Crosstalk between macrophages and natural killer cells in the tumor microenvironment

IL-12 Family Cytokines in Cancer and Immunotherapy

(2021) Bhalchandra Mirlekar et al.   Cancers

Aryl Hydrocarbon Receptor Signaling Controls CD155 Expression on Macrophages and Mediates Tumor Immunosuppression

(2021) Zachary P. McKay et al.   JOURNAL OF IMMUNOLOGY

IL-10 Enhances Human Natural Killer Cell Effector Functions via Metabolic Reprogramming Regulated by mTORC1 Signaling

(2021) Zixi Wang et al.   Frontiers in Immunology

Short-term IL-15 priming leaves a long-lasting signalling imprint in mouse NK cells independently of a metabolic switch

(2021) Thuy T Luu et al.   Life Science Alliance

Metabolic changes of Interleukin-12/15/18-stimulated human NK cells

(2021) Iñigo Terrén et al.   Scientific Reports

NKG2D-CAR-transduced natural killer cells efficiently target multiple myeloma

(2021) Alejandra Leivas et al.   Blood Cancer Journal

A Fusion Protein Complex that Combines IL-12, IL-15, and IL-18 Signaling to Induce Memory-Like NK Cells for Cancer Immunotherapy

(2021) Michelle K. Becker-Hapak et al.   Cancer Immunology Research

Defects in Macrophage Reprogramming in Cancer Therapy: The Negative Impact of PD-L1/PD-1

(2021) Hao Cai et al.   Frontiers in Immunology

Top 10 Challenges in Cancer Immunotherapy

(2020) Priti S. Hegde et al.   IMMUNITY

Serum sHLA-G: Significant diagnostic biomarker with respect to therapy and immunosuppressive mediators in Head and Neck Squamous Cell Carcinoma

(2020) Vertica Agnihotri et al.   Scientific Reports

Tumor-Associated Macrophages: Recent Insights and Therapies

(2020) Jiawei Zhou et al.   Frontiers in Oncology

IL-12 regulates the expansion, phenotype, and function of murine NK cells activated by IL-15 and IL-18

(2020) Naoto Oka et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Human chimeric antigen receptor macrophages for cancer immunotherapy

(2020) Michael Klichinsky et al.   NATURE BIOTECHNOLOGY

CD226hiCD8+ T Cells Are a Prerequisite for Anti-TIGIT Immunotherapy

(2020) Hyung-seung Jin et al.   Cancer Immunology Research

IL15 Stimulation with TIGIT Blockade Reverses CD155-mediated NK-Cell Dysfunction in Melanoma

(2020) Joe-Marc Chauvin et al.   CLINICAL CANCER RESEARCH

Natural killer cells in cancer biology and therapy

(2020) Song-Yang Wu et al.   Molecular Cancer

Exploring the NK cell platform for cancer immunotherapy

(2020) Jacob A. Myers et al.   Nature Reviews Clinical Oncology

Roles of IFN-γ in tumor progression and regression: a review

(2020) Dragica Jorgovanovic et al.   Biomarker Research

Pharmacological activation of LXR alters the expression profile of tumor-associated macrophages and the abundance of regulatory T cells in the tumor microenvironment

(2020) José M. Carbó et al.   CANCER RESEARCH

Immune Checkpoint Inhibitors: Anti-NKG2A Antibodies on Board

(2019) Maria Cristina Mingari et al.   TRENDS IN IMMUNOLOGY

Interaction between nectin-1 and the human natural killer cell receptor CD96

(2019) Veronica M. Holmes et al.   PLoS One

The role of cytokines in the regulation of NK cells in the tumor environment

(2019) Gordana M. Konjević et al.   CYTOKINE

Shared and Distinct Functions of Type I and Type III Interferons

(2019) Helen M. Lazear et al.   IMMUNITY

Transforming Growth Factor-β Signaling in Immunity and Cancer

(2019) Eduard Batlle et al.   IMMUNITY

Targeting Tumor-Associated Macrophages in Cancer

(2019) Paulina Pathria et al.   TRENDS IN IMMUNOLOGY

Generation of monocyte-derived tumor-associated macrophages using tumor-conditioned media provides a novel method to study tumor-associated macrophages in vitro

