Ferroptosis in Non-Small Cell Lung Cancer: Progression and Therapeutic Potential on It

Isoliquiritigenin Suppresses EMT-Induced Metastasis in Triple-Negative Breast Cancer through miR-200c/C-JUN/β-Catenin

(2021) Fu Peng et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Gut Microbiota in Tumor Microenvironment: A Critical Regulator in Cancer Initiation and Development as Potential Targets for Chinese Medicine

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Intracranial and extracranial efficacy of lorlatinib in patients with ALK-positive non-small-cell lung cancer previously treated with second-generation ALK TKIs

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Dysregulation of ferroptosis may involve in the development of non‐small‐cell lung cancer in Xuanwei area

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Non-coding RNAs regulation of macrophage polarization in cancer

(2021) Swati Mohapatra et al.   Molecular Cancer

Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS‐mitochondrial fission‐mitophagy axis

(2021) Ming Liu et al.   Molecular Oncology

Broadening horizons: the role of ferroptosis in cancer

(2021) Xin Chen et al.   Nature Reviews Clinical Oncology

Curcumin induces ferroptosis in non‐small‐cell lung cancer via activating autophagy

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Pemetrexed Plus Platinum With or Without Pembrolizumab in Patients With Previously Untreated Metastatic Nonsquamous NSCLC: Protocol-Specified Final Analysis From KEYNOTE-189

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Vitamin C induces ferroptosis in anaplastic thyroid cancer cells by ferritinophagy activation

(2021) Xiaowen Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

miR-324-3p reverses cisplatin resistance by inducing GPX4-mediated ferroptosis in lung adenocarcinoma cell line A549

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Construction of a prognostic model for non-small-cell lung cancer based on ferroptosis-related genes

(2021) Ke Han et al.   BIOSCIENCE REPORTS

Dimethyl fumarate induces ferroptosis and impairs NF-κB/STAT3 signaling in DLBCL

(2021) Anja Schmitt et al.   BLOOD

Long non-coding RNA NEAT1 regulates ferroptosis sensitivity in non-small-cell lung cancer

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KRAS secondary mutations that confer acquired resistance to KRAS G12C inhibitors, sotorasib and adagrasib, and overcoming strategies: insights from the in vitro experiments

(2021) Takamasa Koga et al.   Journal of Thoracic Oncology

Th17 cells contribute to combination MEK inhibitor and anti-PD-L1 therapy resistance in KRAS/p53 mutant lung cancers

(2021) David H. Peng et al.   Nature Communications

Identification of ferroptosis as a novel mechanism for antitumor activity of natural product derivative a2 in gastric cancer

(2021) Ying Liu et al.   Acta Pharmaceutica Sinica B

Local anesthetic levobupivacaine induces ferroptosis and inhibits progression by up-regulating p53 in non-small cell lung cancer

(2021) Minghua Meng et al.   Aging-US

Nivolumab with carboplatin, paclitaxel, and bevacizumab for first-line treatment of advanced nonsquamous non-small-cell lung cancer

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Inhibition of GPX4 or mTOR overcomes resistance to Lapatinib via promoting ferroptosis in NSCLC cells

(2021) Jiangwei Ni et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cisplatin synergizes with PRLX93936 to induce ferroptosis in non-small cell lung cancer cells

(2021) Zhigang Liang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular identification of an immunity- and Ferroptosis-related gene signature in non-small cell lung Cancer

(2021) Taisheng Liu et al.   BMC CANCER

MicroRNA-302a-3p induces ferroptosis of non-small cell lung cancer cells via targeting ferroportin

(2021) Dong Wei et al.   FREE RADICAL RESEARCH

Renal Clearable Ultrasmall Single-Crystal Fe Nanoparticles for Highly Selective and Effective Ferroptosis Therapy and Immunotherapy

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Acquired resistance to third-generation EGFR tyrosine kinase inhibitors in patients with de novo EGFRT790M-mutant non–small cell lung cancer

(2021) Ha-Ram Park et al.   Journal of Thoracic Oncology

Estrogen Promotes Resistance to Bevacizumab in Murine Models of NSCLC

(2021) Sonia A. Patel et al.   Journal of Thoracic Oncology

Exosomal miR-4443 promotes cisplatin resistance in non-small cell lung carcinoma by regulating FSP1 m6A modification-mediated ferroptosis

(2021) Zhiyu Song et al.   LIFE SCIENCES

Toward personalized treatment approaches for non-small-cell lung cancer

(2021) Meina Wang et al.   NATURE MEDICINE

Cell death in pancreatic cancer: from pathogenesis to therapy

(2021) Xin Chen et al.   Nature Reviews Gastroenterology & Hepatology

GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis

(2021) Daniel M. Kremer et al.   Nature Communications

Gene interfered-ferroptosis therapy for cancers

(2021) Jinliang Gao et al.   Nature Communications

Ferroptosis, a New Insight Into Acute Lung Injury

(2021) Xiaofang Yin et al.   Frontiers in Pharmacology

Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell lung cancer

(2021) Laurie Freire Boullosa et al.   Redox Biology

Non-enzymatic lipid peroxidation initiated by photodynamic therapy drives a distinct ferroptosis-like cell death pathway

(2021) Sufang Shui et al.   Redox Biology

Metformin in Combination With Chemoradiotherapy in Locally Advanced Non–Small Cell Lung Cancer

(2021) Theodoros Tsakiridis et al.   JAMA Oncology

Development and Validation of a Robust Ferroptosis-Related Prognostic Signature in Lung Adenocarcinoma

(2021) Anran Zhang et al.   Frontiers in Cell and Developmental Biology

Melatonin protects against PM2.5-induced lung injury by inhibiting ferroptosis of lung epithelial cells in a Nrf2-dependent manner

(2021) Fan Guohua et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Effect of curcumin on lung epithelial injury and ferroptosis induced by cigarette smoke

(2021) Xin Tang et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Environmental allergens house dust mite‑induced asthma is associated with ferroptosis in the lungs

(2021) Weifeng Tang et al.   Experimental and Therapeutic Medicine

The role of ferroptosis in lung cancer

(2021) Sikai Wu et al.   Biomarker Research

Long-Term Outcomes and Retreatment Among Patients With Previously Treated, Programmed Death-Ligand 1‒Positive, Advanced Non‒Small-Cell Lung Cancer in the KEYNOTE-010 Study

(2020) Roy S. Herbst et al.   JOURNAL OF CLINICAL ONCOLOGY

CAF secreted miR-522 suppresses ferroptosis and promotes acquired chemo-resistance in gastric cancer

(2020) Haiyang Zhang et al.   Molecular Cancer

Dissecting Programmed Cell Death with Small Molecules

(2020) Yingjie Bai et al.   ACCOUNTS OF CHEMICAL RESEARCH

LINC00173.v1 promotes angiogenesis and progression of lung squamous cell carcinoma by sponging miR-511-5p to regulate VEGFA expression

(2020) Jiarong Chen et al.   Molecular Cancer

Induction of programmed necrosis: A novel anti-cancer strategy for natural compounds

(2020) Jie Yu et al.   PHARMACOLOGY & THERAPEUTICS

(-)-Sativan Inhibits Tumor Development and Regulates miR-200c/PD-L1 in Triple Negative Breast Cancer Cells

(2020) Fu Peng et al.   Frontiers in Pharmacology

Isoliquiritigenin Derivative Regulates miR-374a/BAX Axis to Suppress Triple-Negative Breast Cancer Tumorigenesis and Development

(2020) Fu Peng et al.   Frontiers in Pharmacology

Circular RNA circSATB2 promotes progression of non-small cell lung cancer cells

(2020) Nan Zhang et al.   Molecular Cancer

Erastin triggers autophagic death of breast cancer cells by increasing intracellular iron levels

(2020) Mengxin Li et al.   Oncology Letters

Stereotactic Body Radiotherapy Versus Delayed Surgery for Early-stage Non-small-cell Lung Cancer

(2020) Nicholas R. Mayne et al.   ANNALS OF SURGERY

Cryptotanshinone strengthens the effect of gefitinib against non-small cell lung cancer through inhibiting transketolase

(2020) Lin Cao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Characterization of a novel HDAC/RXR/HtrA1 signaling axis as a novel target to overcome cisplatin resistance in human non-small cell lung cancer

(2020) Wenjing Wang et al.   Molecular Cancer

A decade of cell death studies: Breathing new life into necroptosis

(2020) Imran Khan et al.   PHARMACOLOGY & THERAPEUTICS

Ginkgetin derived from Ginkgo biloba leaves enhances the therapeutic effect of cisplatin via ferroptosis-mediated disruption of the Nrf2/HO-1 axis in EGFR wild-type non-small-cell lung cancer

