Dietary macronutrients and the gut microbiome: a precision nutrition approach to improve cardiometabolic health

The baseline gut microbiota directs dieting-induced weight loss trajectories

(2021) Zhuye Jie et al.   GASTROENTEROLOGY

The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk

(2021) Dong D. Wang et al.   NATURE MEDICINE

Association Between Gut Akkermansia and Metabolic Syndrome is Dose-Dependent and Affected by Microbial Interactions: A Cross-Sectional Study

(2021) Qi Zhou et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Effect on gut microbiota of a 1-y lifestyle intervention with Mediterranean diet compared with energy-reduced Mediterranean diet and physical activity promotion: PREDIMED-Plus Study

(2021) Jananee Muralidharan et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Gut Microbiota Profile and Its Association with Clinical Variables and Dietary Intake in Overweight/Obese and Lean Subjects: A Cross-Sectional Study

(2021) Judit Companys et al.   Nutrients

Discovery of the gut microbial signature driving the efficacy of prebiotic intervention in obese patients

(2020) Julie Rodriguez et al.   GUT

Current metabolic perspective on malnutrition in obesity: towards more subgroup-based nutritional approaches?

(2020) Ellen E. Blaak   PROCEEDINGS OF THE NUTRITION SOCIETY

Effect of wheat bran derived prebiotic supplementation on gastrointestinal transit, gut microbiota, and metabolic health: a randomized controlled trial in healthy adults with a slow gut transit

(2020) Mattea Müller et al.   Gut Microbes

Individual and cohort-specific gut microbiota patterns associated with tissue-specific insulin sensitivity in overweight and obese males

(2020) Gerben D. A. Hermes et al.   Scientific Reports

Human postprandial responses to food and potential for precision nutrition

(2020) Sarah E. Berry et al.   NATURE MEDICINE

Towards personalized microbial substrates for metabolic health

(2020) Emanuel E. Canfora et al.   Nature Reviews Endocrinology

Gut microbiota in human metabolic health and disease

(2020) Yong Fan et al.   NATURE REVIEWS MICROBIOLOGY

Gut bacteria Akkermansia is associated with reduced risk of obesity: evidence from the American Gut Project

(2020) Qi Zhou et al.   Nutrition & Metabolism

Short chain fatty acids in human gut and metabolic health

(2020) E.E. Blaak et al.   Beneficial Microbes

Gut microbiota-derived metabolites as central regulators in metabolic disorders

(2020) Allison Agus et al.   GUT

Gut microbial metabolites in obesity, NAFLD and T2DM

(2019) Emanuel E. Canfora et al.   Nature Reviews Endocrinology

Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases

(2019) Serena Sanna et al.   NATURE GENETICS

Effects of dietary fat on gut microbiota and faecal metabolites, and their relationship with cardiometabolic risk factors: a 6-month randomised controlled-feeding trial

(2019) Yi Wan et al.   GUT

Stereotypes About Enterotype: the Old and New Ideas

(2019) Mingyue Cheng et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study

(2019) Clara Depommier et al.   NATURE MEDICINE

Regulation of energy expenditure and substrate oxidation by short-chain fatty acids

(2019) Alia H Sukkar et al.   JOURNAL OF ENDOCRINOLOGY

Prevotella Abundance Predicts Weight Loss Success in Healthy, Overweight Adults Consuming a Whole-Grain Diet Ad Libitum: A Post Hoc Analysis of a 6-Wk Randomized Controlled Trial

(2019) Lars Christensen et al.   JOURNAL OF NUTRITION

Gut Microbiome Fermentation Determines the Efficacy of Exercise for Diabetes Prevention

(2019) Yan Liu et al.   Cell Metabolism

Gut Microbiota and Obesity: A Role for Probiotics

(2019) Ludovico Abenavoli et al.   Nutrients

Distal colonic transit is linked to gut microbiota diversity and microbial fermentation in humans with slow colonic transit

