CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability
Authors
Keywords
CD8, T cells, CD36, lipid peroxidation, ferroptosis
Journal
Cell Metabolism
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-03-10
DOI
10.1016/j.cmet.2021.02.015
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Enhanced lipid accumulation and metabolism are required for the differentiation and activation of tumor-associated macrophages
- (2020) Pan Su et al. CANCER RESEARCH
- CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors
- (2020) Haiping Wang et al. NATURE IMMUNOLOGY
- Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
- (2019) Moshe Sade-Feldman et al. CELL
- Cholesterol Induces CD8+ T Cell Exhaustion in the Tumor Microenvironment
- (2019) Xingzhe Ma et al. Cell Metabolism
- CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy
- (2019) Weimin Wang et al. NATURE
- Cholesterol induces T cell exhaustion
- (2019) Xingzhe Ma et al. Aging-US
- Changes in Plasma Free Fatty Acids Associated with Type-2 Diabetes
- (2019) Amélie I. S. Sobczak et al. Nutrients
- The Role of Sirtuins in Antioxidant and Redox Signaling
- (2018) Chandra K. Singh et al. ANTIOXIDANTS & REDOX SIGNALING
- T Cell Dysfunction in Cancer
- (2018) Daniela S. Thommen et al. CANCER CELL
- The cellular metabolic landscape in the tumor milieu regulates the activity of myeloid infiltrates
- (2018) Eslam Mohamed et al. Cellular & Molecular Immunology
- Transfer of Cell-Surface Antigens by Scavenger Receptor CD36 Promotes Thymic Regulatory T Cell Receptor Repertoire Development and Allo-tolerance
- (2018) Justin S.A. Perry et al. IMMUNITY
- Cholesterol negatively regulates IL-9–producing CD8+T cell differentiation and antitumor activity
- (2018) Xingzhe Ma et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Global characterization of T cells in non-small-cell lung cancer by single-cell sequencing
- (2018) Xinyi Guo et al. NATURE MEDICINE
- Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins
- (2018) Maomao Zhang et al. Cancer Discovery
- Principles of adoptive T cell therapy in cancer
- (2018) Özcan Met et al. Seminars in Immunopathology
- Reversing T-cell Dysfunction and Exhaustion in Cancer
- (2016) H. M. Zarour CLINICAL CANCER RESEARCH
- Spontaneous onset and transplant models of the Vk*MYC mouse show immunological sequelae comparable to human multiple myeloma
- (2016) Rachel E. Cooke et al. Journal of Translational Medicine
- ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
- (2016) Sebastian Doll et al. Nature Chemical Biology
- Emerging concepts of T cell metabolism as a target of immunotherapy
- (2016) Chih-Hao Chang et al. NATURE IMMUNOLOGY
- Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
- (2016) Wan Seok Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabolic pathways in T cell activation and lineage differentiation
- (2016) Luís Almeida et al. SEMINARS IN IMMUNOLOGY
- Ferroptosis: Death by Lipid Peroxidation
- (2016) Wan Seok Yang et al. TRENDS IN CELL BIOLOGY
- TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis
- (2016) Daniel Zysset et al. Nature Communications
- T cell lipid peroxidation induces ferroptosis and prevents immunity to infection
- (2015) Mai Matsushita et al. JOURNAL OF EXPERIMENTAL MEDICINE
- T cell exclusion, immune privilege, and the tumor microenvironment
- (2015) J. A. Joyce et al. SCIENCE
- Structure-Function of CD36 and Importance of Fatty Acid Signal Transduction in Fat Metabolism
- (2014) Marta Yanina Pepino et al. Annual Review of Nutrition
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- Selection of an Antibody Library Identifies a Pathway to Induce Immunity by Targeting CD36 on Steady-State CD8 + Dendritic Cells
- (2014) E. Tagliani et al. JOURNAL OF IMMUNOLOGY
- PD-1 blockade induces responses by inhibiting adaptive immune resistance
- (2014) Paul C. Tumeh et al. NATURE
- Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
- (2014) Antonio Ayala et al. Oxidative Medicine and Cellular Longevity
- Innate and adaptive immune cells in the tumor microenvironment
- (2013) Thomas F Gajewski et al. NATURE IMMUNOLOGY
- Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling
- (2010) Eric Verdin et al. TRENDS IN BIOCHEMICAL SCIENCES
- Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study
- (2009) Jedd D Wolchok et al. LANCET ONCOLOGY
- CD36, a Scavenger Receptor Involved in Immunity, Metabolism, Angiogenesis, and Behavior
- (2009) R. L. Silverstein et al. Science Signaling
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search