(2019) Brooke Benner et al.   Journal for ImmunoTherapy of Cancer

The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell–mediated resistance to metastasis

(2019) Irene Mattiola et al.   NATURE IMMUNOLOGY

Immunomodulatory TGF-β Signaling in Hepatocellular Carcinoma

(2019) Jian Chen et al.   TRENDS IN MOLECULAR MEDICINE

IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells

(2019) Yeon Ho Choi et al.   Journal for ImmunoTherapy of Cancer

DNAM-1 and the TIGIT/PVRIG/TACTILE Axis: Novel Immune Checkpoints for Natural Killer Cell-Based Cancer Immunotherapy

(2019) Beatriz Sanchez-Correa et al.   Cancers

Human TIGIT on porcine aortic endothelial cells suppresses xenogeneic macrophage-mediated cytotoxicity

(2019) Yuki Noguchi et al.   IMMUNOBIOLOGY

NK Cell Dysfunction and Checkpoint Immunotherapy

(2019) Jiacheng Bi et al.   Frontiers in Immunology

Natural killer T cell activation increases iNOS+CD206- M1 macrophage and controls the growth of solid tumor

(2019) Sourav Paul et al.   Journal for ImmunoTherapy of Cancer

Interferon target-gene expression and epigenomic signatures in health and disease

(2019) Franck J. Barrat et al.   NATURE IMMUNOLOGY

JAK/STAT Cytokine Signaling at the Crossroad of NK Cell Development and Maturation

(2019) Dagmar Gotthardt et al.   Frontiers in Immunology

Monalizumab: inhibiting the novel immune checkpoint NKG2A

(2019) Thorbald van Hall et al.   Journal for ImmunoTherapy of Cancer

TIGIT as an emerging immune checkpoint

(2019) H. Harjunpää et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Harnessing tumor-associated macrophages as aids for cancer immunotherapy

(2019) Xiaolei Li et al.   Molecular Cancer

Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL

(2018) Frank Vari et al.   BLOOD

Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity

(2018) Ye Li et al.   Cell Stem Cell

Effect of IL-18 on the Expansion and Phenotype of Human Natural Killer Cells: Application to Cancer Immunotherapy

(2018) Hiroaki Senju et al.   International Journal of Biological Sciences

CD155 loss enhances tumor suppression via combined host and tumor-intrinsic mechanisms

(2018) Xian-Yang Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy

(2018) Rajani Ravi et al.   Nature Communications

Tumor-derived CSF-1 induces the NKG2D ligand RAE-1δ on tumor-infiltrating macrophages

(2018) Thornton W Thompson et al.   eLife

M7824, a novel bifunctional anti-PD-L1/TGFβ Trap fusion protein, promotes anti-tumor efficacy as monotherapy and in combination with vaccine

(2018) Karin M. Knudson et al.   OncoImmunology

Unleashing endogenous TNF-alpha as a cancer immunotherapeutic

(2018) Steven F. Josephs et al.   Journal of Translational Medicine

The yin-yang of the interaction between myelomonocytic cells and NK cells

(2018) Martina Molgora et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

IL-23 production of liver inflammatory macrophages to damaged hepatocytes promotes hepatocellular carcinoma development after chronic hepatitis B virus infection

(2018) Mengya Zang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells

(2018) Pascale André et al.   CELL

CD83 + CCR7 + NK cells induced by interleukin 18 by dendritic cells promote experimental autoimmune uveitis

(2018) Qiang Fu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

IL-15 is a component of the inflammatory milieu in the tumor microenvironment promoting antitumor responses

(2018) Rosa M. Santana Carrero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Immunology of Complement Receptors 3 and 4

(2018) Thomas Vorup-Jensen et al.   Frontiers in Immunology

Both Type I and Type II Interferons Can Activate Antitumor M1 Macrophages When Combined With TLR Stimulation

(2018) Elisabeth Müller et al.   Frontiers in Immunology

TGFβ Imprinting During Activation Promotes Natural Killer Cell Cytokine Hypersecretion

(2018) Jennifer Foltz et al.   Cancers

Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF

(2017) Kyuho Kang et al.   IMMUNITY

Tricking the balance: NK cells in anti-cancer immunity

(2017) Jens Pahl et al.   IMMUNOBIOLOGY

PD-L1 induced by IFN-γ from tumor-associated macrophages via the JAK/STAT3 and PI3K/AKT signaling pathways promoted progression of lung cancer

(2017) Xiaohui Zhang et al.   International Journal of Clinical Oncology

LFA-1 Activation in NK Cells and Their Subsets: Influence of Receptors, Maturation, and Cytokine Stimulation

(2017) Doris Urlaub et al.   JOURNAL OF IMMUNOLOGY

Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-β and Engagement of CD85j

(2017) Sol Y. Nuñez et al.   JOURNAL OF IMMUNOLOGY

Dual Roles of IL-27 in Cancer Biology and Immunotherapy

(2017) Marina Fabbi et al.   MEDIATORS OF INFLAMMATION

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages

(2017) W. K. Eddie Ip et al.   SCIENCE

CD155 expression and its correlation with clinicopathologic characteristics, angiogenesis, and prognosis in human cholangiocarcinoma

(2017) Da-Wei Huang et al.   OncoTargets and Therapy

Primary Tumors Limit Metastasis Formation through Induction of IL15-Mediated Cross-Talk between Patrolling Monocytes and NK Cells

(2017) Hiroshi Kubo et al.   Cancer Immunology Research

Tumor-Associated Monocytes/Macrophages Impair NK-Cell Function via TGFβ1 in Human Gastric Cancer

(2017) Liu-sheng Peng et al.   Cancer Immunology Research

Interferon Gamma Induces Changes in Natural Killer (NK) Cell Ligand Expression and Alters NK Cell-Mediated Lysis of Pediatric Cancer Cell Lines

(2017) Arianexys Aquino-López et al.   Frontiers in Immunology

Regulation of NK Cell Activation and Effector Functions by the IL-12 Family of Cytokines: The Case of IL-27

(2017) Norberto Walter Zwirner et al.   Frontiers in Immunology

Toll-Like Receptor Ligands and Interferon-γ Synergize for Induction of Antitumor M1 Macrophages

(2017) Elisabeth Müller et al.   Frontiers in Immunology

Soluble NKG2D ligands are biomarkers associated with the clinical outcome to immune checkpoint blockade therapy of metastatic melanoma patients

(2017) Cristina Maccalli et al.   OncoImmunology

Regulation of mTOR, Metabolic Fitness, and Effector Functions by Cytokines in Natural Killer Cells

(2017) Sébastien Viel et al.   Cancers

An IL-27/Stat3 axis induces expression of programmed cell death 1 ligands (PD-L1/2) on infiltrating macrophages in lymphoma

(2016) Hasita Horlad et al.   CANCER SCIENCE

Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation

(2016) Ana C. Anderson et al.   IMMUNITY

Elevated interleukin-27 levels in human neonatal macrophages regulate indoleamine dioxygenase in a STAT-1 and STAT-3-dependent manner

(2016) Joo-Yong Jung et al.   IMMUNOLOGY

M2-polarized and tumor-associated macrophages alter NK cell phenotype and function in a contact-dependent manner

(2016) Tamara Krneta et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Tim-3: Expression on immune cells and roles at the maternal-fetal interface

(2016) Xiao-Hui Hu et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

PI3Kγ is a molecular switch that controls immune suppression

(2016) Megan M. Kaneda et al.   NATURE

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

(2016) Sébastien Viel et al.   Science Signaling

IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance

(2016) David H. Munn et al.   TRENDS IN IMMUNOLOGY

TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype

(2016) Fan Zhang et al.   Oncotarget

Modulation of natural killer cell functions by interactions between 2B4 and CD48 incisand intrans

(2016) Maren Claus et al.   Open Biology

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

(2016) Sébastien Viel et al.   Science Signaling

Reprogramming the lung microenvironment by inhaled immunotherapy fosters immune destruction of tumor

(2016) Valentino Le Noci et al.   OncoImmunology

Autocrine IL-10 functions as a rheostat for M1 macrophage glycolytic commitment by tuning nitric oxide production

(2016) Walter A. Baseler et al.   Redox Biology

The breast tumor microenvironment alters the phenotype and function of natural killer cells

(2015) Tamara Krneta et al.   Cellular & Molecular Immunology

Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways

(2015) Irene Mattiola et al.   JOURNAL OF IMMUNOLOGY

IFN-γ Priming of Macrophages Represses a Part of the Inflammatory Program and Attenuates Neutrophil Recruitment

(2015) Marten A. Hoeksema et al.   JOURNAL OF IMMUNOLOGY

Dectin-1 Activation by a Natural Product β-Glucan Converts Immunosuppressive Macrophages into an M1-like Phenotype

(2015) Min Liu et al.   JOURNAL OF IMMUNOLOGY

Characterization of an IL-12 p40/p35 Truncated Fusion Protein That Can Inhibit the Action of IL-12

(2015) Denise Skrombolas et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Targeting the TGFβ pathway for cancer therapy

(2015) Cindy Neuzillet et al.   PHARMACOLOGY & THERAPEUTICS

A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection

(2015) W. Deng et al.   SCIENCE

ICAM-1 suppresses tumor metastasis by inhibiting macrophage M2 polarization through blockade of efferocytosis

(2015) M Yang et al.   Cell Death & Disease

IL-27 induces the expression of IDO and PD-L1 in human cancer cells

(2015) Grazia Carbotti et al.   Oncotarget

DNAM-1 Expression Marks an Alternative Program of NK Cell Maturation

(2015) Ludovic Martinet et al.   Cell Reports

TNF Counterbalances the Emergence of M2 Tumor Macrophages

(2015) Franz Kratochvill et al.   Cell Reports

Cancer-targeted IL-12 controls human rhabdomyosarcoma by senescence induction and myogenic differentiation

(2015) Karin Schilbach et al.   OncoImmunology

Favorable Alteration of Tumor Microenvironment by Immunomodulatory Cytokines for Efficient T-Cell Therapy in Solid Tumors

(2015) Siri Tähtinen et al.   PLoS One

mTOR inhibition: A promising strategy for stabilization of atherosclerotic plaques

(2014) Wim Martinet et al.   ATHEROSCLEROSIS

Fatty Acid-Binding Protein E-FABP Restricts Tumor Growth by Promoting IFN-  Responses in Tumor-Associated Macrophages

(2014) Y. Zhang et al.   CANCER RESEARCH

The role of indoleamine 2,3-dioxygenase (IDO) in immune tolerance: Focus on macrophage polarization of THP-1 cells

(2014) Xian-Feng Wang et al.   CELLULAR IMMUNOLOGY

IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness

(2014) Andrea Ziblat et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

In situ proliferation contributes to accumulation of tumor-associated macrophages in spontaneous mammary tumors

(2014) Piotr Tymoszuk et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TLR activation of tumor-associated macrophages from ovarian cancer patients triggers cytolytic activity of NK cells

(2014) Francesca Bellora et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IFN-λ-mediated IL-12 production in macrophages induces IFN-γ production in human NK cells

(2014) Rik A. de Groen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interferon gamma induced by resveratrol analog, HS-1793, reverses the properties of tumor associated macrophages

(2014) Soo Kyung Jeong et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

T-cell Immunoglobulin and ITIM Domain (TIGIT) Receptor/Poliovirus Receptor (PVR) Ligand Engagement Suppresses Interferon-γ Production of Natural Killer Cells via β-Arrestin 2-mediated Negative Signaling

(2014) Man Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: Priming of NK Cells by IL-18

(2014) J. Chaix et al.   JOURNAL OF IMMUNOLOGY

INAM Plays a Critical Role in IFN-γ Production by NK Cells Interacting with Polyinosinic-Polycytidylic Acid–Stimulated Accessory Cells

(2014) Jun Kasamatsu et al.   JOURNAL OF IMMUNOLOGY

IFN-γ Primes Macrophage Activation by Increasing Phosphatase and Tensin Homolog via Downregulation of miR-3473b

(2014) Cong Wu et al.   JOURNAL OF IMMUNOLOGY

Immune evasion mediated by tumor-derived lactate dehydrogenase induction of NKG2D ligands on myeloid cells in glioblastoma patients

(2014) C. A. Crane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Engineering of Hematopoiesis for Targeted IFN-  Delivery Inhibits Breast Cancer Progression

(2014) G. Escobar et al.   Science Translational Medicine

Homotypic NK cell-to-cell communication controls cytokine responsiveness of innate immune NK cells

(2014) Tae-Jin Kim et al.   Scientific Reports

Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses

(2014) Shiho Chiba et al.   eLife

IL-27 Driven Upregulation of Surface HLA-E Expression on Monocytes Inhibits IFN-γRelease by Autologous NK Cells

(2014) Fabio Morandi et al.   Journal of Immunology Research

Regulation of Ligands for the NKG2D Activating Receptor

(2013) David H. Raulet et al.   Annual Review of Immunology

Angiogenic capacity of M1- and M2-polarized macrophages is determined by the levels of TIMP-1 complexed with their secreted proMMP-9

(2013) E. Zajac et al.   BLOOD

Intercellular adhesion molecule-1 (ICAM-1) expression correlates with oral cancer progression and induces macrophage/cancer cell adhesion

(2013) Yu Usami et al.   INTERNATIONAL JOURNAL OF CANCER

Increased Th17 Cells in the Tumor Microenvironment Is Mediated by IL-23 via Tumor-Secreted Prostaglandin E2

(2013) X. Qian et al.   JOURNAL OF IMMUNOLOGY

Soluble Tumor Necrosis Factor Receptors Shed by Breast Tumor Cells Inhibit Macrophage Chemotaxis

(2013) Stephen Lee Rego et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

HLA-dependent tumour development: a role for tumour associate macrophages?

(2013) Maddalena Marchesi et al.   Journal of Translational Medicine

HLA-G expression in acute lymphoblastic leukemia: a significant prognostic tumor biomarker

(2013) Noura Alkhouly et al.   MEDICAL ONCOLOGY

A T-bet gradient controls the fate and function of CCR6−RORγt+ innate lymphoid cells

(2013) Christoph S. N. Klose et al.   NATURE

Toll-Like Receptor Ligands Induce Expression of the Costimulatory Molecule CD155 on Antigen-Presenting Cells

(2013) Neha Kamran et al.   PLoS One

Cyclooxygenase-2 Inhibition Blocks M2 Macrophage Differentiation and Suppresses Metastasis in Murine Breast Cancer Model

(2013) Yi-Rang Na et al.   PLoS One

Induction of TGF-β1 Synthesis by Macrophages in Response to Apoptotic Cells Requires Activation of the Scavenger Receptor CD36

(2013) Weipeng Xiong et al.   PLoS One

Expression of IL-27 by Tumor Cells in InvasCutaneous and Metastatic Melanomas

(2013) Julie Gonin et al.   PLoS One

Recruitment of Grb2 and SHIP1 by the ITT-like motif of TIGIT suppresses granule polarization and cytotoxicity of NK cells

(2012) S Liu et al.   CELL DEATH AND DIFFERENTIATION

M-CSF induces the expression of a membrane-bound form of IL-18 in a subset of human monocytes differentiating in vitro toward macrophages

(2012) Francesca Bellora et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Monocyte/macrophage-elicited natural killer cell dysfunction in hepatocellular carcinoma is mediated by CD48/2B4 interactions

(2012) Yan Wu et al.   HEPATOLOGY

IL-12 family cytokines: immunological playmakers

(2012) Dario A A Vignali et al.   NATURE IMMUNOLOGY

Macrophages Help NK Cells to Attack Tumor Cells by Stimulatory NKG2D Ligand but Protect Themselves from NK Killing by Inhibitory Ligand Qa-1

(2012) Zhixia Zhou et al.   PLoS One

The Inflammatory Microenvironment in Hepatocellular Carcinoma: A Pivotal Role for Tumor-Associated Macrophages

(2012) Daria Capece et al.   Biomed Research International

A model for cancer-suppressive inflammation

(2012) Ole Audun Werner Haabeth et al.   OncoImmunology

Complex regulation of human NKG2D-DAP10 cell surface expression: opposing roles of the  c cytokines and TGF- 1

(2011) Y. P. Park et al.   BLOOD

Direct Effects of Type I Interferons on Cells of the Immune System

(2011) S. Hervas-Stubbs et al.   CLINICAL CANCER RESEARCH

Cell Surface Signaling Molecules in the Control of Immune Responses: A Tide Model

(2011) Yuwen Zhu et al.   IMMUNITY

Interleukin-23: as a drug target for autoimmune inflammatory diseases

(2011) Chunlei Tang et al.   IMMUNOLOGY

Decreased expression of DNAM-1 on NK cells from acute myeloid leukemia patients

(2011) Beatriz Sanchez-Correa et al.   IMMUNOLOGY AND CELL BIOLOGY

2B4 Engagement Mediates Rapid LFA-1 and Actin-Dependent NK Cell Adhesion to Tumor Cells as Measured by Single Cell Force Spectroscopy

(2011) S. C. Hoffmann et al.   JOURNAL OF IMMUNOLOGY

IL-15-induced IL-10 increases the cytolytic activity of human natural killer cells

(2011) Ju Yeong Park et al.   MOLECULES AND CELLS

IL-27 Imparts Immunoregulatory Function to Human NK Cell Subsets

(2011) Alice Laroni et al.   PLoS One

Orally Administered Particulate  -Glucan Modulates Tumor-Capturing Dendritic Cells and Improves Antitumor T-Cell Responses in Cancer

(2010) B. Li et al.   CLINICAL CANCER RESEARCH

Tumor cells of non-hematopoietic and hematopoietic origins express activation-induced C-type lectin, the ligand for killer cell lectin-like receptor F1

(2010) A. Akatsuka et al.   INTERNATIONAL IMMUNOLOGY

Natural Killer Cell Cytotoxicity and Immunosuppressive Cytokines (IL-10, TGF-β1) in Patients with Gastric Cancer

(2010) Andrzej Szkaradkiewicz et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Identification of a polyI:C-inducible membrane protein that participates in dendritic cell–mediated natural killer cell activation

(2010) Takashi Ebihara et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Multiple Mechanisms Downstream of TLR-4 Stimulation Allow Expression of NKG2D Ligands To Facilitate Macrophage/NK Cell Crosstalk

(2010) P. Eissmann et al.   JOURNAL OF IMMUNOLOGY

Production of immune-modulatory nonclassical molecules HLA-G and HLA-E by tumor infiltrating ameboid microglia/macrophages in glioblastomas: A role in innate immunity?

(2010) Leos Kren et al.   JOURNAL OF NEUROIMMUNOLOGY

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

The interaction of human natural killer cells with either unpolarized or polarized macrophages results in different functional outcomes

(2010) F. Bellora et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-23 suppresses innate immune response independently of IL-17A during carcinogenesis and metastasis

(2010) M. W. L. Teng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transmembrane TNF- : structure, function and interaction with anti-TNF agents

(2010) T. Horiuchi et al.   RHEUMATOLOGY

Tumor necrosis factor-α enhances IL-15-induced natural killer cell differentiation

(2009) Jiwon Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors

(2009) Y. T. Bryceson et al.   BLOOD

Type I interferons inhibit the generation of tumor-associated macrophages

(2009) Lance U’Ren et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The effects of β-glucan on human immune and cancer cells

(2009) Godfrey Chan et al.   Journal of Hematology & Oncology

A phase I trial of paclitaxel and trastuzumab in combination with interleukin-12 in patients with HER2/neu-expressing malignancies

(2009) T. S. Bekaii-Saab et al.   MOLECULAR CANCER THERAPEUTICS

IL-1, IL-18, and IL-33 families of cytokines

(2008) William P. Arend et al.   IMMUNOLOGICAL REVIEWS

Functions of natural killer cells

(2008) Eric Vivier et al.   NATURE IMMUNOLOGY