(2019) Mattea Müller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Vitamins for the Gut Microbiome

(2019) Robert E. Steinert et al.   TRENDS IN MOLECULAR MEDICINE

OUP accepted manuscript

(2018)   AMERICAN JOURNAL OF CLINICAL NUTRITION

Habitual dietary fibre intake influences gut microbiota response to an inulin-type fructan prebiotic: a randomised, double-blind, placebo-controlled, cross-over, human intervention study

(2018) Genelle Healey et al.   BRITISH JOURNAL OF NUTRITION

An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans

(2018) Adil Mardinoglu et al.   Cell Metabolism

Dietary fat and gut microbiota: mechanisms involved in obesity control

(2018) Olívia Gonçalves Leão Coelho et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Obesity treatment by epigallocatechin-3-gallate–regulated bile acid signaling and its enriched Akkermansia muciniphila

(2018) Lili Sheng et al.   FASEB JOURNAL

The gut microbiota metabolite indole alleviates liver inflammation in mice

(2018) Martin Beaumont et al.   FASEB JOURNAL

Major microbiota dysbiosis in severe obesity: fate after bariatric surgery

(2018) Judith Aron-Wisnewsky et al.   GUT

Prevotella-to-Bacteroides ratio predicts body weight and fat loss success on 24-week diets varying in macronutrient composition and dietary fiber: results from a post-hoc analysis

(2018) Mads F. Hjorth et al.   INTERNATIONAL JOURNAL OF OBESITY

Short-chain fatty acids suppress food intake by activating vagal afferent neurons

(2018) Chayon Goswami et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes

(2018) Liping Zhao et al.   SCIENCE

Gastrointestinal Transit Time, Glucose Homeostasis and Metabolic Health: Modulation by Dietary Fibers

(2018) et al.   Nutrients

Considerations for Best Practices in Studies of Fiber or Other Dietary Components and the Intestinal Microbiome

(2018) David M. Klurfeld et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Influence of Early Life, Diet, and the Environment on the Microbiome

(2018) Tien S. Dong et al.   Clinical Gastroenterology and Hepatology

Interplay between food and gut microbiota in health and disease

(2018) Niels Banhos Danneskiold-Samsøe et al.   FOOD RESEARCH INTERNATIONAL

Environment dominates over host genetics in shaping human gut microbiota

(2018) Daphna Rothschild et al.   NATURE

Dietary fat, the gut microbiota, and metabolic health – A systematic review conducted within the MyNewGut project

(2018) Maike Wolters et al.   CLINICAL NUTRITION

Gut microbiota composition in relation to the metabolic response to 12-week combined polyphenol supplementation in overweight men and women

(2017) J Most et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Supplementation of Diet With Galacto-oligosaccharides Increases Bifidobacteria, but Not Insulin Sensitivity, in Obese Prediabetic Individuals

(2017) Emanuel E. Canfora et al.   GASTROENTEROLOGY

Role of the Gut Microbiome in the Pathogenesis of Obesity and Obesity-Related Metabolic Dysfunction

(2017) Kristien E. Bouter et al.   GASTROENTEROLOGY

Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit

(2017) Zhuang Li et al.   GUT

Soluble Dietary Fiber Reduces Trimethylamine Metabolism via Gut Microbiota and Co-Regulates Host AMPK Pathways

(2017) Qian Li et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites

(2017) Dylan Dodd et al.   NATURE

Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

(2017) Yan Zheng et al.   Nature Reviews Endocrinology

Gut microbiome as a clinical tool in gastrointestinal disease management: are we there yet?

