Actin is an evolutionarily-conserved damage-associated molecular pattern that signals tissue injury in Drosophila melanogaster

Cytokine Diedel and a viral homologue suppress the IMD pathway inDrosophila

(2016) Olivier Lamiable et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Remote Control of Intestinal Stem Cell Activity by Haemocytes in Drosophila

(2016) Sveta Chakrabarti et al.   PLoS Genetics

Innate Immune Pattern Recognition: A Cell Biological Perspective

(2015) Sky W. Brubaker et al.   Annual Review of Immunology

Draper/CED-1 Mediates an Ancient Damage Response to Control Inflammatory Blood Cell Migration In Vivo

(2015) Iwan Robert Evans et al.   CURRENT BIOLOGY

JAK/STAT signaling in Drosophila muscles controls the cellular immune response against parasitoid infection

(2015) H. Yang et al.   EMBO REPORTS

Macrophage-Derived upd3 Cytokine Causes Impaired Glucose Homeostasis and Reduced Lifespan in Drosophila Fed a Lipid-Rich Diet

(2015) Katie J. Woodcock et al.   IMMUNITY

Structure of the Complex of F-Actin and DNGR-1, a C-Type Lectin Receptor Involved in Dendritic Cell Cross-Presentation of Dead Cell-Associated Antigens

(2015) Pavel Hanč et al.   IMMUNITY

Sterile Inflammation inDrosophila

(2015) Zeeshan Shaukat et al.   MEDIATORS OF INFLAMMATION

Innate immunity in Alzheimer's disease

(2015) Michael T Heneka et al.   NATURE IMMUNOLOGY

Accumulation of differentiating intestinal stem cell progenies drives tumorigenesis

(2015) Zongzhao Zhai et al.   Nature Communications

The Epigenetic Regulator G9a Mediates Tolerance to RNA Virus Infection in Drosophila

(2015) Sarah H. Merkling et al.   PLoS Pathogens

Cytoplasmic Actin Is an Extracellular Insect Immune Factor which Is Secreted upon Immune Challenge and Mediates Phagocytosis and Direct Killing of Bacteria, and Is a Plasmodium Antagonist

(2015) Simone L. Sandiford et al.   PLoS Pathogens

Death following traumatic brain injury in Drosophila is associated with intestinal barrier dysfunction

(2015) Rebeccah J Katzenberger et al.   eLife

DAMPs from Cell Death to New Life

(2015) Emilie Vénéreau et al.   Frontiers in Immunology

Methods to study Drosophila immunity

(2014) Claudine Neyen et al.   METHODS

Src kinase function controls progenitor cell pools during regeneration and tumor onset in the Drosophila intestine

(2014) A Kohlmaier et al.   ONCOGENE

JAK/STAT Pathway inDrosophilaImmunity

(2014) H. Myllymäki et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Wound repair and regeneration: Mechanisms, signaling, and translation

(2014) S. A. Eming et al.   Science Translational Medicine

The Bacterial Effector VopL Organizes Actin into Filament-like Structures

(2013) Jacob A. Zahm et al.   CELL

Calcium Flashes Orchestrate the Wound Inflammatory Response through DUOX Activation and Hydrogen Peroxide Release

(2013) William Razzell et al.   CURRENT BIOLOGY

JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles

(2013) Anthony Mathelier et al.   NUCLEIC ACIDS RESEARCH

A Drosophila model of closed head traumatic brain injury

(2013) R. J. Katzenberger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immune anticipation of mating in Drosophila: Turandot M promotes immunity against sexually transmitted fungal infections

(2013) W. Zhong et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Adaptive immunity after cell death

(2013) Santiago Zelenay et al.   TRENDS IN IMMUNOLOGY

Clearing the Dead: Apoptotic Cell Sensing, Recognition, Engulfment, and Digestion

(2013) A. Hochreiter-Hufford et al.   Cold Spring Harbor Perspectives in Biology

Homeostatic Epithelial Renewal in the Gut Is Required for Dampening a Fatal Systemic Wound Response in Drosophila

(2013) Asuka Takeishi et al.   Cell Reports

Wolbachia Variants Induce Differential Protection to Viruses in Drosophila melanogaster: A Phenotypic and Phylogenomic Analysis

(2013) Ewa Chrostek et al.   PLoS Genetics

Drosophila Cytokine Unpaired 2 Regulates Physiological Homeostasis by Remotely Controlling Insulin Secretion

(2012) Akhila Rajan et al.   CELL

Evolution of Inflammatory Diseases

(2012) Daniel Okin et al.   CURRENT BIOLOGY

The UPD3 cytokine couples environmental challenge and intestinal stem cell division through modulation of JAK/STAT signaling in the stem cell microenvironment

