miR-324-3p reverses cisplatin resistance by inducing GPX4-mediated ferroptosis in lung adenocarcinoma cell line A549

Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers

(2020) Mariluz Soula et al.   Nature Chemical Biology

miR-548e Sponged by ZFAS1 Regulates Metastasis and Cisplatin Resistance of OC by Targeting CXCR4 and let-7a/BCL-XL/S Signaling Axis

(2020) Jing Zhang et al.   Molecular Therapy-Nucleic Acids

Downregulation of microRNA-324-3p inhibits lung cancer by blocking the NCAM1-MAPK axis through ALX4

(2020) Tieniu Song et al.   CANCER GENE THERAPY

The Induction of Ferroptosis by Impairing STAT3/Nrf2/GPx4 Signaling Enhances the Sensitivity of Osteosarcoma Cells to Cisplatin

(2019) Qiang Liu et al.   CELL BIOLOGY INTERNATIONAL

Molecular basis and rationale for combining immune checkpoint inhibitors with chemotherapy in non-small cell lung cancer

(2019) Alessandro Leonetti et al.   DRUG RESISTANCE UPDATES

PLEK2 mediates metastasis and vascular invasion via the ubiquitin‐dependent degradation of SHIP2 in non‐small cell lung cancer

(2019) Dong‐ming Wu et al.   INTERNATIONAL JOURNAL OF CANCER

Inhibition of tumor propellant glutathione peroxidase 4 induces ferroptosis in cancer cells and enhances anticancer effect of cisplatin

(2019) Xuefei Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

(2019) Kirill Bersuker et al.   NATURE

GPx4, Lipid Peroxidation, and Cell Death: Discoveries, Rediscoveries, and Open Issues

(2018) Matilde Maiorino et al.   ANTIOXIDANTS & REDOX SIGNALING

Pseudolaric acid B triggers ferroptosis in glioma cells via activation of Nox4 and inhibition of xCT

(2018) Zongqi Wang et al.   CANCER LETTERS

Cisplatin-Based First-Line Treatment of Elderly Patients With Advanced Non–Small-Cell Lung Cancer: Joint Analysis of MILES-3 and MILES-4 Phase III Trials

(2018) Cesare Gridelli et al.   JOURNAL OF CLINICAL ONCOLOGY

Metformin Enhances Cisplatin-Induced Apoptosis and Prevents Resistance to Cisplatin in Co-mutated KRAS/LKB1 NSCLC

(2018) Massimo Moro et al.   Journal of Thoracic Oncology

Dual responsive micelles capable of modulating miRNA-34a to combat taxane resistance in prostate cancer

(2018) Feng Lin et al.   BIOMATERIALS

miR-324-3p promotes gastric cancer development by activating Smad4-mediated Wnt/beta-catenin signaling pathway

(2017) Guang-Li Sun et al.   JOURNAL OF GASTROENTEROLOGY

The expression of microRNA-324-3p as a tumor suppressor in nasopharyngeal carcinoma and its clinical significance

(2017) Han-qun Zhang et al.   OncoTargets and Therapy

SMARCA4/BRG1 Is a Novel Prognostic Biomarker Predictive of Cisplatin-Based Chemotherapy Outcomes in Resected Non-Small Cell Lung Cancer

(2015) E. H. Bell et al.   CLINICAL CANCER RESEARCH

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Reduced Expression of miRNA-27a Modulates Cisplatin Resistance in Bladder Cancer by Targeting the Cystine/Glutamate Exchanger SLC7A11

(2014) R. M. Drayton et al.   CLINICAL CANCER RESEARCH

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL