IL-15 is a component of the inflammatory milieu in the tumor microenvironment promoting antitumor responses
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
IL-15 is a component of the inflammatory milieu in the tumor microenvironment promoting antitumor responses
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 116, Issue 2, Pages 599-608
Publisher
Proceedings of the National Academy of Sciences
Online
2018-12-27
DOI
10.1073/pnas.1814642116
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Inflammatory Signals Regulate IL-15 in Response to Lymphodepletion
- (2016) Scott M. Anthony et al. JOURNAL OF IMMUNOLOGY
- Characterization of PD-L1 Expression and Associated T-cell Infiltrates in Metastatic Melanoma Samples from Variable Anatomic Sites
- (2015) H. M. Kluger et al. CLINICAL CANCER RESEARCH
- Inflammatory IL-15 is required for optimal memory T cell responses
- (2015) Martin J. Richer et al. JOURNAL OF CLINICAL INVESTIGATION
- STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity
- (2015) Olivier Demaria et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity
- (2015) Leticia Corrales et al. Cell Reports
- Soluble Interleukin-15 Complexes Are Generated In Vivo by Type I Interferon Dependent and Independent Pathways
- (2015) Scott M. Anthony et al. PLoS One
- IL-15-dependent CD8+CD122+T cells ameliorate experimental autoimmune encephalomyelitis by modulating IL-17 production by CD4+T cells
- (2014) Ping Yu et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors
- (2014) Seng-Ryong Woo et al. IMMUNITY
- STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
- (2014) Liufu Deng et al. IMMUNITY
- Functional Network Pipeline Reveals Genetic Determinants Associated with in Situ Lymphocyte Proliferation and Survival of Cancer Patients
- (2014) B. Mlecnik et al. Science Translational Medicine
- Systemic 4-1BB activation induces a novel T cell phenotype driven by high expression of Eomesodermin
- (2013) Michael A. Curran et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Homeostasis of Human NK Cells Is Not IL-15 Dependent
- (2013) H. Lebrec et al. JOURNAL OF IMMUNOLOGY
- Transcriptional Regulation of IL-15 Expression during Hematopoiesis
- (2013) S. L. Colpitts et al. JOURNAL OF IMMUNOLOGY
- CD8 + Dendritic Cell Trans Presentation of IL-15 to Naive CD8+ T Cells Produces Antigen-Inexperienced T Cells in the Periphery with Memory Phenotype and Function
- (2013) T. Sosinowski et al. JOURNAL OF IMMUNOLOGY
- Elevated CD3+ and CD8+ tumor-infiltrating immune cells correlate with prolonged survival in glioblastoma patients despite integrated immunosuppressive mechanisms in the tumor microenvironment and at the systemic level
- (2013) Justyna Kmiecik et al. JOURNAL OF NEUROIMMUNOLOGY
- IL-15 in tumor microenvironment causes rejection of large established tumors by T cells in a noncognate T cell receptor-dependent manner
- (2013) R. B. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tumor-infiltrating Lymphocytes, Tumor Characteristics, and Recurrence in Patients With Early Breast Cancer
- (2012) Seung Tae Kim et al. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
- Circulating IL-15 exists as heterodimeric complex with soluble IL-15R in human and mouse serum
- (2012) C. Bergamaschi et al. BLOOD
- Inflammatory Monocytes Activate Memory CD8+ T and Innate NK Lymphocytes Independent of Cognate Antigen during Microbial Pathogen Invasion
- (2012) Saïdi M'Homa Soudja et al. IMMUNITY
- Cutting Edge: The Role of IFN- Receptor and MyD88 Signaling in Induction of IL-15 Expression In Vivo
- (2012) S. L. Colpitts et al. JOURNAL OF IMMUNOLOGY
- Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
- (2012) P. Yu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Host type I IFN signals are required for antitumor CD8+T cell responses through CD8α+dendritic cells
- (2011) Mercedes B. Fuertes et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Thymic and peripheral microenvironments differentially mediate development and maturation of iNKT cells by IL-15 transpresentation
- (2010) E. F. Castillo et al. BLOOD
- TheN-Ethyl-N-Nitrosourea-InducedGoldenticketMouse Mutant Reveals an Essential Function ofStingin theIn VivoInterferon Response toListeria monocytogenesand Cyclic Dinucleotides
- (2010) John-Demian Sauer et al. INFECTION AND IMMUNITY
- MHC Class I and TCR Avidity Control the CD8 T Cell Response to IL-15/IL-15R Complex
- (2010) T. A. Stoklasek et al. JOURNAL OF IMMUNOLOGY
- Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice
- (2010) Noah Saederup et al. PLoS One
- Inflammatory Monocytes Facilitate Adaptive CD4 T Cell Responses during Respiratory Fungal Infection
- (2009) Tobias M. Hohl et al. Cell Host & Microbe
- Macrophage- and Dendritic-Cell-Derived Interleukin-15 Receptor Alpha Supports Homeostasis of Distinct CD8+ T Cell Subsets
- (2009) Erwan Mortier et al. IMMUNITY
- Trans-Presentation of IL-15 by Intestinal Epithelial Cells Drives Development of CD8 IELs
- (2009) L. J. Ma et al. JOURNAL OF IMMUNOLOGY
- Dendritic Cells Support the In Vivo Development and Maintenance of NK Cells via IL-15 Trans-Presentation
- (2009) E. F. Castillo et al. JOURNAL OF IMMUNOLOGY
- Dendritic cells drive memory CD8 T-cell homeostasis via IL-15 transpresentation
- (2008) S. W. Stonier et al. BLOOD
- IL-15Rα chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation
- (2008) Erwan Mortier et al. JOURNAL OF EXPERIMENTAL MEDICINE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now