(2012) Feng Zhou et al.   DEVELOPMENTAL BIOLOGY

Genetic evidence of a redox-dependent systemic wound response via Hayan Protease-Phenoloxidase system inDrosophila

(2012) Hyuck-Jin Nam et al.   EMBO JOURNAL

Biology and significance of the JAK/STAT signalling pathways

(2012) Hiu Kiu et al.   GROWTH FACTORS

F-Actin Is an Evolutionarily Conserved Damage-Associated Molecular Pattern Recognized by DNGR-1, a Receptor for Dead Cells

(2012) Susan Ahrens et al.   IMMUNITY

The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments

(2012) Jian-Guo Zhang et al.   IMMUNITY

Autocrine and paracrine unpaired signaling regulate intestinal stem cell maintenance and division

(2012) D. Osman et al.   JOURNAL OF CELL SCIENCE

The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice

(2012) Santiago Zelenay et al.   JOURNAL OF CLINICAL INVESTIGATION

The DC receptor DNGR-1 mediates cross-priming of CTLs during vaccinia virus infection in mice

(2012) Salvador Iborra et al.   JOURNAL OF CLINICAL INVESTIGATION

Broad RNA Interference-Mediated Antiviral Immunity and Virus-Specific Inducible Responses in Drosophila

(2012) C. Kemp et al.   JOURNAL OF IMMUNOLOGY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Methylmercury tolerance is associated with the humoral stress factor gene Turandot A

(2012) Cecon T. Mahapatra et al.   NEUROTOXICOLOGY AND TERATOLOGY

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Maintaining Tissue Homeostasis: Dynamic Control of Somatic Stem Cell Activity

(2011) Benoit Biteau et al.   Cell Stem Cell

Differential activities of the Drosophila JAK/STAT pathway ligands Upd, Upd2 and Upd3

(2011) Victoria M. Wright et al.   CELLULAR SIGNALLING

Lyn is a redox sensor that mediates leukocyte wound attraction in vivo

(2011) Sa Kan Yoo et al.   NATURE

Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation

(2011) Dmitri V. Krysko et al.   TRENDS IN IMMUNOLOGY

The Sterile Inflammatory Response

(2010) Kenneth L. Rock et al.   Annual Review of Immunology

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Inflammation 2010: New Adventures of an Old Flame

(2010) Ruslan Medzhitov   CELL

EGFR/Ras/MAPK Signaling Mediates Adult Midgut Epithelial Homeostasis and Regeneration in Drosophila

(2010) Huaqi Jiang et al.   Cell Stem Cell

Transcriptional targets of Drosophila JAK/STAT pathway signalling as effectors of haematopoietic tumour formation

(2010) Samira Bina et al.   EMBO REPORTS

Dual oxidase in mucosal immunity and host–microbe homeostasis

(2010) Yun Soo Bae et al.   TRENDS IN IMMUNOLOGY

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Cytokine/Jak/Stat Signaling Mediates Regeneration and Homeostasis in the Drosophila Midgut

(2009) Huaqi Jiang et al.   CELL

JAK/STAT signaling coordinates stem cell proliferation and multilineage differentiation in the Drosophila intestinal stem cell lineage

(2009) Katherine Beebe et al.   DEVELOPMENTAL BIOLOGY

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

(2009) Matthew J. Robinson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of a dendritic cell receptor that couples sensing of necrosis to immunity

(2009) David Sancho et al.   NATURE

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

(2009) Philipp Niethammer et al.   NATURE

Pscan: finding over-represented transcription factor binding site motifs in sequences from co-regulated or co-expressed genes

(2009) Federico Zambelli et al.   NUCLEIC ACIDS RESEARCH

Paracrine Unpaired Signaling through the JAK/STAT Pathway Controls Self-renewal and Lineage Differentiation of Drosophila Intestinal Stem Cells

(2009) G. Lin et al.   Journal of Molecular Cell Biology

The Inflammatory Response to Cell Death

(2008) Kenneth L. Rock et al.   Annual Review of Pathology-Mechanisms of Disease

An innate immune response of blood cells to tumors and tissue damage in Drosophila

(2008) J. C. Pastor-Pareja et al.   Disease Models & Mechanisms

Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling

(2008) Jennifer S. Ziegenfuss et al.   NATURE

Wolbachia and Virus Protection in Insects

(2008) L. M. Hedges et al.   SCIENCE

The Bacterial Symbiont Wolbachia Induces Resistance to RNA Viral Infections in Drosophila melanogaster

(2008) Luís Teixeira et al.   PLOS BIOLOGY