TGFβ Imprinting During Activation Promotes Natural Killer Cell Cytokine Hypersecretion

An IL-15 superagonist/IL-15Rα fusion complex protects and rescues NK cell-cytotoxic function from TGF-β1-mediated immunosuppression

(2018) Rika Fujii et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Single Degranulations in NK Cells Can Mediate Target Cell Killing

(2018) Lavesh A. Gwalani et al.   JOURNAL OF IMMUNOLOGY

Adaptive NK Cells Resist Regulatory T-cell Suppression Driven by IL37

(2018) Dhifaf Sarhan et al.   Cancer Immunology Research

TGF-β in T Cell Biology: Implications for Cancer Immunotherapy

(2018) Amina Dahmani et al.   Cancers

CD56bright NK cells exhibit potent antitumor responses following IL-15 priming

(2017) Julia A. Wagner, Maximillian Rosario, Rizwan Romee, Melissa M. Berrien-Elliott, Stephanie E. Schneider, Jeffrey W. Leong, Ryan P. Sullivan, Brea A. Jewell, Michelle Becker-Hapak, Timothy Schappe, Sara Abdel-Latif, Aaron R. Ireland, Devika Jaishankar, Justin A. King, Ravi Vij, Dennis Clement, Jodie Goodridge, Karl-Johan Malmberg, Hing C. Wong, Todd A. Fehniger   JOURNAL OF CLINICAL INVESTIGATION

Smad3 promotes cancer progression by inhibiting E4BP4-mediated NK cell development

(2017) Patrick Ming-Kuen Tang et al.   Nature Communications

TGFβR1 Blockade with Galunisertib (LY2157299) Enhances Anti-Neuroblastoma Activity of the Anti-GD2 Antibody Dinutuximab (ch14.18) with Natural Killer Cells

(2016) Hung C. Tran et al.   CLINICAL CANCER RESEARCH

Transforming Growth Factor-β Signaling Guides the Differentiation of Innate Lymphoid Cells in Salivary Glands

(2016) Victor S. Cortez et al.   IMMUNITY

Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia

(2016) Rizwan Romee et al.   Science Translational Medicine

ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

(2015) Tauno Metsalu et al.   NUCLEIC ACIDS RESEARCH

Transcription of the activating receptor NKG2D in natural killer cells is regulated by STAT3 tyrosine phosphorylation

(2014) S. Zhu et al.   BLOOD

CREB, ATF, and AP-1 Transcription Factors Regulate IFN-  Secretion by Human T Cells in Response to Mycobacterial Antigen

(2014) B. Samten et al.   JOURNAL OF IMMUNOLOGY

TGF-  Utilizes SMAD3 to Inhibit CD16-Mediated IFN-  Production and Antibody-Dependent Cellular Cytotoxicity in Human NK Cells

(2014) R. Trotta et al.   JOURNAL OF IMMUNOLOGY

TGF- -inducible microRNA-183 silences tumor-associated natural killer cells

(2014) S. S. Donatelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lenalidomide overcomes suppression of human natural killer cell anti-tumor functions by neuroblastoma microenvironment-associated IL-6 and TGFβ1

(2013) Yibing Xu et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

IL-2–dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells

(2013) Georg Gasteiger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

Membrane-Bound IL-21 Promotes Sustained Ex Vivo Proliferation of Human Natural Killer Cells

(2012) Cecele J. Denman et al.   PLoS One

Complex regulation of human NKG2D-DAP10 cell surface expression: opposing roles of the  c cytokines and TGF- 1

(2011) Y. P. Park et al.   BLOOD

IFN-γ enhances HOS and U2OS cell lines susceptibility to γδ T cell-mediated killing through the Fas/Fas ligand pathway

(2011) Zhaoxu Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Natural killer cell-produced IFN-γ and TNF-α induce target cell cytolysis through up-regulation of ICAM-1

(2011) Ruipeng Wang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human Tumour Immune Evasion via TGF-β Blocks NK Cell Activation but Not Survival Allowing Therapeutic Restoration of Anti-Tumour Activity

(2011) Erica B. Wilson et al.   PLoS One

Expansion, Purification, and Functional Assessment of Human Peripheral Blood NK Cells

(2011) Srinivas S. Somanchi et al.   Jove-Journal of Visualized Experiments

TGF-β affects development and differentiation of human natural killer cell subsets

(2010) David S. J. Allan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Activating and inhibitory receptors of natural killer cells

(2010) Hollie J Pegram et al.   IMMUNOLOGY AND CELL BIOLOGY

CD56brightnatural killer (NK) cells: an important NK cell subset

(2008) Aurélie Poli et al.   IMMUNOLOGY