(2017) Eamonn M. M. Quigley   Nature Reviews Gastroenterology & Hepatology

Gut microbiota composition strongly correlates to peripheral insulin sensitivity in obese men but not in women

(2017) J. Most et al.   Beneficial Microbes

Economic Burden of Obesity: A Systematic Literature Review

(2017) Maximilian Tremmel et al.   International Journal of Environmental Research and Public Health

Geography, Ethnicity or Subsistence-Specific Variations in Human Microbiome Composition and Diversity

(2017) Vinod K. Gupta et al.   Frontiers in Microbiology

Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight/obese men: a randomized crossover trial

(2017) Emanuel E. Canfora et al.   Scientific Reports

Fructooligosaccharide (FOS) and Galactooligosaccharide (GOS) Increase Bifidobacterium but Reduce Butyrate Producing Bacteria with Adverse Glycemic Metabolism in healthy young population

(2017) Feitong Liu et al.   Scientific Reports

Age-related changes in gut microbiota composition from newborn to centenarian: a cross-sectional study

(2016) Toshitaka Odamaki et al.   BMC MICROBIOLOGY

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

Effects of Gut Microbiota Manipulation by Antibiotics on Host Metabolism in Obese Humans: A Randomized Double-Blind Placebo-Controlled Trial

(2016) Dorien Reijnders et al.   Cell Metabolism

Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity

(2016) Dariush Mozaffarian   CIRCULATION

Distal, not proximal, colonic acetate infusions promote fat oxidation and improve metabolic markers in overweight/obese men

(2016) C. M. van der Beek et al.   CLINICAL SCIENCE

Formation of propionate and butyrate by the human colonic microbiota

(2016) Petra Louis et al.   ENVIRONMENTAL MICROBIOLOGY

Systemic availability and metabolism of colonic-derived short-chain fatty acids in healthy subjects: a stable isotope study

(2016) Eef Boets et al.   JOURNAL OF PHYSIOLOGY-LONDON

Gut microbiota, diet, and obesity-related disorders-The good, the bad, and the future challenges

(2016) Kevin J. Portune et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Human gut microbes impact host serum metabolome and insulin sensitivity

(2016) Helle Krogh Pedersen et al.   NATURE

Signals from the gut microbiota to distant organs in physiology and disease

(2016) Bjoern O Schroeder et al.   NATURE MEDICINE

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

(2016) Alexandra Zhernakova et al.   SCIENCE

Population-level analysis of gut microbiome variation

(2016) Gwen Falony et al.   SCIENCE

Bifidobacteria and Butyrate-Producing Colon Bacteria: Importance and Strategies for Their Stimulation in the Human Gut

(2016) Audrey Rivière et al.   Frontiers in Microbiology

Infant Gut Microbiota Development Is Driven by Transition to Family Foods Independent of Maternal Obesity

(2016) Martin Frederik Laursen et al.   mSphere

The protein source determines the potential of high protein diets to attenuate obesity development in C57BL/6J mice

(2016) Ulrike Liisberg et al.   Adipocyte

Associations of gut-flora-dependent metabolite trimethylamine-N-oxide, betaine and choline with non-alcoholic fatty liver disease in adults

(2016) Yu-ming Chen et al.   Scientific Reports

Relationship of Serum Trimethylamine N-Oxide (TMAO) Levels with early Atherosclerosis in Humans

(2016) Elko Randrianarisoa et al.   Scientific Reports

Changes in intake of protein foods, carbohydrate amount and quality, and long-term weight change: results from 3 prospective cohorts

(2015) Jessica D Smith et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

A Randomised Crossover Trial: The Effect of Inulin on Glucose Homeostasis in Subtypes of Prediabetes

(2015) Nicola D. Guess et al.   ANNALS OF NUTRITION AND METABOLISM

Increased gut hormones and insulin sensitivity index following a 3-d intervention with a barley kernel-based product: a randomised cross-over study in healthy middle-aged subjects

(2015) Anne C. Nilsson et al.   BRITISH JOURNAL OF NUTRITION

Personalized Nutrition by Prediction of Glycemic Responses

(2015) David Zeevi et al.   CELL

Dietary Fiber-Induced Improvement in Glucose Metabolism Is Associated with Increased Abundance of Prevotella

(2015) Petia Kovatcheva-Datchary et al.   Cell Metabolism

The influence of diet on the gut microbiota and its consequences for health

(2015) Joël Doré et al.   CURRENT OPINION IN BIOTECHNOLOGY

Soybean Antigen Proteins and their Intestinal Sensitization Activities

(2015) Long He et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Short-Chain Fatty Acids Protect Against High-Fat Diet–Induced Obesity via a PPARγ-Dependent Switch From Lipogenesis to Fat Oxidation

(2015) Gijs den Besten et al.   DIABETES

GPR43 Potentiates β-Cell Function in Obesity

(2015) Joanne C. McNelis et al.   DIABETES

The insulin resistance phenotype (muscle or liver) interacts with the type of diet to determine changes in disposition index after 2 years of intervention: the CORDIOPREV-DIAB randomised clinical trial

(2015) Ruth Blanco-Rojo et al.   DIABETOLOGIA

Dietary fibre and incidence of type 2 diabetes in eight European countries: the EPIC-InterAct Study and a meta-analysis of prospective studies

(2015)   DIABETOLOGIA

How informative is the mouse for human gut microbiota research?

(2015) T. L. A. Nguyen et al.   Disease Models & Mechanisms

Proton pump inhibitors affect the gut microbiome

(2015) Floris Imhann et al.   GUT

Akkermansia muciniphilaand improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology

(2015) Maria Carlota Dao et al.   GUT

An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

(2015) Medha Priyadarshini et al.   MOLECULAR ENDOCRINOLOGY

Short-chain fatty acids in control of body weight and insulin sensitivity

(2015) Emanuel E. Canfora et al.   Nature Reviews Endocrinology

Sex, Body Mass Index, and Dietary Fiber Intake Influence the Human Gut Microbiome

(2015) Christine Dominianni et al.   PLoS One

High-protein diet modifies colonic microbiota and luminal environment but not colonocyte metabolism in the rat model: the increased luminal bulk connection

(2014) Xinxin Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Human Genetics Shape the Gut Microbiome

(2014) Julia K. Goodrich et al.   CELL

Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits

(2014) Filipe De Vadder et al.   CELL

A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increasedAkkermansiaspp. population in the gut microbiota of mice

(2014) Fernando F Anhê et al.   GUT

Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults

(2014) Edward S Chambers et al.   GUT

Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men

(2014) Anne Salonen et al.   ISME Journal

Dietary trimethylamine N-oxide exacerbates impaired glucose tolerance in mice fed a high fat diet

(2014) Xiang Gao et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Gut Microbiota Signatures Predict Host and Microbiota Responses to Dietary Interventions in Obese Individuals

(2014) Katri Korpela et al.   PLoS One

Gut microbiota and energy balance: role in obesity

(2014) Michael Blaut   PROCEEDINGS OF THE NUTRITION SOCIETY

The Impact of Diet and Lifestyle on Gut Microbiota and Human Health

(2014) Michael Conlon et al.   Nutrients

Bacterial Metabolite Indole Modulates Incretin Secretion from Intestinal Enteroendocrine L Cells

(2014) Catalin Chimerel et al.   Cell Reports

Sodium acetate decreases phosphorylation of hormone sensitive lipase in isoproterenol-stimulated 3T3-L1 mature adipocytes

(2014) Nicola Aberdein et al.   Adipocyte

Diet, microbiota, and microbial metabolites in colon cancer risk in rural Africans and African Americans

(2013) Junhai Ou et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The association of whole grain consumption with incident type 2 diabetes: the Women's Health Initiative Observational Study

(2013) Emily D. Parker et al.   ANNALS OF EPIDEMIOLOGY

Endogenous hydrogen sulfide protects pancreatic beta-cells from a high-fat diet-induced glucotoxicity and prevents the development of type 2 diabetes

