- The chemical basis of ferroptosis
- (2019) Marcus Conrad et al. Nature Chemical Biology
- Protective effects of the mechanistic target of rapamycin against excess iron and ferroptosis in cardiomyocytes
- (2018) Yuichi Baba et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice
- (2018) Xinxin Song et al. GASTROENTEROLOGY
- Discovery of Novel Dual Mechanism of Action Src Signaling and Tubulin Polymerization Inhibitors (KX2-391 and KX2-361)
- (2018) Michael P. Smolinski et al. JOURNAL OF MEDICINAL CHEMISTRY
- p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells
- (2018) Amy Tarangelo et al. Cell Reports
- Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis
- (2018) Ron Shah et al. ACS Central Science
- Inhibition of GCN2 sensitizes ASNS-low cancer cells to asparaginase by disrupting the amino acid response
- (2018) Akito Nakamura et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular mechanisms mediating the neuroprotective role of the selective estrogen receptor modulator, bazedoxifene, in acute ischemic stroke: A comparative study with 17β-estradiol
- (2017) Teresa Jover-Mengual et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent
- (2017) Marco Jost et al. MOLECULAR CELL
- mTOR Inhibition Restores Amino Acid Balance in Cells Dependent on Catabolism of Extracellular Protein
- (2017) Michel Nofal et al. MOLECULAR CELL
- Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
- (2017) Vasanthi S. Viswanathan et al. NATURE
- The Drug Repurposing Hub: a next-generation drug library and information resource
- (2017) Steven M Corsello et al. NATURE MEDICINE
- Deconvolution of Buparlisib’s mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention
- (2017) Thomas Bohnacker et al. Nature Communications
- Systematic Quantification of Population Cell Death Kinetics in Mammalian Cells
- (2017) Giovanni C. Forcina et al. Cell Systems
- Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity
- (2017) Frederick M. Tomlin et al. ACS Central Science
- On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death
- (2017) Omkar Zilka et al. ACS Central Science
- The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway
- (2016) Lynne Chantranupong et al. CELL
- Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis
- (2016) Kenichi Shimada et al. Nature Chemical Biology
- Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth
- (2016) Shira L Cramer et al. NATURE MEDICINE
- Crosstalk between cystine and glutathione is critical for the regulation of amino acid signaling pathways and ferroptosis
- (2016) Xinlei Yu et al. Scientific Reports
- A Continuous Visible Light Spectrophotometric Approach To Accurately Determine the Reactivity of Radical-Trapping Antioxidants
- (2015) Evan A. Haidasz et al. JOURNAL OF ORGANIC CHEMISTRY
- Glutaminolysis and Transferrin Regulate Ferroptosis
- (2015) Minghui Gao et al. MOLECULAR CELL
- Correlating chemical sensitivity and basal gene expression reveals mechanism of action
- (2015) Matthew G Rees et al. Nature Chemical Biology
- Optimized ferrozine-based assay for dissolved iron
- (2014) Thomas M. Jeitner ANALYTICAL BIOCHEMISTRY
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models
- (2014) Rachid Skouta et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
- (2014) Scott J Dixon et al. eLife
- Besting Vitamin E: Sidechain Substitution is Key to the Reactivity of Naphthyridinol Antioxidants in Lipid Bilayers
- (2013) Bo Li et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin
- (2013) S. A. Kang et al. SCIENCE
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- A unifying model for mTORC1-mediated regulation of mRNA translation
- (2012) Carson C. Thoreen et al. NATURE
- Modulatory profiling identifies mechanisms of small molecule-induced cell death
- (2011) A. J. Wolpaw et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation
- (2010) Jiangbin Ye et al. EMBO JOURNAL
- Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells
- (2008) Wan Seok Yang et al. CHEMISTRY & BIOLOGY
- Efficacy of Bazedoxifene in Reducing New Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis: Results From a 3-Year, Randomized, Placebo-, and Active-Controlled Clinical Trial*
- (2008) Stuart L Silverman et al. JOURNAL OF BONE AND MINERAL RESEARCH
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now