(2020) Jian-Shu Lou et al.   PHYTOMEDICINE

MT1DP loaded by folate-modified liposomes sensitizes erastin-induced ferroptosis via regulating miR-365a-3p/NRF2 axis in non-small cell lung cancer cells

(2020) Chengcheng Gai et al.   Cell Death & Disease

NRF2 regulates the sensitivity of human NSCLC cells to cystine deprivation-induced ferroptosis via FOCAD-FAK signaling pathway

(2020) Pengfei Liu et al.   Redox Biology

Non-canonical Glutamate-Cysteine Ligase Activity Protects against Ferroptosis

(2020) Yun Pyo Kang et al.   Cell Metabolism

Erastin decreases radioresistance of NSCLC cells partially by inducing GPX4‑mediated ferroptosis

(2019) Xiaofen Pan et al.   Oncology Letters

RNA sequencing uncovers the key long non‑coding RNAs and potential molecular mechanism contributing to XAV939‑mediated inhibition of non‑small cell lung cancer

(2019) Haixiang Yu et al.   Oncology Letters

Ferroptosis: Yet Another Way to Die

(2019) Kemal Kazan et al.   TRENDS IN PLANT SCIENCE

Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA

(2019) Min Wang et al.   CELL DEATH AND DIFFERENTIATION

Liver stage malaria infection is controlled by host regulators of lipid peroxidation

(2019) Heather S. Kain et al.   CELL DEATH AND DIFFERENTIATION

Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis

(2019) Guo-Qing Chen et al.   CELL DEATH AND DIFFERENTIATION

Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial

(2019) Tony S K Mok et al.   LANCET

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

(2019) Weimin Wang et al.   NATURE

Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis

(2019) Masahiro Yoshida et al.   Nature Communications

Acetaminophen sensitizing erastin‐induced ferroptosis via modulation of Nrf2/heme oxygenase‐1 signaling pathway in non‐small‐cell lung cancer

(2019) Chengcheng Gai et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Erastin/sorafenib induces cisplatin‑resistant non‑small cell lung cancer cell ferroptosis through inhibition of the Nrf2/xCT pathway

(2019) Yu Li et al.   Oncology Letters

Curcumin potentiates the galbanic acid-induced anti-tumor effect in non-small cell lung cancer cells through inhibiting Akt/mTOR signaling pathway

(2019) Qian Zhang et al.   LIFE SCIENCES

Cisplatin-Based First-Line Treatment of Elderly Patients With Advanced Non–Small-Cell Lung Cancer: Joint Analysis of MILES-3 and MILES-4 Phase III Trials

(2018) Cesare Gridelli et al.   JOURNAL OF CLINICAL ONCOLOGY

Antitumor activity of curcumin by modulation of apoptosis and autophagy in human lung cancer A549 cells through inhibiting PI3K/Akt/mTOR pathway

(2018) Furong Liu et al.   ONCOLOGY REPORTS

Upregulation and activation of p53 by erastin‑induced reactive oxygen species contribute to cytotoxic and cytostatic effects in A549 lung cancer cells

(2018) Chaoli Huang et al.   ONCOLOGY REPORTS

Ferroptosis: A Novel Anti-tumor Action for Cisplatin

(2018) Jipeng Guo et al.   Cancer Research and Treatment

Identification of compound CA-5f as a novel late-stage autophagy inhibitor with potent anti-tumor effect against non-small cell lung cancer

(2018) Lu Zhang et al.   Autophagy

Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases

(2017) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial

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NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis

(2017) Samantha W. Alvarez et al.   NATURE

Oncogene-Selective Sensitivity to Synchronous Cell Death following Modulation of the Amino Acid Nutrient Cystine

(2017) Ioannis Poursaitidis et al.   Cell Reports

Ferroptosis is an autophagic cell death process

(2016) Minghui Gao et al.   CELL RESEARCH

Metallothionein-1G facilitates sorafenib resistance through inhibition of ferroptosis

(2016) Xiaofang Sun et al.   HEPATOLOGY

Switching Apoptosis to Ferroptosis: Metal–Organic Network for High-Efficiency Anticancer Therapy

(2016) Di-Wei Zheng et al.   NANO LETTERS

Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth

(2016) Sung Eun Kim et al.   Nature Nanotechnology

Ferroptosis as a p53-mediated activity during tumour suppression

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Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

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Is there a common upstream link for autophagic and apoptotic cell death in human high-grade gliomas?

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