(2013) Mitsuhiro Okamoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Disruption of the gut microbiome as a risk factor for microbial infections

(2013) Arya Khosravi et al.   CURRENT OPINION IN MICROBIOLOGY

Butyrate Attenuates Inflammation and Lipolysis Generated by the Interaction of Adipocytes and Macrophages

(2013) Hideo Ohira et al.   Journal of Atherosclerosis and Thrombosis

Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity

(2013) Anne Vrieze et al.   JOURNAL OF HEPATOLOGY

A Mixture of trans-Galactooligosaccharides Reduces Markers of Metabolic Syndrome and Modulates the Fecal Microbiota and Immune Function of Overweight Adults

(2013) Jelena Vulevic et al.   JOURNAL OF NUTRITION

Habitual Dietary Intake Is Associated with Stool Microbiota Composition in Monozygotic Twins

(2013) Catarina D. Simões et al.   JOURNAL OF NUTRITION

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Dietary intervention impact on gut microbial gene richness

(2013) Aurélie Cotillard et al.   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Gut metagenome in European women with normal, impaired and diabetic glucose control

(2013) Fredrik H. Karlsson et al.   NATURE

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity

(2013) J. G. M. Markle et al.   SCIENCE

Impact of Short Term Consumption of Diets High in Either Non-Starch Polysaccharides or Resistant Starch in Comparison with Moderate Weight Loss on Indices of Insulin Sensitivity in Subjects with Metabolic Syndrome

(2013) Gerald Lobley et al.   Nutrients

Fiber and Prebiotics: Mechanisms and Health Benefits

(2013) Joanne Slavin   Nutrients

Saturated fat stimulates obesity and hepatic steatosis and affects gut microbiota composition by an enhanced overflow of dietary fat to the distal intestine

(2012) Nicole de Wit et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome

(2012) Anne Vrieze et al.   GASTROENTEROLOGY

Insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women

(2012) Evelyne M Dewulf et al.   GUT

Microbiota conservation and BMI signatures in adult monozygotic twins

(2012) Sebastian Tims et al.   ISME Journal

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Human gut microbiome viewed across age and geography

(2012) Tanya Yatsunenko et al.   NATURE

The influence of diet on the gut microbiota

(2012) Karen P. Scott et al.   PHARMACOLOGICAL RESEARCH

Intestinal luminal nitrogen metabolism: Role of the gut microbiota and consequences for the host

(2012) Anne-Marie Davila et al.   PHARMACOLOGICAL RESEARCH

Dietary macronutrients and food consumption as determinants of long-term weight change in adult populations: a systematic literature review

(2012) Mikael Fogelholm et al.   Food & Nutrition Research

High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health

(2011) Wendy R Russell et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Functional analysis of colonic bacterial metabolism: relevant to health?

(2011) Henrike M. Hamer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Feed ingredients differing in fermentable fibre and indigestible protein content affect fermentation metabolites and faecal nitrogen excretion in growing pigs

(2011) R. Jha et al.   Animal

Relevance of protein fermentation to gut health

(2011) Karen Windey et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Dominant and diet-responsive groups of bacteria within the human colonic microbiota

(2010) Alan W Walker et al.   ISME Journal

Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults

(2010) Nadja Larsen et al.   PLoS One

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

(2010) C. De Filippo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal

(2009) Patrice D Cani et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Effects of Acetate on Lipid Metabolism in Muscles and Adipose Tissues of Type 2 Diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) Rats

(2009) Hiromi YAMASHITA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice

(2009) Z. Gao et al.   DIABETES

Microbiota and SCFA in Lean and Overweight Healthy Subjects

(2009) Andreas Schwiertz et al.   Obesity

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

(2009) P. J. Turnbaugh et al.   Science Translational Medicine

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe

Human colonic microbiota associated with diet, obesity and weight loss

(2008) S H Duncan et al.   INTERNATIONAL JOURNAL OF OBESITY

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE